Clinical trials: Open Fractures
Open Reduction and Internal Fixation of Extremity Fractures
MICRO Study: Detecting Bacterial Infections Related to Orthopaedic Surgical Implants
A prospective trial conducted at Shock Trauma of patients between 18 years of age and older who have sustained a fracture with metal implanted.
- Trial name
- MICRO (NCT03132246)
- Testing
- Blood draws
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- University of Maryland, Baltimore
Tibial Plateau Fractures
Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau
The investigators are conducting this research study to find better ways of treating pain following knee surgery. There is a standard (accepted) approach, which involves injection of numbing medication into the area around the…
- Trial name
- NCT06639503
- Testing
- Bupivacain
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Chicago
Mandibular Angle Fracture, Surgical Approach &Amp; Incisions
Efficacy of Transoral Versus Transbuccal Technique for Fixation of Mandibular Angle Fracture
The goal of this clinical trial is to learn if transbuccal technique for mandibular angle fracture is better than transoral technique.
- Trial name
- NCT06622642
- Testing
- Transoral technique for mandibular angle fracture reduction, Transbuccal technique for mandibular angle fracture reduction
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Tibia Fracture
Ilizarov Frame or Uni Planar External Fixator in the Cost-conscious Era
Tibial shaft fracture is a common injury worldwide. Their treatment, prognosis, and outcome are determined by the mechanism of injury, presence of communition, soft tissue injury and displacement.
- Trial name
- NCT03936972
- Testing
- ilizarov circular frame and uni-planarexternal fixator
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Fractures, Open, Fractures, Closed
LOQTEQ® Antibacterial Pre-Market Study
aap001 is a randomized, controlled, subject-blinded, multi-center study to show the safety of the LOQTEQ® antibacterial silver-coated system is non-inferior in comparison with the uncoated LOQTEQ® system
- Conditions
- Fractures, Open, Fractures, Closed, Surgical Site Infection, Fracture of Fibula
- Trial name
- NCT05260463
- Testing
- Implantation
- Where
- 13 sites in Germany
- Volunteers
- 203 people
- Sponsor
- aap Implantate AG
Fracture, Trauma
Surgical Treatment Versus Non-surgical Treatment of Ulnar Fractures
The purpose of this study is to determine if surgery using a plate and screws to fix a forearm fracture (ulnar shaft) will improve functional outcome compared to non-operative treatment out to 1 year of follow-up.
- Conditions
- Fracture, Trauma, Ulna Fracture, Orthopedic
- Trial name
- NCT01123447
- Testing
- Open reduction and internal fixation, Closed reduction and short-arm cast
- Where
- 9 sites in Canada, United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Malunion of Fracture of Radius
Evaluating the Utility of Bone Grafts in Open Wedge Corrective Osteotomy and Plate Fixation
INTRODUCTION A variety of bone grafts and substitutes are available for filling bone defects in the distal radius after corrective osteotomy, but the harvesting of bone from the iliac crest is the gold standard as it allows easy…
- Trial name
- WOPPeR (NCT06093763)
- Testing
- Group without bone grafting, Group with bone grafting
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Infection, Wound Healing Problem
Fluid Lavage of Open Wounds (FLOW): Pilot Trial
The purpose of this trial is to investigate whether irrigation solution (soap vs. saline solution), or irrigation pressure (high vs. low) will decrease the rate of infection among patients with open fracture wounds.
- Conditions
- Infection, Wound Healing Problem, Nonunion
- Trial name
- FLOW (NCT01069315)
- Testing
- Type of fluid lavage solution, Type of fluid lavage pressure
- Where
- 9 sites in United States, Canada and 1 more
- Volunteers
- 111 people
- Sponsor
- McMaster University
Lumbar Vertebral Fracture
Percutaneous Screw Fixation vs. Open Fixation in the Treatment of Thoracolumbar Fractures
In this single-center retrospective study, the investigators will include all patients admitted to Parkland Hospital who underwent surgical fixation of thoracolumbar fractures between the years 2000 and 2017.
- Trial name
- PrecScrew (NCT04495400)
- Testing
- Thoracolumbar Fracture Fixation
- Where
- United States
- Volunteers
- 485 people
- Sponsor
- University of Texas Southwestern Medical Center
Major Trauma
Impact of Psychoeducational Video on Adjustment to Open Fracture.
The multi-disciplinary team involved in the care of major trauma patients with open fractures has developed two novel patient information videos.
