Clinical trials: Orthognathic Surgery
Postoperative Care/Methods, Drainage/Methods
The Effect of Manual Lymphatic Drainage on Swelling After Orthognathic Surgery - a Qualitative and 3D Facial Analysis.
Introduction / background Orthognathic surgery is an operation in which one or both jaws are fixed in a more favorable position performed by an osteotomy.
- Conditions
- Postoperative Care/Methods, Drainage/Methods, Edema/Prevention & Control, Orthognathic Surgical Procedures/Adverse Effects
- Trial name
- NCT03682159
- Testing
- manual lymphatic drainage
- Where
- Belgium
- Volunteers
- 26 people
- Sponsor
- University Hospital, Ghent
Mandibular Neoplasms, Maxillary Neoplasms
Three-Dimensional Printing of Patient-Specific Titanium Plates in Jaw Surgery: A Pilot Study
Medical titanium plates are routinely used in fixing mobilized bone segments in jaw surgeries. Generally these plates are commercialized with standard construction specifications.
- Conditions
- Mandibular Neoplasms, Maxillary Neoplasms, Dentofacial Deformities, Maxillofacial Injuries
- Trial name
- 3DJP16 (NCT03057223)
- Testing
- 3D-printed patient-specific titanium plates
- Where
- Hong Kong
- Volunteers
- 96 people
- Sponsor
- The University of Hong Kong
Dentofacial Deformities
Skeletal Stability of Le Fort I Osteotomy Using Patient-specific Osteosynthesis Compared to Mini-plate Fixation for Patients With Dentofacial Disharmony
The aim of the study is to evaluate the Skeletal stability of Le Fort I osteotomy using patient-specific osteosynthesis compared to Mini-plate fixation for patients with skeletal class III malocclusion.
- Trial name
- NCT05340036
- Testing
- Bimaxillary orthognathic surgery using conventional plates, Bimaxillary orthognathic surgery using patient specific plates
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Hassan Fahmy Hassan Alnimr
Craniofacial Abnormalities
Mandibular Slotplates
A new osteosynthesis system for orthognathic surgery was proposed.This system allows small intra-operative adjustments of the bone fragments during the osteosynthesis phase of the operation (also known as the slot principle).
- Trial name
- NCT03679377
- Testing
- Mandibular slotplate
- Where
- Belgium
- Volunteers
- 9 people
- Sponsor
- Universitair Ziekenhuis Brussel
Post Operative Pain, Orthognathic Surgery
Impact of Preemptive Analgesia on Postoperative Pain in Orthognathic Surgery
This randomized controlled clinical trial evaluates the effect of preemptive analgesia on postoperative pain outcomes in adult patients undergoing orthognathic surgery.
- Trial name
- NCT07571252
- Testing
- Acetaminophen, ibuprofen
- Where
- Puerto Rico
- Volunteers
- 72 people
- Sponsor
- University of Puerto Rico
Mandibular Advancement
Sensory Re-Training Following Facial Surgery for Correction of Facial Skeletal Disharmony
The purpose of this study is to determine whether facial exercises in conjunction with opening exercises routinely provided after facial surgery to correct a facial skeletal disharmony will shorten the time until a patient…
- Trial name
- NCT00078507
- Testing
- Sensory Re-training, Sensory Retraining, Opening Exercises
- Where
- 2 sites in United States
- Volunteers
- 186 people
- Sponsor
- University of North Carolina, Chapel Hill
Postoperative Pain
Analgesia Nociception Index in Orthognathic Surgery
This study aims to determine whether goal-directed analgesia using ANI(Analgesia/Nociception Index) can improve the quality of postoperative recovery in patients undergoing maxillofacial surgery.
- Trial name
- NCT06205355
- Testing
- Analgesia/Nociception Index (ANI) monitoring, Standard monitoring
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Hospital
Mandibular Range of Motion, Pain
Early Physiotherapy, Mandibular Motion and Sensorial Recovery After Orthognathic Surgery
Several studies describe that the maximum mandibular opening decreases 60% -70% immediately after orthognathic surgery (OS) and other variables, including laterotrusion, movement speed and facial mimic also decrease drastically.
