Clinical trials: Oral Candidiasis
Denture Stomatitis
The Effectiveness of Palatal Brushing on Denture Stomatitis
Denture stomatitis (DS) is an oral biofilm associated inflammatory disease of the palatal mucosa. It is the most prevalent oral disease and the main indicator of poor oral health among denture wearers, affecting one-third of all…
- Trial name
- NCT02686632
- Testing
- Palatal brushing
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Candidiasis, Oral, Stomatitis, Denture
Efficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal Antiseptic
The purpose of this study is to evaluate the efficacy and safety of propolis on the treatment of oral candidiasis, more specifically denture stomatitis.
- Trial name
- NCT02818803
- Testing
- Propolis, Miconazole
- Where
- 2 sites in Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Oral Lichen Planus, Candida Infection
The Use of Probiotics in Patients With Symptomatic Oral Lichen Planus
The aim is to investigate the effect of probiotic bacteria on symptoms and clinical manifestations in patients with oral lichen planus (OLP).
- Trial name
- NCT01743690
- Testing
- Probiotic lactobacilli reuteri, Nystatin, fluocinolone
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- University of Copenhagen
Oral Candidiasis, Denture Stomatitis
Efficacy of Slow Release Clotrimazole Varnish Treating Denture Stomatitis Comparing to Traditional Treatment of Troches
Background: Oral candidiasis is most frequently found among the elderly .It is accompanied with oral pain, irritation, burning sensation.
- Trial name
- NCT00835029
- Testing
- Clotrimazole varnish, Clotrimazole troches
- Where
- Israel
- Volunteers
- 13 people
- Sponsor
- Hadassah Medical Organization
Candidiasis, Oral
Comparative Trial of Micafungin Versus Fluconazole for Treating Esophageal Candidiasis
To determine the efficacy and safety of IV Micafungin versus IV Fluconazole in the treatment of patients with Esophageal Candidiasis
- Trial name
- NCT00666185
- Testing
- Micafungin, Fluconazole
- Where
- 37 sites in Brazil, Peru and 1 more
- Volunteers
- 523 people
- Sponsor
- Astellas Pharma Inc
Candidiasis, Oral
Trial of Two Dosing Regimens of Micafungin Versus Caspofungin for the Treatment of Esophageal Candidiasis
To determine the efficacy and safety of daily doses of IV micafungin versus IV caspofungin for the treatment of esophageal candidiasis
- Trial name
- NCT00665639
- Testing
- micafungin, caspofungin
- Where
- 31 sites in Argentina, Brazil and 2 more
- Volunteers
- 454 people
- Sponsor
- Astellas Pharma Inc
Dental Plaque, Denture Stomatitis
Efficacy of a Propolis-based Denture Cleanser
The purpose of this study is to assess if a propolis solution is able to remove plaque and kill microbes from complete dentures.
- Conditions
- Dental Plaque, Denture Stomatitis, Oral Candidiasis, Oral Hygiene
- Trial name
- NCT01237782
- Testing
- Denture soaking solution, Saline solution
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Raphael Freitas de Souza
Dental Plaque, Denture Stomatitis
Experimental Denture Pastes
This trial aims to evaluate the efficacy of three experimental dentifrices to remove denture biofilm. Complete denture wearers will be instructed to brush their dentures with a specific toothbrush and four compositions: (1) A…
- Conditions
- Dental Plaque, Denture Stomatitis, Oral Candidiasis, Oral Hygiene
- Trial name
- NCT01237795
- Testing
- Dentifrice
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Raphael Freitas de Souza
Candidiasis, Oral
Clotrimazole vs. Mycelex® in Patients With Human Insufficiency Virus (HIV) Infection for the Treatment of Oropharyngeal Candidiasis
The objectives of this study are to compare the efficacy and safety of Roxane's clotrimazole troches vs. Mycelex troches in HIV positive patients with oropharyngeal candidiasis, where this condition has been diagnosed by clinical…
- Trial name
- NCT02184351
- Testing
- Roxanes's clotrimazole troches, Mycelex® troches
- Volunteers
- 187 people
- Sponsor
- Boehringer Ingelheim
Denture Stomatitis
The Effect of Palatal Brushing on Denture Stomatitis
Palatal brushing has several advantages including removal of debris and stimulation of blood flow and saliva, which may help to prevent or treat oral diseases, such as denture-related stomatitis in complete denture wearers.
- Trial name
- NCT01643876
- Testing
- Palatal brushing
- Where
- 2 sites in Brazil, Canada
- Volunteers
- 48 people
- Sponsor
- Université de Montréal
Oral Candidiasis
Acidophilus for the Treatment and Prevention of Oral Candidiasis in Patients Undergoing Radiation Therapy
The purpose of this study is to determine the effectiveness of using acidophilus to treat oral candidiasis (thrush) caused by radiation therapy to the head and neck region. This study will conducted in two parts.
