Clinical trials: Ophthalmic Surgery
Endophthalmitis, Cataract
Early Vitrectomy for Endophthalmitis After Cataract Surgery
Post-operative infectious endophthalmitis is devastating condition that causes a diffuse intraocular inflammation and may lead to blindness.
- Conditions
- Endophthalmitis, Cataract, Vitreous Detachment, Retinal Detachment
- Trial name
- NCT05249413
- Testing
- Early 23-gauge pars-plana vitrectomy
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Benha University
Amblyopia, Strabismus
Binocular Treatment of Amblyopia Before and After Strabismus Surgery
The primary objective of this study is to assess the effectiveness of an investigational binocular treatment in improving vision in strabismic amblyopes (i.e., patients with lazy eye, or poor vision in one eye due to a present or…
- Trial name
- NCT01791946
- Testing
- Binocular Treatment
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Eye Enucleation, Orbit Surgery
Post Enucleation Socket Syndrome Study
Superior sulcus deformity in post-enucleation socket syndrome (PESS) may pose a significant cosmetic blemish after enucleation surgery despite apparently adequate orbital volume replacement.
- Conditions
- Eye Enucleation, Orbit Surgery, Postoperative Complications
- Trial name
- NCT00347282
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Epiretinal Membrane, Internal Limiting Membrane Wrinkling
Fovea ERM After Fovea-sparing ILM Peeling
To report cases who had received previous fovea-sparing internal limiting peeling membrane and developed secondary fovea epiretinal membrane contraction
- Trial name
- NCT04445142
- Testing
- fovea-sparing internal limiting membrane peeling
- Where
- Taiwan
- Volunteers
- 3 people
- Sponsor
- Changhua Christian Hospital
Open Angle Glaucoma, Ocular Hypertension
Efficacy and Safety of the ExPRESS Implant Versus Deep Sclerectomy in Combined Surgery
The Ex-PRESS Glaucoma Filtration Device is a small, non-valved implant that was designed to lower intraocular pressure (IOP) by shunting aqueous humor from the anterior chamber into the subconjunctival space.
- Trial name
- NCT03201354
- Testing
- Filtration surgery with Ex-PRESS, Non penetrating deep sclerectomy, Cataract extraction
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Institut Catala de Retina
Corneal Edema, Visual Acuity
Effect of Topical Brimonidine on Post Cataract Surgery Corneal Edema
Most patients undergoing cataract surgery suffer from corneal edema after the surgery. Brimonidine drops are a well known and safe Anti-glaucoma medication.
- Trial name
- NCT00800423
- Testing
- Brimonidine Tartrate 0.2%, Timolol maleate 0.5%
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Rabin Medical Center
Cataract
Assesment of Intermediate Vision After BIL Cataract Surgery
The goal of this observational study is to learn about the intermediate and near vision in patiënts who underwent cataract surgery with a specific technique, called "bag in the lens".
- Trial name
- NCT06364761
- Testing
- Bag in the lens cataract surgery
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Pain, Inflammation
Efficacy Study of Bromfenac Ophthalmic Solution in Patients Undergoing Cataract Surgery
Efficacy study of Bromfenac Ophthalmic Solution in cataract surgery
- Trial name
- NCT00853970
- Testing
- Bromfenac Ophthalmic Solution
- Where
- United States
- Volunteers
- 299 people
- Sponsor
- Bausch & Lomb Incorporated
Intracranial Pressure Increase, Postoperative Cognitive Dysfunction
The Effect of Optic Nerve Diameter on Postoperative Cognitive Function in Laparoscopic Hysterectomy
Prospective study, 40 patients ASA 2-3, 30-75 years old who were planned for laparoscopic hysterectomy operation will be included.One day before the operation and postoperative 1.3.7.
- Trial name
- NCT05286697
- Testing
- measuring optic nerve diameter
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Marmara University
Intravitreal Bevacizumab Injection, Pars Plana Vitrectomy
Preoperative Injection of Bevacizumab Prior to Vitreoretinal Surgery in Diabetic Tractional Retinal Detachment
Vitreoretinal surgery for epiretinal proliferation tractional retinal detachment associated with proliferative diabetic retinopathy (PDR) is often complicated by hemorrhage from fibrovascular tissue.
