Clinical trials: Operative Bleeding
Bone Loss
Maxillary Vascular Canal Thickness and Sinus Augmentation Bleeding
This study aims to evaluate the relationship between the maxillary intra-osseous vascular canal thickness as measured by volumetric tomography and the amount of intra-operative bleeding during open sinus floor augmentation.
- Trial name
- NCT05710497
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Marmara University
Acute Blood Loss Anemia, Postoperative Pain
Effect of Non-Dissection of the Inferior Rectus Sheath on Intraoperative Blood Loss
The purpose of this study is to evaluate the effect of non-dissecting the inferior rectus sheath during primary cesarean delivery on post-operative hemoglobin and post-operative pain control as measured by VAS score and opioid…
- Conditions
- Acute Blood Loss Anemia, Postoperative Pain, Pregnancy
- Trial name
- NCT02762773
- Testing
- non-dissection of inferior rectus sheath, control
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Postoperative Bleeding, Patient Satisfaction
Reducing Postoperative Bleeding After Hysterectomy Via Independent Closure of Vaginal Cuff Angles
The investigators propose prospectively evaluating if adding separate sutures to the angles of the vaginal cuff before running barbed suture reduces the incidence of patient's perception of bleeding after surgery.
- Conditions
- Postoperative Bleeding, Patient Satisfaction, Complications, Operative Time
- Trial name
- NCT05174988
- Testing
- Angle stitch
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Blood Clotting
Thromboelastography (TEG®) and Platelet Function in Patients on Anti-platelet Agents
Can a post-operative analysis using a simple blood test (Thromboelastography(TEG®)) and Platelet Mapping Assay (PMA™) be able to detect the occurence of clotting or bleeding complications in patients on blood thinning…
- Trial name
- NCT00901160
- Testing
- blood test
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- McMaster University
Hemorrhoids
Bleeding in Laser Haemorrhoidoplasty
Treatment options for haemorrhoid can be classified mainly into lifestyle modification, medical and procedural. Laser haemorrhoidoplasty (LHP) is a minimally invasive procedure which is effective in treating grade 2-4…
- Trial name
- NCT04667169
- Testing
- Haemorrhoidal Artery Ligation, Laser Haemorrhoidoplasty
- Where
- Malaysia
- Volunteers
- 76 people
- Sponsor
- University of Malaya
Pharmacological Action
The Effect of Tranexamic Acid. A Randomised Study of Patients Undergoing Elective Lumbar Spine Surgery.
In this randomized double blind placebo controlled study of tranexamic acid during minor spinal surgery, mean postoperative blood loss in the patients who received TXA was statistically significantly lower compared to placebo.
- Trial name
- NCT03714360
- Testing
- Tranexamic Acid, Sodium Chloride 0,9%
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Mikkel Østerheden Andersen
Intra-operative Bleeding
Oxidized Cellulose hEmostAsis evaluatioN
The purpose of this study is to evaluate the safety and effectiveness of Traumastem to help stop bleeding in participants undergoing open cardiac, intra-abdominal (including retroperitoneal) and pelvic surgery as compared to…
- Trial name
- OCEAN (NCT01637025)
- Testing
- Oxidized cellulose strip, Oxidized regenerated cellulose strip
- Where
- 24 sites in Czechia, Germany and 2 more
- Volunteers
- 111 people
- Sponsor
- Baxter Healthcare Corporation
Chronic Subdural Hematoma
Effect of Different Intravenous Fluids on Post-operative Chronic Subdural Hematoma Size and Recurrence
This study aims to reduce the recurrence rate of chronic subdural hematomas (CSDH) by manipulating the post-operative intravenous fluid use.
- Trial name
- NCT03831997
- Testing
- Dextrose 5% W/ Sodium Chloride 0.225%
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Carilion Clinic
Post Cardiac Surgery Systemic Inflammatory Response
Single Dose Administration of Alpha-1 Anti-Trypsin for the Amelioration of Organ Injury in Patients Undergoing Cardiac Surgery
Protocol Summary STUDY DESIGN A pilot, prospective, double blind, randomized, placebo controlled study. STUDY POPULATION Patients assigned to elective CABG with cardiopulmonary bypass (CPB) at the Department of Cardiothoracic…
- Trial name
- NCT02191839
- Testing
- Alpha 1-Antitrypsin
- Volunteers
- 20 people
- Sponsor
- Soroka University Medical Center
Surgical Blood Loss
Assessment of Hematologic Parameters Before and After Bimaxillary Orthognathic Surgery
The purpose of the present study was to compare some hematologic parameters and operation time in patients who underwent esthetic bimaxillary surgery under hypotensive anesthesia.
