Clinical trials: Ophthalmic Surgery
Emergence Agitation, Remimazolam
Effect of Remimazolam vs Sevoflurane Anesthesia on Incidence of Emergence Agitation and Complications in Children Undergoing Ophthalmic Surgery
As a novel ultra-short-acting benzodiazepines drugs, Remimazolam has been accepted for induction and maintenance of clinical anesthesia.
- Conditions
- Emergence Agitation, Remimazolam, Sevoflurane, Pediatric Ophthalmic Surgery
- Trial name
- NCT05527314
- Testing
- Remimazolam, Sevoflurane, Fentanyl
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Age Related Cataract, Cataract
Effect of Trypan Blue on Corneal Endothelial Cell Count During Phacoemulsification
This randomized controlled trial evaluated the effect of trypan blue on corneal endothelial cell count in patients undergoing phacoemulsification for age-related cataract.
- Trial name
- NCT07735000
- Testing
- Trypan Blue, Phacoemulcification
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Pterygium
Efficacy and Safety of Sub-tenon Ranibizumab for Recurrent Pterygia
Ranibizumab, an effective antineovascular drug, will be studied for safety and efficacy in pterygium, a neovascular disorder of the ocular surface.
- Trial name
- NCT01169909
- Testing
- Ranibizumab
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Cataract Surgery, Patient Satisfaction
Evaluation of Duration of Anesthesia and Patient Satisfaction After Retrobulbar Block Applied in Cataract Surgery
It is aimed to determine patient satisfaction (pain assessment during and after the operation) and the initial and total anesthesia durations of eye lid and globe anesthesia after administration of local anesthetic solution only…
- Conditions
- Cataract Surgery, Patient Satisfaction, Akinesia, Anesthesia, Local
- Trial name
- NCT04178200
- Testing
- Lidocaine 2% Injectable Solution 0.75 ml, Bupivacaine Hcl 0.5% Inj 0.75 ml, Lidocaine 2% Injectable Solution 1.5 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Develi Devlet Hastanesi
Cataract, Vitreous Detachment
Effect on the Vitreous of the Not Complicated Surgery of the Cataract to the Emmetropic Patient
This study evaluates the association between surgery of the cataract and posterior vitreous detachment, in the emmetropic patient, by comparing eyes operated with eyes not operated in the same group of patients
- Trial name
- VITRECAT (NCT02783209)
- Testing
- Cataract surgery
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Vitreous Detachment, Cataract (Post-operative Cataract Surgery Follow-up)
Evaluation of Vitreous Modifications After Cataract Surgery
This study aims to evaluate changes in vitreous structure and the vitreoretinal interface following cataract surgery using spectral-domain optical coherence tomography (OCT).
- Trial name
- VitCat (NCT07816887)
- Testing
- cataract surgery
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University of Trieste
Extended Depth-of-Focus Intraocular Lens, Cataract
Visual and Patient-Reported Outcomes After Bilateral Non-Diffractive EDOF IOL Implantation
This study evaluates visual outcomes and patient-reported satisfaction following bilateral cataract surgery using a non-diffractive extended depth-of-focus (EDOF) intraocular lens (AcrySof IQ Vivity).
- Conditions
- Extended Depth-of-Focus Intraocular Lens, Cataract, Visual Acuity
- Trial name
- EDOF-Visual (NCT07457216)
- Testing
- AcrySof IQ Vivity EDOF Intraocular Lens
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University
Vitrectomy
A Study to Evaluate the Safety and Performance of the Vista Probe for Vitrectomy Surgery
This is a prospective, single-arm, non-comparative, open-label, monocular, post approval study to assess safety and device performance of the Vista Vitrectomy Probe during vitrectomy surgery.
- Trial name
- NCT05689333
- Testing
- Vista Vitrectomy Probe
- Where
- 4 sites in United States
- Volunteers
- 32 people
- Sponsor
- VISTA Ophthalmics
Postoperative Ocular Inflammation, Postoperative Ocular Pain
A Phase 3 Study Evaluating the Safety and Efficacy of TRIESENCE® (Injectable Suspension) for the Treatment of Ocular Inflammation and Pain After Ophthalmic Surgery
This study is designed to evaluate the safety and efficacy of TRIESENCE® (triamcinolone acetonide injectable suspension) in patients undergoing ophthalmic procedures.
