Clinical trials: Orthopedic Injury
Meniscus Injury
Clinical Application Research of Combined Therapy in ERAS for Accelerated Orthopedic Rehabilitation
The double-blind method is adopted.Case selection Patients who underwent meniscus repair surgery under knee arthroscopy at Li Huili Hospital Affiliated to Ningbo University, the 906th Hospital of the People's Liberation Army…
- Trial name
- NCT07273032
- Testing
- Blank control group, Henggu Bone Injury Healing Agent Intervention Group, Lower limb rehabilitation training system intervention group
- Volunteers
- 120 people
- Sponsor
- Ningbo Medical Center Lihuili Hospital
Surgical Wound, Post Operative Wound Infection
Early Versus Delayed Bathing of Orthopaedic Surgical Wounds
This is a single center randomized control trial assessing the effect of early versus delayed bathing on orthopaedic surgical wounds in patients undergoing surgical treatment of fractures.
- Trial name
- EVDB (NCT06014411)
- Testing
- Time to bathing (delayed), Time to bathing (early)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Hospital for Special Surgery, New York
Smoking, Tobacco, Fractures, Bone
Let's STOP Now Trial: Smoking in Trauma Orthopaedic Patients
It is well known that smoking has deleterious effects to fracture/broken bone outcomes. Complications associated with smoking can be mitigated by smoking cessation.
- Trial name
- STOP (NCT02428244)
- Testing
- Motivational Interviewing, Motivational Interviewing + Follow-up
- Where
- United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Athletic Injuries
Foam Rolling and Orthopaedic Manual Physical Therapy in Athletes
The main objective of the present study was to evaluate whether FR massage is effective in improving dynamic balance, flexibility and dynamic strength after intense exercise recovery compared to OMPT protocol or a control group.
- Trial name
- FRvsMTAth (NCT04161300)
- Testing
- Foam Rolling (FR), Control Group (CG), Orthopaedic Manual Physical Therapy Group (OMPT)
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Developmental Dysplasia of Hip, DDH
8 vs 12 Weeks: A Pavlik Harness Trial
Developmental dysplasia of the hip is the most common bone and joint condition in babies. It is usually treated with a harness that holds the hips in a safe position so they can develop normally.
- Conditions
- Developmental Dysplasia of Hip, DDH, Developmental Dysplasia of the Hip, Developmental Dysplasia of the Hip (DDH)
- Trial name
- NCT07847619
- Testing
- Pavlik Harness
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- The Hospital for Sick Children
Hip Fractures, Acute Post Operative Pain
PENG vs SIFI Block for Positioning Pain During Spinal Anesthesia
This study aims to compare the effectiveness of preoperative ultrasound-guided suprainguinal fascia iliaca compartment block (SFICB) and pericapsular nerve group block (PENG) in preventing positioning pain during spinal…
- Conditions
- Hip Fractures, Acute Post Operative Pain, Nerve Block, Spinal Anesthesia
- Trial name
- NCT05549011
- Testing
- PENG Block, SIFI compartment block, Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Supracondylar Humerus Fracture, Post Operative Wound Infection
Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)
The aim of this study is to determine if antibiotics affect the outcome after percutaneous surgery for pediatric supracondylar humerus fractures.
- Trial name
- NCT03261830
- Testing
- Cefazolin, Clindamycin, Saline
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Sumit Gupta
Smoking Cessation, Fracture
Smoking Cessation Intervention in Acute Orthopedic Surgery
The purpose of this study was to evaluate if an intervention with smoking cessation starting during the acute hospitalization period and continuing during the acute postoperative phase of 6 weeks would reduce the frequency of…
- Trial name
- NCT00704015
- Testing
- Smoking cessation
- Volunteers
- 105 people
- Sponsor
- Karolinska Institutet
Ictus, Convalescence
Effectiveness of Laser Visual Feedback in Postural Control After a Stroke
Background: Stroke is one of the leading causes of acquired disability and frequently results in impairments in balance and postural control that affect functional independence.
- Conditions
- Ictus, Convalescence, Rehabilitation by Recovery of Function, Rehabilitation Frail Elderly Subjects
- Trial name
- FV-CP (NCT07811843)
- Testing
- Intervention
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Parc Sanitari Pere Virgili
Pain, Anxiety
Mindfulness Intervention in Orthopedic Trauma Patients
This project a single-site 3-arm parallel group randomized clinical trial conducted at a tertiary level 1 trauma center among patients undergoing operative fixation of a lower extremity fracture.
