Clinical trials: Ophthalmic Surgery
Cataract
Evaluation Of Bilateral Tecnis Multifocal Versus ReSTOR 3D Intraocular Lenses
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR intraocular lenses (IOLs) 6 months post cataract surgery.
- Trial name
- NCT01061918
- Testing
- Tecnis MF, ReSTOR
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Innovative Medical
Laparoscopic Surgery
The Impact of Anesthesia and Positioning on Cerebral Blood Flow and Pressure in Patients Undergoing Laparoscopic Surgery
The aim of this observational study was to understand the effect of ReverseTrendelenburg position, Trendelenburg position on intracranial pressure and carotid blood flow in patients undergoing laparoscopic surgery.
- Trial name
- NCT06669689
- Testing
- operating position, pneumoperitoneum
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xiaguang Duan
Dacryocystitis, Dacryocystitis; Chronic
Examination of Lacrimal Sac and Nasal Mucosa Preparations Taken in Dacryocystorhinostomy Surgery of Patients With Nasolacrimal Duct Obstruction and Comparison of Clinical Groups With Each Other
The goal of this observational study is to investigate etiology and pathogenesis of nasolacrimal duct obstruction and dacryocystitis in different adult clinic groups.
- Conditions
- Dacryocystitis, Dacryocystitis; Chronic, Dacryocystorhinostomy, Epiphora
- Trial name
- NCT06810089
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Uludag University
Ocular Inflammation
Comparison Study of ISV-303 to Durasite Vehicle in Cataract Surgery Subjects
The purpose of this study is to evaluate the ocular safety, tolerability and efficacy of topical administration of ISV-303 compared with Durasite Vehicle.
- Trial name
- NCT01808547
- Testing
- ISV-303, DuraSite Vehicle
- Volunteers
- 268 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Cataract, Inflammation
Evaluation of BOL-303242-X Versus Vehicle for the Treatment of Inflammation Following Cataract Surgery
This clinical study is being conducted to identify the most effective drug concentration and dose frequency of BOL-303242-X (Mapracorat) ophthalmic suspension, for the treatment of inflammation following cataract surgery.
- Trial name
- NCT00905450
- Testing
- BOL-303242-X, Vehicle for BOL-303242-X
- Where
- United States
- Volunteers
- 415 people
- Sponsor
- Bausch & Lomb Incorporated
Vitreous Detachment
Comparison of Propofol Target Controlled Infusion (TCI) and Sevoflurane
This study was an experimental, single-blinded, randomized controlled trial that aimed to compare recovery time between TCI propofol and sevoflurane.
- Trial name
- NCT04865991
- Testing
- TCI Propofol, Sevoflurane
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Cataract
Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
- Trial name
- NCT00704418
- Testing
- Bromfenac
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Bausch & Lomb Incorporated
Primary Open Angle Glaucoma, Low Tension Glaucoma
Assessing Ocular Hemodynamic Response to Surgical Intervention in Glaucoma
The purpose of this study is to assess how surgical interventions in glaucoma affect 24-hour intraocular pressure, 24-hour ocular perfusion pressure, optic nerve blood flow, and retinal oxygen saturation.
- Conditions
- Primary Open Angle Glaucoma, Low Tension Glaucoma, Cataract, Ocular Hypertension
- Trial name
- NCT02891317
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of North Carolina, Chapel Hill
Cataract
To Analyze the Economics of Office-based (OBS) Versus Ambulatory Surgery Center (ASC)-Based Cataract Surgery.
To analyze the economics of office-based (OBS) versus ambulatory surgery center (ASC)-based cataract surgery.
- Trial name
- OBSvsASC (NCT07554391)
- Testing
- Office based surgery
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Rush Eye Associates
Cataract, Anterior Chamber Inflammation
Iontophoretic Delivery of EGP-437 in Patients Who Have Undergone Cataract Surgery
Phase 2b trial evaluating the safety and efficacy of EGP-437, versus placebo using the EyeGate® II Drug Delivery System (EGDS) in patients having undergone cataract surgery with implantation of a monofocal posterior chamber…
- Conditions
- Cataract, Anterior Chamber Inflammation, Pain, Postoperative
- Trial name
- NCT03180255
- Testing
- Dexamethasone phosphate
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Cataract
Efficacy of Dextenza Insert in Upper vs Lower Punctum Following Cataract Surgery With PCIOL.
