Clinical trials: Operative Wound
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Surgical Site Infection, Surgical Wound Infection
Floraseal Versus Iodine Impregnated Adhesive Drapes
Infection after total joint arthroplasty can have devastating consequences. Adhesive drapes have been traditionally used at our institution to help reduce the risk of wound contamination and infection by superficial skin flora.
- Trial name
- NCT03466489
- Testing
- Floraseal
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Cesarean Section
Cosmetic Outcomes With Tissue Adhesive (2-octylcyanoacrylate) or Staples in Repeated Cesarean Section
Recent clinical trials were developed to test the outcomes of skin closure with tissue adhesive, staples and monofilament synthetic suture after cesarean section with Pfannenstiel incision: both clinical outcomes such as blood…
- Trial name
- NCT04302597
- Testing
- Staples, Tissue adhesive
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Università degli Studi dell'Insubria
Surgical Site Infection in Obese Women Undergoing C-section
Use of 48 Hour Course of Antibiotics to Prevent Surgical Site Infection in Obese Patients Undergoing Cesarean Delivery
The purpose of this study is to evaluate if preoperative antibiotics, followed by 48 hour course of broad spectrum antibiotics prevents wound infection complications in patients that are obese who undergo cesarean section.
- Trial name
- SSI (NCT01194115)
- Testing
- cephalexin & metronidazole
- Where
- United States
- Volunteers
- 475 people
- Sponsor
- University of Cincinnati
Benign or Malignant Diseases With Indication for Laparoscopic or Robotic Colorectal Resection
A Study Comparing Skin Adhesive With Staple for Surgical Incision Closure After Laparoscopic / Robotic Bowel Resection
INTRODUCTION Liquid skin adhesive (LSA) has benefits over other closure methods. Especially it is less invasive, quicker to apply, and better in cosmesis.
- Trial name
- NCT04969016
- Testing
- LSA (liquid skin adhesive), stapler
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Surgical Wound, Tissue Adhesion
Skin Closure With Tissue Adhesives vs. Subcuticular Suture After Robotic Urogynecologic Procedures
To compare skin closure via subcuticular suture versus tissue adhesive (Dermabond) in urogynecological robotic surgeries. The primary outcome is incision cosmesis at the 12 week follow up visit.
- Trial name
- NCT03891004
- Testing
- Subcuticular Skin Closure, Tissue Adhesives
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- St. John Hospital & Medical Center
Drainage
Evaluating the Effectiveness of 2 Surgical Skin Preparation Methods in Reducing Surgical Wound Drainage After Total Hip or Knee Replacement
Surgical skin complications can be costly and could contribute to extended in-patient stay following total joint replacement or even the need for re-admission.
- Trial name
- NCT01097135
- Testing
- Duraprep Surgical Solution
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Rothman Institute Orthopaedics
Dehisced Surgical Wounds
Study of NanoDOX Hydrogel vs Placebo for Dehisced Surgical Wounds
The purpose of this study is to determine the effects of NanoDOX Hydrogel versus Placebo Hydrogel on Dehisced Surgical Wounds.
- Trial name
- NCT01547325
- Testing
- NanoDOX 1% doxycycline monohydrate Hydrogel
- Where
- United States
- Sponsor
- NanoSHIFT LLC
Cesarean Section Complications, Wound Breakdown
Antimicrobial Dressing Versus Standard Dressing in Obese Women Undergoing Cesarean Delivery
This will be an open label pilot randomized controlled clinical trial. Women undergoing cesarean delivery will be randomized to have standard wound dressing care or chlorohexidine gluconate (CHG) impregnated wound dressing…
- Conditions
- Cesarean Section Complications, Wound Breakdown, Wound Infection, Satisfaction
- Trial name
- NCT03887299
- Testing
- ReliaTect™ Post-Op Dressing (contains chlorohexidine gluconate or CHG), Standard Wound Care
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Pain
Multimodal Analgesia With Interfascial Continuous Wound Infiltration: A Randomized Clinical Trial
Objectives: For major laparoscopic surgery, as with open surgery a multimodal analgesia plan can help control postoperative pain.
- Trial name
- NCT02223533
- Testing
- 19Gx500-mm Pajunk InfiltraLong® catheter, morphine
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Hospital Galdakao-Usansolo
Surgical Wound Dehiscence
A Study, Performed in Subjects With Post Traumatic-post Surgical ,Venus Insufficiency and Diabetic Hard to Heal/Chronic Wounds, to Evaluate the Safety and Efficacy of PolyHeal-2 Versus PolyHeal in Once Daily Regimen
This is a double-blind , randomized, controlled, two-arm study aiming to evaluate the safety and efficacy of Polyheal-2 vs PolyHeal, in once daily application as compared to historical control.
