Clinical trials: Oral Malodor
Halitosis
Effect of an Investigational Lozenge (Biofresh® 4plus) Versus Placebo Control on Oral Malodor (Intra-Oral Halitosis)
This study is designed to evaluate the effect of an investigational lozenge with the enzyme polyphenol oxidase and green coffee extract in reducing and controlling intra-oral halitosis following immediate use and daily use of the…
- Trial name
- NCT05413382
- Testing
- Biofresh® 4plus
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Oral Malodor
Controlling Oral Malodor by ClōSYS Oral Rinse
The purpose of this Study is to assess the efficacy of two ClōSYS Oral Rinse products in human subjects in controlling oral malodor in partial fulfillment of the requirements for recognition by the American Dental Association's…
- Trial name
- NCT03160573
- Testing
- ClōSYS® Unflavored Rinse, ClōSYS® Flavored Rinse
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Rowpar Pharmaceuticals, Inc.
Oral Malodor
Clinical Investigation of Oral Malodor for Max Fresh Toothpaste Containing Zinc Citrate Versus a Commercially Available Regular Fluoride Toothpaste
The objective of this three-week clinical research study is to evaluate oral malodor for a toothpaste containing zinc citrate as compared to a commercially available regular fluoride toothpaste using the organoleptic method.
- Trial name
- NCT07398378
- Testing
- Max Fresh Toothpaste, Colgate Cavity Protection Toothpaste
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Oral Malodor
A Study to Evaluate Oral Malodor and Other Outcomes Following The Use of Two-Step Toothpaste Oral Hygiene
This study will assess changes in oral malodor and other factors in response to using a two-step toothpaste oral hygiene relative to a sensitivity whitening toothpaste.
- Trial name
- NCT02613130
- Testing
- Stannous fluoride toothpaste, Potassium nitrate toothpaste
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Oral Malodor
Clinical Study on Malodor
This 3-week clinical study was designed to investigate the clinical efficacy on oral malodor of a 0.454% stannous fluoride toothpaste with nitrate and pyrophosphate (referred to as SNAP) compared to Colgate Cavity Protection…
- Trial name
- NCT06300905
- Testing
- test product, Control product
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Periodontal Diseases, Gingivitis
Randomized Trial of a Gum Health Formulation
The purpose of this study is to evaluate the safety and efficacy of a newly formulated foaming gel product on gingivitis and/or moderate periodontitis when used with or without the GLO Science accelerating device (GLO Device)…
- Conditions
- Periodontal Diseases, Gingivitis, Periodontitis, Halitosis
- Trial name
- NCT03196648
- Testing
- Gingival health formulation in an accelerating device, Gingival health formulation on a toothbrush, OTC fluoride toothpaste
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Glo Science, Inc.
Oral Malodor
Controlling Oral Malodor by ClōSYS® Oral Rinse
The purpose of this Study is to assess the efficacy of two ClōSYS Oral Rinse products in human subjects in controlling oral malodor in partial fulfillment of the requirements for American Dental Association's (ADA) requirement…
- Trial name
- NCT03160560
- Testing
- ClōSYS® Unflavored Rinse, ClōSYS® Flavored Rinse
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rowpar Pharmaceuticals, Inc.
Oral Malodor
Clinical Study of the Effect of Two Experimental Lozenges on Oral Malodor After Single Use
The goal of this clinical trial is to compare the control of oral malodor between an investigational lozenge with the enzyme polyphenol oxidase plus green coffee extract or an investigational lozenge with color and flavor along…
- Trial name
- NCT05950529
- Testing
- Experimental lozenge with the enzyme Polyphenol oxidase and green coffee extract, Experimental lozenge with the enzyme Polyphenol oxidase, green coffee extract and flavor, No product
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Oral Bacteria, Halitosis
Effect of a Probiotic Water on Oral Health in Adults
The purpose of this study is to evaluate the effects of consuming a probiotic on salivary, plaque, and tongue bacteria, as well as oral malodor (bad breath).
- Trial name
- NCT04473404
- Testing
- Streptococcus salivarius DB-B5 - 2 billion CFU/day, Streptococcus salivarius DB-B5 - 10 billion CFU/day
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dose Biosystems Inc.
Oral Malodor
Four-Week Oral Malodor and Clinical Safety for a Concentrated Cosmetic Mouthwash
The objective of this study is to evaluate the safety of the concentrated mouthwash prototypes, and to evaluate the efficacy of the concentrated mouthwash prototypes in the control of oral malodor compared to a comparator…
- Trial name
- NCT06479096
- Testing
- Brush / Espresso Mild Prototype, Brush / Espresso Intense Prototype, Brush / Fresh Breath Oral Rinse
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Oral Malodor
A Clinical Study Conducted in the Bangkok, Thailand Area, to Investigate the Clinical Efficacy of a New Toothpaste
To investigate the clinical efficacy of a new toothpaste containing 0.454% stannous fluoride as compared to a regular fluoride toothpaste containing 0.76% sodium monofluorophosphate on oral malodor reduction via organoleptic…
- Trial name
- NCT07223073
- Testing
- 0.454% stannous fluoride, 0.76% sodium monofluorophosphate
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Oral Malodor (Halitosis)
Evaluation of a Stannous Fluoride Dentifrice for Control of Oral Malodor
This single-center, randomized, double-blind, two-treatment crossover clinical study evaluated the safety and efficacy of a stannous fluoride-containing dentifrice compared with a sodium fluoride control dentifrice for the…
- Trial name
- NCT07425509
- Testing
- Sodium Fluoride Dentifrice, Stannous Fluoride Toothpaste (SnF)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.