- Trial name
- NCT05634278
- Testing
- Preoperative mindfulness, Postoperative mindfulness, Mind wandering
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- University of Utah
Hand Fractures
Mirror Therapy and Hand Rehabilitation
Objective: The purpose of this study is to determine effects of mirror therapy in restoring hand function in patients with flexor lag following orthopedic injuries.
- Trial name
- NCT01503762
- Testing
- Mirror therapy, Classical rehabilitation techniques
- Where
- Iran
- Volunteers
- 23 people
- Sponsor
- Ahvaz Jundishapur University of Medical Sciences
Wound Healing Time, Total Hip Arthroplasty (THA)
Wound Healing, Dressing Type, and Dressing Change Frequency in THA
Surgical wound complications following primary total hip arthroplasty remain a significant clinical challenge despite advances in wound care technologies.
- Trial name
- CAP-HIP (NCT07655388)
- Testing
- VACUTEX™ wound dressing, Octenisept® wound care dressing
- Where
- Serbia
- Volunteers
- 90 people
- Sponsor
- Clinical Center of Vojvodina
Osteoarthritis, Osteosarcoma
Clinical Orthopaedic Data Bank (Acute and Chronic)
Data involving orthopaedic conditions and rehabilitation aspects of musculoskeletal and neuromuscular disorders will be collected and stored as part of the normal clinical care of patients seen in the University of Florida (UF)…
- Conditions
- Osteoarthritis, Osteosarcoma, Scoliosis, Cerebral Palsy
- Trial name
- NCT00411060
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- University of Florida
Osteoarthritis, Arthritis
Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction (ACLR): 10 Year Onsite Follow-up
In this study the investigators will examine patients who have undergone unilateral ACL reconstruction surgery to determine which structural and functional characteristics of the knee two and ten years post reconstruction…
- Conditions
- Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases
- Trial name
- NCT02717559
- Volunteers
- 225 people
- Sponsor
- Vanderbilt University Medical Center
Complex Regional Pain Syndromes, Distal Radius Fractures
Prednisone for CRPS in Distal Radius Fracture
Wrist fractures are the most prevalent adult fracture. Complex regional pain syndrome (CRPS) is a common complication that can occur, leading to permanent disability and is costly to the patient and healthcare system.
- Trial name
- NCT06453447
- Testing
- Prednisone
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Trauma Injury
ICG Fluorescence Imaging in Lower Extremity Amputation Patients
This is a non-randomized prospective study of 30 patients scheduled to undergo lower extremity amputation (below the knee, through the knee or above the knee) evaluating bone perfusion and viability using indocyanine green (ICG)…
- Trial name
- NCT04250558
- Testing
- Lower Extremity Amputation
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Acute Pain, Fractures
Comparing Ketamine and Morphine in the Treatment of Acute Fracture Pain
Opioid pain medications such as morphine and dilaudid are commonly used in emergency departments to treat pain in patients. Physicians are familiar with the side effects of these medications; the most concerning of which is…
- Trial name
- NCT02430818
- Testing
- ketamine, morphine
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Urinary Retention, Hip Fractures
Onset PrevenTIon of Urinary Retention in Orthopaedic Nursing and Rehabilitation
Urinary retention (UR) is a common problem in older people undergoing hip surgery. Untreated UR can lead to bladder distention and a permanent damage of the bladder, which can cause both physical and psychical suffering as well…
- Conditions
- Urinary Retention, Hip Fractures, Hip Arthritis
- Trial name
- OPTION (NCT04700969)
- Testing
- : A support program to facilitate implementation of evidence-based practice for postoperative urinary retention
- Where
- 17 sites in Sweden
- Volunteers
- 20 people
- Sponsor
- Örebro University, Sweden
Femoral Fractures, Pelvic Fractures
Tactile Incentiviser Improves Partial Weight Bearing After Lower-Limb Surgery
Background: After lower-limb surgery, many patients are instructed to walk with only a fraction of their body weight on the operated leg (partial weight bearing).
- Conditions
- Femoral Fractures, Pelvic Fractures, Hip Fractures (ICD-10 72.01-72.2), Hip Arthroplasty
- Trial name
- NCT06989554
- Testing
- mechanical feedback insole, Standard physiotherapy without feedback device
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Università degli Studi dell'Insubria
Shoulder Osteoarthritis, Rotator Cuff Injuries
CBD for Pain Following Orthopedic Shoulder Surgery
The goal of the study is to learn if Epidiolex (cannabidiol) works as a additional pain medication in patients who have had orthopedic shoulder surgery.
- Trial name
- CBD (NCT06381791)
- Testing
- Epidiolex
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The Methodist Hospital Research Institute