Clinical trials: Ophthalmic Surgery
Age Related Cataract, Cataract
Effect of Trypan Blue on Corneal Endothelial Cell Count During Phacoemulsification
This randomized controlled trial evaluated the effect of trypan blue on corneal endothelial cell count in patients undergoing phacoemulsification for age-related cataract.
- Trial name
- NCT07735000
- Testing
- Trypan Blue, Phacoemulcification
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Postoperative Complications, Cataract
Safety and Efficacy Study of Topical Bromfenac Versus Placebo to Treat Ocular Inflammation After Cataract Surgery
The primary objective of this study was to investigate the efficacy of bromfenac sodium ophthalmic solution 0.09% for treatment of post-operative ocular inflammation in subjects who undergo cataract extraction and intraocular…
- Trial name
- NCT00198445
- Testing
- Bromfenac
- Where
- 39 sites in United States
- Volunteers
- 527 people
- Sponsor
- Bausch & Lomb Incorporated
Strabismus
Effect of Remifentanil on Postoperative Vomiting in Pediatric Strabismus Surgery
The purpose of this study is to compare the effect of remifentanil on postoperative vomiting in children undergoing strabismus surgery during sevoflurane anesthesia.
- Trial name
- NCT02455401
- Testing
- High dose remifentanil, Low dose remifentanil, No remifentanil
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Inje University
Macular Holes
Foveal Cone Outer Segment Resumption to Predict Visual Recovery After Macular Hole Surgery
Spectral domain optical coherence tomography (SD-OCT) was used to determine whether the repair of photoreceptor cone outer segment tips defect is significantly correlated with the visual outcomes after macular hole surgery.
- Trial name
- NCT01381965
- Testing
- Vitreous surgery for macular hole
- Where
- Japan
- Volunteers
- 72 people
- Sponsor
- Kyorin University
Dry Eye Disease (DED), Cataract (Post-operative Cataract Surgery Follow-up)
Effect of Dry Eye Disease on Accuracy of Intraocular Lens Power Calculation Before Phacoemulsification
This study aims to determine the effect of dry eye disease on intraocular lens power calculation and the postoperative refractive outcome.
- Trial name
- NCT07525336
- Testing
- dry eye disease optimization
- Volunteers
- 100 people
- Sponsor
- Assiut University
Ophthalmopathy
Effect Of Reusing the Operative Supplies On Cataract Surgery and Climate Change
Although postoperative infectious endophthalmitis and toxic anterior segment syndrome (TASS) rarely happen, they can threaten sight and are considered complications of intraocular and cataract surgery1.
- Trial name
- NCT06102265
- Testing
- sterilization
- Where
- 2 sites in Egypt
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cataract, Phacoemulsification
Intracameral Mydriasis Versus Topical Mydriasis in Cataract Surgery
The purpose is to determine if an intracameral solution of 0.2% tropicamide and 2% phenylephrine can dilate the pupil for cataract surgery as well as pre-operative topical 1% tropicamide and 5% phenylephrine.
- Conditions
- Cataract, Phacoemulsification, Mydriasis, Pseudoexfoliation Syndrome
- Trial name
- NCT00690222
- Testing
- Intracameral injection of mydriatic agent
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Nova Scotia Health Authority
Strabismus
Bilateral Recession or Unilateral Recession-Resection as Surgery for Infantile Esotropia
Infantile esotropia is corrected in most cases by bilateral recession of the medial rectus muscles (BR) or by unilateral recession of the medial rectus muscle and resection of the lateral rectus muscle (RR).
- Trial name
- NCT00304577
- Testing
- Bilateral recession, Unilateral recession and resection
- Where
- 12 sites in Germany, Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Myopia, Small-incision Lenticule Extraction (SMILE) Surgery
Potential Risk Factors and Predictive Model Construction of OBL During SMILE
To explore the prediction of OBL by deep learning model in SMILE surgery
- Trial name
- NCT06577012
- Testing
- Small incision lenticule extraction
- Where
- China
- Volunteers
- 4,678 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Strabismus
Peribulbar Block for Prevention of Oculocardiac Reflex
Strabismus is a common ophthalmic problem in Egypt that usually requires surgical correction. This surgery primarily aims to improve alignment of visual axis but may be required only for cosmetic reasons.
