Clinical trials: Open Heart Surgery Patients
Patient Depression, Anxiety, Stress and Pain
The Effect of Listening to Holy Quran Recital on Depression, Anxiety and Stress Post CABG
Coronary artery bypass graft (CABG) is one of the most common surgical treatments for coronary artery disease. CABG has many beneficial outcomes for patients.
- Trial name
- NCT05419544
- Testing
- Holy Quran Recital effect
- Where
- 2 sites in Jordan
- Volunteers
- 128 people
- Sponsor
- Applied Science Private University
Cardiac Surgery, Adult
Erector Spinae Plane Block and Pain Management in Cardiac Surgery
Evaluation of the benefit effects of Peri-Operative analgesia by Continuous Bilateral Erector Spinae Plane block(ESP) for Open Cardiac Surgery: A case series prospective study with a comparison a retrospective case series (Before…
- Trial name
- ESPCATHEART (NCT03541837)
- Testing
- Ropivacaine
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Vinmec Healthcare System
Undergoing Open-Heart Surgery
Opioids Continue to Play a Primary Role in the Management of Perioperative Pain Due to Opioid-Free Anesthesia in Open Heart Surgery.
Due to their superior efficacy in analgesia, opioids continue to play a primary role in the control of intraoperative and postoperative pain.
- Trial name
- Opioid-Free (NCT06683911)
- Testing
- non Opioids, Opioid
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Ankara City Hospital Bilkent
Anemia, Iron Deficiency
Nutritional Optimization in Anemic Patients Scheduled for Elective Open-Heart Surgery
1. To test the effect and feasibility of culturally relevant SNP program in Anaemic patients scheduled for elective open-heart surgery versus those getting usual preoperative care in a public sector hospital. 2.
- Trial name
- Prehab_Nutri (NCT07801469)
- Testing
- Immune Modulating Formula, Whey Protein, Multivitamins and Iron Supplements
- Volunteers
- 140 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Dilated Cardiomyopathy
Safety and Feasibility of Algisyl-LVR™ as a Method of Left Ventricular Restoration in Patients With DCM Undergoing Open-heart Surgery
This is a pilot study to evaluate the feasibility and safety of the Algisyl-LVR™ device. The purpose of this study is to investigate Algisyl-LVR™ employed as a method of left ventricular restoration in patients with dilated…
- Trial name
- NCT00847964
- Testing
- Algisyl-LVR
- Where
- 3 sites in Germany, Poland
- Volunteers
- 11 people
- Sponsor
- LoneStar Heart, Inc.
Open Heart Surgery Patients
Patient Education by Mobile Application
Cardiovascular diseases are among the important health problems that cause mortality and morbidity both in our country and in the World (Sidar vd 2013).
- Trial name
- NCT05094063
- Testing
- patient education by mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Betul Zeynep Yildiz
Delirium - Postoperative, Cardiac Surgery
Lemborexant to Prevent Post-operative Delirium in Cardiac Surgery Patients
Post-operative delirium is a common complication following cardiac surgery and is associated with increased 1 year mortality. Currently there are no drug therapies to prevent delirium.
- Conditions
- Delirium - Postoperative, Cardiac Surgery, Cardiac Surgery Subjects, Orexin Antagonist
- Trial name
- PROTEX (NCT06648681)
- Testing
- Lemborexant 5 mg
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Diabetes Mellitus
Transitioning Open Heart Surgery Patients From Insulin Infusions to Detemir
In this study we will determine the proper method for transitioning patients from a continuous insulin infusion to periodic injections of a newer long-acting insulin called detemir (Levemir).
- Trial name
- NCT00717288
- Testing
- Detemir
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Ohio State University
Sleep Quality, Intensive Care (ICU)
Predictors of Sleep Quality in Patients Undergoing Open-Heart Surgery
Sleep quality is a complex and multidimensional phenomenon shaped by the interaction of patient characteristics, symptom burden, and environmental factors specific to the intensive care unit environment.
