Clinical trials: Oral Glucose Tolerance Test
Contraception
The Effect of Hormonal Contraceptives on Androgens and Glucose Metabolism
The impact of different administration routes of hormonal contraceptives on androgen secretion, glucose metabolism and inflammation. A prospective randomized trial.
- Trial name
- NCT01087879
- Testing
- Desogestrel-Ethinyl Estradiol contraceptive pill, Etonogestrel-Ethinyl Estradiol vaginal ring, Norelgestromin-Ethinyl Estradiol contraceptive patch
- Where
- Finland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Oral Glucose Tolerance
The Effects of Aspartame on Appetite, Body Composition and Oral Glucose Tolerance
Assess the impact of chronic use of aspartame on glycemia, appetite and body composition.
- Trial name
- NCT02999321
- Testing
- aspartame, water
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Purdue University
Acromegaly
Reproducibility and Utility of OGTT in Acromegaly
Prospective study of reproducibility and utility of growth hormone inhibition by oral glucose tolerance test for the diagnosis of acromegaly, in acromegalic and non-acromegalic subjects, with a randomized double-blind crossover…
- Trial name
- ACROTEST (NCT04066569)
- Testing
- Performed 2 diagnostic tests (2 OGTT tests with 75g of Glucose)
- Where
- France
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Childhood Obesity
Leipzig Childhood Obesity Study
The aim of this study is to identify polymorphisms that make children and adolescents more prone to obesity and metabolic dysfunction, as well as to identify biomarkers that are linked to causes and consequences of obesity.
- Trial name
- NCT04491344
- Where
- Germany
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Obesity
Longitudinal Assessment of Cardiovascular and Metabolic Parameters in Obese and Lean Children
The investigators hypothesize that cardiovascular and metabolic alterations due to obesity already manifest at childhood age. To identify these alterations and risk factors, the investigators have established a cohort of 177…
- Trial name
- NCT01605123
- Where
- 2 sites in Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Metabolic Diseases
Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Oral Glucose Tolerance Test
The goal of this study is to understand how exogenous kisspeptin affects metabolism by evaluating responses to an oral glucose tolerance test
- Trial name
- NCT04958109
- Testing
- Oral Glucose Tolerance Test, Kisspeptin
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Type 2 Diabetes Mellitus (T2DM), Chronic Pancreatitis
Exocrine-Endocrine Pancreatic Crosstalk: Precision Pathways to Reframe Diabetes Pathophysiology
The EXPAND study is a prospective observational study designed to investigate the biological mechanisms underlying the heterogeneity of type 2 diabetes and related metabolic disorders.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Chronic Pancreatitis, Prediabetes, Pancreatic Neoplasms
- Trial name
- EXPAND (NCT07670871)
- Volunteers
- 440 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Prediabetes
Blood Sugar Take Care and Glucose Metabolism
This prospective international clinical trial is a two-arm, double-blind, randomized, placebo-controlled, parallel-group, multicenter study. 112 prediabetic subjects will be randomized to Blood Sugar Take Care or placebo.
- Trial name
- NCT01554020
- Testing
- Blood Sugar Take Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- NewChapter, Inc.
Diabetes Mellitus, Type 2
The Proportion of Patients With Non-diagnosed Diabetes Type 2
The aims of the study are to determine the prevalence of diabetes in subgroups of the population with certain characteristics (age, gender, socioeconomic status, geographical area of residence), to estimate the proportion of…
- Trial name
- Sadkorna (NCT04230382)
- Testing
- Diagnosis of diabetes (OGTT)
- Where
- Slovenia
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Type 2 Diabetes Mellitus
Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus
Investigate the acute effect of the steviol glycoside, rebaudioside A, on the glucose excursion during an oral glucose tolerance test in 30 patients with type 2 diabetes mellitus.
- Trial name
- AREBAG (NCT03510624)
- Testing
- Rebaudioside A
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Heathly Volunteers
Role of a Mitochondrial Receptor in Blood Sugar Regulation
The goal of this clinical trial is to learn whether a single dose of XBD173, a medicine that binds to a protein called the 18 kiloDalton Translocator Protein (TSPO), affects how the body processes glucose in healthy volunteers…
- Trial name
- G-TSPO (NCT07682233)
- Testing
- XBD173
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Cystic Fibrosis
Comparing Laboratory Blood Glucose Results With HemoCue Glucose 201 RT
There are very few studies comparing the accuracy, sensitivity and specificity of HemoCue glucose 201 RT system with the laboratory gold standard.
