Clinical trials: Operative Wound
Wounds
Octylseal Surgical Adhesive in General Surgery
The purpose of this study is to evaluate how surgical adhesive is used.
- Trial name
- NCT01514383
- Testing
- Cyanoacrylate (Octylseal )
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Medline Industries
All Diseases That Require Gastrointestinal Open Surgery
Subcutaneous Closed-Suction Drainage Affects Surgical Wounds Healing in Lower Gastrointestinal Open Surgery: a Randomized Controlled Study
This is a single-center, randomized controlled trial to evaluate whether subcutaneous closed-suction drainage would decrease the incidence of poor surgical site healing in lower gastrointestinal open surgery.
- Trial name
- NCT05318430
- Testing
- Subcutaneous closed-suction drainage device
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Beijing Friendship Hospital
Surgical Site Infection, Risk Assessment
Pre-operative Risk Assessment of Surgical Site Infection After Cardiac Surgery
Surgical site infections (SSI) are serious complications accounting for 20% of all the healthcare-associated infections and are considered the second most frequent type of hospital-acquired infection in Europe and the United…
- Conditions
- Surgical Site Infection, Risk Assessment, Cardiac Surgery
- Trial name
- NCT04762446
- Where
- 3 sites in United Kingdom
- Volunteers
- 6,379 people
- Sponsor
- Barts & The London NHS Trust
Carpal Tunnel Syndrome
Scalpel Versus Electrocautery for Surgical Skin Incision in Open Carpal Tunnel Release
The use of electrocautery for surgical skin incision in general surgery is known to decrease post-operative pain. This study compares the use of scalpel and electrocautery for surgical skin incision in open carpal tunnel release…
- Trial name
- OCTR-Electro (NCT02791529)
- Testing
- Electrocautery, Scalpel
- Volunteers
- 16 people
- Sponsor
- Turku University Hospital
Acute Appendicitis
Single-incision Laparoscopic Surgery in Acute Abdomen
Since Semm et.al. reported the first case of laparoscopic appendectomy in 1983, minimally invasive surgery has become the main stay for treating of many surgical diseases.
- Trial name
- NCT03198065
- Testing
- Hand-made glove setting, Commercialized single-incision multiport setting
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Incisional Hernia, Cholecystectomy, Laparoscopic
Trocar Site Hernia After Laparoscopic Cholecystectomy, Supra Versus Infraumbilical Incision for Umbilical Trocar Entry
Trocar site hernia is a specific complication of laparoscopic surgery. The increasingly frequent use of the laparoscopic approach has resulted in an increase in the number of hernias, mainly at the umbilical area.
- Trial name
- HOT (NCT04254237)
- Testing
- Infraumbilical Hasson trocar incision, Supraumbilical Hasson trocar incision
- Where
- 3 sites in Spain
- Volunteers
- 130 people
- Sponsor
- Complejo Hospitalario La Mancha Centro
Dehiscence of Laparotomy Wound, Surgical Wound Infection
Short Stitch Monomax®
A number of studies identifies abdominal hernia as the most frequent postoperative complication following laparotomy with percentages of 9-20% - depending on duration of follow-up.
- Trial name
- Short-Stitch (NCT01938222)
- Testing
- Short Stitch
- Where
- Germany
- Volunteers
- 351 people
- Sponsor
- Diakonie-Klinikum Schwäbisch Hall gGmbH
Anal Fistula
Marsupialization of Anal Fistulotomy Wound Accelerates Healing and Decreases Post Operative Pain
comparison between to groups of patients with simple anal fistula one group underwent sistulotomy the other underwent fistulotomy and marsupialization of the wound edges , the investigator tested the incidence of postoperative…
- Trial name
- NCT04155905
- Testing
- fistulotomy and marsupialization of wound edges, fistulotomy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Zagazig University
Incisional Hernia
Preventive PICO on Surgical Wounds After Large Incisional Hernia Repair
To determine the efficacy on decreasing the rate of surgical wound complications in patients undergoing repair of large incisional hernias, after the prophylactic application of a single-use negative pressure therapy dressing…
- Trial name
- PICO (NCT03576222)
- Testing
- PICO DRESSING, MEPORE dressing
- Where
- Spain
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Surgical Site Infection
Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™ (ZX-ZP-0055)
This is a randomized, paired-comparisons design where each subject receives two of the planned treatments.
