Clinical trials: Operable Breast Neoplasms, open to volunteers
Breast Cancer, Cancer of Breast
Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score
Multiple neoadjuvant endocrine trials demonstrate that women with good prognosis tumors can be identified. These trials have also demonstrated that there are not adverse effects on overall outcome if women are treated with…
- Conditions
- Breast Cancer, Cancer of Breast, Breast Neoplasms, Cancer of the Breast
- Trial name
- NCT02476786
- Testing
- FACT-B, Goserelin, Anastrozole
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Breast Cancer, Operable Breast Cancer
EXpander-based Versus Direct to Implant PRE-pectoral Breast Reconstruction: a Comparative Analysis of Surgical Outcomes
Recent advances in breast surgery, together with the increasing adoption of conservative surgical approaches, have renewed interest in pre-pectoral implant-based breast reconstruction.
- Trial name
- EXPRESSO (NCT07593651)
- Volunteers
- 276 people
- Sponsor
- IRCCS San Raffaele
Breast Cancer, Molecular Pathway Deregulation
Study of Molecular Characterisation of Early Operable Primary Breast Cancer in Pakistani Population
This study is looking at the biological characteristics of early operable primary breast cancer in Pakistani Population by using IHC
- Conditions
- Breast Cancer, Molecular Pathway Deregulation, Treatment
- Trial name
- BrCa (NCT06830590)
- Testing
- Molecular characterisation
- Where
- Pakistan
- Volunteers
- 300 people
- Sponsor
- Liaquat University of Medical & Health Sciences
HER2-positive Breast Cancer
Markers to Evaluate the Efficacy of PH-based Regimen as a Neoadjuvant Therapy for Operable HER2 Positive Breast Cancer
This study is to explore the markers in early prediction of the efficacy of pre-operative pertuzumab plus trastuzumab (PH) combined with chemotherapy for early stage or locally advanced human epidermal growth factor receptor-2…
- Trial name
- PHC-BC (NCT04281641)
- Testing
- TCHP
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Fudan University
Breast Cancer
TMEM-MRI: A Pilot Feasibility Study of MRI for Imaging of TMEM in Patients With Operable Breast Cancer
The aim of this study is to assess feasibility of a new imaging technology in the management of breast cancer - Tumor Microenvironment of Metastasis - Magnetic Resonance imaging (TMEM-MRI).
- Trial name
- TMEM-MRI (NCT03694756)
- Testing
- TMEM-MRI, FNA
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Montefiore Medical Center
TNBC - Triple-Negative Breast Cancer
A Multi-center, Randomized, Open-label, Phase III Study Comparing PD-1 Inhibitor Combined With Antivascular Therapy and Anthracycline/Taxane-based Adjuvant Chemotherapy Versus Anthracycline/Taxane-based Adjuvant Chemotherapy Alone in Patients With Operable Triple-negative Breast Cancer
This review will evaluate the efficacy and safety of SHR1210 (Camrelizumab) and antivascular drug(Famitinib) in combination with anthracyclines/taxane-based adjuvant chemotherapy (carrelizumab + FAM + EC-P) compared with…
- Trial name
- NCT05862064
- Testing
- epirubicin,cyclophosphamide,paclitaxel,Carrelizumab, epirubicin,cyclophosphamide,paclitaxel
- Where
- China
- Volunteers
- 606 people
- Sponsor
- Fudan University
Breast Cancer Early Stage Breast Cancer (Stage 1-3), HER2
A Composite Assay for HER2-positive Early-stage Breast Cancer Management
The goal of this observational study is to assess the prognostic value of a genomic classifier (S18) and its refined version (S*) in women with early-stage HER2-positive breast cancer.
- Trial name
- HERCard (NCT06762977)
- Where
- 2 sites in Italy
- Volunteers
- 180 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Ovarian Carcinoma, Breast Carcinoma
Prospective Study of Immune Alterations in Operable Breast and Ovarian Carcinoma
GYNECO-IMM\&Co is a prospective clinical and biological cohort ; this study aims to identify immune surveillance and escape mechanisms and also predictive biomarkers for survival patients who suffer from ovarian and breast…
- Trial name
- GYNECO-IMM&CO (NCT04562623)
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Centre Leon Berard
Triple Negative Breast Cancer, Vitamin D Deficiency
Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients
A two arm pilot study investigating the rate of pathologic complete response in patients with vitamin D deficiency and triple negative breast cancer undergoing standard neoadjuvant chemotherapy + vitamin D supplementation…
- Conditions
- Triple Negative Breast Cancer, Vitamin D Deficiency, Invasive Breast Cancer
- Trial name
- NCT04677816
- Testing
- Standard of Care Neoadjuvant Chemotherapy (NAC), Vitamin D3, Drug Diary
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences