Clinical trials: Ophthalmic Surgery
Cataract
Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
- Trial name
- NCT00704418
- Testing
- Bromfenac
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Bausch & Lomb Incorporated
Strabismus, Surgery
Povidone-iodine Antisepsis for Strabismus Surgery
The purpose of this study is to compare the efficacy of 5 % vs. 1.25 % povidone-iodine (PI) as preoperative antiseptic prior to strabismus surgery in children as a prophylaxis of endophthalmitis.
- Conditions
- Strabismus, Surgery, Endophthalmitis
- Trial name
- PASS (NCT00461656)
- Testing
- Preoperative conjunctival irrigation with 5% or 1.25% PI
- Where
- 9 sites in Germany, Netherlands
- Volunteers
- 70 people
- Sponsor
- Erasmus Medical Center
Cataract
Efficacy of Dextenza Insert in Upper vs Lower Punctum Following Cataract Surgery With PCIOL.
To assess the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert in the operating room following cataract surgery/intraocular lens implant (IOL) with or without iStent/Hydrus/Goniotomy…
- Trial name
- DEXTENZA (NCT05372315)
- Testing
- Dextenza 0.4Mg Ophthalmic Insert
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Iworks Laser and Vision Center
Cardiovascular Surgical Procedures
The Effect of Eye Mask and Earplugs on Sleep Quality and Delirium in Coronary Artery Bypass Graft Patients: A Randomized Controlled Study
Coronary artery bypass grafting is the most commonly performed surgical procedure among cardiovascular diseases. Nursing care for patients undergoing cardiac surgery involves a process that includes preoperative preparation and…
- Trial name
- NCT06752980
- Testing
- Eye mask, Earplugs, Eye Mask and Earplugs
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Necmettin Erbakan University
Surgery, Sedation
Oral Versus Intravenous Sedation for Ocular Procedures
The purpose of this study is to evaluate patient satisfaction after eye surgery when given a capsule compared to an intravenous (IV) dose of sedation (calming medication).
- Trial name
- NCT03246724
- Testing
- Triazolam, Midazolam, Microcrystalline Cellulose
- Where
- United States
- Volunteers
- 327 people
- Sponsor
- Boston Medical Center
Cataract, Cataract Surgery
Binocular and Monocular Distance-Corrected Visual Performance and Defocus Characteristics of Clareon Truplus Intraocular Lens (IOL)
This study aims to generate data that characterizes visual outcomes, including the binocular distance-corrected intermediate visual acuity (DCIVA) at 66cm or defocus behavior, of the Clareon TruPlus modified monofocal intraocular…
- Conditions
- Cataract, Cataract Surgery, Cataract Bilateral, Cataract (Post-operative Cataract Surgery Follow-up)
- Trial name
- BMVDI (NCT07589894)
- Testing
- Clareon TruPlus IOL
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Colvard Kandavel Eye Center
Intraocular Pressure, Neovascular Glaucoma
Aflibercept as Adjunctive Treatment for Filtration Surgery in Neovascular Glaucoma
Purpose: To investigate intravitreal aflibercept (IVA) injection as an adjunctive treatment to trabeculectomy with mitomycin C (TMC) and panretinal photocoagulation (PRP) for neovascular glaucoma (NVG).
- Conditions
- Intraocular Pressure, Neovascular Glaucoma, Vascular Endothelial Growth Factor Overexpression, Glaucoma Secondary to Eye Inflammation
- Trial name
- NCT04970251
- Testing
- Aflibercept Ophthalmic
- Where
- Thailand
- Volunteers
- 5 people
- Sponsor
- Siriraj Hospital
Pediatric Glaucoma
Combined Phacoaspiration and Angle Surgery Versus Phacoaspiration in Pediatric Cataract
The aim of this study is to report the effectiveness of phacoaspiration when combined with angle surgery in preventing postoperative glaucoma following pediatric cataract surgery
- Trial name
- NCT05401760
- Testing
- Group A :combined phacoaspiration and angle surgery, Group B : phacoaspiration only
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Cataract
Corneal Incisions With the IntraLase iFS Femtosecond Laser System
The IntraLase iFS femtosecond laser system can create corneal arcuate incisions for cataract surgery.
- Trial name
- NCT01713660
- Testing
- iFS Femtosecond Laser
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Pituitary Tumor, Optic Chiasm Disorder
Visual Outcome After Transsphenoidal Surgery for Pituitary Macroadenoma
Endoscopic endonasal transsphenoidal surgery is a procedure for the treatment of pituitary macroadenomas that cause visual impairment through optic chiasm compression.
