Clinical trials: Orientation, open to volunteers
Pregnancy, Fetal Presentation
Clinical Validation of an Artificial Intelligence System for De-termining Fetal Lie and Position in 3rd Trimester
This prospective clinical validation study aims to evaluate the diagnostic performance of an artificial intelligence (AI)-based navigational support system for determining fetal lie and presentation during third-trimester…
- Conditions
- Pregnancy, Fetal Presentation, Breech Fetal Presentation, Cephalic Fetal Presentation
- Trial name
- NCT07754071
- Where
- 3 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Post-Stroke Fatigue
Graded Activity Training and Task- Oriented Training on Post-Stroke Fatigue
The aim of this randomized controlled trial is to determine the effects of Graded Activity Training and Task Oriented Training on Fatigue in Post-Stroke Patients.
- Trial name
- NCT06846177
- Testing
- Graded Activity Training, Task-Oriented Training
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Virtual Reality
The Use of Immersive 360-degree Video in Improving Spatial Orientation
As medical students rotate through different hospital sites as part of their studies, the students are frequently exposed to new and unfamiliar environments.
- Trial name
- IMProVe (NCT05894005)
- Testing
- Immersive Virtual Reality (IVR), Traditional 2-D Video
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Sunnybrook Health Sciences Centre
Implementation Strategies
Demographic Data Collection in Healthcare
Collecting and using sexual orientation and gender identity (SOGI) data are the keys to systematically assessing and addressing the health and healthcare needs of sexual- and gender-diverse (SGD) people across all domains of…
- Trial name
- NCT07904078
- Testing
- Training, Implementation Strategy 1, Implementation Strategy 2
- Where
- United States
- Volunteers
- 1,320 people
- Sponsor
- Pacific Institute for Research and Evaluation
Cerebral Palsy (CP), Functional Mobility
Effects of Task Oriented Circuit Training on Functional Mobility and Activity Participation in Cerebral Palsy
cerebral palsy hemiplegia often experiences motor problems that primarily affect one side of their body. Children with hemiplegia have difficulties in functional activities.
- Trial name
- NCT07275528
- Testing
- Experimental, CONVENTIONAL PHYSICAL THERAPY
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Foundation University Islamabad
Nutrition, Healthy, Knowledge, Attitudes, Practice
Pilot Study of Capacity-oriented Intervention to Promote Food Security and Diet Quality Among Hispanics/Latinos
Despite a large proportion exhibiting cardiovascular disease risk factors and experiencing food insecurity, U.S. Hispanics/Latinos demonstrate low cardiovascular mortality, which may indicate existing capital (e.g., assets)…
- Conditions
- Nutrition, Healthy, Knowledge, Attitudes, Practice, Self Efficacy
- Trial name
- NCT05623202
- Testing
- Multi-level behavior-change intervention to strengthen food- and diet-related capital to promote food security and diet quality among low-income Hispanic/Latino adults
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Stroke
Standard vs Dual-Task Hand-Arm Bimanual Training in Post-Stroke Patients
This study aims to compare the effects of standard and dual-task-oriented hand-arm bimanual intensive training on cognitive performance, upper limb function, and coordination in post-stroke patients.
- Trial name
- NCT07578792
- Testing
- Standard HABIT, Dual-Task-Oriented HABIT
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Stroke, Stroke Rehabilitation
Volunteer Facilitated Discharge Assistance and Supports at Home (DASH) for People With Stroke
The goal of this clinical trial is to learn if a home visit by a trained volunteer can improve stroke recovery after a stroke survivor is discharged home from the hospital. The main questions it aims to answer are: 1.
- Conditions
- Stroke, Stroke Rehabilitation, Transitional Care
- Trial name
- DASH (NCT07590076)
- Testing
- Discharge Assistance and Supports at Home (DASH)
- Where
- 6 sites in Canada
- Volunteers
- 840 people
- Sponsor
- Bruyère Health Research Institute.
Hypertension
Household Salt Substitution for Hypertension Prevention and Control: The HOME-Salt Trial
Hypertension is a major risk factor for cardiovascular disease. Excess sodium intake and insufficient potassium intake contribute to elevated blood pressure, while replacing regular salt with a potassium-enriched salt substitute…
- Trial name
- HOME-Salt (NCT07840742)
- Testing
- Low-Sodium Salt Substitute, Regular Salt
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Shihezi University
Mental Health, Psychiatric Disorders
French Validation of the Recovery Assessment Scale (RAS-FR)
The VAL-RAS-FR study aims to cross-culturally adapt, validate, and develop derived versions of the Recovery Assessment Scale (RAS), an internationally used self-report measure of subjective recovery in mental health.
- Trial name
- VAL-RAS-FR (NCT07667686)
- Testing
- Self-report questionnaires
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Etablissement Public de Santé Mentale de Metz-Jury
Breast Cancer Survivor
Enhanced Pain Coping in Cancer (EPIC): A Study of Managing Treatment-Related Joint Pain in Breast Cancer Survivors
The researchers are doing this study to compare two different types of group therapy and find out whether they are effective approaches for helping breast cancer survivors manage joint pain caused by aromatase inhibitors (AI).
