Clinical trials: Open Fractures
Tibial Fractures
Safety Study of Treatment of Leg Fractures
This study evaluates the safety of the EVOS SMALL Plating system in patients who have a fracture of the tibia requiring surgery.
- Trial name
- EVOS SMALL (NCT03881241)
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Smith & Nephew, Inc.
Lateral Malleolus Fracture, Minimally Invasive Surgical Procedure
Comparison of Patients Who Underwent Open and Minimally Invasive Fixation in Lateral Malleolar Fractures
The aim of this study was to compare the postoperative clinical, functional and radiological results of two different surgical methods, minimally invasive percutaneous plate osteosynthesis method and open reduction-internal…
- Conditions
- Lateral Malleolus Fracture, Minimally Invasive Surgical Procedure, Postoperative Pain, Patient Discharge
- Trial name
- NCT06753656
- Testing
- Open Surgery, Minimally Invasive Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Giresun University
Proximal Humeral Fracture, Dislocation
Proximal Humerus Fracture Dislocation Direction and Avascular Necrosis
The purpose of the study is to see if there is a connection between a proximal humerus fracture dislocation direction and the likelihood of developing avascular necrosis.
- Conditions
- Proximal Humeral Fracture, Dislocation, Dislocation Shoulder, Avascular Necrosis
- Trial name
- PHF-D (NCT05735561)
- Testing
- X-Ray
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Fraser Orthopaedic Research Society
Distal Radius Fracture
Postsurgical Bupivacaine Extended-release Liposome Injection for Open-reduction Internal Distal Radius Fixation.
For patients undergoing open-reduction internal-fixaton (ORIF) of isolated distal radius fractures, administration of 66.5 mg of liposomal bupivacaine to operative field may decrease the need for post-operative narcotic pain…
- Trial name
- NCT02515851
- Testing
- Exparel
- Volunteers
- 30 people
- Sponsor
- University of Louisville
Thoracolumbar Spine Trauma
Treatment of Thoracolumbar Spine Fractures: Percutaneously Placed Pedicle Screws Versus Open Treatment
In patients presenting with Type A and Type B1, B2 thoracolumbar fractures, there is a lack of evidence demonstrating similar outcomes between patients treated with percutaneous pedicle screws and those treated openly.
- Trial name
- NCT02146729
- Testing
- Percutaneous Pedicle Screw Fixation, Open Treatment
- Where
- United States
- Sponsor
- Daniel Altman
Opioid Free Anesthesia, Stress Response
The Impact Opioid Free Anesthesia on Postoperative Pain Intensity and Stress Response After Open Gynecology Surgery
This study compared impact of multimodal balancing anesthesia vs opioid free anesthesia on postoperative pain intensity and stress response after open gynecology surgery.
- Conditions
- Opioid Free Anesthesia, Stress Response, Postoperative Pain
- Trial name
- NCT07138053
- Testing
- OFA group
- Where
- Bosnia and Herzegovina
- Volunteers
- 70 people
- Sponsor
- Cantonal Hospital Zenica
Open tíbia Fracture
Management of Open Fracture Tibia in Teenagers
The aim of this study is to study the incidence of open tibial fractures in early teenagers and evaluate the management outcomes
- Trial name
- NCT06288139
- Volunteers
- 100 people
- Sponsor
- Assiut University
Osteo Arthritis Shoulders, Osteonecrosis
Exactech Shoulder Post Market Clinical Follow-up Study
The objective of this study is to collect and evaluate long-term clinical and radiographic outcomes data in order to better understand the safety and performance of the shoulder arthroplasty over time.
- Conditions
- Osteo Arthritis Shoulders, Osteonecrosis, Rotator Cuff Tears, Rotator Cuff Tear Arthropathy
- Trial name
- NCT05603728
- Where
- 40 sites in United States, Canada and 4 more
- Volunteers
- 20,000 people
- Sponsor
- Exactech
Primary Osteoarthritis, Secondary Osteoarthritis
Prospective Study for the Evaluation of the Cementless Anatomic Femoral Stem Minimax -Launay
This is a post-marketing surveillance on MiniMAX Stem
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Traumatic Arthritis, Rheumatoid Arthritis
- Trial name
- NCT06012656
- Testing
- MiniMAX
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Medacta International SA
Ankle Fracture
Liposomal Bupivacaine With Bupivacaine in Ankle Fracture Open Reduction Internal Fixation (ORIF)
This study is a randomized controlled trial assessing pain control in ankle fractures repaired with open reduction and internal fixation.
