Clinical trials: Orthopedic Injury
Surgical Site Infection (SSI)
Sterile vs Clean Non-Sterile Wound Dressing in Orthopedic Surgery
This randomized interventional pilot study aims to compare the rate of significant Surgical Site Infection (SSI) within the six weeks after elective orthopedic surgery using sterile versus clean non-sterile glove postoperative…
- Trial name
- NCT07436065
- Testing
- Sterile Glove Dressing Technique, Clean Non-Sterile Glove Dressing Technique
- Where
- Qatar
- Volunteers
- 25 people
- Sponsor
- Hamad Medical Corporation
Hip Fracture, Myocardial Ischemia
Pilot Study of Atorvastatin for Orthopedic Surgery Patients
Up to 35% of hip fracture patients have been shown to experience heart injury after surgery, and as many as 10% have a heart attack or die in the three months after surgery.
- Conditions
- Hip Fracture, Myocardial Ischemia, Inflammation
- Trial name
- POST-OP Pilot (NCT02197065)
- Testing
- Atorvastatin
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Hospital for Special Surgery, New York
Surgical Site Infection, Vancomycin
Pharmacokinetics of Preoperative Vancomycin
A study of plasma and tissue vancomycin pharmacokinetics in pediatric surgical patients.
- Trial name
- NCT03453684
- Testing
- Administration of Vancomycin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Tibial Fracture
Assessment of the Verus Frame in Tibial Intramedullary Nailing
This prospective, single-arm Post-Market Clinical Follow-Up (PMCF) study, utilizing a registry-based control group, will assess the Verus frame's effectiveness in achieving precise tibial rotation and alignment during…
- Trial name
- NCT07362121
- Testing
- Verus frame to stabilize tibia
- Where
- Finland
- Volunteers
- 25 people
- Sponsor
- Hemitec Finland Oy
Rupture of Anterior Cruciate Ligament
Multicenter Orthopaedics Outcomes Network for ACL Reconstructions
The purpose of this study is to determine the effect of modifiable risk factors on knee function, osteoarthritis, and re-rupture of the anterior cruciate ligament (ACL) following ACL reconstruction.
- Trial name
- NCT00463099
- Where
- 8 sites in United States
- Volunteers
- 3,294 people
- Sponsor
- Vanderbilt University Medical Center
Postoperative Pain, Postoperative Cognitive Dysfunction
S-ketamine Prevents Postoperative Pain and Cognitive Dysfunction After Tibial Fracture
Purpose: To explore effects of S-ketamine on postoperative pain and cognitive dysfunction after tibial fracture and orthopedic surgery.
- Trial name
- NCT04643132
- Testing
- Normal saline, S-ketamine (low-dose), S-ketamine (high-dose)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tianjin Medical University General Hospital
Motor Impairments, Orthopaedic Injuries
Gait Characteristics Following a Fall
The purpose of this study is to quantify the safety degree of the patient's gait, to detect the reason for the fall and quantify the biomechanical parameters related to fall.
- Conditions
- Motor Impairments, Orthopaedic Injuries, Neurological Conditions
- Trial name
- NCT01631604
- Testing
- Walking aids and devices, Muscle/nerve injection, Corrective surgery
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Surgical Site Infection
Nasal Decolonization for Orthopedic Trauma Patients
Many surgical site infections are caused by bacteria that is transferred from a patient's nose to their open surgical wound. Some small studies have shown that putting povidone-iodine in a patient's nose reduces this risk.
- Trial name
- NCT04146116
- Testing
- intranasal povidone-iodine
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Iowa
Radius Fractures
Orthopedic Study of the Aircast StabilAir Wrist Fracture Brace
Objectives: To obtain clinical evidence for the safety and efficacy in using the StabilAir Wrist Fracture Brace for the following cases: 1.
- Trial name
- NCT00587795
- Testing
- StabilAir Wrist Brace, Placement of sugar tong splint or plaster cast
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Fractures, Closed, Wounds and Injuries
Antibiotic Prophylaxis in Orthopaedic Traumatology
It has been established that providing antibiotic prophylaxis after closed fracture fixation with implants or prosthetic devices has beneficial effects.