- Trial name
- CFRD (NCT01883037)
- Testing
- Blood glucose results
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Ketones, Dietary Supplements
Exogenous Ketones and Glucose Tolerance
The ketone body beta-hydroxybutyrate is produced during prolonged fasting or when endogenous carbohydrate stores are depleted and can be used as an alternative fuel source.
- Trial name
- NCT03461068
- Testing
- Ketone monoester
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Diabetes, Gestational
DIAgnosing GDM usiNg Oral Sugar InStead
The purpose of this study is to compare the positive and negative effects of Dex4® tablets, as an alternative form of fast acting carbohydrate, compared to the current standard diagnostic test, glucose beverage.
- Trial name
- DIAGNOSIS (NCT05115188)
- Testing
- Dex4/ dextrose, Glucose beverage
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Gestational Diabetes, Pregnancy
Oral Glucose Tolerance Testing After Gestational Diabetes
This is an observation study of women with gestational diabetes. Subjects recruited undergo immediate postpartum diabetic screening prior to discharge. Post-partum screening for overt diabetes is repeated 6-12 weeks postpartum.
- Conditions
- Gestational Diabetes, Pregnancy, Obesity
- Trial name
- NCT02082301
- Where
- 2 sites in United States
- Volunteers
- 118 people
- Sponsor
- MetroHealth Medical Center
Healthy Subjects
Nutrigenomics Investigation of the Body's Metabolic Response to 2 Different Meal Challenges
The purpose of this study is to investigate the biological response to a metabolic stress, given in the form of a high carbohydrate or fat meal in normal weight, overweight and obese individuals and to further explore these…
- Trial name
- MECHE (NCT01172951)
- Testing
- Oral glucose tolerance test, Oral lipid tolerance test
- Where
- 2 sites in Ireland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Iron Overload, Hemoglobinopathies
Comparing CGM and OGTT in Relation to Iron Overload Detected by Pancreas T2* MRI in High-Risk Hematology Group
A prospective, observational, comparative study with no intervention.The objective of the study to compare the efficiency of detecting glycemic abnormalities using Continuous Glucose Monitoring (CGMs) versus Oral Glucose…
- Conditions
- Iron Overload, Hemoglobinopathies, Lymphoma, Acute Lymphoblastic Leukemia
- Trial name
- CGMs (NCT03141398)
- Testing
- Continuous Glucose Monitoring (CGM), Oral Glucose Tolerance Test (OGTT), T2* MRI of the Pancreas
- Sponsor
- Hamad Medical Corporation
Prolactinoma
Metabolic Outcomes in Patients With Prolactinomas Under Dopamine Agonist Treatment
This randomized, active-controlled, parallel-arm, single-blind trial is to compare the effects of Dopamine agonists (DA) therapy targeting different established treatment strategies on glucose metabolism assessed by an oral…
- Trial name
- ProBOLIC (NCT07045935)
- Testing
- Cabergoline (Dopamine Agonist)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Diabetes, Impaired Glucose Tolerance (IGT)
A Survey on the Rate of Glucose Intolerance in Hong Kong Chinese
Hypothesis: There is a high rate of glucose intolerance among Hong Kong Chinese. The investigators plan to screen Hong Kong Chinese from the community with oral glucose tolerance test (OGTT).
- Conditions
- Diabetes, Impaired Glucose Tolerance (IGT), Impaired Fasting Glucose (IFG), Glucose Intolerance
- Trial name
- NCT00787215
- Testing
- observational: no treatment involved
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Idiopathic Ketotic Hypoglycemia
A Glucometabolic Evaluation of Patients With Idiopathic Ketotic Hypoglycemia
The project will evaluate 1) the postprandial metabolism and 2) continuous glucose levels in subjects diagnosed with Idiopathic Ketotic Hypoglycemia (IKH)) and healthy control subjects.
- Trial name
- IKH_MetEx (NCT05310292)
- Testing
- Oral glucose tolerance test, Mixed meal test
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen