Clinical trials: Opioid Use, completed
Opioid-use Disorder, Pregnancy Related
Quantitative Sensory Psychophysical Correlates of Pain in Pregnant Women With OUD
This is a prospective observational case-control study comparing quantitative sensory testing data preformed during the third trimester of pregnancy and within 24 hours postpartum in women on medication-assisted treatment for…
- Trial name
- Q-PRONTO (NCT04888962)
- Testing
- OUD
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Opioid Use, Opioid-use Disorder
Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder: Supplement to COMPUTE 2.0
This study integrates the Mental Health Research Network (MHRN) suicide risk models into Opioid Wizard, an electronic health record (EHR) clinical decision support (CDS) to identify and treat patients at high risk of opioid use…
- Conditions
- Opioid Use, Opioid-use Disorder, Suicide
- Trial name
- NCT04939727
- Testing
- OUD-CDS + Suicide Risk Model associated CDS
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- HealthPartners Institute
Postoperative Pain, Narcotic Use
Postoperative Opt-In Narcotic Treatment Study
pills go unused, generating waste and leaving an opportunity for misuse and abuse. In a recent study, researchers let patients choose what medications to go home with after surgery.
- Conditions
- Postoperative Pain, Narcotic Use, Analgesia, Endocrine Surgery
- Trial name
- POINT (NCT04710069)
- Testing
- POINT
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Opioid-use Disorder, Anxiety
MINDFUL-OBOT: Effect of Mindfulness on Opioid Use and Anxiety During Primary Care Buprenorphine Treatment
The goal of this pilot study is to test the Mindful Recovery OBOT Care Continuum (M-ROCC) model in primary care office-based opioid treatment (OBOT).
- Conditions
- Opioid-use Disorder, Anxiety, Depression, Stress Related Disorder
- Trial name
- NCT03798431
- Testing
- M-ROCC
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Cambridge Health Alliance
Opioid Use Disorder
Contingency Management to Improve Medication for Opioid Use Disorder Continuation After the Emergency Department
Project Summary The goal of this pilot clinical trial is to assess contingency management (CM) for increasing attendance at outpatient clinics after Medication for Opioid Use Disorder (MOUD) prescription and clinic referral…
- Trial name
- CM+ED+MOUD (NCT07129902)
- Testing
- Contingency Management, Usual care as prescribed by the ED physicians
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Vermont
Femur Fracture, Tibial Fractures
Postoperative Pain Management in Patients Undergoing Intramedullary Nail Fixation After Tibia and Femoral Fractures
The purpose of this trial is to determine whether oral acetaminophen and intravenous ketorolac are viable alternatives to opioid medication regimens for the pain management of patients with tibial and femoral shaft fractures…
- Trial name
- NCT04761302
- Testing
- Intravenous ketorolac and oral acetaminophen, Intravenous morphine and oral oxycodone
- Where
- Puerto Rico
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Opiate Addiction
Onsite Buprenorphine Treatment at Syringe Exchange Programs
This trial will recruit syringe exchange participants with opioid use disorder in New York City and test whether starting buprenorphine treatment at the syringe exchange program is more effective than referral to a community…
- Trial name
- O-BMT (NCT03150173)
- Testing
- Onsite treatment, Enhanced referral, Buprenorphine
- Where
- 3 sites in United States
- Volunteers
- 97 people
- Sponsor
- Montefiore Medical Center
Opioid Use, Pain, Postoperative
Outcome of Multimodal Anesthesia Bern
In the context of the ongoing opioid crisis in the USA and Europe, reducing perioperative opioid use is a growing priority. Multimodal anesthesia (MMA) offers a patient-centered alternative to opioid-free anesthesia, combining…
- Conditions
- Opioid Use, Pain, Postoperative, Postoperative Complications, Postoperative Nausea
- Trial name
- NCT06985069
- Testing
- General anesthesia applying multimodal anesthesia, General anesthesia using conventional opioid-based regimen
- Where
- Switzerland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Opioid Use Disorder
Computerized Anxiety Sensitivity Treatment for Opioid Use Disorders
The primary aim of the current project is to test the acceptability and feasibility of a computerized intervention, titled Computerized Anxiety Sensitivity Treatment (CAST), delivered to Veterans seeking treatment for an opioid…
- Trial name
- CAST-O (NCT03944850)
- Testing
- Computerized Anxiety Sensitivity Treatment
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Southeast Louisiana Veterans Health Care System
Opioid Use, Pain, Postoperative
ESP Catheter Vs Single Shot ESP for Open Heart Surgery in Infants
Post operative pain after open heart surgery is still a main concern; current multimodal analgesia modalities have shown good efficacy for postoperative pain at rest, without reaching full pain relief.
