Clinical trials: Opioid-Induced Disorders
Substance-Related Disorders, Opioid-Related Disorders
Incentives to Decrease Opioid Use - Pilot
The purpose of this study is to address two key questions in the literature on incentives for substance use. The first question is whether it is more effective to directly incentivize the outcome of interest - drug abstinence …
- Conditions
- Substance-Related Disorders, Opioid-Related Disorders, Behavior Therapy
- Trial name
- NCT04235582
- Testing
- App + Inputs Contingency Management, App + Outcomes Contingency Management
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Wake Forest University Health Sciences
Opioid-Induced Bowel Dysfunction
Opioid-induced Bowel Dysfunction: Pivotal Assessment of Lubiprostone
The primary purpose of this study is to evaluate the efficacy and safety of lubiprostone administration in patients with Opioid-induced Bowel Dysfunction.
- Trial name
- OPAL (NCT00595946)
- Testing
- Lubiprostone
- Where
- 95 sites in United States, Canada
- Volunteers
- 439 people
- Sponsor
- Sucampo Pharma Americas, LLC
Opioid-related Disorders
Abuse Liability of Suboxone Versus Subutex
The study is designed to compare the abuse liabilities of intravenous buprenorphine and buprenorphine/naloxone in individuals who are physically dependent on sublingual buprenorphine.
- Trial name
- NCT00710385
- Testing
- Heroin, Naloxone, Low Bup Dose
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Opioid-use Disorder, Recidivism
Fostering MAT Use in Justice Populations
The grant will test two timely and successful evidence-based implementation practices, NIATx Coaching and ECHO, with jail/community-based healthcare providers to increase medication assisted treatment (MAT) use with justice…
- Trial name
- NCT04363320
- Testing
- NIATx Coaching, ECHO
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of Wisconsin, Madison
Opioid Use, Opioid-use Disorder
Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder: Supplement to COMPUTE 2.0
This study integrates the Mental Health Research Network (MHRN) suicide risk models into Opioid Wizard, an electronic health record (EHR) clinical decision support (CDS) to identify and treat patients at high risk of opioid use…
- Conditions
- Opioid Use, Opioid-use Disorder, Suicide
- Trial name
- NCT04939727
- Testing
- OUD-CDS + Suicide Risk Model associated CDS
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- HealthPartners Institute
Opiate Addiction
Onsite Buprenorphine Treatment at Syringe Exchange Programs
This trial will recruit syringe exchange participants with opioid use disorder in New York City and test whether starting buprenorphine treatment at the syringe exchange program is more effective than referral to a community…
- Trial name
- O-BMT (NCT03150173)
- Testing
- Onsite treatment, Enhanced referral, Buprenorphine
- Where
- 3 sites in United States
- Volunteers
- 97 people
- Sponsor
- Montefiore Medical Center
Opioid Dependency
Transdermal Electroacupuncture for Opioid Detoxification
This single-blind, randomized clinical trial tests whether electroacupuncture, provided as an adjunctive treatment, improves outcomes among patients receiving inpatient opioid detoxification from opioids.
- Trial name
- NCT00742170
- Testing
- Electroacupuncture
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Mclean Hospital
Opioid-use Disorder, Stress Related Disorder
Effect of Mindfulness on Opioid Use and Anxiety During Primary Care Buprenorphine Treatment (R33 Phase)
This will be a randomized controlled trial (RCT) designed to compare live-online Mindful Recovery Opioid Care Continuum (M-ROCC) groups with a live-online control group on the primary outcome of number of biochemically confirmed…
- Conditions
- Opioid-use Disorder, Stress Related Disorder, Anxiety, Pain Interference
- Trial name
- Mindful-OBOT (NCT04278586)
- Testing
- Live-Online M-ROCC, Live-Online Control
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Cambridge Health Alliance
Opioid-Related Disorders
Improving Health and Employment Outcomes Through Workplace Opioid Policies
Evaluate the feasibility of implementing workplace opioid guidelines in the construction trades; define and collect measures of implementation and efficacy.
- Trial name
- NCT05387408
- Testing
- Best Practice Health and Employment Opioid-related Policies
- Where
- United States
- Volunteers
- 4,939 people
- Sponsor
- Washington University School of Medicine