Clinical trials: Orthodontics
Orthodontic Pain
The Effect of Low-level Laser Therapy to Reduce Pain Caused by Orthodontic Separators: A Randomized, Double-blind Place-bo-controlled, Split-mouth Study
Thirty-three (n=33) participants from the Department of Orthodontics and Pediatric Dentistry, University of Szeged will be randomly assigned into two groups.
- Trial name
- SZTEDENT-laser (NCT06816537)
- Testing
- Low Level Laser Therapy, No Interventions
- Where
- Hungary
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Szeged University
Canine Retraction, Piezocision
Comparative Assessment of Maxillary Canine Retraction With and Without Piezocision
Intraoral impressions with alginate will be taken at the start of treatment and plaster casts will be obtained by using ortho plaster.
- Trial name
- NCT07752212
- Testing
- Piezocision, Conventional canine retraction
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
Malocclusion, Quality of Life
The Effect of Malocclusions on Oral Health Related Quality of Life
Malocclusions in adolescents may affect oral health related quality of life. The study aims at; 1. Evaluating two instruments measuring oral health related quality of life; "Child Perceptions Questionnaire 11-14" (CPQ 11-14)…
- Conditions
- Malocclusion, Quality of Life, Orthodontics, Adolescent
- Trial name
- NCT05038865
- Testing
- Malocclusion and Orthodontic Treatment
- Where
- 3 sites in Sweden
- Volunteers
- 675 people, healthy volunteers welcome
- Sponsor
- Malmö University
Orthodontics, Malocclusion
The Use of 2D and 3D Imaging Modalities and Its Influence on Diagnosis and Treatment Planning in Orthodontics
Research questions: 1. Will the panoramic images derived from cone beam CT data give better diagnostic ability than conventional panoramic radiographs? 2.
- Conditions
- Orthodontics, Malocclusion, Impacted Tooth, Cephalometry
- Trial name
- NCT01246830
- Testing
- Panoramic radiograph, Cephalometric radiograph, Cone-beam computed tomography (CBCT)
- Where
- 2 sites in Belgium
- Volunteers
- 32 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Dental Malocclusion
The Accuracy of Computer Software Prediction of Soft Tissue Profile for Patients Undergoing Fixed Orthodontic Treatment
A clinical study to evaluate the accuracy of computer software in predicting soft tissue profile changes in patients undergoing fixed orthodontic treatment
- Trial name
- NCT05978856
- Testing
- Accuracy of computer software in predicting soft tissue profile changes
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
White Spot Lesions
Preventive Potential of Fluoride Sealants in Adolescent Orthodontic Patients
The aim of this trial is to investigate the potential of using an adhesive bonding agent that also acts as a fluoride sealant when placing fixed orthodontic appliances in adolescent patients, as an alternative to regular bonding…
- Trial name
- NCT07691879
- Testing
- Use of a bonding agent to place the orthodontic appliance, Use of fluoride releasing bonding agent to place the orthodontic appliance
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sigmund Freud PrivatUniversitat
Orthodontic Appliance Complication
Wear-documentation and Orthodontic Appliance Compliance
This randomized controlled trial aims to evaluate whether thermosensory wear-time documentation improves patient compliance of removable orthodontic appliances treated in a public health care clinic.
- Trial name
- NCT05213338
- Testing
- Wear-documentation microchip
- Where
- Finland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Tooth Movement
OC and ICTP in Gingival Crevicular Fluid During Piezocision Accelerated Orthodontic Treatment
The aim of this study was to evaluate the tooth movement with and without piezocision with regard to the levels of osteocalcin and cross-linked C-terminal telopeptides of type I collagen in the gingival crevicular fluid.
- Trial name
- NCT04611984
- Testing
- Piezocision, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Marmara University
Orthodontic Appliances
Changes in Pulpal Blood Flow Between Conventional and Self-ligating Fixed Orthodontic Brackets During Leveling and Alignment Stage
Evaluate and compare initial changes in PBF between conventional and self-ligating fixed orthodontic brackets during leveling and alignment stage using 0.016" Nickle titanium (NiTi) and 0.016X0.022" NiTi archwires at different…
- Trial name
- NCT03780764
- Testing
- A Pre-adjusted edgewise brackets: 3M Gemini Unitek, 0.022" Roth prescription brackets, Self- ligating brackets: Unitek™ Gemini SL Self-Ligating Brackets, 0.022" Roth prescription brackets
- Where
- Jordan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Class II Division 1 Malocclusion
Measuring Rate of Anteriors Retraction With Two Different Techniques
Few studies had investigated the effectiveness of segmental retraction. As a result of that, this study was concerned about comparing retraction rate of maxillary incisors between buccal and palatal mini-implant supported…
- Trial name
- NCT05542745
- Testing
- palatal and buccal retraction
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Oral Ulcer
Aloe Vera and Chlorhexidine Against Traumatic Oral Ulcers
The development of gingivitis in patients during orthodontic treatment is widely known, with the characteristic response of gingival inflammation and hyperplasia and traumatic rashes or ulcerations of the oral mucosa derived from…
- Trial name
- NCT03633292
- Testing
- Antiseptic clorhexidine gel (Lacer, Barcelona, Spain), Master formula of aloe vera gel 80%
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Gingival Health
The Effects of Using Water Flosser Versus Interdental Brush on Gingival Health in Patients With Mandibular Bonded Retainer
This randomized controlled trial aimed to investigate and compare the effects of employing a water flosser versus an interdental brush on the gingival health of individuals with mandibular bonded retainers.
