Clinical trials: Open Nephrectomy
Erector Spinae Plane Block, Thoracic Epidural Analgesia
Ultrasound-guided Continuous Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Open Nephrectomy
There are different case studies about the use of erector spinae block (ESPB ) in nephrectomy, but there are no enough randomized controlled studies about it until now so it will be one of the earliest studies that investigate…
- Conditions
- Erector Spinae Plane Block, Thoracic Epidural Analgesia, Nephrectomy
- Trial name
- NCT04947644
- Testing
- Thoracic epidural analgesia, Ultrasound guided continuous erector spinae plane block
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- National Cancer Institute, Egypt
External Oblique Intercostal Plane Block, Transversus Abdominis Plane Block
External Oblique Intercostal Plane Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Adult Patients Undergoing Open Nephrectomy
The aim of this study is to compare external oblique intercostal plane (EOIP) block and ultrasound guided transversus abdominis plane (TAP) Block for postoperative analgesia in adult patients undergoing open nephrectomy.
- Conditions
- External Oblique Intercostal Plane Block, Transversus Abdominis Plane Block, Postoperative Analgesia, Nephrectomy
- Trial name
- NCT06452238
- Testing
- External Oblique Intercostal Plane Block, Transversus Abdominis Plane Block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Kidney Transplantation
Donor Recipient Kidney Function Following Open Surgical vs. Laparoscopic Kidney Donation
This study will evaluate the differences between open surgical kidney donation and laparoscopic kidney donation on kidney donors and recipients.
- Trial name
- NCT00100516
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
the Patients With Partial Nephrectomy
Assessment of Acute Renal Injury During Partial Nephrectomy Using Neutrophil Gelatinase-associated Lipocalin (NGAL): Prospective Comparative Study Between Open, Video-assisted Minilaparotomy, Laparoscopic, and Robotic-assisted Laparoscopic Surgery
Urinary Neutrophil gelatinase associated lipocalin (NGAL) has been recently reported to be related with the degree of acute kidney injury.
- Trial name
- NCT01891032
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Yonsei University
Renal Tumor
Cost-effectivness of Robot-assisted Surgery Compared to Open Surgery for Partial Nephrectomy in Context of Renal Tumor
This study aim to analyze cost-effectiveness of robot-assisted surgery compared to open surgery for partial nephrectomy in the context of renal tumor.
- Trial name
- écoREIN (NCT05089006)
- Testing
- Partial nephrectomy with robot-assisted and open surgery
- Volunteers
- 400 people
- Sponsor
- Central Hospital, Nancy, France
Kidney Transplantation
Medical Economic Evaluation and of Quality of Life of the Kidney Living Donors.
The main objective of this multicentre study is to conduct the evaluation of cost-efficiency of various techniques of kidney taking with regard the quality of life of the kidney living donors.
- Trial name
- DOVIREIN (NCT02830568)
- Testing
- open donor nephrectomy, standard and hand-assisted laparoscopic donor nephrectomy, laparoscopic robotic-assisted nephrectomy
- Where
- 24 sites in France
- Volunteers
- 268 people
- Sponsor
- Central Hospital, Nancy, France
Post Operative Pain
Ultrasound Guided Rhomboid Intercostal Subserratus Plane Block vs Erector Spinae Plane Block in Open Nephrectomy
Our aim is to measure the efficacy of rhomboid intercostal subserratus plane block and erector spinae plane block in patients undergoing open nephrectomy
- Trial name
- NCT05822011
- Testing
- Rhomboid intercostal subserratus plane block, Erector spinae plane block
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Renal Cell Carcinoma (Kidney Cancer)
Radical Nephrectomy With vs Without Template Lymph Node Dissection in High-Risk Renal Cell Carcinoma (T-LND RCC)
The goal of this clinical trial is to learn if a more thorough lymph node removal surgery, called "Template Lymph Node Dissection," can help prevent cancer from returning and help patients live longer, compared to removing only a…
- Trial name
- RECLND (NCT07321197)
- Testing
- Template Lymph Node Dissection, Selective Lymph Node Resection
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Tianjin Medical University Second Hospital
Nephrectomy, Lung Diseases
Thoracic Spinal Versus Epidural Anesthesia for Nephrectomy in Obstructive/Restrictive Lung Disease Patients
Patients with respiratory disease have an increased risk of developing complications perioperatively. The use of regional anesthesia decreases this risk with better postoperative outcome.
- Conditions
- Nephrectomy, Lung Diseases, Anesthesia
- Trial name
- NCT03324490
- Testing
- Thoracic Spinal Anesthesia, Thoracic Epidural Anesthesia, Bupivacaine 0.5% (hyperbaric)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Nazmy Edward Seif
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Robotic vs Open Nephrectomy for ADPKD
The goal of this observational prospective cohort study is to evaluate the feasibility, safety, and postoperative outcomes of robotic-assisted unilateral native nephrectomy using the Medtronic Hugo™ RAS system compared with the…
- Trial name
- ADPKDR-O (NCT07355114)
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- University of Bologna
Transversus Abdominis Plane Block, External Oblique Intercostal Plane Block
Transversus Abdominis Plane Block Versus External Oblique Intercostal Plane Block for Postoperative Analgesia in Pediatrics Undergoing Open Nephrectomy
The aim of this study is to compare the ultrasound guided TAP Block and EOIP block for postoperative analgesia in pediatrics undergoing open nephrectomy.
