Clinical trials: Oocytes
Biomarkers of Cardiovascular Disease
Plasma and Urine TMAO Formation and Changes to Oxidized LDL After Ingestion of Different Amounts of Egg
Eggs contain an essential nutrient called choline and adequate levels of choline are required for good health. Studies in mice have demonstrated that high levels of choline may increase risk of heart disease through a process…
- Trial name
- NCT01906554
- Testing
- Egg Dose
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Infertility
The Evaluation of a Preparatory Information Movie on Oocyte Aspiration
The Preparatory information on Oocyte Aspiration Movie Randomized Controlled Trial (POAM-RCT) primarily aims to evaluate whether a new preparatory information on oocyte aspiration movie (POAM) decreases the anxiety of women on…
- Trial name
- POAM-RCT (NCT03717805)
- Testing
- POAM
- Where
- Belgium
- Volunteers
- 155 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Food Allergy
Trichuris Suis Ova in Peanut and Tree Nut Allergy
The goal of this study is to determine whether Trichuris suis ova, a potential immunomodulator, is safe in adults and children allergic to peanut or tree nuts.
- Trial name
- NCT01070498
- Testing
- Trichuris suis ova (TSO)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Beth Israel Deaconess Medical Center
Fertility Issues
Follicular FSH Serum Level as a Predictor of an Oocyte Yield and Quality in Fertility Preservation Cycles for Women With a Compromised Ovarian Reserve
The incorporation of ovarian reserve tests in IVF management started after initial publications indicating a potential role for basal FSH in predicting pregnancy outcome after IVF and in counseling patients (1,2).
- Trial name
- NCT05536999
- Testing
- Blood sample taking , like to measure hormonal level like LH, FSH, Perlakan ,in a follicular fluid after the oocyte retrival
- Where
- Israel
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Infertility, Donor Oocyte Assisted Reproduction
Fresh Versus Vitrified-Warmed Donor Oocytes: Embryological and Clinical Outcomes
This multicenter retrospective observational study compares embryological and clinical outcomes following treatment with fresh versus vitrified-warmed donor oocytes at Bocian Fertility Clinic centers in Poland.
- Trial name
- FRESH-FROZEN (NCT07904936)
- Testing
- Fresh Donor Oocyte ICSI, Vitrified-Warmed Donor Oocyte ICSI
- Where
- Poland
- Volunteers
- 3,000 people
- Sponsor
- Center for Reproductive Medicine Bocian
Infertility
Ultrasound-guided Hydrosalpinx Aspiration During Egg Collection
· What we know: Hydrosalpinx and IVF About 40% of patients undergoing IVF have tubal disease and in 25%-30% of tubal disease patients there is fluid collection within the tube; hydrosalpinx.
- Trial name
- NCT00566956
- Testing
- Hydrosalpinx needle aspiration to arm 1
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Fertilization
Mechanical Stimulation Improve the Fertilization in ICSI Cycle
Most fertilization failures after ICSI are caused by failure of oocyte activation defects. But, to date, there is no effective method to overcome this obstacle.
- Trial name
- NCT03810001
- Testing
- Mechanical Stimulation
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Ovarian Stimulation
Conventional Ovarian Stimulation vs. Single Injection Stimulation of Corifollitropin Alfa in Oocyte Donor
This study aims to study the efficiency of using a single injection of Corifollitropin alfa for ovarian stimulation by initiating administration late and without further administration of follicle-stimulating hormone after the…
- Trial name
- TAIL (NCT03939403)
- Testing
- Time of administration of Corifollitropin Alfa
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Infertility
The Cytogenetic Constitution of Embryos Resulting From Immature Oocytes (M1)
To examine the chromosomal number content in the blastomeres of embryos achieved from fertilization of immature oocytes at MI stage recruited following COH for IVF.
- Trial name
- NCT00544531
- Where
- Israel
- Volunteers
- 23,907 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
IVF, Infertility
Second Ovulation Induction
Studies reported various risk factors for inadequate ovulation induction such as body mass index, low ovarian reserve, low baseline FSH and LH, and previous use of contraception or agonist.
- Trial name
- NCT06502665
- Testing
- Women having had second ovulation induction after failed oocyte pick-up
- Where
- Canada
- Volunteers
- 87 people
- Sponsor
- Clinique Ovo
Fertilization, Fertilization in Vitro
BEst Size for Ovulation Triggering in Poseidon 4 Patients (BEST 4 Study)
This observational clinical study aims to determine the optimal timing of ovulation triggering in women aged 35 and above with poor ovarian reserve.
