Clinical trials: Orthodontic Appliance
Malocclusion, Angle Class II
Comparison of Efficacy of Three Orthodontic Appliances
To investigate each treatment modality in its "optimal" environment to avoid operator experience bias. Therefore we propose to operate out of three "specialist centres" with specific units providing one modality alone Which of…
- Trial name
- NCT03450551
- Testing
- Twin Block, Herbst, Frog distalising appliance
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Taste Perception, Fixed Orthodontic Appliances
Taste Changes With Fixed Orthodontic Appliances
The aim of this research: 1. To analyze the possible influence of fixed orthodontic appliances on taste perception among patients undergoing conventional orthodontic treatment. 2.
- Trial name
- NCT06093256
- Testing
- Fixed orthodontic appliances
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Evaluations, Diagnostic Self, Antimicrobial
ZnO Nanoparticles Coated Orthodontic Molar Tube
Orthodontic treatment is an elective procedure to improve the patient's dentofacial appearance. The complex design of fixed appliances provides a platform that leads to increased plaque accumulation around orthodontic brackets.
- Conditions
- Evaluations, Diagnostic Self, Antimicrobial, Orthodontic Appliance Complication, Bacterial Overgrowth
- Trial name
- ZnONPs (NCT06089720)
- Testing
- Zinc oxide nanoparticle coated orthodontic molar tubes (experimental), orthodontic molar tubes (control)
- Where
- Iraq
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Crowding of Anterior Mandibular Teeth
Oral Health-Related Quality of Life Between Two Different Types of Orthodontic Appliances
Patients who have mild crowding from the Orthodontic Department at University of Damascus Dental School will be treated in this trial.
- Trial name
- NCT06401382
- Testing
- A modified aligner appliance with NiTi springs, Conventional fixed appliances
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Orthodontic Appliance Complication
Assessment of Pain When Removing Metallic Brackets for Orthodontic Patients Using Two Removal Methods
Patients at the Orthodontic Department of the University of Damascus Dental School will be examined, and subjects who meet the inclusion criteria will be included.
- Trial name
- NCT06873503
- Testing
- Bracket removal using a Weingart plier with the mouth open, Biting on a cotton roll during brakcet removal
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Effect of PowerScope Appliance in Treatment of Patients With Class 3 Malocclusion
Effect of Skeletally Anchored Reversed PowerScope Appliance in Orthodontic Treatment of Patients With Class III Malocclusion
the PowerScope appliance is found to be efficient for the treatment of class II malocclusion. Accordingly, it appears valuable to investigate the efficiency of skeletally anchored powerScope in the treatment of class III…
- Trial name
- NCT05475548
- Testing
- powerscope
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Class II Malocclusion
Effectiveness of Modified Functional Appliance With Expander
This clinical trial compares the effectiveness of a myofunctional appliance that uses a clear and modified twin block appliance with an expander made from 2mm biocompatible polyethylene terephthalate modified with Glycol…
- Trial name
- NCT06116500
- Testing
- Modified twin block appliance with expander, Conventional twin block appliance with expander
- Where
- Iraq
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Malocclusion, Orthodontic Appliance Complication
Microbiological and Epithelial Evaluation Related to the Use of Orthodontic Thermoplastic Device
Thermoplastic devices are used in orthodontic treatment and consists of a series of nearly invisible, removable aligners. However, every device used in the mouth can change the buccal flora and increase the number of bacterias.
- Trial name
- NCT02427763
- Testing
- hours of use (Essix), collect saliva, collect biofilm
- Where
- Brazil
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Universidade Positivo
Orthodontic Appliance Complication
Miniscrews Primary Stability
Orthodontic Miniscrew primary stability is essential for success and long term results. The aim of the present study is to evaluate Bone Properties and Torque insertion values and how they could be related to primary stability…
- Trial name
- NCT03696511
- Testing
- Orthodontic miniscrew insertion
- Where
- 3 sites in Italy, Spain
- Volunteers
- 30 people
- Sponsor
- University of Genova
Orthodontic Appliance Complication
Effect of Local Subperiosteal Zoledronic Acid Injection on the Survival of Orthodontic Miniscrews
Background: Orthodontic miniscrews are widely used as temporary anchorage devices; however, failure remains a clinical concern. Bisphosphonates may enhance bone stability, but evidence on their local application is limited.
