Clinical trials: Orthodontic Pain, active
Orthodontics, Root Resorption
Effects of PBM on Fixed-appliance Orthodontic Patients
The aim of this study is to investigate the effects of photobiomodulation therapy (PBM) on the dental and periodontal health of patients undergoing fixed-appliance orthodontic treatment, including orthodontically induced root…
- Trial name
- NCT06199674
- Testing
- photobiomodulation therapy, orthodontic fixed-appliance
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Orthodontic Discomfort, Pain, Orofacial
Comparison of Patient-reported Pain After Initial Archwire Placement
Three different types of 'archwires' can be used in Orthodontic treatment, wire choice is decided by treating Orthodontist based on professional preference since research shows that all types are equally effective.
- Trial name
- Archwires (NCT03906422)
- Testing
- 3M Unitek 0.016 orthodontic archwire, Device: 0.016" Ormco 27oC NiTi orthodontic archwire, Device: 0.016" Ormco 35oC NiTi orthodontic archwire
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Orthodontic Pain (D013850), Malocclusion
Comparison of Three Orthodontic Separators for Pain, Plaque, and Tooth Separation
Orthodontic separators are small devices placed between teeth before fitting braces to create space for bands. This procedure may cause pain, discomfort, and changes in oral hygiene, which can affect plaque buildup and daily…
- Conditions
- Orthodontic Pain (D013850), Malocclusion, Orthodontic Treatment
- Trial name
- SEP-ORTHO (NCT07532044)
- Testing
- Elastomeric Separator, Kesling Separator, Tie wire separator
- Where
- Pakistan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Islamabad Medical and Dental College
We Are Not Studying a Disease or Condition, Pain Reduction
Effect of Diode Laser and 20% Benzocaine Anesthetic Gel on Pain Reduction Following Tooth Separation With Elastomeric Separators in Fixed Orthodontic Patients: A Randomized Trial in Karachi-Pakistan
The goal of this clinical trial is to learn if low level laser therapy works equivalent to benzocaine in reducing the pain caused by separators in fixed orthodontic treatment.
- Trial name
- NCT07558720
- Testing
- Laser, Benzocaine 20%
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Orthodontic Pain
Pain Control During Braces Removal Using Transcutaneous Electrical Nerve Stimulation and High-Frequency Vibration
This study aims to find the best method to reduce pain during braces removal. We are comparing transcutaneous electrical nerve stimulation (TENS), high-frequency vibration, and a control group with no additional intervention.
- Trial name
- NCT07293975
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), High-Frequency Vibration
- Where
- Iraq
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Pain, Orofacial
Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain Management
The purpose of this study is to compare the effectiveness of a combined ibuprofen and acetaminophen regimen in controlling discomfort for 4 days after initial orthodontic appliance placement as compared to ibuprofen alone or a…
- Trial name
- NCT04059172
- Testing
- Ibuprofen 200 mg and acetaminphen 650 mg, Ibuprofen 200 mg
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Orthodontic Appliance, Pain
The Effect of Intraoral Transcutaneous Electrical Nerve Stimulation in Orthodontics Pain
The goal of this clinical trial is to determine whether an intraoral Transcutaneous Electrical Nerve Stimulation (TENS) device can reduce pain during orthodontic alignment and leveling in adolescents and adults.
- Conditions
- Orthodontic Appliance, Pain, Transcutaneous Electric Nerve Stimulation, Orthodontic Appliance Complication
- Trial name
- NCT06573996
- Testing
- Active TENS Device
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of the Pacific
Malocclusion of Anterior Teeth
Effects of Laser Therapy and Vitamin D Pills on Braces Tooth Movement: A Random Controlled Study
This clinical trial aims to evaluate the efficacy of low-level laser therapy (LLLT) in conjunction with oral vitamin D3 supplementation in accelerating orthodontic tooth movement in adults with crowded mandibular anterior teeth…
- Trial name
- LLLT (NCT07286474)
- Testing
- Cholecalciferol (Vit D3), Low-Level Laser Therapy, Fixed Orthodontic Appliance
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Orthodontic Pain (D013850)
Efficacy of Selective COX-2 Inhibitors in Relieving Orthodontic Pain
The purpose of this study is to compare the efficacy of selective COX-2 inhibitors{ etoricoxib vs celecoxib )in relieving orthodontic pain , after initial bonding and arch wire insertion.
- Trial name
- EOSCOX2 (NCT07559682)
- Testing
- Celecoxib, Etoricoxib (Treatment Group)
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Sharif Medical Research Center
Orthodontic Pain
Comparison Between the Effectiveness of Low-Grade Laser Therapy vs. Conventional Analgesics for Pain Reduction During Orthodontic Treatment in Malay Female Population
All patients will be treated using the fixed appliance on the upper and lower arches. 0.014" Niti(Nickel-Titanium) archwire is used to ensure all patients will receive the same force. All participants will receive a pain diary.