- Conditions
- Transversus Abdominis Plane Block, External Oblique Intercostal Plane Block, Postoperative Analgesia, Pediatrics
- Trial name
- NCT06452225
- Testing
- External Oblique Intercostal Plane Block, Transversus Abdominis Plane Block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Bilateral, Ultrasound
Bilateral Ultrasound Guided Intramuscular Quadratus Lumborum Plane Block Versus Bilateral Lateral Quadratus Lumborum Plane Block in Controlling Postoperative Pain in Cancer Patients Undergoing Open Nephrectomy
This study aims to evaluate the efficacy of bilateral ultrasound-guided intramuscular quadratus lumborum plane block (QL4) versus bilateral lateral quadratus lumborum plane block (QL1) in controlling postoperative pain in cancer…
- Conditions
- Bilateral, Ultrasound, Intramuscular Quadratus Lumborum Plane Block, Lateral Quadratus Lumborum Plane Block
- Trial name
- NCT06889987
- Testing
- Intramuscular quadratus lumborum block, Lateral quadratus lumborum block, General anesthesia
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Pain, Partial Nephrectomy
Rib Removal and Pain in Partial Nephrectomy
In this study, the effect of rib removal on postoperative pain in kidney cancer patients undergoing retroperitoneal open partial nephrectomy with flank incision was investigated.
- Conditions
- Pain, Partial Nephrectomy, Kidney Cancer
- Trial name
- NCT06543095
- Testing
- Pain level
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- TC Erciyes University
Kidney Tumors, CKD
Kidney-protective Intervention With Salt Substitute After Kidney Tumor Surgery
This clinical trial is an open-label, randomized controlled study designed to evaluate the efficacyand safety of salt substitutes in protecting renal function after kidney tumor surgery, aiming toprovide dietary renal protection…
- Conditions
- Kidney Tumors, CKD, Salt Substitute, Nephrectomy
- Trial name
- NCT07062952
- Testing
- Salt substitute
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Jinling Hospital, China
Postoperative Delirium (POD) After Nephrectomy
A Prospective Comparative Clinical Trial of Postoperative Delirium Incidence in Open Versus Laparoscopic Nephrectomy
A prospective comparative clinical trial of postoperative delirium incidence in open versus laparoscopic nephrectomy
- Trial name
- NCT07892898
- Testing
- Open Nephrectomy, Laparoscopic Nephrectomy
- Where
- Egypt
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Wilms Tumor, Renal Cancer
Nephrogreen. Appearances of Exvivo Renal Tumours Under Near-infrared
Indocyanine Green (ICG) is a dye which fluoresces under near-infrared (NIR) light. It has been used for several applications in adult surgery.
- Trial name
- Nephrogreen (NCT05735977)
- Testing
- Indocyanine Green (ICG)
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Birmingham Women's and Children's NHS Foundation Trust
Renal Cell Carcinoma
The Intrathecal Morphine for Nephrectomy
To evaluate the efficacy and the safety of the intrathecal morphine injection in the open nephrectomy.
- Trial name
- EMPON (NCT01997788)
- Testing
- The intrathecal morphine injection, The intravenous patient-controlled analgesia, Demerol on demand
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Seoul National University Hospital
Nonfunctioning Kidney, Renal Cell Carcinoma (RCC)
Laparoscopic Versus Open Nephrectomy : Clinical Effectivness and Cost Analysis
To evaluate and compare clinical effectiveness (operative time, blood loss, hospital stay, complications and etc) and cost analysis' between laparoscopic nephrectomy and open nephrectomy .
- Trial name
- NCT07461090
- Testing
- open or laparoscopic nephrectomy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Pentafecta, Laparoscopic
Current Role of Pentafecta Outcomes in Open and Laparoscopic Partial Nephrectomy for Localized Renal Tumors
This study aimed to identify predictive factors associated with the achievement of pentafecta outcomes following partial nephrectomy.
- Conditions
- Pentafecta, Laparoscopic, Partial Nephrectomy, Renal Tumors
- Trial name
- NCT06969131
- Testing
- Open Partial Nephrectomy, Laparoscopic Partial Nephrectomy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- South Valley University
Carcinoma, Adenocarcinoma
Safety and Efficacy of Bevacizumab Plus RAD001 Versus Interferon Alfa-2a and Bevacizumab for the First-line Treatment in Adult Patients With Kidney Cancer
To estimate the difference in efficacy and safety of bevacizumab and RAD001 compared to bevacizumab and interferon alfa-2a for first-line treatment of patients with metastatic carcinoma of the kidney.
- Conditions
- Carcinoma, Adenocarcinoma, Renal Cell, Nephroid Carcinoma
- Trial name
- NCT00719264
- Testing
- RAD001(everolimus), interferon alfa-2a, bevacizumab
- Where
- 109 sites in United States, Belgium and 19 more
- Volunteers
- 365 people
- Sponsor
- Novartis Pharmaceuticals