Clinical trials: Operation
Nasal Polyps, Chronic Sinusitis
Wound Healing After Endoscopic Sinus Surgery
This study aims to determine the effect of Thymoquinone (0.5%) and olive oil ointment on Wound healing after Endoscopic sinus surgery.
- Trial name
- NCT06070311
- Testing
- Thymoquinone (0.5%) and Olive oil ointment
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Congenital Heart Diseases
Ulinastatin Injection in in Pediatric Patients Undergoing Open Heart Surgery
1. Explore the efficacy of Ulinastatin use in improving post-operative pulmonary insufficiency and safety in pediatric patients undergoing scheduled CPB open heart surgery to treat Complex Congenital Heart Disease 2.
- Trial name
- NCT02527811
- Testing
- Ulinastatin
- Where
- 5 sites in China
- Volunteers
- 450 people
- Sponsor
- Techpool Bio-Pharma Co., Ltd.
Total Hip Surgery, Pericapsular Nerve
PENG vs. QLB vs. Lumbar ESPB in Total Hip Surgery
The aim of this study is to compare between Pericapsular Nerve Group Block, Erector Spinae Plane Block and Quadratus Lumborum Block for managing acute postoperative pain in patients undergoing total hip surgeries under spinal…
- Conditions
- Total Hip Surgery, Pericapsular Nerve, Quadratus Lumborum, ESPB
- Trial name
- NCT05600244
- Testing
- PENG block Technique, Lumbar ESPB Technique, Transmuscular QLB-t block Technique
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Pulmonary Function
Influence of Tidal Volume on Postoperative Pulmonary Function
Lung function impairment is common after abdominal surgery. Few preventive strategies exist against postoperative lung function impairment.
- Trial name
- tidalvolume (NCT00795964)
- Testing
- Randomized application of intraoperative tidal volume
- Where
- Germany
- Volunteers
- 101 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Nursing Education
Effect of ERAS Protocol Education on Nursing Students' Knowledge and Attitudes
Enhanced Recovery After Surgery (ERAS) is an evidence-based approach increasingly used in surgical care to improve recovery and reduce postoperative complications.
- Trial name
- (ERAS-NS) (NCT07588464)
- Testing
- ERAS Protocol Education
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Carpal Tunnel Syndrome
WALANT Versus Local Anesthesia With Tourniquet for Carpal Tunnel Decompression
This multicenter, randomized, double-blinded controlled trial compared two local anesthetic techniques for open carpal tunnel decompression in adults.
- Trial name
- WALANT vs LA-T (NCT07617064)
- Testing
- WALANT technique for carpal tunnel decompression, Local anesthesia with tourniquet for carpal tunnel decompression
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Misr University for Science and Technology
Systemic Inflammatory Response Syndrome, Sepsis
Impact of Vitamin D Supplementation on Hepcidin Levels and Transfusion Requirements in Surgical and Septic Patients
Acute inflammation induced by surgery and sepsis is complicated by the development of iron-restricted anemia due to the up-regulation of hepcidin.
- Conditions
- Systemic Inflammatory Response Syndrome, Sepsis, Surgical Injuries
- Trial name
- DEHEPTRA (NCT03001687)
- Testing
- enteral supplementation with vitamin D, blood collection 3mL
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Prostate Cancer
A Randomized Study of the Efficacy of Low Venous Pressure General Anesthesia Versus Combined Spinal-Epidural Anesthesia in Decreasing Blood Loss During Prostate Surgery
You are being asked to join the study because you have early stage prostate cancer and will have your prostate removed. The purpose of this study is to compare blood loss during surgery among two types of anesthesia.
- Trial name
- NCT00200187
- Testing
- low venous pressure general anesthesia, combined spinal-epidural anesthesia
- Where
- United States
- Volunteers
- 246 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Gastric Ulcer With Perforation But Without Obstruction, Colon Cancer
Domestic Surgical Robot Clinical Study
Central South University in collaboration with Tianjin University developed the first domestically produced Chinese minimally invasive surgical (MIS) robot system which named "Micro Hand S" in 2013.
- Conditions
- Gastric Ulcer With Perforation But Without Obstruction, Colon Cancer, Cholecystolithiasis, Appendicitis
- Trial name
- NCT02752698
- Testing
- Micro Hand S robotic surgery, laparoscopic surgery, da Vinci robotic surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Early Recovery in Elderly Patients, Cognitive Function
Effects of Sevoflurane vs Desflurane on Early Recovery and Cognitive Function in Elderly Patients Undergoing Scheduled Non-Cardiac Surgery
The goal of this clinical study is to compare the effects of desflurane versus sevoflurane on early postoperative recovery and cognitive function in elderly patients (aged 60 years and older, ASA I-III) undergoing elective…
- Trial name
- NCT07289945
- Testing
- Sevoflurane, Desflurane
- Where
- Tunisia
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Hopital Charles Nicolle
Erythrocyte Destruction
A Multi-dimensional Evaluation of the Effects of Linear Accelerator X-ray Irradiation on Red Blood Cells
This study aims to investigate the effects of linear accelerator X-ray irradiation on the structure, mechanics and functional characteristics of red blood cells recovered from patients with malignant tumors during surgery.
