Clinical trials: Optical Coherence Tomography of Retina
Optical Coherence Tomography (OCT) of the Retina
Low Cost OCT for Point of Care
The purpose of this study is to compare the performance of a prototype optical coherence tomography (OCT) machine with currently available high resolution OCT machines.
- Trial name
- NCT03323307
- Testing
- OCT imaging
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Duke University
Erectile Dysfunction Following Radical Prostatectomy
Study of Retinal and Choriocapillary Vascular Changes in Patients Undergoing Tadalafil 20mg
This study evaluates the retinal and choriocapillary vascular features in patients under the effects of Tadalafil 20mg using optical coherence tomography angiography.
- Trial name
- NCT04164355
- Testing
- Tadalafil 20 MG
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Federico II University
Macula Abnormality
Comparison of Repeatability Between SS and SD-OCT for Measuring Retinal Thickness in Various Retinal Diseases
Comparison of intradevice repeatability of thickness measurements for macular area in the eyes with normal and various retinal diseases using SS-OCT and SD-OCT
- Trial name
- NCT03438903
- Testing
- Repeat exams of OCT device
- Where
- South Korea
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Exudative Age-related Macular Degeneration
Evaluation of Retinal and Vascular Features in Macular Degeneration After Intravitreal Injections of Bevacizumab
This study evaluates the retinal and vascular features in patients with macular degeneration under the effects of Bevacizumab intravitreal injections using optical coherence tomography and optical coherence tomography angiography.
- Trial name
- NCT04138420
- Testing
- Bevacizumab Injection
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Federico II University
Strabismus, Retinal Thickening
Choroidal and Retinal Thickness Following Strabismus Surgery
Prospective study, conducted at Tanta University Ophthalmology Department Measurement of macular and choroidal thickness before and after strabismus surgery
- Trial name
- NCT04285177
- Testing
- Strabismus surgery
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Diabetic Retinopathy
Study on Precision Treatment of Diabetic Retinopathy Macular Edema Guided by Real-time OCT During Operation
Select Proliferative Proliferative diabetic retinopathy(PDR) patients who are planning to undergo vitrectomy for informed notification. After obtaining informed consent, vitrectomy will be performed.
- Trial name
- NCT05138029
- Testing
- Ranibizumab Injection [Lucentis], Inner limiting membrane stripping, Dexamethasone intravitreal implant
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital of Nantong University
Macular Edema, CNV
Evaluation of Retinal Structure With High Resolution Optical Coherence Tomography (OCT)
Comparison of different OCT instruments to assess retinal thickness, correlation to fluorescein angiography, and visual outcome after therapy with anti-VEGF therapy
- Trial name
- NCT00564291
- Testing
- Examination with an OCT device
- Where
- 2 sites in Switzerland
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Sebastian Wolf
Alzheimer Disease, Alzheimer Dementia
Multimodal Retinal Imaging in the Detection and Follow-up of Alzheimer's Disease
Because of a shared ontogenic origin, the retina displays similarities to the brain and spinal cord in terms of anatomy, functionality, response to insult, and immunology.
- Conditions
- Alzheimer Disease, Alzheimer Dementia, Mild Cognitive Impairment, Dementia
- Trial name
- RetAD (NCT03466177)
- Testing
- Non-invasive, multimodal retinal imaging
- Where
- Belgium
- Volunteers
- 320 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Macular Degeneration
The Optical Coherence Tomography in Age-Related Macular Degeneration Study: The OCT in AMD Study
The Optical Coherence Tomography (OCT) is a non-contact, non invasive method to examine the retina by providing cross-sectional scans through the retina.
- Trial name
- NCT00531141
- Testing
- examination only
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Hypertensive Retinopathy
Non-invasive Measurement of Retinal Blood Flow Based on Vessel Analysis and Fourier Domain Optical Coherence Tomography in Patients With Hypertensive Retinopathy
Recently, a new and sophisticated method for assessment of retinal blood flow and retinal blood flow velocity profiles has become available.
- Trial name
- NCT01753648
- Testing
- Dynamic Vessel Analyzer, FDOCT, Ocular perfusion pressure
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Retinal Pathology
Prospective Comparison of Cirrus Versus Stratus Ocular Coherence Tomography for Different Retinal Pathology.