- Trial name
- NCT00768794
- Testing
- Acidophilus, Acidolphilus
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Summa Health System
Oral Candida, Breastfeeding
Oral Candida in Infants and Dietary Type
This is an observational, non-randomised trial to evaluate the effect of dietary type on infants oral candida colonization the investigators evaluated 90 infants in 1-24 months (45 breastfeeding and 45 bottle feeding infants) who…
- Conditions
- Oral Candida, Breastfeeding, Bottle Feeding
- Trial name
- NCT01438983
- Where
- Iran
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shahid Sadoughi University of Medical Sciences and Health Services
Candidiasis, Oral, Thrush
Novel Rinse to Treat in Oral Candidiasis in Cancer Patients
The purpose of the study is to evaluate the efficacy of Iocide oral rinse as a treatment for Oral Candidiasis in any patient including but not limited to patients receiving radiation therapy or who have previously received…
- Conditions
- Candidiasis, Oral, Thrush, Candidiasis
- Trial name
- NCT00612963
- Testing
- Frio Oral Rinse
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Biomedical Development Corporation
Oral Candidiasis
Phase 2B Dose-Ranging Study of PAC113 Mouthrinse in HIV Seropositive Individuals With Oral Candidiasis
The purpose of this study is to determine the optimal dose of PAC113 mouthrinse for treatment of oral candidiasis in HIV seropositive patients.
- Trial name
- NCT00659971
- Testing
- PAC113
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- Pacgen Biopharmaceuticals Corporation
Candidiasis, Oral, Eating Disorders
The Effect of Oral Candidiasis on the Speech Production, Feeding Skills, and Self-Concept of Children and Adolescents With Symptomatic HIV Infection
The main objectives of this study are: 1) to determine whether various levels of severity of oral candidiasis (thrush) in the child are associated with different levels of speech production, feeding skills, and self-concept, and…
- Conditions
- Candidiasis, Oral, Eating Disorders, HIV Infections, Speech Disorders
- Trial name
- NCT00001448
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)
Acquired Immunodeficiency Syndrome, Candidiasis
Fluconazole Prophylaxis of Thrush in AIDS
This is a placebo-controlled trial of intermittent fluconazole prophylaxis (200 mg orally three times a week) in the prevention of thrush.
- Conditions
- Acquired Immunodeficiency Syndrome, Candidiasis, Oral Candidiasis
- Trial name
- NCT00001542
- Testing
- fluconazole
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Candidiasis, Oral, Gastrointestinal Diseases
A Randomized, Double-Blind, Placebo Controlled Trial Evaluating the Impact of Nystatin on the Development of Oral Irritation in Patients Receiving High Dose Intravenous Interleukin-2
In patients who are receiving intravenous high dose Interleukin-2, patients will be randomized into two groups: group one will receive nystatin swish and swallow immediately before initiation of IL-2, and the second group will…
- Conditions
- Candidiasis, Oral, Gastrointestinal Diseases, Stomatitis
- Trial name
- NCT00001812
- Testing
- Nystatin
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- National Cancer Institute (NCI)
Candidiasis, Oral
A Comparison of Gentian Violet (GV) Mouth Washes, Nystatin, and Ketoconazole Tabs in Treating Oropharyngeal Candidiasis
In resource constrained societies and where HIV is a problem, oral thrush causes significant morbidity. In adults, ketoconazole is used and sometimes oral nystatin.
- Trial name
- NCT00128323
- Testing
- Gentian violet 1% solution, Gentian violet 0.00165% solution, Nystatin solution
- Where
- Malawi
- Volunteers
- 558 people
- Sponsor
- Kamuzu University of Health Sciences
Candidiasis, Esophageal, HIV Infections
Evaluation of Amphotericin B in the Treatment of Biopsy Proven Candida Esophagitis in Immunocompromised Patients
To determine the appropriate duration of amphotericin B therapy for Candida esophagitis. To compare the effectiveness of two different amphotericin B doses in the treatment of biopsy-proven Candida esophagitis.
- Trial name
- NCT00002041
- Testing
- Amphotericin B
- Where
- United States
- Sponsor
- Bristol-Myers Squibb
Candidiasis, Oral, HIV Infections
Nystatin Pastilles for the Prevention of Oral Candidiasis in Patients With AIDS or ARC
To determine a safe, effective, and convenient dosing schedule for nystatin pastilles in the prevention of oral candidiasis in patients with AIDS or AIDS related complex (ARC) (group III or IV, CDC classification).
- Trial name
- NCT00002057
- Testing
- Nystatin
- Where
- 2 sites in United States
- Sponsor
- Bristol-Myers Squibb