Clinical trials: Orthopedic Injury
Orthopedic Disorder, Fractures, Bone
Efficacy of Virtual Reality in Pain Reduction in Orthopedic Pediatric Patients
To prospectively determine if pediatric patients undergoing orthopedic procedures can benefit from employing virtual reality for pain management.
- Trial name
- NCT04901793
- Testing
- Virtual Reality Headset and handheld remote control.
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Ochsner Health System
Staphylococcus Aureus, Surgical Wound Infection
Risk Factors for Staphylococcus Aureus Surgical Site Infections in Orthopedic and Trauma Surgery
The most commonly identified organism for Surgical Site Infection (SSI) in orthopedic surgery is Staphylococcus aureus but risk factors for mono microbial S.aureus SSI are not well-known.
- Conditions
- Staphylococcus Aureus, Surgical Wound Infection, Orthopedic Disorder, Traumatology
- Trial name
- ISO (NCT03040960)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Grenoble
Pain, Postoperative
Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia
The purpose of this study is to determine whether, for surgery of the tibia, one dose of methadone provides better control of pain afterward as compared to morphine, which is the usual drug given to control pain after surgery.
- Trial name
- NCT01430182
- Testing
- Methadone, Morphine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Baylor College of Medicine
Trauma Injury
ICG Fluorescence Imaging in Open Fracture Trauma Patients
This is a prospective observational study that will evaluate the association between bone and tissue perfusion, as measured by indocyanine green (ICG) fluorescence imaging, and complications, in an effort to develop ICG…
- Trial name
- NCT04416412
- Testing
- Immunofluorescence Imaging
- Where
- 4 sites in United States
- Volunteers
- 124 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Fractures, Bone, Dislocations
Prospective Abuse and Intimate Partner Violence Surgical Evaluation
Intimate partner violence (IPV), also known as domestic abuse, is a leading cause of non-fatal injury in women worldwide. 1 in 6 women attending surgical fracture clinics have a history of IPV in the past year.
- Conditions
- Fractures, Bone, Dislocations, Spouse Abuse
- Trial name
- PRAISE-2 (NCT02529267)
- Testing
- Standard of care
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- McMaster University
Rupture of Anterior Cruciate Ligament, Osteoarthritis
Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction (ACLR): Onsite Follow-up
In this study we will examine patients who have undergone unilateral ACL reconstruction surgery to determine which structural and functional characteristics of the knee two and ten years post reconstruction surgery, aspects of…
- Trial name
- MOON-Onsite (NCT00478894)
- Where
- 4 sites in United States
- Volunteers
- 432 people
- Sponsor
- Vanderbilt University
Carpal Tunnel Syndrome
Length of Post Operative Dressing After Carpal Tunnel Release
The purpose of the study is to prospectively compare the functional, satisfaction, and wound outcomes of patients treated with one of two accepted methods of postoperative dressing following carpal tunnel release.
- Trial name
- NCT01310218
- Testing
- extended postoperative dressing, short postoperative dressing
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- UConn Health
Hip Fracture, Myocardial Ischemia
Pilot Study of Atorvastatin for Orthopedic Surgery Patients
Up to 35% of hip fracture patients have been shown to experience heart injury after surgery, and as many as 10% have a heart attack or die in the three months after surgery.
- Conditions
- Hip Fracture, Myocardial Ischemia, Inflammation
- Trial name
- POST-OP Pilot (NCT02197065)
- Testing
- Atorvastatin
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Hospital for Special Surgery, New York
Ankle Fracture, Ankle Sprain
Applicability of the Ottawa Ankle Rules
The aim of this prospective study was to compare outcomes in patients handled by emergency physician according to OAR versus by an orthopedic resident.
- Trial name
- NCT01561365
- Testing
- Ottawa ankle rules
- Where
- Israel
- Volunteers
- 92 people
- Sponsor
- Hadassah Medical Organization
Traumatic Brain Injury, Orthopedic Injury
Epigenetic Effects on Traumatic Brain Injury Recovery
Methylation of the brain-derived neurotrophic factor (BDNF) gene is involved in both the biological encoding of childhood adversity and neuroplasticity following traumatic brain injury (TBI).
- Trial name
- EETR (NCT04186429)
- Where
- United States
- Volunteers
- 401 people
- Sponsor
- University of Pittsburgh
Trauma, COVID-19 Pandemic
The Impact of the Covid-19 Pandemic on Orthopedic Trauma Management
The aim of the study is to compare emergency orthopedic trauma admissions between the pre-pandemic period and the pandemic period and to detect changes in orthopedic trauma epidemiology.
- Trial name
- NCT06237023
- Testing
- epidemyolojical
- Where
- Turkey (Türkiye)
- Volunteers
- 57,635 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Surgical Site Infection, Microbial Colonization
Broad-spectrum Antibiotic Prophylaxis in Tumor and Infected Orthopedic Surgery
The perioperative antibiotic prophylaxis is evidence-based in orthopedic surgery. While its duration ranges from a single dose to three doses throughout the world, the choice of the prophylactic agents is undisputed.
