Clinical trials: Ophthalmic Surgery
Glaucoma, Congenital, Surgical Treatment
Inverted T Trabeculectomy Primary Congenital Glaucoma
This study aims to evaluate the safety and efficacy of novel Inverted T trabeculectomy in Primary Congenital Glaucoma (PCG). It enrolled 50 eyes of 25 children with PCG.
- Trial name
- Inverte T trab (NCT06837610)
- Testing
- Inverted T trabeculectomy
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Benha University
Blepharoptosis, Ptosis, Eyelid
Blepharoptosis in Indonesia: A 5-Year Multicenter Study on Characteristics and Surgical Evaluation
The goal of this observational study is to learn about blepharoptosis cases in national referral hospitals in Indonesia. The main questions it aims to answer are: How is the clinical characteristics, types, and surgical…
- Conditions
- Blepharoptosis, Ptosis, Eyelid, Characteristics Disease, Surgical Incision
- Trial name
- NCT06047418
- Testing
- Blepharoplasty
- Where
- Indonesia
- Volunteers
- 823 people
- Sponsor
- Universitas Indonesia
Ectropion
Comparison Between Two Surgical Methods for Eyelid Ectropion: Tarsal Strip Alone Versus Tarsal Strip With Punctoplasty (Three Snips With or Without Diamond-shaped Resection)
Ectropion of the eyelid can lead to skin retraction, stenosis of lacrimal point, chronic watering, visual discomfort or low visual acuity, mostly when it occurs with ectropion of lacrimal point.
- Trial name
- ECTROPALP (NCT02893813)
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Change in Sustained Attention
Attentional Capacity and Clinician Performance
Uncovering the distinct measurements and features that potentially exist in different levels of expertise when performing cardiology-based procedures.
- Trial name
- ACCP (NCT02928796)
- Testing
- Cognitive Stimulus
- Where
- Ireland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University College Cork
Eyelid Tumor
Mohs Surgery Combind With Cryotherapy for Eyelid Malignant Tumors.
This study aim to investigate whether the prognosis of eyelid malignant tumor is better treated with Mohs surgery combind with cryotherapy than Mohs surgery only.
- Trial name
- NCT05072327
- Testing
- Mohs surgery, cryotherapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Sun Yat-sen University
Optical Coherence Tomography, Refractive Errors
To Study the Effects of Refractive Surgery on OCT Measurements in the Eye
Corrective eye surgeries, such as Lasik, are widely used to correct focusing problems such as myopia, or nearsightedness. Often these patients develop other conditions like myopic maculopathy or glaucoma which require monitoring…
- Conditions
- Optical Coherence Tomography, Refractive Errors, Myopia
- Trial name
- NCT05856786
- Testing
- Optical coherence tomography
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Nebraska
Glaucoma
Reduction of Intraocular Pressure After I-stent By-pass Implantation in Eyes With Open Angle Glaucoma
Purpose of this study is to exam the hypotensive effectiveness of I-stent implantation depended on number of antiglaucoma eye drops at baseline.
- Trial name
- NCT03807869
- Testing
- combined glaucoma surgery
- Where
- Poland
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Left Ventricular Function, Cardiac Surgery
Artificial Intelligence Versus Anesthesiologist Visual Assessment of Ejection Fraction by Transesophageal Echocardiography During Cardiac Surgery
This prospective observational study evaluated the reliability of a general-purpose artificial intelligence application in estimating left ventricular ejection fraction from intraoperative transesophageal echocardiography images…
- Trial name
- NCT07841327
- Testing
- Artificial Intelligence Assessment of TEE Images
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Ain Shams University
Balanced Anesthesia, Adjuvants,Anesthesia
The Study of Different Sedative Medications in Monitored Anesthesia Care During Eye Surgery With Local Anesthesia
Due to the delicacy and long duration of the procedure, ophthalmic surgery put forward higher requirements to anesthesia management: 1.
- Trial name
- MAC (NCT04018703)
- Testing
- Dexmedetomidine, Midazolam
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Macular Holes, Retinal Detachment
Efficacy of Exercise Program for Facedown Posture-related Pain After Retinal Surgery
The purpose of this study is to evaluate the effects of a structured exercise program on musculoskeletal pain of patients in face-down posture after retinal surgery.
- Trial name
- NCT04535622
- Testing
- A structured exercise
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Samsung Medical Center
Primary Exotropia, Strabismus
Accommodative Changes After Medial Rectus Resection Versus Plication in Primary Exotropia
Exotropia is a type of eye misalignment in which one eye turns outward. In some patients, surgery is needed to improve eye alignment and binocular function.
