Clinical trials: Orthodontic Appliances
Orthodontics
Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) - Based Planning and Creation of Orthodontic Appliances
In orthodontics, conventional fixed appliances, usually consisting of prefabricated components, require step-by-step adjustment in order to move teeth in the planned direction.
- Trial name
- NCT00871026
- Testing
- orthodontic treatment with customized archwires, orthodontic treatment with prefabricated archwires
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Charite University, Berlin, Germany
Gingivitis, Orthodontic Appliance Complication
Derma Pen as Treatment of Gingivitis Induced by Orthodontics
Although orthodontic therapy frequently improves tooth alignment and appearance, its problems with oral hygiene can make patients highly susceptible to gingivitis. After orthodontic treatment, gingivitis is a typical problem.
- Trial name
- NCT06567405
- Testing
- mechanical periodontal treatment, Derma pen with topical ascorbic Acid
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Safa Basiouny Alawy
Gingivitis, Periodontal Inflammation
Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment in Adult Patients
Orthodontic treatment with fixed appliances can be necessary to correct malocclusions in adolescence or adulthood. It its known that orthodontic treatment induces aseptic pseudo-inflammatory reactions.
- Conditions
- Gingivitis, Periodontal Inflammation, Orthodontic Appliance Complication
- Trial name
- NCT04606186
- Testing
- Lactobacillus reuteri Prodentis®-lozenges (DSM 17938, ATCC PTA 5289)
- Where
- Germany
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg
Oral Hygiene
Effect of Dental Waterjet on Oral Hygiene for Patients With Braces
The aim of this study is to assess the efficacy of dental water jet in plaque removal and gingival health during orthodontic treatment with fixed appliances.
- Trial name
- NCT03119441
- Testing
- Dental Water Jet, Dental Floss
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Orthodontic Tooth Movement
Acceleration of Tooth Movement Using PRP and Photobiomodulation With Clear Aligners
This study compares the effectiveness of two adjunct therapies- photobiomodulation (low-level laser therapy) (PBM) and localized platelet-rich plasma (PRP) injections in accelerating orthodontic tooth movement.
- Trial name
- NCT07795073
- Testing
- Platelet Rich Plasma (PRP) injection, photobiomodulation (PBM) Therapy, clear aligner(12-hour wear protocol)
- Where
- Yemen
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Orthodontic Appliance Complication, Halitosis
Cotinus Coggygria Mouthwash and Halitosis and Oral Hygiene in Orthodontic Patients
The aim of this trial was to investigate the effect of Cotinus Coggygria mouthwash on halitosis using as proxy the levels of the Volatile Sulfur Compounds (VSCs), and the effect on plaque and gingival indices in adolescents…
- Trial name
- NCT07254819
- Testing
- Cotinus Coggygria mouthwash
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Athens
Orthodontic Appliance Complication, Gingival Overgrowth
Scalpel Versus Laser Gingivectomy in Orthodontic Patients in the Management of Periodontal Health
Patients undergoing orthodontic treatment with fixed appliances usually develop gingival enlargement (GE). Its development is usually attribute to chronic inflammation, and may cause both esthetic and functional problems for the…
- Trial name
- NCT03514316
- Testing
- Scalpel Gingivectomy, Laser Gingivectomy, Nonsurgical periodontal treatment
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Rome Tor Vergata
Dental Crowding, Alveolar Bone Loss
Bone Level Changes Using Clear Aligners Compared to Fixed Appliances in Non-Extraction Treatment of Adults
This study compares two common ways of straightening teeth in adults who have mild-to-moderate crowding of the lower front teeth and do not need any teeth removed: clear aligners and traditional fixed braces.
- Conditions
- Dental Crowding, Alveolar Bone Loss, Malocclusion
- Trial name
- NCT07716007
- Testing
- Fixed orthodontic appliance, Clear aligners
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Orthodontic Appliances, Removable, Orthodontic Appliances, Fixed
Microbiome and Immunogenity of Saliva During Orthodontic Therapy
There are two essential ways of treatment in the field of orthodontics. The fixed appliance treatment with self-ligating or conventional brackets and treatment with aligners.
- Conditions
- Orthodontic Appliances, Removable, Orthodontic Appliances, Fixed, Oral Microbiome, Cell Culture
- Trial name
- NCT04139538
- Testing
- orthodontic treatment
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Orthodontic Treatment, Fixed Appliances
Effectiveness of Insignia ™ Versus Standard Orthodontic Treatment With Damon Q Brackets
The hypotheses tested in this study are: There is a statistical significant difference, in treatment duration and result of treatment in cases treated using traditional Damon Q brackets or using Insignia.
