Clinical trials: Orthopedic Procedure
Skeletal Class III Malocclusion
Efficacy of RME and Facemask Therapy for Class III Malocclusion
This multicenter randomized controlled trial compares the efficacy of Rapid Maxillary Expansion (RME) combined with facemask (FM) protraction versus FM protraction alone in treating growing children with skeletal Class III…
- Trial name
- NCT07053683
- Testing
- Combined RME and Facemask Therapy, Facemask Therapy Alone
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Wuhan Integrated Traditional Chinese and Western Medicine Hospital
Fascicular Block, Motor Activity
The Effects of Different Clonidine Concentrations on Axillary Brachial Plexus Block With 1,5% Lidocaine
The purpose of this study is to determine whether different clonidine concentration on axillary brachial plexus block with 1,5% lidocaine for upper limb surgery may influence the sensory and motor block onset time and duration…
- Conditions
- Fascicular Block, Motor Activity, Pain, Postoperative, Latency Period
- Trial name
- NCT01620112
- Testing
- high Clonidine concentration, low clonidine concentration, Lidocaine
- Volunteers
- 60 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Pain, Pain Management
Dose-Response Effects of a Brief Audio-Guided Mindfulness Intervention for Acute Pain
This project is a single-site, three-arm, randomized controlled trial investigating whether different length audio-recorded mindfulness practices differentially decrease pain among patients in a waiting room awaiting orthopedic…
- Conditions
- Pain, Pain Management, Mindfulness, Orthopedic
- Trial name
- NCT07562412
- Testing
- 1-Minute Mindfulness Intervention, 2-Minute Mindfulness Intervention, 3-Minute Mindfulness Intervention
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Florida State University
Preoperative Anxiety, Psychological Stress
Effect of Lavender Aromatherapy on Preoperative Anxiety, Stress, and Depression in Orthopedic Surgery Patients
This study evaluates whether inhalation aromatherapy with lavender essential oil can reduce anxiety, stress, and depression in adult patients before orthopedic surgery in Jordan.
- Conditions
- Preoperative Anxiety, Psychological Stress, Depressive Symptoms, Orthopedic Surgery Patients
- Trial name
- LAV-ORTHO (NCT07513831)
- Testing
- Lavender Essential Oil Inhalation
- Where
- Jordan
- Volunteers
- 128 people
- Sponsor
- Al-Zaytoonah University of Jordan
Hypovolemia, Hemorrhage
Trial of 6% HES130/0.4
The study shall evaluate the efficacy and safety of two different hydroxyethyl starch solutions (artificial colloids 6% HES130/0.4 and 6% HES70/0.5, Salinhes®) for intra-operative therapy of hypovolemia and maintenance of…
- Trial name
- NCT01010022
- Testing
- 6% hydroxyethyl starch 130/0.4, 6% hydroxyethyl starch 70/0.5 (Salinhes®)
- Where
- 7 sites in Japan
- Volunteers
- 64 people
- Sponsor
- Fresenius Kabi Japan
Dyspnea, Pulmonary Edema
The Incidence of TRALI in Patients Undergoing Orthopedic-Oncology Surgery
Currently Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related mortality in the United States, and one of major post-transfusion complications.
- Trial name
- NCT00914784
- Where
- Israel
- Volunteers
- 550 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Smoking Cessation, Fracture
Smoking Cessation Intervention in Acute Orthopedic Surgery
The purpose of this study was to evaluate if an intervention with smoking cessation starting during the acute hospitalization period and continuing during the acute postoperative phase of 6 weeks would reduce the frequency of…
- Trial name
- NCT00704015
- Testing
- Smoking cessation
- Volunteers
- 105 people
- Sponsor
- Karolinska Institutet
Fracture; Complication Orthopedic Procedure
The Effect of Using a Kaleidoscope on Fear and Pain in Children
The research was conducted in randomized controlled experimental type between May 2022 and December2023. The universe of the research consisted of children and their parents who were diagnosed with a fracture, applied to the…
- Trial name
- NCT06261112
- Testing
- kaleidescope
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mihriban Culha
Trigger Thumb
Study of Open and Percutaneous Release of Acquired Trigger Thumb
Trigger finger, also known as trigger digit or stenosing tenovaginitis, is caused by a size mismatch between the flexor tendon and the A1 pulley, which is generally characterized by pain, swelling, the limitation of finger range…
- Trial name
- NCT03679793
- Testing
- Open Release Group, Percutaneous Release Group
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Chronic Low Back Pain, Physiotherapy
Effect of Physiotherapeutic Interventions on Quality of Life in Patients With Chronic Low Back Pain. (Study 2)
The purpose of this study is to investigate the effect on QoL, PI and the AROM° in patients with non-specific chronic low back pain.