- Conditions
- Opioid Use, Pain, Postoperative, Quality of Life
- Trial name
- ESPINFANT (NCT03593642)
- Testing
- Continuous infusion of ropivacain in ESP catheter, Continuous infusion of Iso Saline in ESP catheter
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Vinmec Healthcare System
Opioid Use
Characterizing the Association Between Preoperative Depressive Symptoms and Opioid Use/Misuse After Surgery
This observational study aims to characterize the relationship between preoperative depressive symptoms and opioid use/ misuse after surgery using a perioperative learning health care system.
- Trial name
- NCT05412342
- Where
- 2 sites in United States
- Volunteers
- 718 people
- Sponsor
- Stanford University
Telehealth at the Library, Control Group
"Bupe by the Book": Testing Library Telehealth With Unstably Housed Persons With Opioid Use Disorder
Public libraries nationwide are facing an on-premise opioid overdose crisis. Many persons with opioid use disorder (OUD) remained unhoused and profoundly hard to reach.
- Trial name
- BBB (NCT05872386)
- Testing
- Library Telehealth with Buprenorphine Provider, Treatment-as-Usual Control group
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Opioid-Related Disorders
Youth Opioid Recovery Support: Improving Care Systems
Opioid addiction, also referred to as opioid use disorder, among young people is a growing health concern for patients and their families.
- Trial name
- YORS (NCT04015115)
- Testing
- Youth Opioid Recovery Support service model
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Opioid-use Disorder, Stress Related Disorder
Effect of Mindfulness on Opioid Use and Anxiety During Primary Care Buprenorphine Treatment (R33 Phase)
This will be a randomized controlled trial (RCT) designed to compare live-online Mindful Recovery Opioid Care Continuum (M-ROCC) groups with a live-online control group on the primary outcome of number of biochemically confirmed…
- Conditions
- Opioid-use Disorder, Stress Related Disorder, Anxiety, Pain Interference
- Trial name
- Mindful-OBOT (NCT04278586)
- Testing
- Live-Online M-ROCC, Live-Online Control
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Cambridge Health Alliance
Opioid-Related Disorders
Improving Health and Employment Outcomes Through Workplace Opioid Policies
Evaluate the feasibility of implementing workplace opioid guidelines in the construction trades; define and collect measures of implementation and efficacy.
- Trial name
- NCT05387408
- Testing
- Best Practice Health and Employment Opioid-related Policies
- Where
- United States
- Volunteers
- 4,939 people
- Sponsor
- Washington University School of Medicine
Chronic Pain, Opioid Use
Slow Opioid Tapering Pilot Study of Patients Using Chronic Opioid Therapy
The purpose of this study is to find out if patients who have been taking a stable dose of opioids for chronic pain would experience any worsening pain, quality of life and functioning, as well as symptoms of depression and…
- Trial name
- NCT05297396
- Testing
- Slow Tapering of Chronic Opioid Therapy
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Mayo Clinic
HIV Prevention Program, Opioid-use Disorder
Testing of the Integrated Rapid Access to HIV Prevention Program for People Who Inject Drugs Program
This is a pilot study of an integrated rapid access HIV prevention program for People who inject drugs (PWID) called iRaPID. The program incorporates same-day access to Pre-exposure Prophylaxis (PrEP) and Opioid Agonist Therapy…
- Trial name
- iRaPID (NCT04531670)
- Testing
- iRaPID, Standard of Care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Connecticut
Opioid Use Disorder, Pregnancy Related
Transdermal Patch for BupRenorphine Induction DurinG PrEgnancy (Patch BRIDGE)
The goal of this clinical trial is to compare buprenorphine patch for induction (starting) of buprenorphine in pregnant patients with opioid use disorder. The main questions it aims to answer are: 1.
- Conditions
- Opioid Use Disorder, Pregnancy Related, Pregnancy, High Risk, Pregnancy Complications
- Trial name
- Patch BRIDGE (NCT05790252)
- Testing
- Buprenorphine Transdermal Matrix Patch
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Washington University School of Medicine
Opioid Use, Opioid Prescribing
Variation in Opioid Prescribing and Use for Acute Pain in Diverse Populations
This study will characterize patient pain and opioid use after an initial opioid prescription for acute pain.
- Trial name
- NCT04509115
- Testing
- Short-acting opioid prescription for acute pain
- Where
- 5 sites in United States
- Volunteers
- 1,709 people
- Sponsor
- Yale University