- Conditions
- Mandibular Range of Motion, Pain, Sensorial Disturbance
- Trial name
- NCT03465033
- Testing
- Early Physiotherapy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of the Basque Country (UPV/EHU)
Orthognathic Surgery
Bupivacaine Liposomal Injectable Suspension, Pain and Narcotic Use After Elective Orthognathic Surgery
This research is being done to determine quantitative and qualitative differences in patients' post-operative pain levels following elective orthognathic surgery after the local administration of a liposomal bupivacaine…
- Trial name
- NCT03318757
- Testing
- Bupivacaine Extended Release Liposome Injection, Bupivacaine HCl
- Where
- United States
- Sponsor
- Boston University
Orthognathic Surgical Procedures
Minimally Invasive Le Fort I Osteotomy
This is a single-center, prospective, randomized, controlled, and double-blind clinical study designed to evaluate the clinical outcomes of the minimally invasive Le Fort I osteotomy (MI-Le Fort I) compared with the conventional…
- Trial name
- NCT07279012
- Testing
- Minimally Invasive Le Fort I Osteotomy, Conventional Le Fort I Osteotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- TC Erciyes University
Pain, Postoperative
Enhanced Recovery With Liposomal Bupivacaine in Orthognathic Surgery
The proposed study design is a prospective, clinical trial comparing control group patients (CG; ncg = 30) that will undergo conventional perioperative management without an ERAS protocol and standard bupivacaine intraoperative…
- Trial name
- NCT03844451
- Testing
- Liposomal Bupivacaine, Bupivacaine and Epinephrine
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
TMD/Orofacial Pain, Malocclusions
Evaluation of the Effects of Orthognathic Surgeries on the Temporomandibular Joint Using a Mandibular Movement Analyzer Device
Condylar position and mandibular motion assessment with digital facebows Arcus Digma III before and after orthognathic surgery.
- Trial name
- NCT07828041
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Semmelweis University
Dentofacial Deformities, Orthognathic Surgery
Quantitative Evaluation of Attention to Faces After Orthognathic Surgery With Eye-tracking
Dentofacial deformities refer to morphological anomalies of the jaws. Their development during growth determines the shape of the lower third of the face and the type of dental occlusion.
- Conditions
- Dentofacial Deformities, Orthognathic Surgery, Social Perception, Eye Tracking
- Trial name
- OCHIRO (NCT06494709)
- Testing
- photographs
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Orthognathic Surgery, Dentofacial Deformities
Development and Validation of an Automated Three-dimensional Cephalometry Method
This study is aimed to develop and assess the validity of an algorithm for automated three-dimensional cephalometry.
- Trial name
- AutoCEPH-3D (NCT04464252)
- Where
- France
- Volunteers
- 453 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Maxillofacial Injuries, Maxillofacial Trauma
Superficial Cervical Plexus Block for Orthognathic Surgery
US-guided superficial cervical plexus block (SCPB) may be used for several head and neck surgeries. Local anesthetic is injected under the sternocleidomastoid muscle for SCPB.
- Conditions
- Maxillofacial Injuries, Maxillofacial Trauma, Maxillofacial Abnormalities, Maxillofacial Dysostosis
- Trial name
- NCT04442009
- Testing
- Group SCPB
- Where
- Turkey (Türkiye)
- Sponsor
- Medipol University
Accuracy, Operation Time
Retrospective Study on the Application of Tooth-bone Dual-support Osteotomy/Location Plate in "Surgery-first" Orthognathic Treatment
The goal of this observational study is to learn the accuracy of tooth-bone dual-support osteotomy/location guide plate compared with conventional CAD/CAM interocclusal splints in "surgery-first" orthognathic surgeries.
- Trial name
- NCT07622758
- Testing
- orthognathic surgery
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College
Pain, Orthognathic Surgery
Effect of Nefopam on Acute Postoperative Pain in Patients Undergoing Orthognathic Surgery
The aim of this study is to determine the analgesic effect of perioperative nefopam on acute pain in patient undergoing orthognathic surgery.
- Trial name
- NCT01461031
- Testing
- nefopam, normal saline (control)
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Orthognathic Surgery, Maxillofacial Abnormalities
Study Evaluating the Performance and Safety of Global D Implants Indicated for Orthognathic Surgery
This study is set up within the framework of the European Union regulation 2017/745 on medical devices. Its objective is to confirm the performance and safety of the Global D implants (ORTRAUTEK® and MINITEK®) used for…
- Conditions
- Orthognathic Surgery, Maxillofacial Abnormalities, Maxilla Fracture
- Trial name
- CMF-ORTHO (NCT05271383)
- Testing
- Orthognathic surgery using Global D's implants.
- Where
- France
- Volunteers
- 198 people
- Sponsor
- Global D
Facial Asymmetry, Retrognathism
Efficacy of Intravenous Iron Therapy in Maintaining Hemoglobin Concentration on Patients Undergoing Bimaxillary Orthognathic Surgery
The aim of this study is to evaluate the effect of Intravenous iron isomaltoside on maintaining hemoglobin concentration in patients undergoing bimaxillary orthognathic surgery.
- Conditions
- Facial Asymmetry, Retrognathism, Prognathism
- Trial name
- NCT03094182
- Testing
- Iron Isomaltoside 1000, Normal saline
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Health-related Quality of Life, Dentofacial Deformities
Cross Cultural Adaptation and Validation of Orthognathic Quality of Life Questionnaire (OQLQ)
The aim of this study was to develop a Spanish version of the Orthognathic Quality of Life Questionnaire (OQLQ) that is conceptually equivalent to the original questionnaire, as well as acceptable, reliable, valid, and responsive…
- Trial name
- NCT04863170
- Testing
- orthognathic surgery
- Where
- Chile
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hospital Carlos Van Buren