- Conditions
- Orthodontic Treatment, Fixed Appliances, Insignia, DamonQ Brackets
- Trial name
- NCT01268852
- Testing
- Damon self ligating orthodontic bracket, Insignia self ligating orthodontic bracket
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- Radboud University Medical Center
Crowding, Tooth
Evaluating the Influence of Showing Patients Their Predicted Teeth Alignment on Their Expectations and Satisfaction
Patients who have moderate crowding will be treated in this study. The efficacy of showing the predicted alignment of patient's teeth at the end of orthodontic treatment previously to treatment on their expectations from…
- Trial name
- NCT05010616
- Testing
- Fixed orthodontic appliances
- Where
- Syria
- Volunteers
- 25 people
- Sponsor
- Damascus University
Maxillary Expansion, Forensic Dentistry
Evaluation of Palatal Rugae-Based Identification After Maxillary Expansion Using Local Morphological Patch Analysis
This study investigates the reliability of palatal rugae-based identification following maxillary expansion procedures, including Miniscrew-Assisted Rapid Palatal Expansion (MARPE) and Surgically Assisted Rapid Maxillary…
- Conditions
- Maxillary Expansion, Forensic Dentistry, Intraoral Scanner, Orthodontic Appliance
- Trial name
- NCT07667933
- Testing
- SARME, MARPE, Untreated Control
- Where
- Hungary
- Volunteers
- 45 people
- Sponsor
- Semmelweis University
Caries
Effect of Enzyme-containing Mouth Rinse on Dental Biofilm in Patients With Fixed Orthodontic Appliances
Caries is a biofilm-mediated global public health problem causing health, social and economic consequences for individuals, communities and countries.
- Trial name
- NCT05033015
- Testing
- Mouth rinse
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Malmö University
Halitosis, Periodontal Health
Effects of Green Tea Mouthwash on Halitosis, Periodontal Health, and Stress in Orthodontic Patients
This randomized, double-blind, four-arm clinical trial evaluates the effects of green tea mouthwash on halitosis, periodontal health, salivary stress biomarkers, and oxidative stress in patients undergoing fixed orthodontic…
- Conditions
- Halitosis, Periodontal Health, Orthodontic Treatment
- Trial name
- NCT07829224
- Testing
- Green Tea Mouthwash A, Green Tea Mouthwash B, Fluoride Mouthwash
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Universiti Sains Malaysia
Analgesia, Orthodontic Appliance Complication
Comparison of Different Methods of Controlling Pain During Debonding of Orthodontic Brackets
Purpose of this study was to evaluate different methods of controlling pain during debonding
- Trial name
- NCT05104190
- Testing
- Stabilization of teeth during debonding using fingure pressure and elastic wafer
- Where
- Pakistan
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Orthodontic Appliance Complication
Control of Pain From Braces With Patient Advice Sheets
To compare the analgesic property of acupressure with NSAIDs (Ibuprofen) in controlling pain following orthodontic treatment. This will be achieved by assessing the effectiveness of acupressure in controlling pain and discomfort…
- Trial name
- COPPAS (NCT03159520)
- Testing
- Advice sheet
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- University of Dundee
Halitosis, Orthodontic Appliance Complication
Chios Mastic Toothpaste and Halitosis and Oral Hygiene in Orthodontic Patients
The aim of this trial was to investigate the effect of mastic toothpaste on halitosis using as proxy the levels of the Volatile Sulfur Compounds (VSCs), and the effect on plaque and gingival indices in adolescents undergoing…
- Trial name
- NCT06766097
- Testing
- mastic toothpaste
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Athens
Root Resorption, Orthodontic Appliance Complication
Proteomics and Orthodontic Root Resorption
The majority of previous studies for early detection of Orthodontically Induced Inflammatory Root Resorption (OIIRR) were conducted to assess individual biomarkers which are representative of single biological pathway.
- Conditions
- Root Resorption, Orthodontic Appliance Complication, Orthodontic Pathological Resorption of External Root, Gingival Diseases
- Trial name
- NCT04291443
- Testing
- Heavy Force (225g), Light Force (25g)
- Where
- Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Baghdad