Clinical trials: Orthopedic Surgeries
Acute Postoperative Pain, Motor Activity
Axillary Brachial Plexus Block Using 0.25% Bupivacaine Versus Using 0.19%Bupivacaine in Pediatrics
Postoperative pain is a common manifestation in orthopedic patients, mainly due to intraoperative tissue damage and inadequate intraoperative pain assessment and management .Axillary brachial plexus block provides motor and…
- Trial name
- NCT05386095
- Testing
- 0.25%Bupivacaine Axillary brachial plexus block, 0.19% Bupivacaine Axillary brachial plexus block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Orthopedic Surgery, Nursing Care
Effect of Earplugs and Eye Masks Used After Orthopedic Surgery on Comfort and Quality of Recovery
This research will be conducted as a randomized controlled trial to determine the effects of earplugs and eye masks used after orthopedic surgery on comfort and quality of recovery.
- Conditions
- Orthopedic Surgery, Nursing Care, Quality of Recovery 40, Comfort
- Trial name
- NCT06986408
- Testing
- Earplugs and Eye Masks
- Volunteers
- 60 people
- Sponsor
- Ankara Yildirim Beyazıt University
Knee Replacement, Musculoskeletal
Intelligent Operating Room (InOR) for Orthopaedic Surgery
The objective of the study is to evaluate the usefulness of digital technologies to support surgical teams before, during, and after an operation.
- Trial name
- InOR (NCT04167787)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Digital Surgery Ltd.
Ankle Fracture
Liposomal Bupivacaine With Bupivacaine in Ankle Fracture Open Reduction Internal Fixation (ORIF)
This study is a randomized controlled trial assessing pain control in ankle fractures repaired with open reduction and internal fixation.
- Trial name
- NCT02480621
- Testing
- Liposomal Bupivacaine with Bupivacaine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Jamaica Hospital Medical Center
Lower Limb Surgery
Spinal Anaesthesia With Levobupivacaine 0.5% and Ropivacaine 0.75% for Lower Limb Orthopaedic Surgery
The purpose of this study is to compare the effects of two intrathecally administered drugs:0.5% levobupivacaine and0.75%Ropivacaine in spinal anesthesia
- Trial name
- NCT02201784
- Testing
- Levobupivacaine, Ropivacaine
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Aligarh Muslim University
Cerebral Palsy, Muscle
How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery.
Cerebral palsy (CP) is a motor disorder caused by an injury to the immature brain. Even though the brain damage does not change, children with CP will have progressively weaker, shorter and stiffer muscles that will lead to…
- Conditions
- Cerebral Palsy, Muscle, Muscle Contracture, Muscle Spasticity
- Trial name
- CPTDBiopsy (NCT05506228)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eva Ponten
Deep Vein Thrombosis, Venous Thrombosis
Echo-Doppler Assessment of the Occurrence of Asymptomatic DVT in Orthopedic Replacement Surgery Under Enoxaparin
The objectives of the study are: o Objective ultrasound: Determine the presence or absence of subclinical DVT in practicing ultrasound-Doppler Day7 and Day35, patients who underwent TKA or THA o Clinical objective To evaluate the…
- Conditions
- Deep Vein Thrombosis, Venous Thrombosis, Adverse Effect of Anticoagulants
- Trial name
- PRENOXA (NCT01354704)
- Testing
- Enoxaparin
- Where
- Tunisia
- Volunteers
- 153 people
- Sponsor
- Les Laboratoires des Médicaments Stériles
Surgery
Study of Sutures Versus Staples for Skin Closure After Surgical Procedures of Hip
Skin closure either by sutures or staples is required after any surgical procedure of the hip. The purpose of this study is to compare the amount of drainage between patients who have had either staples or sutures placed for skin…
- Trial name
- NCT00273715
- Testing
- Surgical wound closure techniques, Surgical wound closure techniques (Comparator)
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- University of Kentucky
Anesthesia
Effect of Acupoint Electrical Stimulation on Incidence of Hypotension After Spinal Anesthesia
This study is intended to include elderly patients who are selected to undergo lower limb and pelvic orthopedic surgery under spinal anesthesia.
- Trial name
- NCT05716399
- Testing
- Transcutaneous electric stimulation pretreatment, Transcutaneous acupoint electrical stimulation treatment, Transcutaneous acupoint pseudo electric stimulation
- Volunteers
- 111 people
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Occlusive Dressings, Nursing
Wich is the Best Dressing in Wounds by Primary Surgery of THA and / or TKA?
