Clinical trials: Oocytes
Influenza, Human
Recombinant Influenza Vaccine Versus Standard Egg-Based Inactivated Influenza Vaccine in Adults 18-64 Years
This randomized, active comparator trial will compare the clinical efficacy of recombinant influenza vaccine (RIV) to standard-dose egg-based inactivated influenza vaccine (SD IIV) among adults aged 18-64 years.
- Trial name
- NCT05514002
- Testing
- Fluzone Quadrivalent, Flublok Quadrivalent
- Where
- 4 sites in United States
- Volunteers
- 3,988 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Gastroparesis, Diabetes Complications
To Study the EGG Abnormalities in Healthy Subjects and in Patients With Idiopathic and Diabetic Gastroparesis.
Electrogastrogram (EGG) is a non-invasive method for recording myoelectric activities by placing electrodes on the abdomen surface.
- Conditions
- Gastroparesis, Diabetes Complications, Idiopathic Gastric Motility Disorder, Dyspepsia
- Trial name
- NCT05624034
- Testing
- Electrogastrography
- Where
- India
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Infertility
Novel Approach With Double Agent Artificial Oocyte Activation for Repeated Fertilization Failure Due to Combined Sperm and Oocyte Factor
Novel approach for Oocyte fertilization failure for difficult cases not respond to traditional methods of assisted reproduction as intracytoplasmic sperm injection.
- Trial name
- CISC (NCT02418416)
- Testing
- Oocyte double chemical activation
- Where
- 3 sites in Bahrain, Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ibn Sina Hospital
Infertility
IVF Treatment in Women With Immature Oocytes in Previous Cycle
In standard IVF stimulation cycle,human chorionic gonadotropin (hCG) is usually used at the end of controlled ovarian hyperstimulation (COH) as a surrogate to only the luteinizing hormone (LH) surge.
- Trial name
- NCT02368964
- Testing
- GnRH agonist 0.2 mg + hCG 250 mcg, high dose hCG 500 mcg
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Egg Allergy, Cow's Milk Allergy
Cow's Milk and Hen's Egg Hyposensitization in Adults
Egg, milk and cereal allergies are the most important food allergies in Finnish children, the prevalence in western countries is 1-4 %. In some individuals food-allergy is maintained in to adulthood.
- Trial name
- NCT02083471
- Testing
- Specific Oral Tolerance Induction with Egg or Cow's milk
- Volunteers
- 40 people
- Sponsor
- Turku University Hospital
Premature Luteinisation, Progesterone Elevation
Ovarian Stimulation With FSH Alone Versus FSH Plus GnRH Antagonist in an Oocyte Donor/Recipient Programme
The aim of this study is to compare the efficacy of a protocol using FSH alone with that of a protocol using FSH plus a GnRH antagonist for controlled ovarian hyperstimulation in cycles of elective freezing in the context of a…
- Trial name
- NCT05759871
- Testing
- GnRH antagonist
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
IVF Outcomes
Ovarian Stimulation Outcomes During a GnRH Antagonist Protocol for In-vitro Fertilization When Comparing Trigger Day Decision by Physicians Versus an Artificial Intelligence-based Algorithm.
To compare the number of mature oocytes following a GnRH antagonist in-vitro fertilization stimulation cycle when comparing trigger day timing decision by physicians versus an artificial intelligence-based algorithm
- Trial name
- NCT07110285
- Testing
- Artificial intelligence-based algorithm
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- FertilAI
Egg Donation
Efficacy of Recombinant FSH/GnRH Antagonist Protocol With and Without LH Adjunct for Egg Bank Donation
Disprove the null hypothesis as follows: Among the investigator's egg bank donors undergoing ovulation induction with recombinant FSH medication per treatment protocol outlined below, use of adjunctive LH activity medication…
- Trial name
- NCT02069808
- Testing
- Follistim, Ganirelix, Menotropins
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Michigan Reproductive Medicine
Infertility
Use of a Synthetic Macromolecule (Hydroxypropyl Cellulose ) and Trehalose as Additives for Oocyte Vitrification
This study is aimed to evaluate the use of Hydroxypropyl Cellulose (HPC) as substitute for the traditional protein supplement (Synthetic Serum Substitute; SSS) and Trehalose as substitute for the most widely used sugar (Sucrose)…
- Trial name
- NCT01745523
- Testing
- Synthetic macromolecule HPC and trehalose, SSS containing HSA and sucrose
- Where
- Spain
- Volunteers
- 440 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Exercise Training, Dietary Supplements
Egg White Supplementation in High-Intensity Functional Training
High-intensity functional training (HIFT), a new version of high-intensity interval training, has gained interest in recent years.
