Clinical trials: Oral Health Related Quality of Life
Partial-edentulism, Temporary Partial Denture
Evaluation of Digital 3D Printed Temporary Removable Partial Denture.
This study aims to compare oral health-related quality of life and retention between digitally- fabricated temporary flexible RDPs and conventionally-fabricated temporary flexible RDPs.
- Conditions
- Partial-edentulism, Temporary Partial Denture, 3D Printing, Oral Health Related Quality of Life
- Trial name
- NCT06106243
- Testing
- The conventional heat pressing temporary flexible maxillary removable partial denture, 3D-printed and digitally designed temporary flexible maxillary removable partial denture
- Where
- Egypt
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cairo University
Quality of Life, Down Syndrome
OHRQoL and Parental Perception in a Group of Children and Adolescents With Down Syndrome: A Cross
The aim of the study is to evaluate Oral Health related quality of life of children and adolescents with down syndrome and Parental Perception, knowledge and Attitude on oral health conditions of children and adolescents with…
- Conditions
- Quality of Life, Down Syndrome, Oral Health
- Trial name
- NCT04394221
- Where
- Egypt
- Volunteers
- 194 people
- Sponsor
- Cairo University
Patient Comfort, Malocclusion
Comparison of Patient-Reported Comfort Between Two Clear Aligner Trimming-Line Designs: A Split-Mouth Study
The trimming-line design of clear aligners (supragingival versus juxtagingival) is a routine clinical decision whose influence on patient-reported comfort has not been established; available evidence on aligner comfort derives…
- Conditions
- Patient Comfort, Malocclusion, Oral Health
- Trial name
- COMFORT-ALIGN (NCT07660809)
- Testing
- Supragingival trimming-line design, Juxtagingival festooned trimming-line design
- Where
- Romania
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Malocclusion
A RCT to Compare OHRQoL Outcome for SLB and CB
The objective of this prospective study is to compare these two treatments (conventional brackets v.s. self-ligating brackets) in malocclusion to determine which treatment will provide the better oral health related quality of…
- Trial name
- NCT02084277
- Testing
- Self-ligating brackets (SLB), Conventional brackets (CB)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Mackay Memorial Hospital
Edentulism, Edentulism Complete
Masticatory Efficiency, Bite Force, and Patient-Reported Outcomes in Patients Rehabilitated With Complete and Partial Dentures Supported by Teeth, Mini-Implants, or Conventional Implants
This study aims to evaluate masticatory efficiency, bite force, and patient-reported outcomes in edentulous and partially edentulous patients rehabilitated with different removable prosthodontic treatment modalities.
- Conditions
- Edentulism, Edentulism Complete, Partial Edentulism, Complete Dentures
- Trial name
- IMPROSTREHAB (NCT07639112)
- Where
- 2 sites in Croatia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Edentulism
The Impact of Palatal Rugae Addition to Complete Dentures on Patients' Satisfaction and Oral Health Related Quality of Life
In conventional maxillary complete dentures, the palatal surface is typically smooth and polished, lacking the natural anatomy of the palatal rugae.
- Trial name
- Palatal rugae (NCT07034079)
- Testing
- complete dentures
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Partially Edentulous Mandible
Polyetheretherketone vs Cobalt-chromium Telescopic Removable Partial Denture in Kennedy Class I Patients Regarding Oral Health Related Quality of Life
Dentistry is a rapidly progressing field with innumerable advances taking place on a day to day basis. The application of newer technologies and materials has advanced the specialty of prosthodontics and the services rendered to…
- Trial name
- NCT03771248
- Testing
- peek telescopic partial denture
- Volunteers
- 20 people
- Sponsor
- Cairo University
Periodontitis, Probiotic
Patient-Reported Probiotic Use During Periodontal Therapy in Periodontitis
Most previous studies have evaluated standardized probiotic regimens as adjuncts to NSPT (Ausenda et al., 2023; Hardan et al., 2022; Mauriello et al., 2025).
- Conditions
- Periodontitis, Probiotic, Oral Hygiene, Oral Health, Periodontal Therapy
- Trial name
- NCT07619040
- Testing
- non surgical periodontal therapy
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Medipol University
Periodontal Diseases, Caries Dentalis
Dental and Periodontal Health Levels of Dental and Medical Faculty Students
The aim of this observational study is to investigate the relationship between periodontal and dental health status and oral health-related quality of life among dental and medical faculty students.
- Trial name
- NCT07425860
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Orthodontic Appliances, Removable, Orthodontic Appliance Complication
Microbial Adherence, Surface Roughness, Effectiveness and Impact on Patients Between Conventional and 3D Printed Twin Block Appliances
The Twin Block appliance is a removable orthodontic appliance that is used to help correct a backward positioned lower jaw in growing children.