- Conditions
- Chronic Low Back Pain, Physiotherapy, Quality of Life, Range of Motion
- Trial name
- CLBP (NCT03309540)
- Testing
- Physioterapy intervention
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Orthopedic Disorder
Motor Imagery and Rehabilitation of Orthopaedic Patients
Motor imagery is increasingly used as a plasticity-booster to complement conventional rehabilitation. Here the investigators test the hypothesis that the combination of mental training with conventional rehabilitation may speed…
- Trial name
- NCT03370146
- Testing
- Mental training based on Motor Imagery, Cognitive training, Evaluation of gait abilities
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Osteoporotic Fracture
Effectiveness or Orthopedic Intervention in Osteoporosis Management After a Fracture of the Hip With Cost-Benefit Analysis
Patients who present with fragility fractures are consistently under-evaluated and under-treated for underlying osteoporosis. This point of care represents a lost opportunity to prevent future fractures.
- Trial name
- NCT02239523
- Testing
- Letter Group, Intervention Group
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Shaare Zedek Medical Center
Idiopathic Toe-walking
Efficacy of Surgery for Idiopathic Toe Walking
BACKGROUND: For children who walk on their tip toes, surgery is often done to lengthen their Achilles Tendon. However, there is little research to help children's surgeons choose which children with idiopathic toe walking should…
- Trial name
- FOREFOOT (NCT06610591)
- Testing
- Achilles Lengthening Surgery
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Oxford
Anxiety, Depression
Optimizing Mental Health in Orthopedic Care
This study will utilize qualitative cross-sectional and quantitative longitudinal methods. In semi-structured interviews, orthopedic providers and patients with spine conditions will discuss their overall perspectives, specific…
- Conditions
- Anxiety, Depression, Back Pain, Neck Pain
- Trial name
- NCT05194722
- Testing
- Wysa mobile app
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Orthopedic Procedures, Arthroplasty
Post Surgical Multimodal Analgesia With Oral Strong Opioids
This is a prospective observational case study, focusing on the clinical effectiveness of oral strong opioids for pain management following common orthopedic surgeries.The study aims to evaluate the effectiveness of multimodal…
- Conditions
- Orthopedic Procedures, Arthroplasty, Fracture Fixation
- Trial name
- ORORA (NCT06554457)
- Testing
- Multimodal analgesia with oral strong opioids
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Surgical Scar
The Management of Surgical Scars Around Knee After Pediatric Orthopedic Surgery: an Observational, Case-control Study
Scar is an unpleasant symptom that commonly appear after orthopedic surgery, especially the joint procedure. Due to the wide motion range, skin around joint has excessive tension that may increase risk for wide or conspicuous…
- Trial name
- NCT04928443
- Testing
- Scar dressing group, Regular care group
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Orthopedic Procedures, Obesity
Effect of BMI on Postoperative Morbidities of Orthopaedic Procedures
Obesity is associated with poor surgical outcome and complications. The literature does not provide a comprehensive view on the effect of body mass index (BMI) on perioperative outcomes in orthopedic surgeries.
- Trial name
- BMIORTHO (NCT04827888)
- Testing
- Orthopaedic surgery
- Where
- Lebanon
- Volunteers
- 76,189 people
- Sponsor
- American University of Beirut Medical Center
Interventional Radiology, Orthopedic Surgery
Change in Brain Perfusion During Induction of General Anesthesia
Arterial hypotension during general anesthesia remains a factor of poor outcomes, increases the risk of myocardial infarction, acute kidney injury and 1-year mortality.
- Trial name
- CERVO2 (NCT04288869)
- Testing
- Continuous monitoring of arterial blood pressure, Transcranial Doppler, Bispectral Index (BIS)
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Surgery
Study of Sutures Versus Staples for Skin Closure After Surgical Procedures of Hip
Skin closure either by sutures or staples is required after any surgical procedure of the hip. The purpose of this study is to compare the amount of drainage between patients who have had either staples or sutures placed for skin…
- Trial name
- NCT00273715
- Testing
- Surgical wound closure techniques, Surgical wound closure techniques (Comparator)
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- University of Kentucky
Anxiety, Satisfaction
The Effect of Virtual Tour Training Before Orthopedic Surgery
The purpose of the study is to determine the effect of training on surgical environments provided with virtual tour before orthopedic surgical ıntervention on patients' anxiety and satisfaction level.
- Trial name
- NCT06936540
- Testing
- Virtual Tour, No Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul University - Cerrahpasa