Clinical trials: Orthopaedic
Angulation Deformity of Long Bone (Disorder), Acquired Deformity of Knee Joint (Disorder)
Use of Motion Sensors in Correction Procedures of Long Bone Deformities in the Pediatric Age Group
Motion sensors will be used in long bone deformity surgery in pediatric patients. In patients whose deformity status is determined before the surgery, 2 wires will be placed in the same plane from the proximal and distal of the…
- Trial name
- NCT06516497
- Testing
- Group using traditional method in long bone deformity correction, Group using computer-aided sensors in long bone deformity correction
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ataturk University
Knee Deformity
Clinical Study to Evaluate Adaptos®Ortho Wedge Bone Graft Substitute in High Tibial Osteotomy
The aim of this study is to obtain performance and safety data of the new investigational device, dual-part Adaptos®Ortho Wedge, for its intended use in orthopaedic surgery.
- Trial name
- NCT05570760
- Testing
- Adaptos®Ortho Wedge (bone grafting surgery), OWHTO without bone grafting, chronOS® Wedge (bone grafting surgery)
- Where
- 6 sites in Finland, Hungary
- Volunteers
- 87 people
- Sponsor
- Biomendex Oy
Anesthesia, Local
Combined Intravenous Dexamethasone and Dexmedetomidine as Adjuncts to Popliteal and Saphenous Nerve Blocks in Patients Undergoing Orthopaedic Surgery of the Foot and Ankle
The investigators will investigate the beneficial and harmful effects of combining dexamethasone (12 mg) and dexmedetomidine (1mcg/kg) as adjuncts to popliteal and saphenous nerve blocks in patients undergoing surgery of their…
- Trial name
- ADJUNCT2 (NCT04818749)
- Testing
- Saline, Dexamethasone 12 mg, Dexamethasone 12 mg + dexmedetomidine 1 mcg/kg
- Where
- 2 sites in Denmark
- Volunteers
- 120 people
- Sponsor
- Zealand University Hospital
Patient Satisfaction, Sports Injury
Virtual Phone Visits Compared to In-Person Physical Visits for Post-Operative Follow-Up at a Sports Medicine Clinic
This study will compare patient reported outcomes (PROs) of patients seen at virtual phone visits compared to in-person visits for 6 weeks, 12 weeks, and 6 months post-operative follow up at a sports medicine clinic.
- Conditions
- Patient Satisfaction, Sports Injury, Surgery, Orthopedic Disorder
- Trial name
- NCT05998148
- Testing
- virtual phone appointment visits
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Jonathan Wu
Bone Neoplasms, Musculoskeletal Neoplasms
Predicting Allograft Volume in Orthopedic Oncology: Hemielipsoid Formula vs Intraoperative Fluid-Fill Measurement
Bone defects following primary musculoskeletal tumor resection are frequently reconstructed using structural allografts. Allograft availability is limited, and intraoperative waste due to oversized graft selection remains a…
- Conditions
- Bone Neoplasms, Musculoskeletal Neoplasms, Bone Transplantation
- Trial name
- PREDALL (NCT07653178)
- Testing
- Hemielipsoid Formula-Based Preoperative and Intraoperative Bone Defect Volume Estimation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Sakarya University
Constipation, Orthopedic Disorder
Effect of Pre-Surgery Constipation Podcast: A RCT
In this study, the investigators will evaluate the effect of a podcast on constipation on the number of patients with constipation.
- Trial name
- NCT06877078
- Testing
- Constipation information via Podcast
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Central Jutland Regional Hospital
Musculoskeletal Diseases
Development and Validation of an Orthopedic Visit Prompt List
Investigators are interested to see whether patients who received a visit question prompt list before the consultation ask more questions, feel more actively involved in their healthcare, and think of their surgeon as being more…
- Trial name
- NCT04947878
- Testing
- Prompt list
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Texas at Austin
Postoperative Pain, Acute
Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries
Tourniquet, a compressing device, otherwise its use in intravenous regional anesthesia, is commonly used in particular orthopedic surgeries.
- Trial name
- K-IVRAg (NCT05543785)
- Testing
- Ketorolac, Control
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Mansoura University
Pain, Postoperative, Orthopedic Procedures
A Randomized, Open-Label, Single-Dose, Small Study to Evaluate the Safety and Effectiveness of Hydromorphone in Patients With Short Term, Moderate to Severe Postoperative Pain
The purpose of this small study was to investigate the safety and effectiveness of OROS hydromorphone HCI for the treatment of short-term, moderate to severe postoperative pain following total knee replacement surgery.
- Conditions
- Pain, Postoperative, Orthopedic Procedures, Analgesia
- Trial name
- NCT00411307
- Testing
- OROS hydromorphone HCI
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alza Corporation, DE, USA
Pneumonia, Urinary Tract Infections
Prehospital Assessment Units - a Matched Cohort Study
This study aimed to evaluate the prehospital assessment unit (PAU) by admission within 48 hours, 7 days, respectively and on survival.
- Conditions
- Pneumonia, Urinary Tract Infections, Fall, Infections
- Trial name
- NCT05654909
- Testing
- Prehospital assessment unit
- Where
- Denmark
- Volunteers
- 10,849 people
- Sponsor
- Prehospital Center, Region Zealand
Meniscus Lesion, Surveys and Questionnaires
Predicting the Outcome After Treatment of Meniscal Tears
In this study the investigators examined the ability of orthopaedic surgeons to predict the outcome of surgery and non-operative treatment in patients (age 45 to 70) with a non-obstructive meniscal tear.
- Trial name
- NCT03462134
- Testing
- Survey
- Where
- Netherlands
- Volunteers
- 194 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Pain, Pain, Postoperative
Effect of Quranic Recitation and Classical Music on Pain Intensity and Interleukin-6 Levels After Lower Limb Orthopedic Surgery With Intrathecal Anesthesia
The goal of this study is to determine the effect of murottal and classical music on postoperative pain intensity and interleukin 6 levels in patients undergoing lower extremity orthopedic surgery with spinal anesthesia.
- Conditions
- Pain, Pain, Postoperative, Inflammation, Orthopedic Surgical Procedures
- Trial name
- QRCM (NCT06713044)
- Testing
- Murottal Therapy Intervention Name: Murottal (Islamic verse recitation), Classical Music Therapy Intervention Name: Classical Music Listening, Standard Care (in control arm)
- Where
- Indonesia
- Volunteers
- 33 people
- Sponsor
- Universitas Jenderal Soedirman
Outpatient Orthopedic Surgery
Preoperative Education for Less Outpatient Pain After Surgery (PELOPS)
In 2015, more than 50% of surgical procedures were performed in outpatient settings. Successful pain management after outpatient surgery is crucial, and requires a perfect cooperation between caregivers and patients, with clear…
- Trial name
- PELOPS (NCT03754699)
- Testing
- Educational intervention, Standard information
- Where
- France
- Volunteers
- 412 people
- Sponsor
- Hospices Civils de Lyon
Deformity of Bone
Archive of Custom-made Guides for Orthopedic Surgery
The present study aims to design, develop and test an electronic archive to be able to track over time the so-called Patient-Specific Cutting Guides for Orthopedics (in English often known as ' Pa-tient-Specific Cutting Guides').
- Trial name
- NCT07893132
- Testing
- Archive
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Ortopedico Rizzoli
Surgery, Acute Phase Reaction
Neuroinflammation and Cognitive Dysfunction After Orthopedic Surgery
The primary hypothesis that orthopaedic surgery induces a neuroinflammatory response within 48 hours after elective hip or knee surgery and that there is an association between exaggerated CNS inflammatory response or impaired…
- Trial name
- NCT02759965
- Where
- 2 sites in Sweden
- Volunteers
- 34 people
- Sponsor
- Karolinska University Hospital
Shoulder Injuries and Disorders, Shoulder Pain
Evaluation of Extended Scope Physiotherapists in an Orthopaedic Outpatient Shoulder Clinic
This study investigates the agreement between extended scope physiotherapists (ESP) and orthopaedic surgeons (OS) on diagnosis and treatment plan in an orthopaedic outpatient shoulder clinic.
- Conditions
- Shoulder Injuries and Disorders, Shoulder Pain, Musculoskeletal Pain
- Trial name
- NCT03343951
- Testing
- Examination
- Where
- Denmark
- Volunteers
- 69 people
- Sponsor
- Central Jutland Regional Hospital
Bone Tumor, Bone Cancer
Pediatric Oncological Orthopaedic Reconstruction
From the archives of the Rizzoli institute all the children undergoing oncological reconstruction from 1991 to 2023 (approximately 400 patients).
- Trial name
- NCT06522165
- Testing
- Analysis
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Costantino Errani
Total Fluid Volume Increased
Evaluate the Nephrotoxicity by 6% Hydroxyethyl Starch 130/0.4 in Old Patients During Orthopaedic Surgery
Hydroxyethyl starch (HES) is commonly used as plasma expander during surgery but may be nephrotoxic as seen in studies in patients with sepsis.
- Trial name
- NCT02361736
- Testing
- Hydroxyethyl Starch, Lactate Ringers
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Yuanyuan Zhang
Orthopedic Surgery
The Effect of Progressive Relaxation Exercise on Fatigue and Comfort Level After Major Orthopedic Surgery
This study was planned to determine the effect of progressive relaxation exercise to be applied after major orthopedic surgery on post-operative fatigue and comfort level.
- Trial name
- NCT05295199
- Testing
- Progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Aksaray University
Orthopedic Disorders
The Different Analgesic Potency of Volatile Anesthetics at Equi-MAC
The aim of this clinical trial is to evaluate the difference of analgesic potency of sevoflurane and desflurane at equi-minimum alveolar concentration using a surgical pleth index.
- Trial name
- NCT02609802
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 77 people
- Sponsor
- Kangbuk Samsung Hospital