Clinical trials: Orthopedic Surgeries
Orthopedic Disorder, Anxiety
Brachial Plexus Block vs. General Anesthesia for Anesthesia Anxiety Before Orthopedic Upper Extremity Surgery
Surgical procedures and anesthesia applications are situations in which people do not feel safe due to the current vital risks. Anxiety is a natural reaction that occurs in such situations, it manifests itself with worry and…
- Conditions
- Orthopedic Disorder, Anxiety, Upper Extremity Injury, Surgery
- Trial name
- NCT05476198
- Testing
- Brachial plexus block, General anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Cryotherapy Effect, Compression
Combined Cryotherapy With Compression Versus Cryotherapy Alone After Orthopaedic Surgery
Cryotherapy has been used to enhance recovery after orthopaedic surgery. Many devices are available but few can guarantee a temperature regulation during a prolonged time and therefore have been criticized.
- Conditions
- Cryotherapy Effect, Compression, Postoperative Pain Management
- Trial name
- NCT05011084
- Testing
- Game Ready Cryotherapy with Compression Group, Control Cryotherapy Group
- Where
- United States
- Volunteers
- 348 people
- Sponsor
- Walter Reed National Military Medical Center
Anemia, Blood Transfusion
A Study of the Safety and Effectiveness of Epoetin Alfa in Facilitating Self-donation of Blood Before Surgery in Patients Who Are Undergoing Orthopedic Surgery and Who Have Low Hematocrit Levels (the Percent of Red Blood Cells in Whole Blood)
The purpose of this study is to evaluate the safety and effectiveness of epoetin alfa and to determine whether epoetin alfa will facilitate self-donation of blood before surgery in patients who have anemia, (as indicated by low…
- Conditions
- Anemia, Blood Transfusion, Orthopedic Procedures
- Trial name
- NCT00270114
- Testing
- epoetin alfa
- Volunteers
- 55 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Adjuvants, Anesthesia
Neostigmine Versus Dexamethasone as Adjuvants to Lidocaine During Intravenous Local Anesthesia
Intravenous regional anesthesia (IVRA) is described firstly in 1908 by August Bier. It is simple, safe, reliable, less cost, efficient method in forearm surgery.
- Trial name
- NCT03021772
- Testing
- Neostigmine, Dexamethasone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Anemia, Arthroplasty
Establishment of Optimal Transfusion Threshold After Major Orthopedic Surgery
The purpose of this study is to determine whether a higher threshold for transfusion with red blood cells improves the postoperative ambulation.
- Conditions
- Anemia, Arthroplasty, Replacement, Hip
- Trial name
- NCT00906295
- Testing
- Allowed drop in hemoglobin to 4.5-5.5 mmol/L, Allowed drop in hemoglobin to level between 5.6-6.5 mmol/L
- Where
- 2 sites in Denmark
- Volunteers
- 67 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lower Extremity Fracture
The Effect of Tele-Nursing Application on Self-Care Ability and Daily Living Activities in Fracture Surgery Patients
This study aims to determine the effect of tele-nursing application based on Orem's Self-care Theory on self-care agency and daily living activities in trauma-related lower extremity fracture surgery patients.
- Trial name
- NCT06284759
- Testing
- post-discharge telenursing intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Gazi University
Pediatric ALL, Nurse's Role
Applying Pediatric Nursing Excellence Model to Nurses in Orthopedic Surgery Care of Children
Problem description: Orthopedic surgeries are common in pediatric orthopedics, treating various conditions resulting from developmental, genetic, neoplastic, nutritional, infection, neurological, or physical injuries.
- Conditions
- Pediatric ALL, Nurse's Role, Surgery
- Trial name
- NCT06624007
- Testing
- pediatric Nursing Excellence (PNE) model
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Jouf University
Shivering, Postoperative Shivering
Optimizing the Paracetamol Dose for Prevention of Post-Spinal Shivering in Lower Limb Orthopedic Surgeries
Shivering is a common and distressing complication following spinal anesthesia, affecting up to 70% of patients. It significantly increases oxygen consumption, places stress on the cardiovascular system, and interferes with…
- Conditions
- Shivering, Postoperative Shivering, Hypothermia
- Trial name
- NCT07855575
- Testing
- Paracetamol 2 g, Paracetamol 1 g
- Volunteers
- 150 people
- Sponsor
- Assiut University
Hypotension
Dexamethasone Blunts the Hypotensive Effect of Spinal Anesthesia in Geriatric Patients Undergoing Lower Limb Orthopedic Surgeries
Based on the data that DEX increases the TPR and may decrease the expression of serotonin the investigator conducted this study to test the hypothesis that the prophylactic intravenous infusion (IVI) of DEX can attenuate the…
- Trial name
- NCT03664037
- Testing
- Dexamethasone phosphate
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Metabolomics, Anesthesia, General
Metabolic and Physiological Changes During Minor Orthopaedic Surgery in Otherwise Healthy Patients
The air we breathe contains 21% of oxygen. Oxygen is vital for the cells ability to produce energy and without it we could not survive. Oxygen normally exists as a molecule consisting of two atoms, O2.
