Clinical trials: Orthodontic Treatment
Dental Malocclusion
Effect of Low Level Laser on Orthodontic Canine Retraction
The aim of this study was to determine whether orthodontically moved maxillary canines exposed to two different protocols and dosage of LLLT exhibited differences in amount and rate of orthodontic tooth movement.
- Trial name
- NCT04381442
- Testing
- Low Level Laser Therapy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion
Analysis of Patient Seeking Second Opinion Who Are Undergoing Full Mouth Orthodontic Treatment
Patient safety is a great concern for the whole society. Since the investigators have a leadership in the medical field in Taiwan, the investigators should be courageous to face the reality from the patients seeking second…
- Trial name
- NCT01538524
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Malocclusion, Angle Class I, Malocclusion; Displaced or Missing Teeth
Comparison Between Clear Aligners and Traditional Fixed Appliances in the Treatment of Four-premolar-extraction Cases
Patients who have severe crowding that require four premolars extraction will be treated in this study. The efficacy of the clear aligners and vestibular fixed appliances will be assessed.
- Conditions
- Malocclusion, Angle Class I, Malocclusion; Displaced or Missing Teeth, Crowding
- Trial name
- NCT03645356
- Testing
- Fixed Appliances, Clear Aligners
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Sleep Apnea Syndrome, Malocclusion
Pharyngeal Size in Patients With Obstructive Tonsils Under Orthodontic Treatment
Enlarged tonsils and malocclusion have relationship with sleep disturbance in children. The consequences of these features can include deviation of normal craniofacial growth such that this may result in a facial morphology more…
- Trial name
- NCT01164631
- Testing
- Bioajusta X Orthodontic treatment
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Orthodontic, Pain
Impact of Photobiomodulation on Pain Associated With Orthodontic Treatment
Orthodontic treatment can cause pain. Research studies have shown that light therapy can help reduce pain that is caused by orthodontic treatment.
- Trial name
- NCT06289595
- Testing
- PBM Ortho device
- Where
- 7 sites in Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- PBM Healing International Limited
Orthodontic Pain (D013850), Pain Management (D016146)
A Randomized Clinical Trial of the Effectiveness of Acupressure in Relieving Orthodontic Pain
Orthodontic treatment with fixed appliances often causes pain, which peaks within 24 hours after archwire placement and lasts for several days.
- Conditions
- Orthodontic Pain (D013850), Pain Management (D016146), Acupressure (D056351), Analgesics, Non-Narcotic (D000700)
- Trial name
- NCT06812936
- Testing
- Acetaminophen, Acupressure
- Where
- Iraq
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Fixed Orthodontic Retainer
Ultrasonographic Evaluation of Periodontal Effects of Fixed Retainers
This prospective clinical study aims to evaluate the effects of fixed lingual retainers placed after orthodontic treatment on periodontal soft and hard tissue parameters using ultrasonographic imaging.
- Trial name
- NCT07414264
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Selcuk University
Malocclusion Class I
Diode Laser Versus LED for Maxillary Canine Retraction in Orthodontic Patients
This study aims to compare the effects of diode laser and light-emitting diode (LED) photobiomodulation on maxillary canine retraction during fixed orthodontic treatment.
- Trial name
- NCT07810699
- Testing
- Diode Laser Photobiomodulation, LED Photobiomodulation
- Where
- Vietnam
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Oral Hygiene Education Methods
Smartphone App Impact on Oral Hygiene in Orthodontics
This study aimed to compare changes in gingival index (GI), plaque index (PI), and gingival bleeding index (GBI) values in fixed orthodontic patients.
- Trial name
- NCT06865625
- Testing
- mobile application, traditional oral hygiene motivation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Orthodontics, Bracket Bonding
Indirect Bonding Accuracy of 3D Printed Digital Transfer Trays
The goal of this study is to compare the bracket transfer accuracy of two frequently used 3D printed indirect bonding trays. This is an interventional study. Participants have 3-6mm crowding without tooth loss and deformity.
- Conditions
- Orthodontics, Bracket Bonding, Indirect Bonding, Digital Indirect Bonding Transfer Tray
- Trial name
- NCT06167278
- Testing
- Indirect bonding with two different digital bracket bonding transfer tray
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Maxillary Transverse Deficiency Class I Malocclusion Vitamin D Deficiency Orthodontic Tooth Movement Adolescent Health
Effect of Serum Vitamin D on MARPE Treatment Response
A total of 30 patients are planned to be included in the study during the first half of 2025, who will apply to the clinic. In our clinical routine, approximately 30% of RME patients are treated using the MARPE method.