- Conditions
- Sleep Quality, Intensive Care (ICU), Nursing Care
- Trial name
- NCT07755280
- Where
- Turkey (Türkiye)
- Volunteers
- 157 people
- Sponsor
- Aydin Adnan Menderes University
Congenital Heart Disease in Children
BAX602 in Preventing the Adhesion Around Great Cardiac Vessels in Pediatric Patients With Congenital Heart Disease Undergoing Re-do Open Heart Surgery (Japan Trial)
Congenital heart disease occurs in about 1% of live births and can range from (1) naturally curable conditions that require no treatment to (2) conditions that require multiple immediate operations or refractory severe…
- Trial name
- NCT05647161
- Testing
- BAX602, No Intervention
- Where
- 6 sites in Japan
- Volunteers
- 34 people
- Sponsor
- Baxter Healthcare Corporation
Cardiac Rehabilitation
Comparison of Open Heart Surgery Patients With Forward Head Posture With and Without Perioperative Therapeutic Exercise
Comparison of open heart surgery patients with forward head posture with and without perioperative therapeutic exercise on craniovertebral angle, pulmonary function, balance and quality of life
- Trial name
- NCT05967780
- Testing
- Group A: Patients with FHP receiving standard cardiac rehabilitation, Group B: Patients with FHP receiving standard cardiac rehabilitation + therapeutic exercises, Group C: Patients without FHP receiving standard cardiac rehabilitation
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Health Education Research Foundation (HERF)
Right Heart Failure, Open-heart Surgery
Levosimendan in Patients With Impaired Right Ventricular Function Undergoing Cardiac Surgery
Perioperative right ventricular (RV) function is an important determinant of postoperative outcomes after cardiac surgery. Perioperative RV dysfunction increases the need for perioperative inotropic support, prolongs intensive…
- Trial name
- NCT05063370
- Testing
- Levosimendan, Standard Care
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Surgery, Cardiac Disease
Self-Affirmation for Managing Anxiety and Perceived Discomfort in Open-Heart Surgery
This study adopted a randomized controlled pretest-posttest follow-up research design. The study was conducted at a public training and research hospital (Istanbul, Turkey) specialized in thoracic and cardiovascular surgery.
- Trial name
- NCT05487430
- Testing
- Positive Self-Affirmation
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- University of Vic - Central University of Catalonia
CABG-patients, Saphenectomy
Clinical Impact of Surgical Wound Morbidity According to the Type of Saphenous Vein Harvesting Technique (Endoscopic vs. Open) in Patients Undergoing Myocardial Revascularization Surgery
The goal of this clinical trial is to compare two different techniques: endoscopic saphenous vein harvesting versus conventional open harvesting in patients undergoing coronary artery bypass grafting, either alone or in…
- Conditions
- CABG-patients, Saphenectomy, Endoscopic Surgery, Wound Complications
- Trial name
- EndOSiC (NCT07002658)
- Testing
- Harvesting of the saphenous vein graft
- Where
- Spain
- Volunteers
- 356 people
- Sponsor
- Hospital San Carlos, Madrid
Open Heart Surgery, Preconditioning
Effect of Cardiac Preconditioning Upon the Inotrope Score
preconditioning of no debate has a valuable effect upon myocardial protection . pre-cardiopulmonary bypass pre-conditioning , suspected to have a role upon postoperative inotropic support
- Trial name
- NCT03105089
- Testing
- ischemic preconditioning
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Sternotomy Closure,Open Heart Surgery
Comparison Between Interlocking Multi-twisted Wires and Eight Figure of Sternum Closure
Comparison between interlocking multi-twisted wires and Eight figure of sternum closure post open heart surgery in egptian patients
- Trial name
- NCT03343990
- Testing
- Interlocking multi-twisted wires in sternal closure, Eight Figure techniqe in sternal closure
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ischemic Heart Disease
The Danish On-pump, Off-pump Randomization Study (DOORS)
Background: Coronary artery bypass grafting (CABG) can be performed either with or without the use of cardiopulmonary bypass (CPB) to obtain myocardial re-vascularisation.
- Trial name
- NCT00123981
- Testing
- Off-Pump Coronary Artery Bypass Grafting
- Where
- Denmark
- Volunteers
- 900 people
- Sponsor
- Kim Houlind
Heart; Surgery, Heart, Functional Disturbance as Result
The Use of Cooling Helmet for Neuroprotection Management in Open Heart Surgery
To know the relationship between the use of cooling helmet with the changes of NSE level and postoperative delirium event in open heart surgery
- Trial name
- NCT05264766
- Testing
- Cooling helmet on, Cooling helmet off
- Where
- Indonesia
- Volunteers
- 26 people
- Sponsor
- Universitas Indonesia
Electrolyte Imbalances, Acute Kidney Injury
Investigation of Fluid- and Electrolyte Balance in Post Cardiac-surgery Patients
Critically ill patients need intravenous fluid therapy in order to correct or prevent problems with their fluid and/or electrolyte status and for renal protection.
- Trial name
- Clinibil (NCT02914782)
- Testing
- Observational Study
- Where
- Austria
- Volunteers
- 176 people
- Sponsor
- Medical University of Graz
Peripheral Perfusion
Radial Artery Cannulation and Perfusion Index
This study aims to investigate if radial artery cannulation of the dominant hand affects its peripheral perfusion during cardiac surgery using cardiopulmonary bypass.
- Trial name
- NCT03845361
- Testing
- Radial artery cannulation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University