Clinical trials: Oral Potentially Malignant Lesions
Oral Cancer, Oral Cavity Cancer
Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions
The primary goal of this study is to see if photodynamic therapy (PDT) is effective for treatment of lesions in the oral cavity which have high risk of becoming oral cancer.
- Conditions
- Oral Cancer, Oral Cavity Cancer, Oral Leukoplakia, Oral Lichen Planus
- Trial name
- NCT06876038
- Testing
- 5-Amino Levulinic Acid
- Where
- 2 sites in India
- Volunteers
- 65 people
- Sponsor
- University of Massachusetts, Boston
Oral Neoplasm
Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment
The purpose of this observational study is to evaluate the utility of the S100A7 immunohistochemistry signature-based assessment - STRATICYTE - in determining the risk of progression to cancer of clinically suspicious oral…
- Trial name
- NCT04622462
- Testing
- Standard of Care Histopathology, STRATICYTE Assessment
- Where
- 3 sites in Canada
- Volunteers
- 500 people
- Sponsor
- Proteocyte Diagnostics Inc.
Oral Potentially Malignant Disorders, Oral Cavity Squamous Cell Carcinoma
Artificial Intelligence for the Diagnosis of Oral Lesions
Squamous cell carcinomas of the upper aerodigestive tract are among the most common cancers worldwide, with the oral cavity being the most frequent site.
- Trial name
- AID-OraL (NCT07529769)
- Volunteers
- 5,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prescription Drug Problems
Alternative Therapies Prescribed by Pharmacists and Herbalists
The cross-sectional study will recruit herbalists and pharmacists at their workplaces (herbal shops and pharmacies); where they will be asked their advice about a patient suffering from a potentially malignant condition.
- Trial name
- NCT06869395
- Testing
- Questionnaire
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Potentially Malignant Lesions
Cathelicidin LL-37 Relation to Potentially Malignant Lesions
LL-37 appears to have a potential role in potentially malignant lesions (OLP \& leukoplakia). The remarkable diagnostic accuracy of salivary LL-37 in differentiating potentially malignant lesion and healthy control could confirm…
- Trial name
- NCT06219330
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University