- Trial name
- NCT07416045
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Esophageal Cancer, Surgery Indication
Evaluation of the Administration of Artificial Nutrition by Feeding Jejunostomy During Neoadjuvant Treatment on Postoperative Morbidity in the Context of Esophageal or Stomach Cancer
Malnutrition is common at the time of diagnosis of esogastric cancers. However, there are no recommendations regarding preoperative nutritional support (type and duration) or on the impact of refeeding on postoperative morbidity…
- Conditions
- Esophageal Cancer, Surgery Indication, Malnourished, Neoadjuvant Treatment
- Trial name
- FREJENO (NCT07584577)
- Testing
- Enteral or parenteral nutrition
- Where
- France
- Volunteers
- 670 people
- Sponsor
- University Hospital, Bordeaux
Obesity, Quality of Life
A New Model of Exercise Referral Scheme Before and After Bariatric Surgery for People With Obesity
Obesity, defined by the WHO as an abnormal or excessive accumulation of fat that presents a risk to health, has reached pandemic levels, affecting approximately one-third of the world's population.
- Conditions
- Obesity, Quality of Life, Weight Loss
- Trial name
- B-FIT (NCT06541977)
- Testing
- Behavioral to reduce sedentary behvaior, Physical activity, Bariatric Surgery
- Volunteers
- 350 people
- Sponsor
- Fundació Universitària del Bages
Urinary Retention Postoperative
Effect of Phenazopyridine on Prolapse Surgery Voiding Trials
To determine if phenazopyridine reduces the rate of postoperative urinary retention after pelvic organ prolapse surgery.
- Trial name
- EPOV (NCT03065075)
- Testing
- Phenazopyridine
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Scars
A Randomized Split Scar Study of Suture Safe Treatment of Surgical Wounds to Minimize Scaring
The purpose of this study is to evaluate the effect SutureSafe dressings have on reducing scarring from an incision following an elective abdominoplasty (tummy tuck) procedure.
- Trial name
- NCT02620475
- Testing
- SutureSafe
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer, Head &Amp;Amp; Neck Squamous Cell Carcinoma
Proactive Risk-based Optimization & Notifications for Treatment & Outcomes in Head & Neck Cancer
Delays between surgery and the initiation of post-operative radiotherapy (S-PORT) in head and neck cancer (HNC) patients are prevalent and associated with worse oncologic outcomes.
- Conditions
- Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer, Head &Amp;Amp; Neck Squamous Cell Carcinoma, Larynx Squamous Cell Carcinoma
- Trial name
- PRONTO-HN (NCT07180901)
- Testing
- Proactive Risk-Based Optimization and Notifications for Treatment and Outcomes (PRONTO)
- Where
- Canada
- Volunteers
- 85 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Postoperative Infection Rates
Powder Topical Rifampicin on Reducing Infections After Neural Tube Defect Surgery in Infants
The correct timing and technique of neural tube defect (NTD) repairs significantly decreases the morbidity and mortality of NTD cases. However, infections related to the surgery are still common.
- Trial name
- NCT03198819
- Testing
- Local Rifampisin and İnrtravenous cefotaxime
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Yuzuncu Yil University
Metastatic Small Intestinal Adenocarcinoma, Recurrent Small Intestinal Carcinoma
Pembrolizumab in Treating Patients With Small Bowel Adenocarcinoma That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery
This phase II trial studies how well pembrolizumab works in treating patients with small bowel adenocarcinoma that has spread to other places in the body or that cannot be removed by surgery.
- Conditions
- Metastatic Small Intestinal Adenocarcinoma, Recurrent Small Intestinal Carcinoma, Unresectable Small Intestinal Carcinoma
- Trial name
- NCT02949219
- Testing
- Laboratory Biomarker Analysis, Pembrolizumab
- Where
- 8 sites in United States
- Volunteers
- 41 people
- Sponsor
- Academic and Community Cancer Research United
Surgery, Perioperative Complication
Post Discharge After Surgery Virtual Care With Remote Automated Monitoring Technology (PVC-RAM) Trial
The Post discharge after surgery Virtual Care with Remote Automated Monitoring technology (PVC-RAM) Trial is a multicentre, parallel group, superiority, randomized controlled trial to determine the effect of virtual care with…
- Conditions
- Surgery, Perioperative Complication, COVID
- Trial name
- PVC-RAM (NCT04344665)
- Testing
- Virtual Care and Remote Automated Monitoring
- Where
- 7 sites in Canada
- Volunteers
- 905 people
- Sponsor
- Population Health Research Institute
Hemodynamics, Patient Monitoring
Assessment of Fluid Responsiveness in Patients After Cardiac Surgery
To overcome the limited accuracy of functional hemodynamic parameters such as stroke volume and pulse pressure variation (SVV and PPV) during spontaneous breathing, a Passive Leg Raising (PLR) manoeuvre has been suggested as a…
- Trial name
- POP (NCT02571465)
- Testing
- Passive leg raising test and fluid challenge
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Triemli Hospital