- Trial name
- BEST (NCT06433518)
- Testing
- Ovulation Trigger Timing Based on Leading Follicle Size in POSEIDON Group 4 IVF Patients
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Centrum Clinic IVF Center
Infertility
Perifollicular Vascularity Assessment in in-Vitro Fertilization
On February 2004, a law (n. 40/2004) regulating assisted reproduction techniques (ARTs) was approved in Italy. This law aimed to regulate the treatment of infertility in Italy, contains several restrictions, such as the…
- Trial name
- NCT00458380
- Testing
- Controlled ovarian stimulation, perifollicular vascularity assessment, IVF, embryo transfer.
- Where
- Italy
- Volunteers
- 116 people
- Sponsor
- University Magna Graecia
Influenza
Comparison of the Immunogenicity, Safety and Reactogenicity of FluBlok, To a Licensed Vaccine In Elderly Adults
The purpose of this study were to obtain additional evidence in support of the safety and immunogenicity of a recombinant hemagglutinin (rHA) vaccine in an elderly population, and to establish non-inferiority of the…
- Trial name
- NCT00395174
- Testing
- Influenza Vaccination
- Where
- 7 sites in United States
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- Protein Sciences Corporation
Infertility, Premature Ovarian Failure
Single Follicular Dexarelix for LH Suppression During Ovarian Stimulation in Oocyte Donors.
A randomized prospective study in the evaluation of the long acting GnRH antagonist Degarelix against the classical multidose regime with Ganirelix for LH suppression during the follicular phase of an ovarian stimulation cycle in…
- Trial name
- NCT03861715
- Testing
- live birth rate
- Where
- Greece
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
Type 2 Diabetes, Heart Diseases
Egg Intake and Risk of Type 2 Diabetes
This is a longitudinal study that will collect demographic, anthropometric and dietary data to determine the relationships between meat and egg intake and the incidence of Type 2 Diabetes.
- Trial name
- ES (NCT03406910)
- Where
- United States
- Volunteers
- 55,851 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Influenza
Safety and Immunogenicity Study of an Inactivated Influenza Vaccine (Whole Virion, Vero Cell Derived)
The objective of this study is to assess the safety and immunogenicity of inactivated influenza vaccine (whole virion, Vero cell derived).
- Trial name
- NCT00289510
- Testing
- Inactivated influenza vaccine (whole virion, Vero cell-derived), Inactivated influenza vaccine (egg derived) [licensed control vaccine]
- Where
- 3 sites in Austria, Germany
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Alachua Government Services, Inc.
Egg Allergy
Pancake Oral Immunotherapy For Egg Allergy In Inducing Tolerance
Oral immunotherapy (OIT) using raw/ cooked egg has good desensitisation outcomes but is associated with frequent and sometimes severe adverse events (anaphylaxis is not uncommon).
- Trial name
- POET (NCT07192510)
- Testing
- Pancake oral immunotherapy
- Where
- Singapore
- Volunteers
- 23 people
- Sponsor
- KK Women's and Children's Hospital
Infertility
Experience of Pain During Oocyte Retrieval- a Comparison Between Two Aspiration Needles
The purpose of the study is to compare the pain experience between the patients that have had their transvaginal oocytes retrieval with ultrasound guidance performed with reduced single lumen needle (Vitrolife Sweden AB…
- Trial name
- NCT00924885
- Testing
- Swemed Follicle Aspiration Set Reduced Single Lumen, Swemed Follicle Aspiration Set Single Lumen (1.4 mm)
- Where
- 4 sites in Sweden
- Volunteers
- 257 people
- Sponsor
- Vitrolife
Multiple Sclerosis
Trichuris Suis Ova (TSO)in Recurrent Remittent Multiple Sclerosis and Clinically Isolated Syndrome
Trichuris suis ova (TSO) is a probiotic treatment based on the hygiene hypothesis, that has proven safe and effective in autoimmune inflammatory bowel disease.
- Trial name
- TRIOMS (NCT01413243)
- Testing
- Trichuris suis ova
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Egg Consumption
Complementary Feeding Project in Ethiopia
The Global Alliance for Improved Nutrition (GAIN), a Swiss-based foundation, implemented a complementary feeding project to improve dietary quality among children 6-59 months of age living in Ethiopia by improving demand and…
- Trial name
- NCT05062382
- Testing
- Complementary feeding intervention
- Where
- Ethiopia
- Volunteers
- 1,132 people, healthy volunteers welcome
- Sponsor
- University of South Carolina