Clinical trials: Ophthalmic Surgery
Blindness
Do Blue-Blocking Lenses Block Blue Colour From Our Lives?
To measure colour vision in patients with a blue light filtering lens implant in one eye and non-tinted implant in the other eye (and compared this group with a control group with bilateral non-tinted implants) and to determine…
- Trial name
- NCT00403143
- Testing
- cataract surgery
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- London North West Healthcare NHS Trust
Cataract
High Resolution Immersion Ultrasound for iIOL Power Calculation
Assess is the additional use of high resolution immersion ultrasound measurements improve the refractive outcome after cataract surgery.
- Trial name
- NCT03749486
- Testing
- Cataract surgery
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Idiopathic Macula Hole
Clinical Observation of Technologic Application of No-touch Fluid-air Exchange in Surgery of Idiopathic Macula Hole
The purpose of this study is to observe the technologic application of no-touch fluid-air exchange in Surgery of Idiopathic Macula Hole.
- Trial name
- NCT02584062
- Testing
- no-touch fluid-air exchange, vitrectomy metrectomy and internal membrane peeling and gas tamponed
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Tianjin Medical University Eye Hospital
Diabetic Retinopathy
Study on Precision Treatment of Diabetic Retinopathy Macular Edema Guided by Real-time OCT During Operation
Select Proliferative Proliferative diabetic retinopathy(PDR) patients who are planning to undergo vitrectomy for informed notification. After obtaining informed consent, vitrectomy will be performed.
- Trial name
- NCT05138029
- Testing
- Ranibizumab Injection [Lucentis], Inner limiting membrane stripping, Dexamethasone intravitreal implant
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital of Nantong University
Rhegmatogenous Retinal Detachment, Hypotony Ocular
Ocular Hypotony and Refractive Predictability in RRD Surgery
This study evaluates how preoperative ocular hypotony (Goldmann IOP ≤ 7 mmHg) affects refractive predictability, axial length measurements, and visual outcomes in patients undergoing combined phacovitrectomy with silicone oil for…
- Trial name
- HYP-RRD (NCT07283614)
- Testing
- Combined Phacovitrectomy with Intraocular Lens Implantation and Silicone Oil Tamponade, Silicone Oil Removal
- Where
- Kazakhstan
- Volunteers
- 45 people
- Sponsor
- Kazakh Eye Research Institute
Bone Mineral Density, Primary Implant Stability
Digital Eye®-Assisted Bone Density Classification and Primary Dental Implant Stability.
Dental implants are used nowadays to replace extracted teeth. They provide a successful substitute for lost teeth. Accurate planning prior to implant placement is very important.
- Conditions
- Bone Mineral Density, Primary Implant Stability, Digital Eye Bone Density Assessment, Site-specific Drilling Protocol
- Trial name
- NCT07899606
- Testing
- R2GATE Digital EYE-Assisted Site-Specific Drilling Protocol, R2GATE® Digital EYE® Implant Planning Software, MEGA ISQ® - Implant Stability Measurement Device
- Where
- Jordan
- Volunteers
- 60 people
- Sponsor
- King Abdullah University Hospital
Glaucoma Open-Angle, Glaucoma Eye
INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register
The study is an observational analysis of patients' medical data recorded in a large-scale register, both retrospective (for patients operated and data recorded before 2018) and prospective (for data collected after 2018) in…
- Conditions
- Glaucoma Open-Angle, Glaucoma Eye, Glaucoma; Drugs, Glaucoma, Angle-Closure
- Trial name
- NCT04381611
- Where
- Switzerland
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Dr. Kaweh Mansouri
Patients With Highly Myopic Eyes
3D Visualization System for Vitreoretinal Diseases in Highly Myopic Eyes
To investigate the surgical outcomes and intraoperative parameters evaluation of 3D visualization system for vitreoretinal diseases in highly myopic eyes
- Trial name
- NCT05367193
- Testing
- pars plana vitrectomy, NGENUITY® 3D Visualization System (Alcon, TX, USA)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Cataract and IOL Surgery
Comparing Visual Outcomes in Matched Patients Receiving a Low Cylinder Power Toric IOL or a Non-toric IOL
The purpose of the study is to determine if visual function is improved with implantation of a low-cylinder toric intraocular lens, relative to a non-toric intraocular lens.
- Trial name
- NCT06717607
- Testing
- low cylinder toric IOL, non-toric IOL implantation
- Where
- Norway
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Ifocus Oyeklinikk
Cataract, Astigmatism
Femtosecond Laser Arcuate Keratotomy Versus Toric Intraocular Lens Implantation in Cataract Surgery
In modern cataract surgery, residual astigmatism continues to be one of the major factors influencing patients' visual quality and satisfaction.
