Clinical trials: Orthopedic Surgeries
Postoperative Pain
Determination of the Effective Dose of a Single Intravenous Dose of Tegileridine Fumarate for Postoperative Analgesia After Orthopedic Surgery: A Up-and-Down Sequential Allocation Study
The goal of this clinical trial is to determine the 90% effective dose (ED90) of a single intravenous injection of tegileridine fumarate for postoperative analgesia in adult patients aged 18-75 years with American Society of…
- Trial name
- NCT07353996
- Testing
- Single intravenous injection of Tegileridine Fumarate
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Metastatic Cancer to the Hip
Fully Constrained Acetabular Liner vs. Dual Mobility Hip Joint in the Surgical Treatment of Metastatic Bone Disease of the Hip
The purpose of the current study is to investigate whether dual mobility liners are non-inferior til constrained liners regarding the post-operative hip joint dislocation risk following total hip replacement in patients with…
- Trial name
- NCT05461313
- Testing
- Constrained Liner, Dual Mobility
- Where
- Denmark
- Volunteers
- 146 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hyperglycemia
Glycemic Instability After Spine Surgery
Analyzing peri operative changes in blood glucose levels from non-diabetic patients undergoing spine surgery
- Trial name
- GLYRACH (NCT01975883)
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Beaujon Hospital
Postoperative Pain, Upper Extremity Fracture
Ropivacaine Alone Versus Ropivacaine Plus Lidocaine With or Without Epinephrine for Supraclavicular Brachial Plexus Block in Upper Limb Orthopedic Surgery
This randomized controlled trial compared three local anesthetic solutions for ultrasound-guided supraclavicular brachial plexus block in adults aged 18 to 59 years undergoing upper limb orthopedic and trauma surgery at a general…
- Conditions
- Postoperative Pain, Upper Extremity Fracture, Anesthesia, Conduction
- Trial name
- NCT07907666
- Testing
- ropivacaine, lidocaine, lidocaine with epinephrine
- Where
- Mexico
- Volunteers
- 138 people
- Sponsor
- Instituto Mexicano del Seguro Social
All
Patient Satisfaction in the Orthopedic Surgery Clinic
Patients in the orthopedic surgery clinic routinely fill out a patient- reported outcome measurement survey prior to their visit.
- Trial name
- NCT04343027
- Testing
- Review
- Sponsor
- NYU Langone Health
Arthroplasty, Replacement, Shoulder, Shoulder Osteoarthritis
Does BIO-RSA Provides Superior Clinical Outcome Compared to Conventional RSA?
The goal of this clinical trial is to compare two different types of reverse shoulder replacements. Researchers will compare a conventional reverse shoulder replacement with a lateralized reverse shoulder replacement to see if…
- Trial name
- CARS-1 (NCT06025331)
- Testing
- BIO-RSA, RSA
- Where
- 2 sites in Norway
- Volunteers
- 130 people
- Sponsor
- Lovisenberg Diakonale Hospital
Soft Tissue Injuries
"Enhancing Surgical Safety in Developing Nations: Investigating Antibiotics' Role in Hand Surgeries."
The goal of this clinical trial is to compare the use of antibiotics with no use in people undergoing soft tissue hand surgery in developing countries.
- Trial name
- NCT05990842
- Testing
- Antibiotic
- Volunteers
- 51 people
- Sponsor
- Marcos Felipe Marcatto de Abreu
Hip Arthrosis, Osteoarthritis
Capsulectomy vs Capsulotomy With Repair in Direct Anterior Total Hip Arthroplasty
In this prospective, randomized study, investigators will look at the outcome of total hip arthroplasty through the anterior approach in regard to the surgical treatment of the anterior hip capsule.
- Conditions
- Hip Arthrosis, Osteoarthritis, Arthritis
- Trial name
- NCT02121964
- Testing
- Capsulectomy in Direct Anterior Total Hip Arthroplasty, Capsulotomy in Direct Anterior Total Hip Arthroplasty
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Emory University
Spinal Anesthesia Duration
Comparative Analysis of Intraoperative Effect Dexmedetomidine and Fentanyl as an Adjuvant to Heavy Bupivacaine in Spinal Anaesthesia in Lower Limb Orthopedic Surgeries to Evaluate the Hemodynamic Stability and Onset and Duration of Motor Block of Using Intrathecal Dexmedetomidine and Fentanyl
Spinal anesthesia is the most widely employed procedure for lower limb orthopedic operations, as it is very cost-effective and simple to apply.
- Trial name
- NCT07078201
- Testing
- Dexmedetomidine, fentanyl
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Nashwa Ahmed
Anesthesia
Efficacy of Virtual Reality Distraction Technique for Anxiety and Pain Control in Orthopedic Forearm Surgeries Performed Under Supraclavicular Brachial Plexus Block
Invistigators hypothesized that using of VR distraction technique during performing peripheral regional anesthesia (supraclavicular block) would lead to better perioperative analgesia and less anxiety.