- Trial name
- NCT04549844
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Fayoum University Hospital
Glaucoma, Adherence
Effect of SMS Reminder and Free Eye Drops on Follow-up Adherence After Trabeculectomy Surgery in Rural China
The purpose of the study is to use a randomized controlled design to determine the impact of a SMS messaging associated with free eye drops intervention on the following outcomes among patients after trabeculectomy surgery in…
- Trial name
- NCT02328456
- Testing
- SMS and free eye drops
- Where
- China
- Volunteers
- 209 people
- Sponsor
- Congdon Nathan
Chronic Kidney Diseases, Eye Diseases
Smarter Care Virginia, Examining Low-Value Care in Virginia
Low-value care is defined as patient care that provides no net benefit to patients in specific clinical scenarios, and can cause patient harm.
- Conditions
- Chronic Kidney Diseases, Eye Diseases, Cardiac Disease, Surgery
- Trial name
- NCT04053335
- Testing
- Multicomponent Physician Performance Peer-Comparison Feedback Intervention
- Where
- United States
- Volunteers
- 5,000,000 people
- Sponsor
- University of California, Los Angeles
Open Angle Glaucoma, Cataract
Swedish Microinvasive Glaucoma Surgery Study (SMIGS)
The purpose of the study is to investigate the efficacy of Cataract Surgery as stand-alone compared to Cataract Surgery in combination with Kahook Dual Blade Glide goniotomy (KDB) or iStent Inject W Trabecular Microbypass Stent…
- Conditions
- Open Angle Glaucoma, Cataract, Kahook Dual Blade Glide, Istent Inject W
- Trial name
- SMIGS (NCT05035394)
- Testing
- Cataract surgery, KDB, Istent
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Umeå University
Endophthalmitis
Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery
Intracameral injection of 0.1% moxifloxacin solution after cataract surgery to prevent endophthalmitis
- Trial name
- NCT03244072
- Testing
- Moxifloxacin
- Where
- United States
- Volunteers
- 60,000 people, healthy volunteers welcome
- Sponsor
- Jason Ahee, M.D.
Efficacy, Complications
The Safety of Cataract Removal by Phacoemulsification Surgery in Patients Under Anti-aggregant and Coumadin Treatment
To assess the risks of intra- and postoperative bleeding tendency associated with cataract surgery by phacoemulsification in patients on coumadin and antiaggregant treatments. Design: Consecutive prospective study.
- Trial name
- NCT00564356
- Testing
- cataract surgery with phacoemulsification
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Sheba Medical Center
Dry Eye Disease (DED)
Evaluating Crosslinked Hyaluronate Canalicular Gel for the Treatment of DED in Patients Undergoing Cataract Surgery
To review how patients report using a hyaluronate crosslinked canalicular gel placed before cataract surgery
- Trial name
- LaReCa (NCT07155057)
- Testing
- Cross-Linked Hyaluronate Gel Prefilled Syringe 30 MG/3ML
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Hyperopia
Photorefractive Keratectomy (PRK) for Hyperopia After Radial Keratotomy
To assess the efficacy, predictability, stability and safety of corneal wavefront-guided photorefractive keratectomy (PRK) for correcting hyperopia and astigmatism after radial keratotomy (RK).
- Trial name
- NCT00917657
- Testing
- Photorefractive keratectomy
- Volunteers
- 36 people
- Sponsor
- University of Sao Paulo
Macula Hole
Macular Hole Surgery With Temporal Inverted Internal Limiting Membrane Flap (MARTIAL)
Since 1991, idiopathic macular holes (MH) can benefit from an effective treatment initially involving pars plana vitrectomy, stripping of epiretinal membranes and intraocular gas tamponade followed by facedown positioning.
- Trial name
- MARTIAL (NCT03287102)
- Testing
- Macular hole surgery
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Sleep Quality, Pain
Comparing the Efficacy of Earplugs and Eye Masks on Pain and Sleep Quality
Objective: To determine the superiority of earplugs and eye masks to each other and their efficacy in pain and sleep quality. Methods: The study was a three-arm randomised controlled trial.
- Conditions
- Sleep Quality, Pain, Intensive Care Medicine, Cardiac Surgery
- Trial name
- NCT07100002
- Testing
- Control Group, Earplug Group, Eye mask Group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Giresun University
Glaucoma, Open Angle Glaucoma
Long-term Safety and Performance of the ARGOS-SC Suprachoroidal Pressure Sensor System in Patients With Glaucoma Underwent Non-penetrating Glaucoma Surgery
The purpose of this study is to evaluate the long-term safety and performance of the ARGOS-SC system.
- Trial name
- NCT04773106
- Testing
- ARGOS-SC suprachoroidal pressure sensor
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 22 people
- Sponsor
- Implandata Ophthalmic Products GmbH
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