- Trial name
- NCT07546058
- Testing
- Zoledronic Acid, Normal saline (0.9% sodium chloride)
- Where
- Syria
- Volunteers
- 68 people
- Sponsor
- Latakia University
Malocclusion
The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances
The aim of this study is to determine efficacy of OrthoPulse photobiomodulation on the rate of tooth movement during alignment for Subjects receiving fixed appliance orthodontic treatment.
- Trial name
- NCT03202355
- Testing
- Fixed Appliance Orthodontic Treatment, OrthoPulse™
- Where
- 3 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Orthodondic Appliances
A Survey on the Use of Removable Functional Appliances Among Patients Undergoing Treatment at the Orthodontic Unit of Nice University Hospital
The aim of the removable functional appliance is to restore functional balance (breathing, swallowing, chewing, etc.) and muscular balance (particularly of the facial muscles) in children.
- Trial name
- NCT07127341
- Testing
- Patient with removable functional appliance
- Where
- 2 sites in Belgium, France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Orthodontic Pain (D013850), Anxiety
Effect of Alpha Binaural Beat Music on Pain After Orthodontic Separator Placement
Orthodontic pain is one of the most frequently reported adverse experiences during fixed appliance therapy and is particularly pronounced during the initial stages of treatment.
- Trial name
- ABB-PainRCT (NCT07771920)
- Testing
- Alpha-Frequency Binaural Beat Music
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Aga Khan University
Gingivitis, Orthodontic Appliance Complication
Derma Pen as Treatment of Gingivitis Induced by Orthodontics
Although orthodontic therapy frequently improves tooth alignment and appearance, its problems with oral hygiene can make patients highly susceptible to gingivitis. After orthodontic treatment, gingivitis is a typical problem.
- Trial name
- NCT06567405
- Testing
- mechanical periodontal treatment, Derma pen with topical ascorbic Acid
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Safa Basiouny Alawy
Obstructive Sleep Apnea
Implant Supported Oral Appliance Treatment of OSA
Mandibular advancing oral appliances (OAm) are an effective and increasingly common treatment modality for the management of obstructive sleep apnea (OSA) in adults.
- Trial name
- BIMA (NCT03362671)
- Testing
- Implant Supported Mandibular Advancement Oral Appliance, Orthodontic Mini Implant
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of British Columbia
Orthodontic Appliance Complication
Smile Arc Assessment in Orthodontic Patients Following Smile Arc Protection VS MBT Placement Guide Bonding Strategies
The study will be performed on human subjects undergoing orthodontic treatment to correct mild crowding with both techniques enhancing the final smile characteristics of the patients.
- Trial name
- NCT05277506
- Testing
- 18 inch slot MBT orthodontic brackets bonded using smile arc protection bonding strategy, 18 inch slot MBT orthodontic brackets boned using MBT placement guide
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Occlusal Trauma, Orthodontic Appliance Complication
Importance of Neurogenic Inflammation in the Angiogenic Response of the Dental Pulp as a Defensive Response
This study measures SP, CGRP and VEGF expression in human dental pulp under occlusal trauma induced by occlusal interferences under moderate orthodontic forces or under a combination of occlusal trauma and moderate orthodontic…
- Trial name
- NCT03804034
- Testing
- Block of resin, Buccal tube, Bracket and 0.0017 × 0.025 in titanium molybdenum alloy wire
- Where
- Colombia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institucion Universitaria Colegios de Colombia
Orthodontic Appliance Complication
Control of Pain From Braces With Patient Advice Sheets
To compare the analgesic property of acupressure with NSAIDs (Ibuprofen) in controlling pain following orthodontic treatment. This will be achieved by assessing the effectiveness of acupressure in controlling pain and discomfort…
- Trial name
- COPPAS (NCT03159520)
- Testing
- Advice sheet
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- University of Dundee
White Spot Lesion
White Spot Lesions Treatment in Orthodontic
The study aims to investigate the effectiveness of a new treatment for demineralized white spot lesions (WSLs) after fixed appliance therapy.
- Trial name
- WSL (NCT06051981)
- Testing
- 5% sodium fluoride, Intensive 5% sodium fluoride, Casein Phosphopeptide-Amorphous Calcium Phosphate
- Volunteers
- 88 people
- Sponsor
- Riyadh Elm University
Obstructive Sleep Apnea
Evaluation of a Mandibular Advancement Device in the Treatment of Obstructive Sleep Apnea Syndrome
The purpose of this study is to determine if the mandibular advancement by Herbst device is effective in the treatment of moderate obstructive sleep apnea patients.
- Trial name
- NCT00213434
- Testing
- Herbst oral appliance
- Where
- France
- Sponsor
- University Hospital, Rouen