- Trial name
- NCT05512728
- Testing
- VR, Midazolam
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Orthopedic Disorder, Thoracic
Epidemiological Data on Pain
The ALGOBASES project is an observational epidemiological study of pain through the collection of pain evaluation questionnaires and information with the aim of creating a descriptive "pain" evaluation in all patients who need to…
- Conditions
- Orthopedic Disorder, Thoracic, Gynecological; Surgery (Previous), Causing Obstructed Labor, Affecting Fetus, Pain
- Trial name
- ALGOBASES (NCT04546594)
- Sponsor
- University Hospital, Lille
Anesthesiology, Pediatrics
A Prospective Study to Bilaterally Compare a Non-Invasive Cardiac Output Monitor
Study hypothesis: The Cardiotronic ICON non-invasive cardiac output monitor gives accurate information when placed on a patient's Right or Left side.
- Conditions
- Anesthesiology, Pediatrics, General Surgery, Orthopedics
- Trial name
- NCT01678066
- Testing
- Bilateral cardiac output
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis (AIS) Gold Standard for Blood Loss
The purpose of this study is to establish a benchmark for measuring blood loss by directly measuring the change in red cell volume before and after surgery and to compare established blood loss estimators to this benchmark in…
- Trial name
- NCT03990376
- Testing
- Radioisotope I-131-labeled albumin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Regional Anesthesia, Music
MUSIC-CARE and Locoregional Anesthesia for Orthopedic Surgery
Anxiety, fright, stress and pain have always been sources of emotional distress for patients undergoing invasive procedures in clinical settings.
- Conditions
- Regional Anesthesia, Music, Forearm; Injury, Superficial, Multiple (With Elbow)
- Trial name
- NCT05015985
- Testing
- Music-Care, control group
- Where
- France
- Volunteers
- 80 people
- Sponsor
- American Hospital of Paris
Venous Thromboembolism
Evaluation of AVE5026 as Compared to Placebo for the Extended Prophylaxis of Venous Thromboembolism in Patients Having Undergone Hip Fracture Surgery
The primary objective is to evaluate the efficacy of once daily (QD) subcutaneous (SC) injections of Semuloparin sodium (AVE5026) versus placebo for 3 additional weeks following an initial 7 to 10-day venous thromboprophylaxis…
- Trial name
- SAVE-HIP3 (NCT00709904)
- Testing
- Open-label Semuloparin sodium, Semuloparin sodium
- Where
- 16 sites in United States, Belarus and 14 more
- Volunteers
- 469 people
- Sponsor
- Sanofi
Patients Undergoing Orthopedic Hip Surgery Under Spinal Anesthesia, Orthopedic Hip Sugery in Eldely Patients
Comparison of Norepinehrine Versus Phenylepherine Infusion for Prevention of Post-spinal Hypotension
This prospective randomized double-blinded clinical trial aims to compare the efficacy and hemodynamic effects of prophylactic norepinephrine infusion versus phenylephrine infusion for prevention of spinal anesthesia-induced…
- Trial name
- NCT07662408
- Testing
- Norepinephrine, Phenylephrine
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sohag University
Orthopedic Disorders, Surgical Site Infection
Preoperative Decolonization and Surgical Site Infections - a Prospective Randomized Trial
Surgical site infections are a major postoperative complication and are mostly due to colonization with endogenous germs, like Staphylococcus aureus, Staphylococcus epidermidis or Propionibacterium acnes.
- Trial name
- DECO-SSI (NCT02560155)
- Testing
- Mupirocin 2% nasal ointement, Chlorhexidine sol 4%
- Where
- Switzerland
- Volunteers
- 1,300 people
- Sponsor
- Lindenhofgruppe AG
Orthopedic Disorder, Post Operative Pain
Nonpharmacological Management of Postoperative Pain in Children
The 3 non-pharmacological methods of online gaming, cold application, and placebo were chosen to reduce postoperative pain in children undergoing orthopedic and traumatology surgery.
- Trial name
- NCT05893680
- Testing
- Group to play online games, Group that received cold application, Group that played an online game and received cold application at the same time
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- İlke Karabıyık
Distal Radius Fracture, Distal Radius Fracture Fixation
Evaluating the Effectiveness of Remote Monitoring for Post-Operative Management of Distal Radius Fractures
This randomized controlled trial evaluates whether remote monitoring can provide a safe and effective alternative to traditional in-person follow-up after surgical fixation of distal radius fractures.
- Trial name
- NCT07219979
- Testing
- Remote Monitoring Follow-Up, Standard In-Person Follow-Up
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Missouri-Columbia
Knee Arthroplasty, Total
BLOCK-study: Better Local Orthopedic Pain Control After Knee Arthroplasty
The goal of this study is to compare the anesthetic combination iPACK with femoral triangle block versus surgical LIA for unilateral TKA.
- Trial name
- BLOCK (NCT06746168)
- Testing
- Locoregional anesthesia, Local Anesthetic Ropivacaine
- Where
- Belgium
- Volunteers
- 210 people
- Sponsor
- Jessa Hospital