- Conditions
- Orthodontic Appliances, Removable, Orthodontic Appliance Complication, Class II Malocclusion, Division 1
- Trial name
- NCT06944860
- Testing
- Conventional TBA, 3D TBA
- Where
- Malaysia
- Volunteers
- 32 people
- Sponsor
- University of Malaya
Complete Edentulism, Partial Denture
AI-authored Video for Denture Care: an RCT
To assess the effectiveness of AI-based educational videos in improving patient-reported oral health outcomes.
- Conditions
- Complete Edentulism, Partial Denture, Partial Edentulism in the Maxilla or in the Mandible
- Trial name
- NCT07184320
- Testing
- AI-Based Video Education on Denture Care, Conventional Oral Health Instruction
- Where
- United Arab Emirates
- Volunteers
- 50 people
- Sponsor
- Sherif Aly Sadek
Hemophilia A and B, Periodontitis
Effect of Non-Surgical Periodontal Treatment on Oral Health in Hemophilia Patients
This study aimed to evaluate the effect of non-surgical periodontal treatment (NSPT) on oral health-related quality of life in patients with hemophilia using the Oral Health Impact Profile-14 (OHIP-14) questionnaire.
- Conditions
- Hemophilia A and B, Periodontitis, Hemophilia
- Trial name
- NCT07691437
- Testing
- Non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Mucositis, Quality of Life
Effect of Hawthorn Vinegar, Black Mulberry Syrup and Green Tea on Oral Mucositis
In this context, this study investigated the quality of life related to oral mucositis and oral health in patients with DM using hawthorn vinegar, black mulberry syrup and green tea.
- Trial name
- Oral Mucositis (NCT06481254)
- Testing
- Hawthorn Vinegar Group, Black Mulberry Syrup Group, Green Tea Group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Quality of Life, Self Efficacy
Oral Health Education Interventions Among Seniors
The study aims to assess the efficacy of an oral health education group based activity versus an individual based oral health education activity in terms of changes in oral health related quality of life (OHRQoL), self-efficacy…
- Conditions
- Quality of Life, Self Efficacy, Knowledge
- Trial name
- NCT03301714
- Testing
- Oral Health Education
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Temple University
Edentulous Jaw, Quality of Life
Impact of the Use of New Complete Denture on the Oral Health Related to Quality of Life (OHRQoL)
The aim of this project was to evaluate the impact before and after (3, 6, 9, and 12 months) of oral rehabilitation with conventionalof the insertion of new complete dentures (CD) in the oral health-related quality of life…
- Trial name
- NCT03687047
- Testing
- New complete dentures
- Where
- Brazil
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Health-related Quality of Life, Third Molar
"Impact of the Third Molars in Oral Health-related Quality of Life"
The aim of this study is to evaluate the impact of the third molars in oral health-related quality of life, before and after surgical removal using a validated and frequently used in international investigations instrument…
- Trial name
- NCT05044481
- Testing
- third molar surgical removal
- Where
- Chile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hospital Carlos Van Buren
Oral Habits, Oro-Facial Dysfunction
Oral Habits Effect on Orofacial Dysfunction and Oral Health Related Quality of Life.
The aim of the present study is to determine the effect of oral habits on orofacial dysfunction and oral health related quality of life among a group of Egyptian children.
- Trial name
- OHRQoL (NCT04575792)
- Testing
- Practicing oral habits
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin Hypersensitivity, Quality of Life
Validation of a French Version of the DHEQ
Dentin hypersensitivity (DH) results in brief, sharp pain in response to a stimulus. It often seems to be underdiagnosed but also undertreated due to the lack of consensus on the topic.
- Trial name
- DHEQ-VALID (NCT06466200)
- Testing
- Schiff Test, GOHAI questionnaire, OHIP questionnaire
- Where
- 3 sites in France
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Anorexia, Cachexia
Megestrol to Limit Weight Loss and Improve Quality of Life in Treating Patients With Head and Neck Cancer
RATIONALE: Megestrol helps improve appetite. It is not yet known if megestrol is effective in limiting weight loss caused by cancer.
- Conditions
- Anorexia, Cachexia, Head and Neck Cancer, Quality of Life
- Trial name
- NCT00006799
- Testing
- megestrol acetate, quality-of-life assessment
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Wake Forest University Health Sciences
Inflammatory Bowel Diseases, Periodontitis
Oral Health-related Quality of Life (OHRQoL) in Patients With Inflammatory Bowel Disease (IBD)
IBD patients have a higher risk of oral diseases that affect the oral mucosa, the teeth and the tooth supporting tissues. These conditions are often associated with pain, bleeding and impaired masticatory function which may have…
- Conditions
- Inflammatory Bowel Diseases, Periodontitis, Dental Caries, Tooth Loss
- Trial name
- OQal-MICI (NCT05096897)
- Testing
- Self-administrated questionnaires
- Where
- France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Lille