- Conditions
- Intravitreal Bevacizumab Injection, Pars Plana Vitrectomy, Tractional Retinal Detachment, Diabetic Retinopathy
- Trial name
- NCT00548197
- Testing
- Bevacizumab
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Iran University of Medical Sciences
Pediatric Cataract
The Cohort Study of Pediatric Cataract
This retrospective-prospective bidirectional cohort study aims to observe ocular parameter changes, different surgical/vision recovery strategies and postoperative adverse effects among young children with cataract.
- Trial name
- NCT05472844
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Primary Open Angle Glaucoma
Electroretinogram and Retinal Vascular Changes After Cataract Surgery
To compare electrophysiological and Optical coherence tomography angiography of optic disc and macula changes after uneventful phacoemulsification between normal and cataractus patients with primary open angle glaucoma.
- Trial name
- NCT05871034
- Testing
- phacoemulsification
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Macular Holes
Comparative Analysis of Large Macular Hole Surgeries
This study compares the anatomical and visual outcomes in a large series of patients affected by idiopathic macular holes larger than 400 µm treated using pars plana vitrectomy and gas tamponade combined with internal limiting…
- Trial name
- CAOLMHS (NCT04116892)
- Testing
- the Cover group, the Fill group, the peeling group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Paralytic Lagophthalmos, Leprosy--Patients
Modified Tarsorrhaphy vs Gold Weight Implant for Paralytic Lagophthalmos in Leprosy Patients
This study aims to compare the effectivity and efficiency of Modified Tarsorrhaphy (MT) technique and Gold Weight Implant (GWI) technique as a surgical treatment of paralytic lagophthalmos in leprosy patients.
- Trial name
- NCT04944498
- Testing
- Modified Tarsorrhaphy, Gold Weight Implant
- Where
- 3 sites in Indonesia
- Volunteers
- 19 people
- Sponsor
- Yunia Irawati
Pterygium
Pterygium Head Body MMC1: Two Different Surgical Procedures and Their Effect on Endothelial Cell Count.
To evaluate changes in endothelial cell count after pterygium surgery with mitomycin C (MMC) 0.02%
- Trial name
- PHB-MMC1 (NCT02641132)
- Testing
- Mitomycin C 0.02%, Pterygium surgery
- Where
- 2 sites in Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Cataract
A Proposed Intervention to Decrease Resident-Performed Cataract Surgery Cancellation
The investigators aim to investigate the impact of mandating on-site pre-admission testing on cataract cancellation rates in a randomized, prospective, intervention study.
- Trial name
- NCT02621840
- Testing
- Mandatory On-Site Pre-Admission Testing
- Where
- United States
- Volunteers
- 442 people
- Sponsor
- Wills Eye
Pterygium of Conjunctiva and Cornea, Pterygium of Both Eyes
Clinical Outcomes of Sutured Versus Sutureless Conjunctival Autograft in Primary Pterygium Excision
The goal of this study is to find out if a certain technique in pterygium excision surgery ,using no sutures, is better than the technique mostly used ,which uses sutures.
- Conditions
- Pterygium of Conjunctiva and Cornea, Pterygium of Both Eyes, Pterygium
- Trial name
- NCT06734663
- Testing
- Clinical outcomes of sutured versus sutureless conjunctival autograft in primary pterygium excision, pterygium excision and conjuctival graft suturing, pterygium excision and conjuctival graft placement by autologous blood
- Where
- 2 sites in Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Cataract Complicated, Cataract Complications Operations
Performance of Two Sclera Fixated Intraocular Lens Concepts
To evaluate and compare the post-operative outcome of two different sceral fixated IOL concepts, the Yamane method (ZA9003, J\&J, USA) and the Carlevale IOL (FIL-SSF, Soleko, Italy).
- Trial name
- Carlevale (NCT05779306)
- Testing
- IOL Master 700, Casia-2, MS-39
- Where
- Austria
- Volunteers
- 26 people
- Sponsor
- Johannes Kepler University of Linz
Glaucoma
Post-Operative Sub-Tenon Kenalog in Glaucoma Filtering Surgery
Determine efficacy of sub tenon kenalog injections for post-operative management of trabeculectomy procedures.
- Trial name
- NCT00238563
- Testing
- Triamcinolone injection, sub-tenon
- Where
- 2 sites in United States
- Sponsor
- Stanford University
Strabismus
Exercise Interventions for Improving Eye Control Post Strabismus Surgery
The purpose of this study will be focused on the following issue: 1. The aim of this study is to determine therapeutic effect of postoperative eye exercises on improving eye control after the strabismus surgery.
- Trial name
- NCT05303779
- Testing
- Exercise Interventions of Eye Muscles, Medication and eye glasses
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
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