Clinical trials: Oophorectomy
Postoperative Pain, Postoperative Nausea and Vomiting
Analgesic Effect of Preoperative Dexamethasone in Gynecological Laparotomies - a Dose-ranging Study
The objective of the study is to examine the effect of the addition of intravenous dexamethasone 1.5 hours prior to induction of anesthesia on the post-operative opioid consumption, pain scores, fatigue, and recovery in patients…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Fatigue
- Trial name
- NCT01022528
- Testing
- Dexamethasone (0.1 mg/kg), Dexamethasone (0.2 mg/kg), Saline
- Where
- Canada
- Volunteers
- 138 people
- Sponsor
- Women's College Hospital
Menopause, Postmenopausal Bone Loss
Effects of Tibilone on Bone Density, Menopause Symptoms and Breast Density in Women After Prophylactic Oophorectomy
Women undergoing surgical menopause often experience marked menopausal side effects but are reluctant to use estrogen or other female hormones to ease the transition to menopause because of worries that the hormones may increase…
- Conditions
- Menopause, Postmenopausal Bone Loss, Breast Cancer
- Trial name
- NCT00165204
- Testing
- Tibolone
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Dana-Farber Cancer Institute
Stage IV Colon Cancer
Oophorectomy Followed by Chemotherapy Versus Chemotherapy Alone in Colorectal Cancer Patients
This is a prospective phase III trial to define the role of oophorectomy in metastatic colorectal cancer patients with ovarian metastasis.
- Trial name
- NCT01483443
- Testing
- Oophrectomy
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Gachon University Gil Medical Center
Gynecologic Laparoscopic Surgery, Hysterectomy
Impact of Nociceptive-Level (NOL) Intraoperative Guided Analgesia During Gynecological Laparoscopic Surgery Under General Anesthesia
The aim of the present study is to show that the use of the NOL device in addition to the Standard of Care (based on mean arterial blood pressure and heart rate values) to guide the administration of opioids compared to the…
- Conditions
- Gynecologic Laparoscopic Surgery, Hysterectomy, Oophorectomy
- Trial name
- NOLGYN (NCT03776838)
- Testing
- Intravenous Fentanyl guided by SoC+NOL, Intravenous Fentanyl guided by SoC
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Ovarian Carcinoma
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
This clinical trial evaluates how well two surgical procedures (bilateral salpingectomy and bilateral salpingo-oophorectomy) work in reducing the risk of ovarian cancer for individuals with BRCA1 mutations.
- Trial name
- NCT04251052
- Testing
- Bilateral Salpingectomy, Bilateral Salpingectomy with Oophorectomy, Biospecimen Collection
- Where
- 574 sites in United States, Canada and 1 more
- Volunteers
- 1,956 people
- Sponsor
- NRG Oncology
Hysterectomy, Ovariectomy
TDSM- Testosterone Dose Response in Surgically Menopausal Women
TDSM will study the physiology of testosterone in women ages 21-60 who have had surgical menopause (uterus and both ovaries removed).
- Conditions
- Hysterectomy, Ovariectomy, Menopause, Testosterone Deficiency
- Trial name
- NCT00494208
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Breast Cancer, Ovarian Cancer
Decision-making Regarding Prophylactic Mastectomy and Oophorectomy in Women Seeking Genetic Counseling and Testing for BRCA1/2 Mutations
The purpose of this study is to learn more about women's decision to undergo prophylactic surgery. This is removal of healthy organs in order to reduce risk of cancer.
- Trial name
- NCT00579007
- Testing
- telephone interviews
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Memorial Sloan Kettering Cancer Center