- Trial name
- LLTvsANALG (NCT07747350)
- Testing
- Low-Level Laser Therapy (LLLT), Conventional Analgesic (Paracetamol)
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- ROA RAAD FADHEL
Orthodontic Brackets, Pain
Erbium-doped Yttrium Aluminum Garnet (Er:YAG) Laser vs Conventional Ceramic Bracket Debonding: A Split-Mouth Clinical Trial
This randomized split-mouth clinical trial evaluates enamel surface preservation, pulpal temperature variation, and patient-reported discomfort during ceramic orthodontic bracket removal using two Erbium-doped yttrium aluminum…
- Conditions
- Orthodontic Brackets, Pain, Temperature Change, Laser
- Trial name
- NCT07517601
- Testing
- Er:YAG Laser - Parameter 1, Er:YAG Laser - Parameter 2, Conventional Mechanical Debonding
- Where
- Lebanon
- Volunteers
- 10 people
- Sponsor
- Saint-Joseph University
Orthodontic Appliances
Orthodontic Pain Alleviation With Chewing Gum
The aim of this study is to determine whether chewing gum can alleviate orthodontic treatment discomfort and improve orthodontic treatment experience.
- Trial name
- NCT07210697
- Testing
- Xylitol Gum
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- West Virginia University
Orthodentic Appliances, Orthodontic Pathological Resorption of External Root
Comparative Outcomes of Damon Ultima vs Pitts 21 Pro Bracket Systems
Title Comparative Evaluation of Treatment Outcomes between Damon Ultima and Pitts 21 Pro Bracket Systems; A Randomized Clinical Trial Abstract Background: The primary advantages of self-ligation brackets include faster archwire…
- Conditions
- Orthodentic Appliances, Orthodontic Pathological Resorption of External Root, Orthodontic Pain, Orthodontic Brackets
- Trial name
- NCT07318623
- Testing
- Treatment outcome of Damon ultima, Treatment outcome of pitt21 pro
- Where
- 2 sites in Iraq
- Volunteers
- 40 people
- Sponsor
- University of Baghdad
Dental Crowding, Dental Occlusion, Traumatic
Exploration of the Utility of Dental-dedicated MRI for Dentistry
This description observational research is comparative in design, that is comparing existing standard clinical dental images, not obtained in this study, to test (i.e., ddMRI) images.
- Conditions
- Dental Crowding, Dental Occlusion, Traumatic, Endodontic Disease, Orthodontic Treatment
- Trial name
- NCT06948162
- Testing
- dental-dedicated MRI (ddMRI)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Malocclusion
Comparison of Acupressure, Ibuprofen, and Chewing Gum for the Management of Post-Archwire Orthodontic Pain
The goal of this clinical trial is to find out which method works best to reduce pain after braces are adjusted for the first time (when the first archwire is placed).
- Trial name
- NCT07638644
- Testing
- Acupressure, Ibuprofen 400 mg (if necessary), Chewing Gum
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Bahria University
Dental Crowding, Malocclusion, Angle Class I
Treatment Outcome of Elastomeric and Nickel-Titanium Separators in Tooth Separation
Patients seeking fixed orthodontic treatment that requires band placement will be enrolled in this study. This trial aims to compare the efficiency of rectangular cross-section nickel-titanium separators with elastomeric…
- Trial name
- NCT07591454
- Testing
- Elastomeric separators, Nickel-Titanium separators
- Volunteers
- 30 people
- Sponsor
- 3D-Aligners
Maxillary Constriction
Comparison of Laboratory-Fabricated and 3D-Printed Rapid Maxillary Expansion Appliances
The goal of this clinical trial is to determine whether two types of rapid maxillary expansion (RME) appliances produce different outcomes in children. RME is a treatment utilized to expand a narrow upper jaw.
- Trial name
- NCT07599202
- Testing
- Laboratory-fabricated rapid maxillary expansion appliance, 3D-printed rapid maxillary expansion appliance
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Baskent University
Malocclusions
Effects of Vitamin D in Patients Undergoing Fixed Orthodontic Mechanotherapy
The goal of this interventional research is to determine the impact of vitamin D intake on substances in saliva, pain, tooth movement, and the density of the bone around teeth in patients during orthodontic treatment.
- Trial name
- NCT07299552
- Testing
- Vitamin D (Calcitriol)
- Where
- Malaysia
- Volunteers
- 48 people
- Sponsor
- Hospital Universiti Sains Malaysia
Orthodontic Pain (D013850), Pain Management (D016146)
A Randomized Clinical Trial of the Effectiveness of Acupressure in Relieving Orthodontic Pain
Orthodontic treatment with fixed appliances often causes pain, which peaks within 24 hours after archwire placement and lasts for several days.
- Conditions
- Orthodontic Pain (D013850), Pain Management (D016146), Acupressure (D056351), Analgesics, Non-Narcotic (D000700)
- Trial name
- NCT06812936
- Testing
- Acetaminophen, Acupressure
- Where
- Iraq
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Orthodontic Pain (D013850), Anxiety
Effect of Alpha Binaural Beat Music on Pain After Orthodontic Separator Placement
Orthodontic pain is one of the most frequently reported adverse experiences during fixed appliance therapy and is particularly pronounced during the initial stages of treatment.
- Trial name
- ABB-PainRCT (NCT07771920)
- Testing
- Alpha-Frequency Binaural Beat Music
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Aga Khan University