- Trial name
- NCT04551157
- Testing
- Video Viewing
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Oxford University Hospitals NHS Trust
Lateral Malleolus Fracture, Minimally Invasive Surgical Procedure
Comparison of Patients Who Underwent Open and Minimally Invasive Fixation in Lateral Malleolar Fractures
The aim of this study was to compare the postoperative clinical, functional and radiological results of two different surgical methods, minimally invasive percutaneous plate osteosynthesis method and open reduction-internal…
- Conditions
- Lateral Malleolus Fracture, Minimally Invasive Surgical Procedure, Postoperative Pain, Patient Discharge
- Trial name
- NCT06753656
- Testing
- Open Surgery, Minimally Invasive Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Giresun University
Elbow Fracture, Range of Motion
Does Early Elbow Motion Improve Patient Outcomes After Surgically Treated Elbow Fractures?
The purpose of this study is to compare the safety and efficacy, defined as improved range of motion and functional outcome scores, of early elbow motion in the early (immediately post-op) and late postoperative periods (2 week…
- Conditions
- Elbow Fracture, Range of Motion, Immobilization
- Trial name
- NCT05980312
- Testing
- Splint Immobilization, Early Motion
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Rib Fractures, Analgesia
Lidocaine Spray for Pain Control in Rib Fractures
In this study, we aimed to compare the analgesic efficacy of lidocaine spray with tramadol hydrochloride and fentanyl citrate in rib fractures.
- Trial name
- NCT05500677
- Testing
- Lidocaine topical
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ankara City Hospital Bilkent
Femoral Neck Fractures
Open Reduction in Femoral Neck Fractures
Outcomes of open reduction and internal fixation of femoral neck fractures using dynamic hip screw versus cannulated screws combined with medial buttress plate.
- Trial name
- OR FNFS (NCT06872970)
- Testing
- Open reduction of femoral neck fractures and internal fixation by dynamic hip screws, Open reduction of femoral neck fractures using watson jones or smith peterson approachand internal fixation by cannulated screws and medial buttress plate
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Samer youssef mansour meglaa
Lateral Condyle Humerus Fracture in Children
Kirschner Wires Fixation Versus Cannulated Screws Internal Fixation for Displaced Lateral Condyle Humeral Fracture in Children
Lateral condyle fracture of the distal humerus is the second most common injury around the elbow and accounts for 20% of all the elbow fractures in children.The average age for the fracture involving the lateral condyle is around…
- Trial name
- NCT05409053
- Testing
- open reduction, Closed reduction, Conservative management
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Fracture, Fractures, Bone
FastFrame Knee Spanning and Damage Control Kit PMCF
The purpose of this prospective study is to confirm safety and performance of the FastFrame External Fixation System and corresponding instrumentation.
- Conditions
- Fracture, Fractures, Bone, Fractures, Closed, Fractures, Open
- Trial name
- NCT04730739
- Testing
- FastFrame External Fixation System - Knee Spanning or Damage Control Kit
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Zimmer Biomet
Jones Syndrome, Metatarsal Bone Fractures
Short Leg Walking Plaster Cast Versus Walking Foot Cast for Jones Fracture
This study is an open-label, randomized controlled trial comparing the effectiveness of two plaster cast methods-Short Leg Walking Plaster Cast and Walking Foot Plaster Cast-for treating Jones fractures, a common fracture at the…
- Trial name
- NCT06687668
- Testing
- Short Leg Walking Plaster Cast, Walking Foot Plaster Cast
- Where
- Pakistan
- Volunteers
- 122 people
- Sponsor
- Khyber Medical University Peshawar
Hip Fracture, Geriatrics
Clinical Efficacy of Exoskeleton Robot-Assisted Rehabilitation on Lower Limb Functional Recovery in Elderly Patients With Hip Fracture
With the intensification of population aging, hip fracture, as a common bone disease, is seeing an increasing incidence rate among the elderly population.
- Conditions
- Hip Fracture, Geriatrics, Lower Extremity Dysfunction, Postoperative Rehabilitation
- Trial name
- NCT07323147
- Testing
- Exoskeleton, Conventional rehabilitation program
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Hai bao
Open Pilon Fractures
Open Pilon With FIBERGRAFT AERIDYAN Matrix Bioactive Glass
Open pilon fractures are challenging problems to manage. Infection rates vary from 6-30% and metaphyseal nonunion varies from 7-20%.
- Trial name
- NCT07227493
- Testing
- Fibergraft Aeridyan Matrix
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Missouri-Columbia
Postmenopausal Osteoporosis
Efficacy & Safety of Abaloparatide-Solid Microstructured Transdermal System in Postmenopausal Women With Osteoporosis
A 12-month study to compare the efficacy and safety of abaloparatide-solid microstructured transdermal system (sMTS) with abaloparatide-subcutaneous (SC).
- Trial name
- NCT04064411
- Testing
- abaloparatide, abaloparatide solid microstructured transdermal system
- Where
- 97 sites in United States, Denmark and 3 more
- Volunteers
- 511 people
- Sponsor
- Radius Health, Inc.