- Trial name
- RetroADEN (NCT03363126)
- Testing
- Endonasal transsphenoidal pituitary tumor removal
- Volunteers
- 88 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Retinopathy of Prematurity
Bevacizumab Eliminates the Angiogenic Threat for Retinopathy of Prematurity
The purpose of this study was to determine the efficacy and additional advantages of intravitreal bevacizumab in the treatment of ROP for both Zone I and Zone II Posterior.
- Trial name
- BEAT-ROP (NCT00622726)
- Testing
- Bevacizumab, Conventional Laser for ROP
- Where
- 15 sites in United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center, Houston
Glaucoma, Cataract
The in Vivo Effect of Medical and Surgical Glaucoma Treatments on the Schlemm's Canal Micro-structure
The purpose of our current series of studies is to evaluate different glaucoma treatments in vivo effect on the conventional outflow pathway, and specifically on the Schlemm's canal (SC) anatomy using Enhanced Depth Imaging…
- Trial name
- NCT02807935
- Testing
- Optical coherence tomography imaging
- Where
- Israel
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Cataract
Nevanac 3-Month Safety Study With QID Dosing
The purpose of this study is to determine the safety of Nevanac 0.1% compared to Acular LS 0.4% and Vehicle in patients treated before cataract surgery and for approximately 90 days following surgery.
- Trial name
- NCT00332774
- Testing
- Nepafenac ophthalmic solution 0.1%, Ketorolac Tromethamine ophthalmic solution 0.4%, Nepafenac ophthalmic suspension vehicle
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Alcon Research
Cataract, Corneal Disease
Influence of Pupillary Behavior During Eye Surgery on Morphological and Functional Outcome
Pupillary movement during eye surgery can be a challenge for eye surgeons. Despite the risk of intraocular lens damage and malpositioning due to mechanical manipulation1, iris manipulation may lead to a significant elevation of…
- Conditions
- Cataract, Corneal Disease, Vitreous Disorder
- Trial name
- NCT06160960
- Testing
- OCT Scan, Video of pupil movement, video of toric lens
- Where
- Austria
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Klinikum Klagenfurt am Wörthersee
Cataract
Evaluation Of Bilateral Tecnis Multifocal Versus ReSTOR 3D Intraocular Lenses
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR intraocular lenses (IOLs) 6 months post cataract surgery.
- Trial name
- NCT01061918
- Testing
- Tecnis MF, ReSTOR
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Innovative Medical
Blepharoptosis
Comparison of Postoperative Pain With Two Different Types of Local Anesthesia in Surgery for a Drooping Eyelid
Conjunctival Mullerectomy is a well known procedure used to correct upper lid ptosis via a posterior approach. Patients who undergo this procedure are often given local anesthesia to alleviate intraoperative and postoperative…
- Trial name
- NCT01350024
- Testing
- Frontal nerve block with 2% lidocaine with 1:100,000 dilution of epinephrine, Subconjunctival injection of 2% lidocaine with 1:100,000 dilution with epinephrine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Miami
Eye Diseases
Protection of Corneal Epithelium Using Chitosan-N-acetylcysteine Eye Drops During and/or After Cataract Surgery
The aim of this study is to assess if treatment with Lacrimera® eye drops (Croma-Pharma GbmH, Leobendorf, Austria) during and/ or after cataract surgery has a positive effect on the ocular surface compared to control group.
- Trial name
- NCT05064189
- Testing
- Lacrimera
- Where
- Austria
- Volunteers
- 45 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Cataract
Assessment of Visual Function and Optics in Intraocular Lenses
The main objective of this research is to assess visual function and optical performance of CE marked, implanted intraocular lenses to understand the individual factors that affect their performance and how these may be improved…
- Trial name
- NCT01654159
- Testing
- Monofocal IOL, Multifocal IOL, Toric IOL
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Aston University
Cataract
Study of Efficacy and Safety of Vigadexa in Treating Inflammation and Infection Post-cataract Surgery
To demonstrate that the combination formulation of Moxifloxacin/Dexamethasone Eye Drop is effective and safe for the prevention of postoperative inflammation as a consequence of cataract extraction surgery.
- Trial name
- NCT00870103
- Testing
- Vigadexa (moxifloxacin 0.5% and dexamethasone 0.1%) eye drops
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Alcon Research
Pterygium
The Corneal and Conjunctiva Sensation Before and After Pterygium Surgeries
The purpose of this current study is to examine the sensation of the corneal and conjunctiva sensation before and after pterygium surgeries by Cochet bonnet esthesiometer and to examine epidemiological, clinical and imaging…
- Trial name
- NCT03314389
- Testing
- Cochet bonnet esthesiometer
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
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