- Trial name
- NCT06215807
- Testing
- Femtosecond laser arcuate keratotomy, Toric intraocular lens implantation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Retinal Detachment, Proliferative Vitreo-Retinopathy
Outcomes of Retinal Re-surgeries in Silicone Oil Filled Eyes
Anatomical and Visual outcomes of retinal re-surgeries done in silicone oil filled eyes
- Conditions
- Retinal Detachment, Proliferative Vitreo-Retinopathy, Proliferative Diabetic Retinopathy
- Trial name
- ReSxinSO (NCT06583798)
- Testing
- Resurgery In Silicone Oil Filled Eyes
- Where
- India
- Volunteers
- 33 people
- Sponsor
- Ahalia Foundation Eye Hospital
Cataract
Effect of the Timing of Cataract Surgery on Complications in Patients With Bilateral Congenital Cataracts
Congenital cataract is an important treatable cause of visual handicap in childhood throughout the world. Successful management of childhood cataract is dependent on individualized treatment strategies and rigorous postoperative…
- Trial name
- NCT02581046
- Testing
- Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 3month of the patients, Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 6 month of the patients, Subconjunctival dexamethasone and general anesthesia
- Where
- China
- Volunteers
- 61 people
- Sponsor
- Sun Yat-sen University
Cataract Surgery Deneyimi, Cataract Surgery
Katarak Surgery and Care
Although cataract surgery is an effective treatment method for improving visual function, it is important to evaluate the quality of life, daily living activities, independence level and psychosocial well-being of patients in the…
- Trial name
- NCT07807761
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Retinal Detachment, Epiretinal Membrane
PIONEER: Intraoperative and Perioperative OCT Study
OCT provides high-resolution information regarding the anatomic structure of the tissues of the eye in a 2-dimensional and 3-dimensional view. Much of this information is not able to be recognized by a clinician.
- Conditions
- Retinal Detachment, Epiretinal Membrane, Macular Hole, Fuchs Endothelial Dystrophy
- Trial name
- PIONEER (NCT02423161)
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Cataract and IOL Surgery
Development of Optical Biometer
The Helioscope (Cassini Technologies B.V.) is a novel device under development that aims at combining LED-based corneal topography and SS-OCT to provide accurate and fast measurements of both the corneal shape and the ocular…
- Trial name
- CH-0203 (NCT07325162)
- Testing
- New Investigational Optical Biometer (Device), Comparator Device A (Cassini Ambient), omparator Device B (Argos)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cassini Technologies
Anxiety, Pain
Evaluation of Anxiolysis and Pain Associated With Retrobulbar Eye Block for Cataract Surgery : Melatonin Versus Gabapentin
Principle goals of sedation for eye surgery are to provide patient comfort and to allow the patient to stay calm during both retrobulbar injection and surgery.
- Trial name
- NCT01200641
- Testing
- Melatonin, Gabapentin
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Qazvin University Of Medical Sciences
Open Angle Glaucoma, Cataract
OMNI in Open-angle Glaucoma Treatment
This single-center, prospective study will assess safety and effectiveness of 360 degree viscodilation followed by up to 360 degree trabeculotomy used in patients with early or moderate open-angle glaucoma in a real-world setting…
- Conditions
- Open Angle Glaucoma, Cataract, Eye Diseases, Glaucoma
- Trial name
- NCT04503356
- Testing
- OMNI as a standalone procedure, OMNI combined with cataract surgery
- Where
- Poland
- Volunteers
- 17 people
- Sponsor
- Centre of Postgraduate Medical Education
Cataract Senile, Astigmatism
Accuracy of Topography Guided Automatic Marking of the Intraocular Lens (IOL) -Axis
In cataract surgery, the opaque lens is replaced by an artificial intraocular lens. The procedure also allows for correction of an refractive error such as myopia, hyperopia or astigmatism.
- Trial name
- NCT05750862
- Testing
- Marking of the intended axis of IOL-Implantation manually with an ink and marking device on the surface of the eye
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Frank Bochmann
Refractive Disorders
Visual and Optics Impact of Refractive Surgery
Refractive surgery includes interventions to correct refractive errors, using a medical device such as a laser or an implant (intraocular lenses) or surgical instruments.
- Trial name
- CRIVO (NCT02889588)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Macular Hole
Fundus Autofluorescence After Macular Hole Surgery
Funds autofluorescence (FAF) indicates hyper fluorescence at the macular hole in the patients with macular hole. Investigators investigate the association between FAF and visual acuity, recovery of foveal microstructure, and FAF…
- Trial name
- NCT02628262
- Testing
- Vitrectomy with internal limiting membrane removal and gas tamponade
- Where
- Japan
- Volunteers
- 27 people
- Sponsor
- Makoto Inoue
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