- Trial name
- NCT02296645
- Testing
- ZuraPrep, ChloraPrep
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Ankyloglossia
Case Series of Infants With Anterior Ankyloglossia Being Treated by the Sublingual Neonatal Incision Platform Device
A study assessing the feasibility of a novel device designed specifically to treat infant tongue-tie.
- Trial name
- SNIP (NCT07655895)
- Testing
- Frenectomy of anterior ankylogossia using the novel device
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Europa Life Sciences Limited
Non-small Cell Lung Cancer
Comparison of Lobectomy and Segmentectomy for cT1aN0M0 Peripheral NSCLC
Anatomic segmentectomy may be a less invasive type of surgery than lobectomy for cT1aN0M0 peripheral NSCLC and may retain more pulmonary function.
- Trial name
- NCT02481661
- Testing
- segmentectomy
- Where
- China
- Volunteers
- 610 people
- Sponsor
- Zhejiang Cancer Hospital
Surgical Site Infection
AO Multicenter Intervention Trial for Prevention of Surgical Site Infection
This study is designed to collect data from 8,476 fracture patients during a pre-and post-intervention phases of two years length each. The intervention consists on the implementation of the AOT SSI Prevention Bundle. D
- Trial name
- AOPOSSI (NCT03380273)
- Testing
- Implementation of the AO Trauma SSI Prevention Bundle
- Where
- 14 sites in United States, Argentina and 4 more
- Volunteers
- 222 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Gingival Pigmentation
Effect of Non-eugenol Periodontal Pack With and Without PRF on Post-operative Pain and Wound Healing After Gingival Depigmentation
In an era where less than ideal esthetics is not accepted, the request for esthetic procedures is widely sought after. Melanin, a brown pigment, is the most common natural pigment contributing to endogenous pigmentation of…
- Trial name
- NCT04495205
- Testing
- PRF under non-eugenol containing periodontal pack, Non-eugenol containing periodontal pack
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Surgical Wound
RESPECT Trial - (Rapid Extravascular Sealing Via PercutanEous Collagen ImplanT)
The objective of this trial is to demonstrate the safety and effectiveness of the Cardiva VASCADE™ Vascular Closure System (VCS) in sealing femoral arterial access sites.
- Trial name
- RESPECT (NCT01297322)
- Testing
- Manual compression, Cardiva VASCADE™ Vascular Closure System
- Where
- 21 sites in United States, Australia
- Volunteers
- 420 people
- Sponsor
- Cardiva Medical, Inc.
Colon Cancer
Evaluation of the Extraction-site, - Midline Incision vs Off-midline Incision-
The purpose of this study is to evaluate the midline extraction incision in patients with colon cancer. A prospective randomized controlled trial is conducted to compare midline extraction incision with off-midline extraction…
- Trial name
- NCT02253303
- Testing
- midline incision or off-midline incision
- Volunteers
- 100 people
- Sponsor
- Hiroki Yamaue
Fractures, Bone
Continuous Passive Motion Following Fixation of Pelvic and Knee Fractures
The investigators will directly compare the visual analog scale scores and narcotic pain medication requirements in the patients who have continuous passive motion (CPM) versus those who do not during the course of the hospital…
- Trial name
- NCT04389749
- Testing
- CPM
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Cincinnati
Surgical Incision, Malocclusion
Efficacy of Piezosurgey Corticotomy (a Minimally Invasive Surgical Technique) in Accelerating Orthodontic Alignment
Applying flapless piezocision corticotomies on the alveolar bone and separating anterior mandibular teeth using a piezosurgery device (i.e.
- Trial name
- NCT02977221
- Testing
- Piezosurgery
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Atherosclerosis
Platelet Rich Plasma Study in Lower Extremity Bypass Surgery
The use of platelet rich plasma will decrease wound infection postop.
- Trial name
- PRP (NCT00517452)
- Volunteers
- 81 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Dysbiosis, Gut -microbiota
Impact of Probiotics on Gut Microbiome During Antibiotic Prophylaxis in Elective Orthopedic Surgery
This study aims to evaluate whether probiotics can help maintain a healthy gut microbiome in patients receiving prophylactic antibiotics during elective orthopedic surgery.
- Conditions
- Dysbiosis, Gut -microbiota, Microbiome Analysis, Probiotic
- Trial name
- NCT06791993
- Testing
- Probiotic with Human Milk Oligosaccharides (HMO)
- Where
- 6 sites in United States, Thailand and 1 more
- Volunteers
- 60 people
- Sponsor
- Acibadem Maslak Hospital