- Conditions
- Primary Exotropia, Strabismus, Strabismus Surgery, Exotropia
- Trial name
- NCT07637253
- Testing
- Lateral Rectus Recession combined with Medial Rectus Resection, Lateral Rectus Recession combined with Medial Rectus Plication
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Dry Eye, Dry Eye Disease (DED)
Temporary Tear Duct Filling With Hyaluronic Acid Gel and Assessment of Dry Eye Disease (DED) After Bilateral Cataract Surgery
Dry eye disease can occur or worsen after cataract surgery and may cause ocular discomfort and reduced visual quality. Standard treatment commonly includes artificial tear eye drops, which provide temporary lubrication.
- Conditions
- Dry Eye, Dry Eye Disease (DED), Dry Eye Sensation After Cataract Surgery
- Trial name
- TANAMI (NCT07809022)
- Testing
- LACRIFILL® Canalicular Gel administration
- Where
- Austria
- Volunteers
- 25 people
- Sponsor
- Medical University of Vienna
Glaucoma
Impact of an Educational Video on Satisfaction After Glaucoma Surgery
Overall Objective: This study will assess whether an educational video is effective in increasing patient satisfaction with glaucoma surgery. 1.
- Trial name
- NCT03958929
- Testing
- Educational Video
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Sun Yat-sen University
Proliferative Diabetic Retinopathy
Compliance to Ophthalmic Follow-up Examinations and Surgical Outcome for Proliferative Diabetic Retinopathy
The relationship between the surgical outcome of vitreous surgery for proliferative diabetic retinopathy and the compliance to ophthalmic follow-up examinations was evaluated.
- Trial name
- NCT01307072
- Testing
- Vitrectomy
- Where
- Japan
- Volunteers
- 94 people
- Sponsor
- Kyorin University
Aphakia, Cataract
Clinical Study to Evaluate the Safety and Effectiveness of the RxSight Light Adjustable Lens (LAL) in Subjects With Prior Corneal Refractive Surgery
The primary objective of this study is to evaluate, for the visual correction of aphakia, the safety and effectiveness of the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) to reduce postoperative refractive…
- Trial name
- NCT03660865
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD), Control IOL
- Where
- 6 sites in United States
- Volunteers
- 105 people
- Sponsor
- RxSight, Inc.
Macular Hole
Visual Acuity and Optical Coherence Tomography One Year After ILM-flap Transposition
ILM-flap (internal limiting Membrane-flap) transposition is a new surgical option in repair of macular holes, therefore one year outcomes are needed to better evaluate that method.
- Trial name
- NCT03465865
- Testing
- optical coherence tomography
- Where
- Austria
- Volunteers
- 41 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Other Surgical Procedures
Effects of PEEP on Optic Nerve Sheath Diameter During Robot-Assisted Laparoscopic Prostatectomy
The investigators aim to investigate the effects of positive end-expiratory pressure ventilation on intracranial pressure assessed by sonographic optic nerve sheath diameter in patients undergoing robot-assisted laparoscopic…
- Trial name
- NCT02516566
- Testing
- PEEP
- Volunteers
- 38 people
- Sponsor
- Asan Medical Center
Cataract
Manipulating Temporal Expectations to Accelerate Recovery After Cataract Surgery
This study tested whether changing how quickly patients expect to heal after cataract surgery changes how quickly their vision recovers. Adults having cataract surgery in both eyes were randomly assigned to one of two groups.
- Trial name
- NCT07899112
- Testing
- Faster-timeline video and healing-attention surveys, Standard-timeline video and matched surveys
- Where
- 2 sites in United States
- Volunteers
- 147 people
- Sponsor
- Harvard University
Postoperative Ocular Inflammation, Postoperative Ocular Pain
A Phase 3 Study Evaluating the Safety and Efficacy of TRIESENCE® (Injectable Suspension) for the Treatment of Ocular Inflammation and Pain After Ophthalmic Surgery
This study is designed to evaluate the safety and efficacy of TRIESENCE® (triamcinolone acetonide injectable suspension) in patients undergoing ophthalmic procedures.
- Trial name
- NCT07832552
- Testing
- TRIESENCE (triamcinolone acetonide injectable suspension)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Harrow Inc
Macular Holes
To Evaluate the Therapeutic Efficacy of Hydrated Amniotic Membrane in Promoting Closure of Refractory Macular Holes.
To compare anatomic and functional results, and to evaluate postoperatively the healing process in 3 different techniques for the closure of the refractory macular holes (MH).
- Trial name
- NCT05396209
- Testing
- Hydrated Amniotic Membrane Plug, ILM filling, Conventional ILM peeling
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Oriental Neurosurgery Evidence-Based-Study Team