- Trial name
- NCT06728579
- Testing
- Mindfulness Oriented Recovery Enhancement (MORE), Questionnaires, Supportive Psychotherapy (SG)
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Schizophrenia, Bipolar Disorder
Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness
Many individuals with serious mental illness have difficulty accurately interpreting interpersonal cues and effectively engaging in social exchanges.
- Conditions
- Schizophrenia, Bipolar Disorder, Depressive Disorder, Major, Stress Disorder, Post-Traumatic
- Trial name
- NCT05491538
- Testing
- Social Cognition and Interaction Training-Work Edition (SCIT-WE)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Chronic Pain
Brief Mindfulness-Oriented Recovery Enhancement vs Brief Cognitive-Behavioral Therapy for Chronic Pain
This randomized controlled trial aims to test both English and Spanish versions of two, benign behavioral interventions for adults with chronic pain -- 1) Brief Mindfulness-Oriented Recovery Enhancement (B-MORE), and 2) Brief…
- Trial name
- B-MORE v B-CBT (NCT07207174)
- Testing
- Brief Mindfulness Oriented Recovery Enhancement, Brief Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Florida State University
Incentive Spirometer, Diaphragmatic Breathing
Effect of Breathing Training on Symptoms of Gastroesophageal Reflux Disease
The goal of this clinical trial is to evaluate whether two types of breathing training can improve symptoms of gastroesophageal reflux disease (GERD) in adults.
- Conditions
- Incentive Spirometer, Diaphragmatic Breathing, Gastroesophageal Reflux Disease (GERD), Breath Exercise
- Trial name
- NCT07179250
- Testing
- Volume-Oriented Incentive Spirometer, Diaphragmatic Breathing Exercise (DBE), Usual Care and Education
- Volunteers
- 51 people
- Sponsor
- Changhua Christian Hospital
Thyroid Cancer, Thyroid Diseases
Renovated Prediction Model for Difficult Transoral and Submental Endoscopic Thyroidectomy
The investigators have previously proposed a prediction model for difficult transoral and submental thyroidectomy through a retrospective study.
- Conditions
- Thyroid Cancer, Thyroid Diseases, Thyroid Nodule
- Trial name
- NCT06738888
- Testing
- Modified Strap-Muscle Dissection Technique
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai 6th People's Hospital
Anxiety Disorders, Depressive Disorder
Islamic-Oriented vs. Standard Ericksonian Hypnotherapy for Anxiety and Depression
This randomized controlled trial (RCT) aims to compare the effectiveness of Islamic-Oriented Ericksonian Hypnotherapy (IEH) and Standard Ericksonian Hypnotherapy (SEH) in reducing symptoms of anxiety and depression.
- Trial name
- IEH-RTC (NCT06844058)
- Testing
- Islamic-Oriented Ericksonian Hypnotherapy (IEH), Standard Ericksonian Hypnotherapy (SEH)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Postoperative Hypoalbuminemia, Postoperative Complications
Effect of Goal-Oriented Albumin Infusion on Postoperative Complication Management in Gastric Cancer Surgery
This study aims to evaluate the impact of goal-oriented albumin infusion on short-term postoperative outcomes in gastric cancer patients. It is a single-center, prospective, non-randomized controlled study.
- Conditions
- Postoperative Hypoalbuminemia, Postoperative Complications, Gastric Cancer
- Trial name
- GOAI (NCT07119463)
- Testing
- Human Serum Albumin Infusion for LAT Group, Human Serum Albumin Infusion for HAT Group
- Where
- China
- Volunteers
- 112 people
- Sponsor
- The First Hospital of Jilin University
Contrast-Induced Acute Kidney Injury
ImproviNg rEnal Outcomes Following Coronary angiograPhy and/or percuTaneoUs coroNary intErventions
The NEPTUNE triple-blind, active-placebo, adaptive, pragmatic, randomized trial aims to evaluate the effectiveness of a new intra-venous hydration strategy guided by left ventricular end-diastolic pressure (LVEDP), amount of…
- Trial name
- NEPTUNE (NCT04936607)
- Testing
- Personalized hydration strategy, Standard of care
- Where
- Canada
- Volunteers
- 1,158 people
- Sponsor
- Montreal Heart Institute
Flexor Tendon Injury, Splints
Evaluation of Eight-Strand Flexor Tendon Repair Without Splinting
This prospective cohort study evaluates functional outcomes of primary eight-strand flexor tendon repair in zone II without postoperative splinting in 40 adults (≥18 years) at Assiut University Hospitals.
- Conditions
- Flexor Tendon Injury, Splints, Flexor Tendon Repair, Flexor Tendon
- Trial name
- NCT07382193
- Volunteers
- 40 people
- Sponsor
- Assiut University
Amyotrophic Lateral Sclerosis
Spinal Cord Associative Plasticity for ALS
Veterans are at higher risk than non-Veterans of falling ill with amyotrophic lateral sclerosis (ALS). The investigators have shown that synchronized stimulation over the brain and cervical spinal cord can temporarily strengthen…
- Trial name
- NCT06172621
- Testing
- Spinal Cord Associative Plasticity (SCAP), Upper extremity task-oriented exercise
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- VA Office of Research and Development