Clinical trials: Orthodontic Pain
Orthodontic Appliance Complication
Assessment of Coated Orthodontic Miniscrews With Chlorhexidine Hexametaphosphate Antimicrobial Nanoparticles
Aim To compare between orthodontic miniscrews coated and uncoated with CHX- HMP NP nanoparticles.
- Trial name
- NCT06124235
- Testing
- Coated Orthodontic Miniscrews with Chlorhexidine Hexametaphosphate Nanoparticles, Uncoated Miniscrew with Chlorhexidine Hexametaphosphate Nanoparticles
- Where
- Iraq
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Orthodontic Pain (D013850)
Efficacy of Different Regiments of 980 nm Low-Level Laser Therapy to Reduce Pain Caused by Orthodontic Separators: A Randomized, Double-Blind, Split-Mouth Placebo-Controlled Study
Thirty-one (n=31) participants from the Department of Orthodontics and Pediatric Dentistry, University of Szeged will be randomly assigned using a split-mouth design, to avoid inter-individual variability between participants…
- Trial name
- SZTEDENTlaser2 (NCT07456709)
- Testing
- Low Level Laser Therapy, No interventions
- Where
- Hungary
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Szeged University
Orthodontic Pain (D013850), Malocclusion
Comparison of Three Orthodontic Separators for Pain, Plaque, and Tooth Separation
Orthodontic separators are small devices placed between teeth before fitting braces to create space for bands. This procedure may cause pain, discomfort, and changes in oral hygiene, which can affect plaque buildup and daily…
- Conditions
- Orthodontic Pain (D013850), Malocclusion, Orthodontic Treatment
- Trial name
- SEP-ORTHO (NCT07532044)
- Testing
- Elastomeric Separator, Kesling Separator, Tie wire separator
- Where
- Pakistan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Islamabad Medical and Dental College
Orthodontic, Interproximal Enamel Reduction
Pain Associated With Interproximal Enamel Reduction in Orthodontics: a RCT
Prospective randomised crossover trial to assess if there is a difference in the level of pain experienced by orthodontic patients undergoing interpromixal enamel reduction at the lower incisor region using either a motor driven…
- Trial name
- IER (NCT02455700)
- Testing
- Interproximal Enamel Reduction
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Pain
Placebo Modulation of Orthodontic Pain
How placebo modulates orthodontic pain remains largely unknown. The present study aimed to investigate the placebo modulation of brain activity associated with orthodontic pain using fMRI.
- Trial name
- NCT03689517
- Testing
- orthodontic elastic separators
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Orthodontic Pain
A Study of Acetaminophen/Naproxen Sodium Fixed Combination Tablets in Adolescents 12 to <17 Years of Age With Pain
The purpose of this study is to investigate the population pharmacokinetics of acetaminophen and naproxen from a novel acetaminophen /naproxen sodium fixed combination tablet in adolescents 12 to less than (<) 17 years of age…
- Trial name
- NCT05844995
- Testing
- Acetaminophen/Naproxen Sodium
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Malocclusion, Deep Bite
Pain and Discomfort With Anterior Versus Posterior Builds-up
Orthodontic build-ups are made by composite/resin material bonded to the palatal or occlusal surfaces of teeth (usually molars or incisors).
- Trial name
- NCT04105127
- Testing
- orthodontic - Anterior resin builds-ups, orthodontic - Posterior resin builds-ups
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Genova
Malocclusion, Orthodontic Treatment
Impact of Photobiomodulation on Pain During Orthodontic Treatment.
The objective of this study is to determine to effect of PBM Ortho, a photobiomodulation device, in adult patients undergoing clear aligners orthodontic treatment.
- Trial name
- NCT05361616
- Testing
- PBM Ortho
- Where
- 2 sites in Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- PBM Healing International Limited
Acceleration of Tooth Movement
The Effect of Low-Level Laser Therapy on Accelerating Tooth Movement and Reducing Pain During Orthodontic Treatment
Orthodontic treatment is a common and effective approach to correcting dental malocclusions and improving oral function and aesthetics.
- Trial name
- LLLT (NCT07591948)
- Testing
- Low level laser therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Malocclusion
Laser Therapy on Controlling Pain During Orthondontic Treatment
To evaluate the effectiveness of pain reduction on a initial orthodontic treatment by using 810nm Diode laser compared to a placebo.