- Trial name
- NCT07832552
- Testing
- TRIESENCE (triamcinolone acetonide injectable suspension)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Harrow Inc
Retinopathy
Anesthesia for Retinopathy of Prematurity
Premature infants experience more respiratory problems after surgical procedures. The investigators aimed to compare general anesthesia with sedation on the need for post-operative mechanical ventilation in infants undergoing…
- Trial name
- NCT01955135
- Testing
- Ketamine, Sevoflurane, propofol
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Cataract
High-Definition 3D Visualization System for Ophthalmic Surgery
To validate a high-definition (HD) three-dimensional (3D) visualization system in cataract surgery
- Trial name
- NCT02194543
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Dry Eye
The Effect Of Lifitegrast On Refractive Accuracy And Symptoms In Dry Eye Patients Undergoing Cataract Surgery
To determine if Xiidra® lifitegrast plays a role in the refractive accuracy when administered to patients preoperatively who are scheduled for cataract surgery and have a tear break up time (TBUT) ≤ 10 seconds and central corneal…
- Trial name
- NCT03866629
- Testing
- Lifitegrast
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- MDbackline, LLC
Dry Eye Syndromes
Clinical Efficacy of Intense Pulsed Light(IPL) Procedure in Dry Eye Patient
Clinical efficacy of Intense Pulsed Light(IPL) procedure in dry eye patients with meibomian gland dysfunction prior to cataract surgery.
- Trial name
- NCT04391907
- Testing
- IPL
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Squint
Intravenous Versus Peribulbar Dexmedetomidine for Strabismus Surgery in Adults
Using various adjuvants has become a trend in regional anesthesia practice to improve the quality of anesthesia and prolong postoperative analgesia.
- Trial name
- NCT05215158
- Testing
- Dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 46 people
- Sponsor
- Aswan University Hospital
Cataract, High Myopia
Evaluation of Cataract Surgery Outcome
The purpose of this study is to evaluate the visual outcome of the cataract surgery, including best uncorrected and corrected visual acuity, spherical equivalent, wavefront aberration and other measurements.
- Trial name
- NCT02182921
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Evidence Based Cataract Study Group
Cataract
Identification of Clinical, Biometrical and Operatory Factors Related to Pain During Cataract Surgery
Adults who undergo cataract surgery will be questioned after surgery about the eventual pain they experienced, about their health history, personal treatment.
- Trial name
- NCT04353843
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Montpellier
Cataract
Effect of Minimising Ultrasound Power to 1% During Cataract Surgery on Corneal Endothelium.
Coaxial microincision cataract surgery using 1% ultrasound is not inferior to standard coaxial microincision cataract surgery in patients of grade 0.1-6.0 immature senile cataract in terms of corneal endothelial safety.
- Trial name
- OCTOPUS (NCT01259349)
- Testing
- one percent ultrasound power in CMICS, 40 percent ultrasound power in CMICS
- Where
- India
- Volunteers
- 72 people
- Sponsor
- Dr. Ram Manohar Lohia Hospital
Keratoconus
Prevelance of Keratoconus
Keratoconus is a degenerative disease entity characterized by conical shape ectasia of the cornea. progressive conical deformation of the cornea leads to substantial astigmatism.
- Trial name
- NCT04092426
- Testing
- opthalmologic examination
- Volunteers
- 300 people
- Sponsor
- Assiut University
Proliferative Diabetic Retinopathy
Compliance to Ophthalmic Follow-up Examinations and Surgical Outcome for Proliferative Diabetic Retinopathy
The relationship between the surgical outcome of vitreous surgery for proliferative diabetic retinopathy and the compliance to ophthalmic follow-up examinations was evaluated.
- Trial name
- NCT01307072
- Testing
- Vitrectomy
- Where
- Japan
- Volunteers
- 94 people
- Sponsor
- Kyorin University
Cataract
Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
- Trial name
- NCT00703781
- Testing
- bromfenac ophthalmic solution
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Bausch & Lomb Incorporated
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