- Conditions
- Metabolomics, Anesthesia, General, Oxygen
- Trial name
- NCT03450746
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Muscle Atrophy, Postoperative Pain
Post-surgery Muscle Preservation and Pain Reduction Through Blood Flow Restriction Training in Orthopedic Spinal Surgery
This project investigates the effects of the Blood-Flow-Restriction (BFR) training method on postoperative muscle atrophy and pain after spinal surgery. Two groups are formed for this purpose.
- Conditions
- Muscle Atrophy, Postoperative Pain, Spondylolisthesis, Spondylodiskitis
- Trial name
- NCT06962683
- Testing
- Blood-Flow-Restriction Training
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bonn
Hand Surgery, Orthopedic Surgery
Evaluating Clinical Outcomes for Determining the Optimal Delay to Skin Incision Under WALANT
Further studies are needed to establish the effects of WALANT in performing most common hand surgeries, in relation to its clinical outcomes and intraoperative blood loss.
- Trial name
- WALANT (NCT04491656)
- Testing
- WALANT Technique
- Where
- Philippines
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- East Avenue Medical Center, Philippines
Aortic Diseases, Osteoarthritis, Hip
Pro-inflammatory Cytokines in Blood From Orthopedic Surgery Compared to Abdominal Aneurysm Repair
The purpose of this study is to investigate the contents in blood sampled from surgery site during hip replacement compared with blood sampled from abdominal aortic surgery.
- Trial name
- KEEP-HB (NCT00851149)
- Testing
- Sangvia blood sampling system
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Sykehuset i Vestfold HF
Cerebral Palsy (CP)
Does Orthopedic Surgery Improve Gait Efficiency in Children With Cerebral Palsy? A Retrospective Study
Purpose: The aim of this retrospective observational study is to describe the demographic, clinical, and functional characteristics of children and adolescents with spastic cerebral palsy (CP) undergoing Single Event Multilevel…
- Trial name
- OrthoSurg01 (NCT06624280)
- Testing
- single-event multilevel surgery
- Where
- 2 sites in Italy
- Volunteers
- 78 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Arthroplasty Replacement, Knee, Arthroplasty Total Hip Replacement
A Prospective, Single-arm, Trial to Determine Contamination Rates When Using an Antibacterial Incise Drape During Orthopedic Surgery
The goal of this clinical study is to generate data on the intended use of a chlorhexidine gluconate (CHG)-impregnated antimicrobial incise drape.
- Trial name
- NCT07356323
- Testing
- 3M™ Ioban™ CHG Chlorhexidine Gluconate Incise Drape (2% w/w CHG)
- Where
- 2 sites in United States
- Volunteers
- 179 people
- Sponsor
- Solventum US LLC
PJI, Spondylodiscitis
Paper-based Electrochemical Point-of-care Device in Diagnostic of Orthopedic Infections
Periprosthetic Joint infections (PJI) and spondylodiscitis are considered some of the most costly infectious diseases because require at least one surgery, prolonged hospitalisation, rehabilitation care, prolonged antibiotherapy…
- Trial name
- Ortho-PoC (NCT06666023)
- Testing
- Device
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Surgery
Load Limits After Orthopaedic Surgery: Biofeedback vs. Conventional Method (AppPWB)
The aim of this single-centre prospective randomized-controlled clinical trial is to assess whether patients adhere to prescribed weight bearing limits after surgical orthopaedic or traumatological interventions more accurately…
- Trial name
- NCT06426576
- Testing
- Standard one-off instruction using a scale, Plantar pressure insoles
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University Hospital, Basel, Switzerland
Delirium, Postoperative Delirium
Stanford PIPRA Validation Study in an Elderly Orthopedic Population
The purpose of this study is to determine the accuracy of an AI-based tool in the prediction of postoperative delirium (POD), in a population at moderately high risk of developing this syndrome (i.e., elderly orthopedic…
- Conditions
- Delirium, Postoperative Delirium, Cognitive Impairment
- Trial name
- PIPRA-ORTHO (NCT06567574)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Stanford University
Anesthesia, Spinal
Caval-aorta Index and Perfusion Index on Predict Hypotension After Spinal Anaesthesia in Elderly
The aim of our study was to predict hypotension by using caval aorta index and perfusion index in elderly patients who may develop hypotension after spinal anesthesia.
- Trial name
- NCT06479512
- Testing
- ultrasonography to measure the index of the caval aorta and non-invasive pulse oximetry for perfusion index
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Achilles Tendon Rupture, Database
Barriers to Efficient PACU Discharge at a Major Academic Orthopaedic Ambulatory Surgery Center
This is a retrospective chart review to determine the etiologies contributing to prolonged PACU discharge at a major Orthopedic Ambulatory Center
- Trial name
- NCT04356612
- Testing
- Chart Review
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York