- Trial name
- NCT05396963
- Testing
- Egg white, Whey protein, Maltodextrin
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
BMI, Lipid Profile
The Influence of Obesity on Oocyte, Cumulus and Granulosa Functioning
Obese women have a higher prevalence of infertility than their lean counterparts. Obesity is a risk factor for anovulation , including in response to gonadotropin treatment .Further, even in women who are cycling regularly…
- Trial name
- NCT01945671
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Influenza
Safety, Tolerability and Immunogenicity of NBP607QIV in Healthy Adult Volunteers
This study assesses safety, tolerability and immunogenicity of NBP607QIV to Agrippal which are indicated for active immunization for the prevention of influenza disease.
- Trial name
- NCT03826719
- Testing
- NBP607QIV, Agrippal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- SK Chemicals Co., Ltd.
Infertility, In Vitro Maturation of Oocytes
Aspire In Vitro Maturation Study
A study to assess the Capacitation - in-vitro maturation (CAPA-IVM) system as an option for patients with a good ovarian reserve to achieve pregnancy.
- Conditions
- Infertility, In Vitro Maturation of Oocytes, Assisted Reproduction Technologies
- Trial name
- AIM (NCT07789730)
- Testing
- CAPA-IVM
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Inception Fertility Research Institute, LLC
Oxidative Stress
Association Between Oxidative Parameters in Fertilization Medium of Cumulus Oocyte Complex and Outcome in IVF
Medium of cumulus-oocyte complex will be assessed for oxidative status.
- Trial name
- NCT03382002
- Testing
- TCL
- Where
- Israel
- Volunteers
- 322 people
- Sponsor
- Carmel Medical Center
IgE-Mediated Food Allergy, Peanut Allergy
A 52-week Study of Remibrutinib in IgE-mediated Food Allergy
The purpose of this Phase III study is to evaluate the clinical efficacy and safety of remibrutinib in participants with peanut, or cow's milk ("milk", cooked and uncooked) or hen's egg ("egg", cooked and uncooked) immunoglobulin…
- Conditions
- IgE-Mediated Food Allergy, Peanut Allergy, Cow Milk Allergy, Egg Allergy
- Trial name
- NCT07768371
- Testing
- Remibrutinib
- Where
- 18 sites in United States
- Volunteers
- 576 people
- Sponsor
- Novartis Pharmaceuticals
Food Allergy
ADP101 for Oral Immunotherapy in Food-Allergic Children and Adults
The purpose of this study is to assess the efficacy and safety of ADP101 in food allergic children and adults.
- Trial name
- NCT04856865
- Testing
- Low dose ADP101, High dose ADP101
- Where
- 15 sites in United States
- Volunteers
- 73 people
- Sponsor
- Alladapt Immunotherapeutics, Inc.
Infertility, Female, Reproductive Techniques, Assisted
SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques
The goal of this clinical trial is to learn whether two different methods of helping eggs and sperm join-intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (IVF)-lead to better embryo development when…
- Conditions
- Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
- Trial name
- SISTER (NCT07175571)
- Testing
- Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Protein Malnutrition
Formative Research Study to Address Protein Intake in Children and Analysis of Breast Milk Nutrient Content in Mothers
This formative research seeks to explore the use of egg (as a potential source of protein) as nutritional supplement for young children aged 6-8 months of either sex and breast milk composition of mothers of infants under 6…
- Trial name
- NCT03140696
- Testing
- Egg Alone, Egg and ready to use supplementary food (RUSF), Egg and breast milk
- Where
- Bangladesh
- Volunteers
- 30 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Female Reproductive Problem, Infertility
Use of Corifolitropin Alfa in Oocyte Donors
The purpose of this study is to determine if corifollitropin alfa (long-term gonadotropin administration) is effective in a controlled ovarian stimulation protocol in oocyte donors compared to daily gonadotropin administration…
- Trial name
- NCT02213627
- Testing
- Corifollitropin alfa, Recombinant FSH, HP-hMG
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Colitis, Ulcerative
Trichuris Suis Ova Treatment in Left-sided Ulcerative Colitis
The purpose of this study is to evaluate the safety and effectiveness of trichuris suis ova (TSO) in ulcerative colitis (UC). We will look at how TSO affects the body's immune response and if there are related changes in…
- Trial name
- NCT01953354
- Testing
- Trichuris suis ova (TSO)
- Where
- 17 sites in United States
- Volunteers
- 16 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)