- Trial name
- NCT02364765
- Testing
- Remifentanil
- Where
- Brazil
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Ecchymosis
The Utility of Peri-operative Arnica Montana for Reduction of Ecchymosis in Rhinoplasty Surgery
Arnica montana is a homeopathic drug that is made in accordance with the official methods of the Homeopathic Pharmacopoeia of the United States (HPUS) and is commonly used by cosmetic surgeons throughout the world, although there…
- Trial name
- NCT01164644
- Testing
- Arnica montana
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Wisconsin, Madison
Intraoperative Bleeding, Post-operative Bleeding
Study to Compare the Addition of Floseal to Our Standard of Care to Control Post Operative Bleeding in TKR
The purpose of this study is to compare Floseal to our standard of care (SOC) to decrease intraoperative and immediate post-operative bleeding.
- Trial name
- NCT01891461
- Testing
- Floseal
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Postpartum Hemorrhage, Pain
Do Elastic Abdominal Binders Reduce Post Operative Pain and Blood Loss?
This is a pilot study investigating the use of abdominal binders after cesarean sections. The researchers are testing whether elastic abdominal binders improve postoperative pain control and reduce postoperative blood loss.
- Trial name
- NCT01786330
- Testing
- Procare abdominal binder, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zachary Kuhlmann, DO
Primary Total Knee Arthroplasty, Primary Total Hip Arthroplasty
Investigating the Effect of Intravenous and Oral Tranexamic Acid on Blood Loss After Primary Hip and Knee Arthroplasty
Patients having a hip or knee replacement can lose almost a third of their blood during and after the operation. Many patients, especially those who are older will need a blood transfusion, suffer from anaemia, or have a slow…
- Trial name
- TRAC-24 (NCT03690037)
- Testing
- Tranexamic Acid 100 MG/ML, Tranexamic Acid 500 MG
- Where
- United Kingdom
- Volunteers
- 1,089 people
- Sponsor
- Belfast Health and Social Care Trust
Blood Loss, Surgical, Blood Loss, Postoperative
Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate
Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate, Pre-operative Administration.
- Trial name
- NCT04656067
- Testing
- Oxytocin ,Tranexamic acid and Ethamsylate
- Where
- Egypt
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Surgical Blood Loss, Surgical Hemorrhage
TEG Use in Children Undergoing Procedures With High Anticipated Blood Loss
The research team proposes a prospective, observational study to better understand how TEG can be useful in guiding clinical practice in the Main OR for subject's undergoing high transfusion risk surgeries.
- Conditions
- Surgical Blood Loss, Surgical Hemorrhage, Post Operative Hemorrhage
- Trial name
- NCT05379530
- Testing
- Thromboelastography (TEG), Anesthesia Provider Survey
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Alagille Syndrome, Pulmonary Artery Stenoses
Decreasing Hemorrhage Risk in Children With Alagille Syndrome
The goal of this interventional study is to test a hemostasis screening protocol and cardiac peri-procedural and post-operative hemostasis pathway to improving bleeding complications and improve patient survival for children with…
- Conditions
- Alagille Syndrome, Pulmonary Artery Stenoses, Acquired Von Willebrand Disease
- Trial name
- NCT05846854
- Testing
- Assessment for bleeding disorder with tailored post-operative care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Myoma;Uterus, Blood Loss
the Effect of Misoprostol on Intra-operative Blood Loss During Myomectomy Operation
assess the effect of using misoprostol in abdominal myomectomy operations on blood loss, duration of the operation and possible operative complications.
- Trial name
- NCT03483142
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- ahmed nagy shaker ramadan
Peri-operative Hemorrhage or Hematoma, Surgery
Preventive EXACYL® on Perioperative Bleeding During Orthognathism of Maxillary Surgery
Prospective, randomized, double-blind, placebo-controlled, mono center, Phase III trial to compare EXACYL in preventive with placebo on perioperatory bleeding in orthognathism surgery.
- Conditions
- Peri-operative Hemorrhage or Hematoma, Surgery, Retrognathism
- Trial name
- LEFORTEXACYL (NCT02702128)
- Testing
- Tranexamic Acid, saline solution
- Where
- France
- Volunteers
- 157 people
- Sponsor
- University Hospital, Lille
Nasolacrimal Tract Obstruction
Tranexamic Acid in Dacryocystorhinostomy
Single dose tranexamic acid (TA) before dacryocystorhinostomy (DCR) operation: a prospective, double blind, placebo controlled study.
- Trial name
- TA-DCR (NCT01221909)
- Testing
- Tranexamic acid, saline solution
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- HaEmek Medical Center, Israel