Ocular Coherence Tomography (OCT) is a non-invasive ophthalmologic test that uses reflected, unheated, non-concentrated visible light in order to scan and provide a 2-dimensional topographic analysis of the retina and optic…
- Trial name
- NCT00731458
- Testing
- Optical coherance tomography ( Cirrus; Stratus)
- Volunteers
- 60 people
- Sponsor
- University of Chicago
Neovascular Age-related Macular Degeneration
Development of an Optimal Algorithm for the Management of Patients With Retinal Pigment Epithelium Detachment in Neovascular Age-related Macular Degeneration Using Artificial Intelligence
The study involves the development of an algorithm for predicting anatomical and functional results of therapy with angiogenesis inhibitors in patients with retinal pigment epithelium detachments in neovascular age-related…
- Trial name
- NCT05208931
- Testing
- Anti-vascular endothelial growth factor therapy
- Where
- Russia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Macular Disease
Evaluation of Retinal Microstructure Detected With Intraoperative Optical Coherence Tomography During Vitrectomy
We evaluate the intraoperative optical coherence tomographic (OCT) images of eyes with idiopathic macular hole (MH) or lamellar macular hole whether the intraoperative OCT findings will affect postoperative visual outcome.
- Trial name
- NCT03244007
- Testing
- Vitrectomy
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Kyorin University
Giant Cell Arteritis, Visual Impairment
Visual Involvement in Giant Cell Arteritis
This observational study aims to enhance the description of the different ways Giant Cell Arteritis (GCA) affects vision. The latest technology and knowledge are used to improve how we diagnose and predict patient outcomes.
- Conditions
- Giant Cell Arteritis, Visual Impairment, Central Retinal Artery Occlusion, Anterior Ischemic Optic Neuropathy
- Trial name
- Visu-GCA (NCT06500728)
- Testing
- Fluorescein and Indocyanine green Angiography, High-resolution Optical Coherence Tomography, Angio-Optical Coherence Tomography
- Where
- Italy
- Volunteers
- 762 people
- Sponsor
- ASST Fatebenefratelli Sacco
Migraine
Retinal Nerve Fiber Layer Thickness Changes in Migraine: A Meta-Analysis of Case-control Studies
Optical coherence tomography (OCT) is a non-invasive retinal imaging technology that can provide high-resolution cross-sectional images of the peripapillary retinal nerve fiber layer (RNFL) and measure its thickness.
- Trial name
- NCT02196532
- Testing
- Device: Optical coherence tomography
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yifan Feng
Epiretinal Membrane
Visual Acuity and Optical Coherence Tomography One Year After Peeling of Epiretinal Membranes
Improvement in visual acuity and retinal anatomy one year after surgery is assessed and compared to data preoperative and 3 months after surgery
- Trial name
- NCT03583632
- Testing
- visual acuity testing, optical coherence tomography
- Where
- Austria
- Volunteers
- 75 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Healthy
Optical Coherence Tomography (OCT) Normative Data Collection Study
This study is being initiated to create a normal database including measures of optic nerve head (ONH), peripapillary retinal nerve fiber layer (RNFL), and macula using the Heidelberg Spectralis OCT device.
- Trial name
- S-2013-3 (NCT02014688)
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG)
Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
The goal of this clinical trial is to learn whether a high-dose vitamin B3 supplement called nicotinamide can protect retinal nerve cells in adults with primary open-angle glaucoma (POAG) who are already receiving standard…
- Trial name
- NADIR (NCT07808333)
- Testing
- Nicotinamide, Standard Glaucoma Therapy
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Chicago
Retinal Vasculitis
Optical Coherence Tomography (OCT) in Retinal Vasculitis
Retinal vasculitis is a sight-threatening inflammation that involves the blood vessels of the retina, the tissue that lines the inside of the eye.
- Trial name
- NCT01998464
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Oregon Health and Science University
Optic Neuritis, Multiple Sclerosis
Neuroprotection With Phenytoin in Optic Neuritis
Optic neuritis is caused by inflammation of the optic nerve and causes loss of vision in the affected eye. It is often associated with multiple sclerosis.
- Trial name
- NCT01451593
- Testing
- Phenytoin
- Where
- 2 sites in United Kingdom
- Volunteers
- 92 people
- Sponsor
- University College, London