- Trial name
- NCT04628390
- Testing
- Laser
- Where
- Colombia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fundación Universitaria CIEO
Orthodentic Appliances, Orthodontic Pathological Resorption of External Root
Comparative Outcomes of Damon Ultima vs Pitts 21 Pro Bracket Systems
Title Comparative Evaluation of Treatment Outcomes between Damon Ultima and Pitts 21 Pro Bracket Systems; A Randomized Clinical Trial Abstract Background: The primary advantages of self-ligation brackets include faster archwire…
- Conditions
- Orthodentic Appliances, Orthodontic Pathological Resorption of External Root, Orthodontic Pain, Orthodontic Brackets
- Trial name
- NCT07318623
- Testing
- Treatment outcome of Damon ultima, Treatment outcome of pitt21 pro
- Where
- 2 sites in Iraq
- Volunteers
- 40 people
- Sponsor
- University of Baghdad
Orthodontic Pain
The Effect of Low-level Laser Therapy to Reduce Pain Caused by Orthodontic Separators: A Randomized, Double-blind Place-bo-controlled, Split-mouth Study
Thirty-three (n=33) participants from the Department of Orthodontics and Pediatric Dentistry, University of Szeged will be randomly assigned into two groups.
- Trial name
- SZTEDENT-laser (NCT06816537)
- Testing
- Low Level Laser Therapy, No Interventions
- Where
- Hungary
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Szeged University
Root Resorption, Pain
Side Effects of Different Treatment Methods
this study aimed to compare the effects of fixed orthodontic treatment and clear aligner therapy on root resorption, periodontal status, pain experience and chewing performance.
- Conditions
- Root Resorption, Pain, Chewing Function
- Trial name
- NCT06709287
- Testing
- clear aligners, orthodontic metal bracket
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Orthodontic Appliance Complication
Influence of Low Level Laser Therapy on the Rate of Orthodontic Tooth Movement and Associated Pain
This is a single blind randomized controlled trial with split mouth design including 45 patients with extractions of maxillary 1st bicuspids.
- Trial name
- NCT05120102
- Testing
- Diode laser
- Where
- Pakistan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Orthodontic Discomfort, Pain, Orofacial
Comparison of Patient-reported Pain After Initial Archwire Placement
Three different types of 'archwires' can be used in Orthodontic treatment, wire choice is decided by treating Orthodontist based on professional preference since research shows that all types are equally effective.
- Trial name
- Archwires (NCT03906422)
- Testing
- 3M Unitek 0.016 orthodontic archwire, Device: 0.016" Ormco 27oC NiTi orthodontic archwire, Device: 0.016" Ormco 35oC NiTi orthodontic archwire
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Orthodontic Pain (D013850)
Efficacy of Selective COX-2 Inhibitors in Relieving Orthodontic Pain
The purpose of this study is to compare the efficacy of selective COX-2 inhibitors{ etoricoxib vs celecoxib )in relieving orthodontic pain , after initial bonding and arch wire insertion.
- Trial name
- EOSCOX2 (NCT07559682)
- Testing
- Celecoxib, Etoricoxib (Treatment Group)
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Sharif Medical Research Center
Crowding, Tooth
The Effects of Ibuprofen and Laser on Orthodontic Pain
Early orthodontic pain is usually caused by the insertion of elastomeric separators to the mesial and distal of the tooth to be banded in order to create adequate space for proper placement.
- Trial name
- NCT04070001
- Testing
- 400 Mg Ibuprofen, laser application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yeşim KAYA
Orthodontic Appliance Complication
Assessment of Pain When Removing Metallic Brackets for Orthodontic Patients Using Two Removal Methods
Patients at the Orthodontic Department of the University of Damascus Dental School will be examined, and subjects who meet the inclusion criteria will be included.
- Trial name
- NCT06873503
- Testing
- Bracket removal using a Weingart plier with the mouth open, Biting on a cotton roll during brakcet removal
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Pain
A Split Mouth Study to Evaluate Transcutaneous Electrical Nerve Stimulation as an Effective Non-pharmacological Approach in Managing Pain During Initial Orthodontic Treatment - A Randomized Controlled Trial
Orthodontic treatment often causes pain during the initial alignment stage which can lead to discomfort, reduced compliance, and slower treatment progress.
- Trial name
- TENS (NCT07760337)
- Testing
- TENS
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Pain, Orofacial
Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain Management
The purpose of this study is to compare the effectiveness of a combined ibuprofen and acetaminophen regimen in controlling discomfort for 4 days after initial orthodontic appliance placement as compared to ibuprofen alone or a…
- Trial name
- NCT04059172
- Testing
- Ibuprofen 200 mg and acetaminphen 650 mg, Ibuprofen 200 mg
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver