Clinical trials: Orthopaedic Trauma
Degenerative Arthritis of Left Glenohumeral Joint, Degenerative Arthritis of Right Glenohumeral Joint
Costs and Consequences of Three Common Orthopedic Procedures on the Upper Extremity
This study compares costs and effectiveness / utility of three common orthopedic surgeries in shoulder and hand from the perspective of the Swiss health system and the clinic.
- Conditions
- Degenerative Arthritis of Left Glenohumeral Joint, Degenerative Arthritis of Right Glenohumeral Joint, Rotator Cuff Tear Arthropathy, Rotator Cuff Tear
- Trial name
- NCT01954433
- Testing
- Operated TSA Patients, Operated RCR Patients, Resection interposition suspension arthroplasty (RISA)
- Where
- Switzerland
- Volunteers
- 450 people
- Sponsor
- Schulthess Klinik
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS)
Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test
The goal of this clinical trial is to understand how people make decisions about imaging tests for common musculoskeletal problems (like arthritis, tendon problems, or nerve compression).
- Conditions
- Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis
- Trial name
- NCT07158892
- Testing
- Diagnostic Advance Care Planning Discussion, Informational Statement Only
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Texas at Austin
Surgical Wound Infection
Wound Infections Following Implant Removal
In the Netherlands about 18,000 surgical procedures with implant removal are annually performed after fracture healing, of which 30-80% concern the foot, ankle and lower leg region.
- Trial name
- WIFI (NCT02225821)
- Testing
- Cephalozin, Sodium chloride
- Where
- 21 sites in Netherlands
- Volunteers
- 500 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Surgical Site Infection
Investigation of Environmental Parameters in Operating Rooms
Postoperative surgical site infection (SSI) is a serious and complicated healthcare-associated infection (HAI) affecting about 2% of patients undergoing orthopedic surgery.
- Trial name
- NCT05816135
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Sahlgrenska University Hospital
Sleep Disturbance, Trauma
Treatment for Sleep Disturbance in Orthopaedic Trauma Patients
The purpose of the study is to test the efficacy of sleep treatment in human patients following traumatic injury. Specifically, the study will determine if treatment consisting of melatonin and education related to sleep habits…
- Trial name
- NCT03779243
- Testing
- Melatonin 5mg and Sleep Education
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Stanford University
Orthopedic Surgery
Pain Relief After Forefoot Surgery
The aim to test whether continues local anaesthetic infusion via tibial catheter or wound catheter will improve pain relief following forefoot surgery In this sequential prospective randomised, controlled clinical trial,75…
- Trial name
- NCT01019005
- Testing
- Catheter
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Spondylosis, Cervical, Spinal Cord Compression
Validity of the Turkish Translation of the Modified JOA
Degenerative cervical myelopathy (DCM) is the most common cause of non-traumatic spinal cord dysfunction in adults and may lead to progressive motor, sensory, and autonomic impairment.
- Trial name
- NCT07448883
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Izmir Democracy University
Geriatric Patients, Postoperative Complications
PREDICTING MINS WITH FRAILTY AND BIOMARKERS IN GERIATRIC SURGERY
The primary objective of this study is to develop and validate a machine learning model that integrates preoperative clinical data, biomarkers, and modified frailty indices (mFI-5) to accurately predict myocardial injury after…
- Conditions
- Geriatric Patients, Postoperative Complications, Frailty, Myocardial Ischemia
- Trial name
- NCT07566013
- Testing
- Preoperative Risk Assessment and Machine Learning Modeling
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- DİLEK KALAYCI
Orthopaedic Trauma
rTMS for Orthopaedic Trauma Patients
This study evaluates an accelerated schedule of theta-burst stimulation using a transcranial magnetic stimulation device for orthopaedic trauma patients.
- Trial name
- NCT03924024
- Testing
- Accelerated intermittent theta burst treatment
- Where
- United States
- Sponsor
- Stanford University
Orthopedic Disorder, Anxiety
Brachial Plexus Block vs. General Anesthesia for Anesthesia Anxiety Before Orthopedic Upper Extremity Surgery
Surgical procedures and anesthesia applications are situations in which people do not feel safe due to the current vital risks. Anxiety is a natural reaction that occurs in such situations, it manifests itself with worry and…
- Conditions
- Orthopedic Disorder, Anxiety, Upper Extremity Injury, Surgery
- Trial name
- NCT05476198
- Testing
- Brachial plexus block, General anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Ankle Fractures, Orthopedic Procedures
Outpatient Versus Inpatient Surgery for Ankle Fractures
This study is a single center randomized controlled trail in which we compare outpatient and inpatient patients with an ankle fracture requiring surgical treatment.
- Conditions
- Ankle Fractures, Orthopedic Procedures, Surgical Procedures, Inpatient
- Trial name
- OVISAF (NCT05389436)
- Testing
- Ambulatory care, Inpatient care
- Where
- Denmark
- Volunteers
- 86 people
- Sponsor
- Christian Grundtvig Refstrup Rasmussen
Nociceptive Pain, Pain, Postoperative
Guiding Opioid Administration in Patients With Regional Anesthesia
General anesthesia is a combination of hypnotic drugs to achieve unconsciousness and opioid analgesics to ensure antinociception.
- Conditions
- Nociceptive Pain, Pain, Postoperative, Analgesia, Anesthesia Recovery Period
- Trial name
- GORA (NCT06040307)
- Testing
- SPI (Surgical Pleth Index)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Staphylococcus Aureus Infection, Surgical Site Infection
Serum Based Diagnosis of and Monitoring of Infection Recovery in Orthopedic Spine Implant Infections
The goal of this study is to test a new way to diagnose and track treatment of spine infections caused by the bacteria Staphylococcus aureus.
- Conditions
- Staphylococcus Aureus Infection, Surgical Site Infection, Orthopedic Procedures, Spine
- Trial name
- NCT04897971
- Testing
- Medium enriched for newly synthesized antibodies in spine infection
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Colorado, Denver
Open Fracture
Preventing Infections in Orthopaedic Patients
Determine if antibiotic prophylaxis with intravenous cephalosporin and aminoglycoside in patients with Type II and II open fractures is safe and effective.
- Trial name
- NCT02948387
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Olayemi Osiyemi MD
Hip Pain Chronic, Femoro Acetabular Impingement
Education and Exercise for Patients With Longstanding Hip and Groin Pain
Longstanding hip and groin pain (LHGP) is a common and debilitating problem in young to middle aged individuals. These patients often get referred to orthopedic departments.
- Conditions
- Hip Pain Chronic, Femoro Acetabular Impingement, Groin Injury
- Trial name
- HIPSTER (NCT05853640)
- Testing
- Usual care, HIPSTER
- Where
- Sweden
- Volunteers
- 122 people
- Sponsor
- Lund University
Proximal Femoral Fracture, Dinamic Hip Surgery
Motion Graphic Training for Scrub Nurses in Hip Surgery
This pilot randomized controlled trial evaluates the effect of motion graphic video-based training on the performance of scrub nurse students during dynamic hip screw (DHS) surgery.
- Trial name
- NCT07701564
- Testing
- Motion Graphic Video Training, Routine Clinical Training
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arak University of Medical Sciences
Lower Extremity Injury
Improving Recovery After Orthopaedic Trauma: Cognitive-Behavioral Based Physical Therapy (CBPT)
The goal of the CBPT study is to determine the efficacy of the CBPT program for improving outcomes in service members and civilians at-risk for poor outcomes following traumatic lower-extremity injury.
- Trial name
- CBPT (NCT03335657)
- Testing
- CBPT, Education Treatment
- Where
- 8 sites in United States
- Volunteers
- 633 people
- Sponsor
- Major Extremity Trauma Research Consortium
Surgical Wound Infection
Sutures Versus Staples for Wound Closure in Orthopaedic Surgery
The trial is a randomized, controlled trial. Adult patients undergoing orthopaedic surgical procedures would be randomized to one of two groups for surgical wound closure, skin sutures or skin staples.
- Trial name
- NCT01146236
- Testing
- Sutures, Staples
- Where
- 3 sites in Canada
- Volunteers
- 247 people
- Sponsor
- University of Manitoba
Hip Fracture
Does Tranexamic Acid Reduce the Need for Blood Transfusions in Patients Undergoing Hip Fracture Surgery?
Does tranexamic acid improve the perioperative care of those patients treated surgically for hip fracture by decreasing the proportion of patients requiring transfusion and decreasing total perioperative bleeding.
- Trial name
- NCT01714336
- Testing
- tranexamic acid
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Mayo Clinic
Orthopedic Disorder
Open Reduction Internal Versus Percutaneous Sacroiliac Screw Fixation in Unstable Posterior Ring Injury of Pelvic
Surgical trearment of unstable posterior pelvic injuries can be performed with open reduction and internal fixation, closed reduction with percutaneous sacroiliac fixation.
- Trial name
- NCT05473611
- Testing
- closed reduction percutaneous fixation with open reduction internal fixation of the posterior pelvic ring
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ataturk University