- Conditions
- Surgical Site Infection, Microbial Colonization, Antibiotic Resistant Infection
- Trial name
- BAPTIST (NCT05502380)
- Testing
- Standard antibiotic prophylaxis
- Where
- Switzerland
- Volunteers
- 1,100 people
- Sponsor
- Balgrist University Hospital
Rotator Cuff Tears, Postoperative Pain
The Effect of Liposomal Bupivacaine Nerve Block (Exparel) in Rotator Cuff Surgery
The goal of this clinical trial is to investigate if there is a difference in pain after an arthroscopic rotator cuff surgery when a nerve block is performed with liposomal bupivacaine versus the standard treatment of bupivacaine…
- Conditions
- Rotator Cuff Tears, Postoperative Pain, Opioid Use
- Trial name
- NCT06139666
- Testing
- Exparel Injectable Solution, Bupivacaine Injectable Solution
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- The Cooper Health System
Radius; Deformity, Hip Osteoarthritis
Clinical Evaluation and Cost-effectiveness Analysis of 3D Digital Surgery in Traumatology
Digital surgery, in combination with patient specific instrumentation (PSI) is being used more and more in traumatology due to its proven benefits and applications.
- Conditions
- Radius; Deformity, Hip Osteoarthritis, Hip Arthritis, Hip Arthropathy
- Trial name
- NCT06603831
- Testing
- patients treated using 3D technology and Patient-Specific Instrumentation, Patients treated with conventional surgery, without using 3D technology
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Corporacion Parc Tauli
Arthroscopy, Tibial Fractures
Arthroscopic Assisted Balloon Tibioplasty for the Treatment of Schatzker II-IV Tibial Plateau Fractures
The investigators use existing resources to carry out this new technology, in accord with the standard of the patients, were randomized to traditional fracture balloon tibia fixation or arthroscopic reduction under angioplasty…
- Conditions
- Arthroscopy, Tibial Fractures, Orthopedic, Fracture Fixation
- Trial name
- AABTFTPF (NCT03327337)
- Testing
- Arthroscopic Assisted Balloon Tibioplasty
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Orthopaedic Trauma
rTMS for Orthopaedic Trauma Patients
This study evaluates an accelerated schedule of theta-burst stimulation using a transcranial magnetic stimulation device for orthopaedic trauma patients.
- Trial name
- NCT03924024
- Testing
- Accelerated intermittent theta burst treatment
- Where
- United States
- Sponsor
- Stanford University
Amyotrophic Lateral Sclerosis, Muscular Dystrophy
Innovative Ultrasound Technology in Neuromuscular Disease
This study is utilizing ultrasound measurement to measure neuromuscular disease status in adult patients. The hypothesis is the by quantifying ultrasound data, it is possible that ultrasound can be utilized as a tool to determine…
- Conditions
- Amyotrophic Lateral Sclerosis, Muscular Dystrophy, Radiculopathy, Myopathy
- Trial name
- AQUIRe (NCT02104921)
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Shoulder and Elbow Injury
TRANSLATION, ADAPTATION, VALIDATION AND RELIABILITY OF ARABIC VERSION OF KERLAN-JOBE ORTHOPAEDIC CLINIC SHOULDER AND ELBOW SCORE IN EGYPTIAN SYMPTOMATIC OVERHEAD ATHLETES
PURPOSE: To perform a cross-cultural adaption of the KJOC Shoulder and Elbow score into the Arabic language, then to test its validity and reliability.
- Trial name
- Ar-KJOC (NCT07729306)
- Testing
- Questionnaire and Physical Exam
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ziad Mohamed Mohamed Abdalla Haroun
Intraoperative Hypotension, Acute Kidney Injury
Non-invasive Measurement of the Hypotension Prediction Index for the Reduction of Intraoperative Hypotension
In order to reduce the incidence of IOH, various goal-directed therapy (GDT) protocols have already been introduced with success regarding the reduction of postoperative AKI and MINS.
- Conditions
- Intraoperative Hypotension, Acute Kidney Injury, Myocardial Injury After Non-cardiac Surgery
- Trial name
- Clearsight (NCT06291714)
- Testing
- GDT-based hemodynamic management based on Clearsight device
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- University of Giessen
Deep Vein Thrombosis, Venous Thromboembolism
Deep Vein Thrombosis Prophylaxis Adherence: Enoxaparin vs Rivaroxaban
The objective of this study is to compare oral rivaroxaban with injectable enoxaparin in orthopaedic trauma patients to determine if orally administered rivaroxaban once daily carries greater compliance and overall satisfaction…
- Trial name
- NCT04169269
- Testing
- Enoxaparin 40 milligram/0.4 milliliter Injectable Syringe 0.4 milliliters, Rivaroxaban 10 milligram Oral Tablet
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Florida Orthopaedic Institute