Surgical wounds are covered to prevent bleeding, absorb the exudates and provide a barrier against external contamination. Currently, in Corporació PT after orthopedic surgery, traditional occlusive dressing of sterile gauze and…
- Conditions
- Occlusive Dressings, Nursing, Knee Surgery, Hip Surgery
- Trial name
- NCT03190447
- Testing
- Aquacel Surgical®, Mepilex Border post-op®, Opsite post-op visible®
- Where
- Spain
- Volunteers
- 560 people
- Sponsor
- Corporacion Parc Tauli
Ischemia Limb, Blood Circulation Disorder
Ischemia Detection During Development of Acute Compartment Syndrome
This is an open, observational, prospective, descriptive, single-centre study including 60 patients. The study is designed to investigate if IscAlert sensor system can be used for reliable and continuous tissue carbon dioxide…
- Conditions
- Ischemia Limb, Blood Circulation Disorder, Carbon Dioxide, Biosensing Techniques
- Trial name
- IDEA (NCT06079255)
- Testing
- IscAlert sensor(s) in patient with risk of acute compartment syndrome
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Anterior Cruciate Ligament Injury, Knee Injury
Comparison of Quadriceps and Semitendinosus Grafts in ACL Reconstruction Using Data From the Danish Knee Ligament Reconstruction Registry (DKRR)
This study looks at two different types of tendon (tissue) used in knee surgery to repair a torn anterior cruciate ligament (ACL), which is a common injury in active people.
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injury, Ligament Reconstruction, Sports Injuries
- Trial name
- NCT06980285
- Where
- Denmark
- Volunteers
- 2,500 people
- Sponsor
- Abdirahman Hassan Omar
Hypoxemia During Surgery, Atelectasis
Usage of High Flow Nasal Cannula in Preventing Desaturations in Elderly Patients Going for Lower Limb Surgeries
To study the effect of high flow nasal cannula in comparisons with nasoprong used intraoperatively in patients oxygenation status
- Trial name
- NCT06054022
- Testing
- high flow nasal cannula, nasoprong oxyen 2Litres per minute
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Constipation, Orthopedic Disorder
Effect of Pre-Surgery Constipation Podcast: A RCT
In this study, the investigators will evaluate the effect of a podcast on constipation on the number of patients with constipation.
- Trial name
- NCT06877078
- Testing
- Constipation information via Podcast
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Central Jutland Regional Hospital
Tranexamic Acid, Knee Osteoarthritis
Tranexamic Acid in Major Orthopedic Surgery: Comparison of 3 Dosage Regimen
Tranexamic acid has been shown to be effective in reducing blood loss and transfusion in orthopedic surgery. It remains unknown the ideal therapeutic regimen.
- Conditions
- Tranexamic Acid, Knee Osteoarthritis, Ankle Osteoarthritis, Bleeding
- Trial name
- NCT03573245
- Testing
- Tranexamic Acid
- Volunteers
- 210 people
- Sponsor
- CUF Santarém Hospital
Procedural Sedation, Regional Anesthesia Block
Lusedra (Fospropofol Disodium) for Minimal to Moderate Sedation for Regional Anesthesia Block Prior to Orthopedic Surgery
How does Lusedra compare with current standard of care (midazolam) for minimal to moderate sedation for regional anesthesia blocks prior to orthopedic surgery?
- Conditions
- Procedural Sedation, Regional Anesthesia Block, Orthopedic Surgery
- Trial name
- NCT01195103
- Testing
- Fospropofol disodium, Fentanyl
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Mayo Clinic
Osteoarthritis, Knee
Pathogen Screening in OA Orthopaedic Surgical Patients
The purpose of this study is to screen orthopedic surgery patients with and without a diagnosis of osteoarthritis for the presence of 11 pathogens associated with periodontal disease (PD) from a collection of oral rinse, synovial…
- Trial name
- NCT03394170
- Testing
- Collection of specimens prior to and during surgery
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Stone Research Foundation for Sports Medicine and Arthritis
Infection Prosthesis Hip and Knee, Infection, Prosthesis Related
Results of Extended Versus Single Dose Antibiotic Prophylaxis In Orthopedic Revision Arthroplasty in Nijmegen.
The goal of this randomized control trial is to investigate the superiority of 5 days (extended) versus a single dose of cefazolin prophylaxis in revision arthroplasty of the hip and knee.
- Conditions
- Infection Prosthesis Hip and Knee, Infection, Prosthesis Related, Joint Infection, Infection, Surgical Site
- Trial name
- REViSION (NCT06402591)
- Testing
- Cefazolin
- Where
- Netherlands
- Volunteers
- 751 people
- Sponsor
- Radboud University Medical Center
Surgery, Anterior Shoulder Instability
The Effects of Different Surgical Stabilization Methods in Recurrent Anterior Shoulder Instability
Shoulder instability is the inability to retain the humeral head in the glenoid fossa. The incidence of instability is 8.2 to 23.9 per 100,000 person-years with an estimated prevalence of 1.7%.
- Trial name
- SSM-SI (NCT06154460)
- Testing
- Laterjet Surgery, Reimplissage Surgery, Capsular Reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Orthopaedic Disorders
Experience of Orthopaedic and Spine Center Pakistan During COVID-19
After the frightful outbreak in the city of Wuhan, China and its evidence of being contagious, governments around the world particularly United States in an effort to stop the transmission- imposed travel restrictions to and from…
- Trial name
- NCT04516824
- Testing
- Orthopaedic Surgical Procedures
- Where
- Pakistan
- Volunteers
- 2,160 people
- Sponsor
- Ghurki Trust and Teaching Hospital