Clinical trials: Orthodontic
Orthodontic Tooth Movement
OrthoPulse Gen 2 Initial Device Evaluation and Assessment of Clinical Effectiveness (CA)
This is a prospective, interventional, non-randomized, control, split-mouth, open-label, single centre, private practice study aimed to evaluate the effect of tooth movement during orthodontic treatment using a removeable…
- Trial name
- NCT04386278
- Testing
- Intervention 1, Intervention 2, Intervention 3
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Dental Plaque
Clinical Evaluation of the NeoPill Device for Reduction of Oral Bacterial Load in Patients With Fixed Orthodontic Appliances
This study evaluates the effectiveness of the NeoPill oral hygiene device in reducing oral bacterial load in adults wearing fixed orthodontic appliances.
- Trial name
- NCT07355400
- Testing
- NeoPill Oral Hygiene Device
- Where
- Cyprus
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Neofunction d.o.o.
Malocclusion
The Effects of Extraoral Photobiomodulation on the Rate of Orthodontic Alignment
The aim of this study is to determine if extraoral OrthoPulse®, which emits extraoral LED (Light Emitting Diode) photobiomodulation (PBM), reduces the time it takes to complete orthodontic alignment.
- Trial name
- NCT02267824
- Testing
- Extraoral OrthoPulse® PBM, Fixed Orthodontic Appliance Treatment
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 101 people
- Sponsor
- Biolux Research Holdings, Inc.
Orthodontic, Pain
Impact of Photobiomodulation on Pain Associated With Orthodontic Treatment
Orthodontic treatment can cause pain. Research studies have shown that light therapy can help reduce pain that is caused by orthodontic treatment.
- Trial name
- NCT06289595
- Testing
- PBM Ortho device
- Where
- 7 sites in Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- PBM Healing International Limited
Malocclusion, Orthodontic Treatment
Impact of Photobiomodulation on Pain During Orthodontic Treatment.
The objective of this study is to determine to effect of PBM Ortho, a photobiomodulation device, in adult patients undergoing clear aligners orthodontic treatment.
- Trial name
- NCT05361616
- Testing
- PBM Ortho
- Where
- 2 sites in Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- PBM Healing International Limited
Malocclusion
The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances
The aim of this study is to determine efficacy of OrthoPulse photobiomodulation on the rate of tooth movement during alignment for Subjects receiving fixed appliance orthodontic treatment.
- Trial name
- NCT03202355
- Testing
- Fixed Appliance Orthodontic Treatment, OrthoPulse™
- Where
- 3 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion
EXD-959 Orthodontic Brackets and EXD-961 Related Instruments Trial
The purpose of this study is to assess the performance of the EXD-959 self-ligating ceramic bracket system using EXD 961 instruments in the treatment of orthodontic malocclusion.
- Trial name
- NCT03606551
- Testing
- EXD-959 Bracket System
- Where
- 5 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- 3M
Orthodontic Pain
A Study of Acetaminophen/Naproxen Sodium Fixed Combination Tablets in Adolescents 12 to <17 Years of Age With Pain
The purpose of this study is to investigate the population pharmacokinetics of acetaminophen and naproxen from a novel acetaminophen /naproxen sodium fixed combination tablet in adolescents 12 to less than (<) 17 years of age…
- Trial name
- NCT05844995
- Testing
- Acetaminophen/Naproxen Sodium
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Malocclusion
The Effect of OrthoPulse™ Photobiomodulation on Tooth Movement and Treatment Time When Used With Invisalign Treatment
The aim of the study is to determine if, and to what degree photobiomodulation treatment with OrthoPulse has an effect on the rate of tooth movement during alignment for patients receiving Invisalign orthodontic aligner treatment.
- Trial name
- NCT02954133
- Testing
- Invisalign (7 day), Invisalign (5 day), OrthoPulse
- Where
- 4 sites in United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Teeth Straightening, Aligner Therapy
A Study to Compare Nighttime Aligners to Daytime Aligners
The purpose of this research study is to see if Nighttime Aligners (worn 10-12 hours per day or night) are effective and safe for tooth movement and if so, how they compare with the standard Daytime aligners (worn 20-22 hours per…
- Conditions
- Teeth Straightening, Aligner Therapy, Orthodontic Aligner
- Trial name
- NCT06539676
- Testing
- Nighttime Aligners, Daytime Aligners
- Where
- 12 sites in United States
- Volunteers
- 7 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Orthodontic Appliance Complication, Plaque, Dental
Regular Home Use of Dual-light Photodynamic Therapy on Oral Health in Adolescents Undergoing Fixed Orthodontic Treatment
This study is designed to determine the efficacy of the Lumoral method on oral health in adolescents undergoing fixed orthodontic treatment.
- Conditions
- Orthodontic Appliance Complication, Plaque, Dental, Gingival Inflammation
- Trial name
- NCT05825742
- Testing
- Lumoral Treatment, Standard oral health instructions
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Koite Health Oy
Dental Crowding, Malocclusion, Angle Class I
Treatment Outcome of Elastomeric and Nickel-Titanium Separators in Tooth Separation
Patients seeking fixed orthodontic treatment that requires band placement will be enrolled in this study. This trial aims to compare the efficiency of rectangular cross-section nickel-titanium separators with elastomeric…
- Trial name
- NCT07591454
- Testing
- Elastomeric separators, Nickel-Titanium separators
- Volunteers
- 30 people
- Sponsor
- 3D-Aligners