- Trial name
- NCT06943443
- Testing
- Miniscrew-Assisted Rapid Palatal Expansion (MARPE) Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Gingival Recessions, Generalized
Surgical Treatment for Gingival Recessions After Orthodontic Treatment
Modification of the periodontal soft tissue phenotype and coverage of exposed root surfaces in patients who have undergone orthodontic treatment.
- Trial name
- NCT07763808
- Testing
- Coronally advanced flap and a de-epithelialized soft tissue graft, Coronally advanced flap and a subepithelial connective tissue graft, Coronally advanced flap and Mucoderm soft tissue collagen graft
- Where
- Azerbaijan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aziz Aliyev Azerbaijan State Advanced Training Institute for Doctors
Dental Caries
Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients
AIM: To evaluate the efficacy of daily tooth brushing with high concentrated fluoride dentifrice on white spot lesion (WSL) formation in adolescents during treatment with fixed orthodontic appliances (FOA).
- Trial name
- NCT01768390
- Testing
- toothpaste containing 5,000 ppm fluoride, 1450 GCP
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- University of Copenhagen
Non-Pharmacological Pain Management, Orthodontic Discomfort
TENS Device Use for Discomfort Relief During Orthodontic Tooth Movement
The goal of this clinical trial is to learn if Transcutaneous Electric Nerve Stimulation (TENS) device works to reduce discomfort during orthodontic treatment, by using orthodontic separators to mimic the discomfort of braces.
- Trial name
- TENS OTM (NCT07687810)
- Testing
- TENS Device
- Where
- United Arab Emirates
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ajman University
Orthodontic Retention
3D-Printed Vs Thermoformed Retainers: Comparison of Post-Treatment Stability, Changes in Mechanical Properties and Patients' OHRQoL
Following completion of orthodontic treatment, prolonged retention with either part-time or full-time wear of retainers is crucial in preventing relapse.
- Trial name
- NCT05968625
- Testing
- Thermoformed retainers, 3D-printed retainers
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Orthodontic Appliance
Different Music Genres on Anxiety in Orthodontic Patients
The goal of this clinical trial is to learn if Turkish classical music, patient-selected music, and silence have an effect on psychological and physiological anxiety indicators during orthodontic bracket placement.
- Trial name
- NCT07267676
- Testing
- Patient selected music, Turkish classical music
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Kırıkkale University
Orthodontic Appliance Complication
Using Probiotics to Improve Oral Hygiene During Orthodontic Treatment
Fifty patients needing non-extraction-based metallic orthodontic treatment will be divided randomly into the probiotic group and the control group.
- Trial name
- NCT06641960
- Testing
- Probiotics, Traditional treatment
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Crowding of Anterior Mandibular Teeth
Mechanical Properties and Clinical Efficacy of Two Nickel-Titanium (NiTi) Archwires
Objective: to compare the changes of the mechanical properties measured by tensile test and three point bending test of two NiTi archwires (heat-activated and superelastic); when exposed to the oral conditions during the first…
- Trial name
- (NiTi) (NCT03256279)
- Testing
- .014" NiTi heat-activated archwire, .014" NiTi Superelastic archwire
- Where
- Colombia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Fundación Universitaria CIEO
Orthodontic Appliance Complication, Tooth Demineralization
Fluoride Delivery to Prevent White Spots During Orthodontic Treatment
The aim of this 2-armed, parallel, randomised, controlled trial is to assess the effect of different ways of applying fluoride to teeth on the formation of white spots (enamel demineralisation), during orthodontic treatment with…
- Trial name
- FL4OWS (NCT05005689)
- Testing
- Fluoride mouthwash (0.05%; 225ppm)., Tooth Mousse Plus
- Where
- United Kingdom
- Volunteers
- 130 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Palatal Expansion Technique
Investigation of Skeletally Anchored Expansion of the Maxilla
This study aims to compare two different methods for maxillary expansion in adult patients with transverse maxillary deficiency. Participants will receive either miniscrew-assisted rapid palatal expansion (MARPE-MICRO-4).
- Trial name
- NCT07383376
- Testing
- MARPE, SARME
- Where
- Hungary
- Volunteers
- 90 people
- Sponsor
- Semmelweis University