To assess the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert in the operating room following cataract surgery/intraocular lens implant (IOL) with or without iStent/Hydrus/Goniotomy…
- Trial name
- DEXTENZA (NCT05372315)
- Testing
- Dextenza 0.4Mg Ophthalmic Insert
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Iworks Laser and Vision Center
Cataract
Clinical Application Comparison of Two Femtosecond Laser Systems
The goal of this clinical trial is to compare the perioperative parameters of femtosecond laser-assisted cataract surgery (FLACS) using two laser systems.
- Trial name
- NCT06754358
- Testing
- LenSx, Z8
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Glaucoma
24-hour IOP Fluctuation Profile Recorded With SENSIMED Triggerfish in Primary Open-angle Glaucoma (POAG) Patients After Cataract Surgery
The purpose of this study is to determine the relationship between intraocular pressure (IOP) fluctuations of glaucoma patients as recorded with an IOP-sensing contact lens (SENSIMED Triggerfish®), during two 24-hour periods…
- Trial name
- NCT01495299
- Testing
- Phacoemulsification with implantation of intraocular lens (CE-IOL) SENSIMED Triggerfish
- Where
- United States
- Sponsor
- University of California, San Diego
Cataract, Endophthalmitis
The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery
The study investigates whether placing an antibiotic inside the eye at the end of cataract surgery in children will reduce the amount of fibrin formation (fibrin formation can block the pupil and reduce vision).
- Trial name
- NCT00730938
- Testing
- cefuroxime
- Where
- Kenya
- Volunteers
- 45 people
- Sponsor
- Presbyterian Church East Africa Kikuyu Hospital
Anxiety
Cranial Electro Therapy Stimulation in Reducing Perioperative Anxiety
Cranial electro stimulation (CES) provides safe, adequate, side-effect free sedation without excessive drowsiness in preoperative settings.
- Trial name
- NCT00928772
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Oklahoma
Eye Cyclorotation Degree, Pupil Shift
Evaluation of Position-induced Cyclorotation Between Wavefront Measurement and Refractive Surgery by the Iris Registration Method
Cyclorotation of eyes may be affected by motion and orientation of the head and body. An automated alignment method with the technique of iris recognition was used to assess the amount and orientation of position-induced…
- Trial name
- NCT00943163
- Where
- Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Myopia, Myopic Astigmatism
A Study With Technolas® TENEO 317 Model 2 Excimer Laser to Treat Participants With Myopia or Myopic Astigmatism
The primary objective of this study is to collect safety and effectiveness data for the Technolas Teneo 317 Model 2 excimer laser for LASIK correction in participants with myopia and myopic astigmatism.
- Trial name
- NCT04111757
- Testing
- Technolas® TENEO 317 Model 2
- Where
- 10 sites in United States
- Volunteers
- 168 people
- Sponsor
- Bausch & Lomb Incorporated
NPDR - Non Proliferative Diabetic Retinopathy, Diabetes Mellitus, Type 2
Characterization of Retinal Disease Progression in Eyes With Non Proliferative Diabetic Retinopathy in Diabetes Type 2 Using Non-invasive Procedures (CHART)
To identify biomarkers, obtained using non-invasive procedures, that can predict disease progression and progression to sight-threatening stages of the disease and to characterize the retinal changes that occur in Non…
- Conditions
- NPDR - Non Proliferative Diabetic Retinopathy, Diabetes Mellitus, Type 2, Retinal Disease
- Trial name
- CHART (NCT04636307)
- Testing
- Biomarkers
- Where
- 5 sites in France, Italy and 1 more
- Volunteers
- 202 people
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
Glaucoma Open-Angle Primary, Glaucoma
Comparing Preoperative Injection of Mitomycin-C vs. Intraoperative Injection of Mitomycin-C vs. Topical Application of Mitomycin-C (Conventional Use) in Trabeculectomy
In this Pilot explorative study, the investigators are going to estimate and compare the outcomes of three different delivery methods of MMC for Trabeculectomy: a subconjunctival injection of MMC 0.002% at the site of future…
- Conditions
- Glaucoma Open-Angle Primary, Glaucoma, Open Angle Glaucoma, Glaucoma, Open-Angle
- Trial name
- NCT03875911
- Testing
- Mitomycin C
- Where
- 4 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Dacryocystitis
Analgesic Efficacy of Pre-operative Oral Pregabalin in Dacryocystorhinostomy Surgery
This study is conducted to evaluate the effects of preoperative oral pregabalin on postoperative pain and analgesic requirements in patients undergoing DCR surgery.
- Trial name
- NCT05455944
- Testing
- Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sameh Fathy
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