- Trial name
- NCT01679678
- Testing
- PolyHeal 2, Polyheal
- Where
- 4 sites in Israel
- Volunteers
- 15 people
- Sponsor
- MediWound Ltd
Surgical Wound Infection, Surgical Site Infection
Bacteriology of sUrGical Site INfection Following Surgery for Intestinal Failure
This is a prospective observational study of patients undergoing planned surgery for intestinal failure. The aims of the study are: To prospectively characterise preoperative bacterial populations amongst patients undergoing…
- Conditions
- Surgical Wound Infection, Surgical Site Infection, Bacteria Infection Mechanism, Intestinal Disease
- Trial name
- BUGS-IN-IF (NCT05234515)
- Testing
- Microbiology swab, Questionnaire
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- London North West Healthcare NHS Trust
Surgical Site Infections
Ampicillin/Sulbactam Versus Cefuroxime as Antimicrobial Prophylaxis for Cesarean Section
The efficacy and safety of a single dose of ampicillin/sulbactam compared to a single dose of cefuroxime at cord clamp for prevention of postcesarean infectious morbidity has not been assessed.
- Trial name
- NCT01138852
- Testing
- Ampicillin-sulbactam, Cefuroxime
- Volunteers
- 176 people
- Sponsor
- Attikon Hospital
Cubital Tunnel Syndrome
Treatment for Cubital Tunnel Syndrome
The researchers want to find out the best treatment for cubital tunnel. The researchers establish the degree of nerve compression and then the patients are randomised to different treatment alternatives, ranging from conservative…
- Trial name
- NCT00184158
- Testing
- decompression
- Where
- Norway
- Volunteers
- 81 people
- Sponsor
- Norwegian University of Science and Technology
Ankle Malleolus Fracture Bimalleolar, Fracture of Medial Malleolus
Non--operative Treatment of the Medial Malleolus in bi- and Trimalleolar Ankle Fractures
The purpose of this study was to determine if internal fixation of the medial malleolus is necessary following open reduction and internal fixation of the lateral and, if required, the posterior malleolus treating displaced bi-or…
- Conditions
- Ankle Malleolus Fracture Bimalleolar, Fracture of Medial Malleolus, Fracture of Ankle
- Trial name
- NCT01441817
- Testing
- Internal fixation
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Surgical Site Infection
Air Barrier System for the Prevention of Surgical Site Infection
Airborne particles are present in all indoor environments including the operating room. Most of these particles come from the surgical staff moving around in the room, positioning of the patient during surgery, and the movement…
- Trial name
- ABS (NCT01610271)
- Testing
- Air Barrier System
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Nimbic Systems, LLC
Skin Closure of Surgical Incisions by Tissue Glue vs Suture
Tissue Glue (Cyanoacrylate) Versus Conventional Suture in Kidney Donors
By means of a prospective, randomised trial the investigators want to examine skin closure in living donors - subjected to laparoscopic, hand-assisted nephrectomy - by tissue glue (Cyanoacrylate (Liquiband)) versus conventional…
- Trial name
- TG-CYANO (NCT01521871)
- Testing
- Skin wound closure by tissue glue, Skin wound closure by conventional suture + dressing
- Where
- Norway
- Volunteers
- 64 people
- Sponsor
- Oslo University Hospital
Laparoscopic Cholecystectomy
Single Incision Versus Three Port Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy (LC) became the standard treatment for symptomatic gallbladder disease. Single incision laparoscopic surgery (SILS) was developed with the aim of reducing the invasiveness of conventional laparoscopy.
- Trial name
- NCT03067038
- Testing
- Single incision laparoscopic cholecystectomy, Three port laparoscopic cholecystectomy
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- South Valley University
Gingival Recession, Localized
Extended Platelet- Rich Fibrin Membrane Combined With Vestibular Incision Subperiosteal Tunnel Access Technique to Treat Localized Gingival Recession
This study will be performed to clinically evaluate and compare the effectiveness of extended platelet-rich fibrin (e-PRF) membrane versus de-epithelized free gingival graft (DFGG) in combination with vestibular incision…
- Trial name
- alb prf REC (NCT07079293)
- Testing
- Preparation of Extended PRF, Harvesting of Free Gingival Graft and preparation of CTG, VISTA technique
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Carpal Tunnel Syndrome
Comparison of Conventional Versus Transverse Mini-Incision Technique for Carpal Tunnel Release
This study aimed at to fill the gaps by comparing the surgical outcomes of the conventional versus transverse mini-incision technique for carpal tunnel syndrome in terms of pain and functional outcomes.
- Trial name
- NCT07018011
- Testing
- Conventional open CTR, Transverse mini-incision technique
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- RESnTEC, Institute of Research