- Trial name
- NCT00610987
- Testing
- cefazolin
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- University of Missouri-Columbia
Pain, Anxiety
Mobilization Protocol for Knee Arthroplasty Patients
This randomized controlled study evaluates the effect of mobilization protocol applied to knee arthroplasty patients on anxiety level, pain, mobility and functional status.
- Conditions
- Pain, Anxiety, Physical Function, Mobility
- Trial name
- KA-Mobility (NCT05679947)
- Testing
- Mobilization protocol
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Gazi University
Diabetic Foot, Orthopedic Disorder
Clinical Efficacy of a 3D Foot Scanner for the Therapeutic Footwear Fitting
Patients with diabetes at high risk of ulceration require a perfect fitting shoe to avoid high shear and pressure forces. Neuropathy skews sensory perceptions and can alter the proper selection of the therapeutic footwear.
- Conditions
- Diabetic Foot, Orthopedic Disorder, Foot Ankle Injuries
- Trial name
- Smartfitting (NCT05353114)
- Testing
- 3D feet scan (smart-fitting by Podiapp - Podartis s.r.l Unipersonale-Crocceta del Montello (TV), Italy).
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Orthopedic Disorders, Injury of Anterior Cruciate Ligament
Injection Pressure & Adductor Canal Block
This is a prospective, randomized, single-blinded human clinical trial that will examine how injection pressure influences the spread of a given volume of injectate in the adductor canal, during adductor canal nerve block.
- Trial name
- NCT02563990
- Testing
- High Pressure Injection, Low Pressure Injection
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Miami
Severe Orthopedic Trauma
Improving Activity and Quality of Life Following Orthopaedic Trauma: The Trauma Collaborative Care Study (TCCS)
The study uses a multi-site, cluster design to determine the effectiveness of an intervention based on a Trauma Collaborative Care (TCC) model in improving patient outcomes for persons with severe orthopedic trauma and enhancing…
- Trial name
- TCCS (NCT01907893)
- Testing
- Trauma Collaborative Care Plus Treatment as Usual
- Where
- 13 sites in United States
- Volunteers
- 900 people
- Sponsor
- Major Extremity Trauma Research Consortium
Coronavirus Infection, Orthopedic Disorder
Retrospective Case Series of COVID19+ Patients Undergoing Orthopedic Surgery
Over the last months, the Rizzoli Orthopedic Institute in Bologna, Italy, has drained orthopedic urgencies from all other hospitals in the urban and suburban area.
- Conditions
- Coronavirus Infection, Orthopedic Disorder, Bone Fracture, Bone Metastases
- Trial name
- COVID19&SURG (NCT05881343)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Ortopedico Rizzoli
Lower Extremity Fracture
The Effect of Tele-Nursing Application on Self-Care Ability and Daily Living Activities in Fracture Surgery Patients
This study aims to determine the effect of tele-nursing application based on Orem's Self-care Theory on self-care agency and daily living activities in trauma-related lower extremity fracture surgery patients.
- Trial name
- NCT06284759
- Testing
- post-discharge telenursing intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Gazi University
Delirium
Supporting the Health of Adults Undergoing Orthopedic Surgery During the Recovery Period
Delirium (acute confusion) is a highly prevalent condition among hospitalized elders with substantial morbidity within the hospital and beyond.
- Trial name
- SHARP (NCT00586196)
- Testing
- donepezil
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Beth Israel Deaconess Medical Center
Proximal Femoral Fracture
Proximal Femur Image Database Validation
The AO@AI Turin project is a collaborative project with a Turin group and the AO (Arbeitsgemeinschaft für Osteosynthesefragen, or in English, Association for the Study of Internal Fixation) foundation.
- Trial name
- NCT06351943
- Testing
- Fracture classification annotations provided by the Turin group, Fracture classification annotations provided by the AO expert surgeon group
- Where
- Switzerland
- Volunteers
- 2,932 people
- Sponsor
- AO Innovation Translation Center