- Trial name
- NCT07054203
- Testing
- Water Flosser, Interdental Brush
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Fenestration, Dehiscence
Alveolar Bone Dehiscence and Fenestration Following Accelerated Maxillary Canine Retraction
Alveolar bone loss and fenestration are the most prevalent bone defects that often result in root exposure, gingival recession, and potential treatment relapse or failure.
- Trial name
- NCT06500559
- Testing
- PRP injection, Combined decortication and PRP injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Clear Aligner Orthodontic Treatment, Composite Attachment
Tooth Discoloration and Chairside Handling Time (Bonding-Debonding) in Flowable Versus Packable Composites for Clear Aligner Bonded Attachments: A Randomized Clinical Trial
This randomized split-mouth clinical trial aims to compare two different composite materials used for bonding attachments in clear aligner orthodontic therapy.
- Conditions
- Clear Aligner Orthodontic Treatment, Composite Attachment, Color Stability of Enamel
- Trial name
- NCT07234149
- Testing
- flowable nanohybrid Composite Resin, Packable Microhybrid Composite Resin
- Where
- 2 sites in Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sulaimani
Orthodontic Pathological Resorption of External Root, Complication of Personal Oral Hygiene
Comparison of Oral Hygiene & Root Resorption During Orthodontic Treatment
Orthodontic treatment has been traditionally carried out with fixed appliances involving the use of stainless steel brackets and archwires.
- Trial name
- RCT (NCT02745626)
- Testing
- Appliance
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- UConn Health
Gingival Recession, Orthodontic Treatment
Gingival Recessions in Orthodontically Treated and Untreated Adult Patients
To identify the predisposing parameters for gingival recessions in adult patients seeking orthodontic treatment. The ultimate aim is to provide a clinical guideline to estimate the risk of developing post-orthodontic gingival…
- Trial name
- NCT07445555
- Testing
- Registration of parameters
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Malocclusion, Malocclusion, Angle's Class
Precision Orthodontics: Virtual Treatment Planning for Orthodontic Braces
The investigators are evaluating the effectiveness of custom-made 3D-printed ceramic (tooth-colored) brackets (braces) compared to conventional tooth-colored brackets (braces).
- Trial name
- NCT04002999
- Testing
- 3D printed ceramic bracket and tray, Stock ceramic bracket + 3D printed tray, Stock bracket, no tray
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Harvard School of Dental Medicine
Orthognathic Surgery, Dentofacial Deformities
Development and Validation of an Automated Three-dimensional Cephalometry Method
This study is aimed to develop and assess the validity of an algorithm for automated three-dimensional cephalometry.
- Trial name
- AutoCEPH-3D (NCT04464252)
- Where
- France
- Volunteers
- 453 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alignment, Leveling and Alignment of Teeth
Improving the Treatment Outcome Related to Inclination of Mandibular Incisors by Separating Aligning and Leveling Phases.
Study Summary The goal of this clinical trial is to determine whether separating the aligning and leveling phases during fixed orthodontic treatment improves the treatment outcome related to the inclination of mandibular incisors…
- Trial name
- Alignment (NCT07733258)
- Testing
- Separating phases of alignment and leveling using heat activated niti archwire
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Orthodontic Treatment, Malocclusion
Intra-oral Evaluation of Force Decay of Pigmented and Transparent Elastomeric Power Chains:
This study aimed to evaluate the amount of force decay in pigmented and transparent elastomeric power chains. The principal investigator measured the amount of force decay at 7 intervals using a calibrated Dentaurum force gauge.
- Trial name
- NCT07300371
- Testing
- Matt gray elastomeric power chains, Matt blue elastomeric power chains, Matt pink elastomeric power chains
- Where
- Yemen
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Sana'a University