- Trial name
- NCT02480621
- Testing
- Liposomal Bupivacaine with Bupivacaine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Jamaica Hospital Medical Center
Osteoporosis
The Study of the Early Administration of Alendronate on Prevention of Bone Loss After Hip Fracture.
To determine whether administration of Alendronate early is more effective than late in the prevention of osteoporosis following a hip fracture
- Trial name
- NCT00346190
- Testing
- Alendronate
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Jones Syndrome, Metatarsal Bone Fractures
Short Leg Walking Plaster Cast Versus Walking Foot Cast for Jones Fracture
This study is an open-label, randomized controlled trial comparing the effectiveness of two plaster cast methods-Short Leg Walking Plaster Cast and Walking Foot Plaster Cast-for treating Jones fractures, a common fracture at the…
- Trial name
- NCT06687668
- Testing
- Short Leg Walking Plaster Cast, Walking Foot Plaster Cast
- Where
- Pakistan
- Volunteers
- 122 people
- Sponsor
- Khyber Medical University Peshawar
Proximal Humeral Fracture
Proximal Humerus Fractures: A Retrospective Analysis
The purpose of this study is to evaluate preoperative objective measurements of patients with a proximal humerus fracture and operative objective measurements to determine if there is any effect to postoperative outcomes.
- Trial name
- PHFx (NCT03637608)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- The Orthopaedic Research & Innovation Foundation
Zygomatic Arch Reduction
Reduction of Zygomatic Arch in Zygomaticomaxillary Fractures
To compare between ultrasound guided closed reduction and open reduction of zygomatic arch in cases of zygomaticomaxillary fracture. To evaluate the role of intra-operative ultrasound during zygomatic arch reduction.
- Trial name
- NCT04218058
- Testing
- reduction of zygomatic arch in zygomaticomaxillary complex fracture
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Ankle Fractures
Open Reduction Syndesmosis Tightrope Versus Screw Fixation
Tibia-fibular syndesmosis injury occurs in a significant proportion of ankle injuries and is assumed to disrupt the syndesmotic ligaments.
- Trial name
- NCT02199249
- Testing
- Open reduction Tightrope fixation, open reduction screw fixation
- Where
- Canada
- Volunteers
- 103 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lower Extremity Fracture
Antibiotic Use & Open Fracture of the Lower Extremity
It is important to recognize the potential for renal injury and be cognizant of this during the management of complex trauma patients.
- Trial name
- NCT05267977
- Testing
- Cephalosporin 1St Generation, Aminoglycosides
- Sponsor
- Methodist Health System
Major Trauma
Impact of Psychoeducational Video on Adjustment to Open Fracture.
The multi-disciplinary team involved in the care of major trauma patients with open fractures has developed two novel patient information videos.
- Trial name
- NCT04551157
- Testing
- Video Viewing
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Oxford University Hospitals NHS Trust
Aseptic Loosening, Osteolysis
Post-Market Study of the Modular Revision Hip System
The purpose of this study is to examine the short term efficacy of the MRH system as well as determine if operating room time is decreased using this simple, two-tray system.
- Conditions
- Aseptic Loosening, Osteolysis, Traumatic Fracture, Failed Total Hip Implant
- Trial name
- MRHS (NCT01464645)
- Testing
- Modular Revision Hip System
- Where
- 6 sites in United States
- Volunteers
- 16 people
- Sponsor
- Encore Medical, L.P.
WALANT, Radius Fracture Distal
Prospective Observational Study Comparing GA and WALANT in Distal Radius Fracture Plating Surgery
The wide-awake local anesthesia no tourniquet (WALANT) has been widely used in the field of hand surgery in recent years. This surgical method has progressed to open reduction and internal fixation of distal radial fracture and…
- Trial name
- NCT04549441
- Testing
- Distal radius fracture plating surgery
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Medical University
Duchenne Muscular Dystrophy
A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD)
The purpose of this study is to assess the efficacy, safety, pharmacokinetics (PK) and pharmacodynamics (PD) of satralizumab, a humanized anti-interleukin-6 receptor (aIL-6R) monoclonal antibody, in ambulatory and non-ambulatory…
- Trial name
- SHIELD DMD (NCT06450639)
- Testing
- Satralizumab
- Where
- 18 sites in United States, Denmark and 4 more
- Volunteers
- 30 people
- Sponsor
- Hoffmann-La Roche