Clinical trials: Orthopedic Surgeries
Postoperative Pain
Intrathecal Dexmedetomidine vs Midazolame
Prospective Randomized Controlled Clinical Trial to Compare Intrathecal Dexmedetomidine Versus Midazolame in Orthopedic Cancer Surgeries
- Trial name
- NCT06315634
- Testing
- Dexmedetomidine, Midazolam, Bupivacain
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Shoulder, Orthopedic Surgery
Ultrasound Guidance for Interscalene Brachial Plexus Block
This study has been designed to assess the possible advantages of using ultrasound imaging to block the brachial plexus (i.e., nerves of the upper limb) in patients undergoing shoulder surgery.
- Conditions
- Shoulder, Orthopedic Surgery, Nerve Block
- Trial name
- NCT00702416
- Testing
- Ultrasound-guided continuous interscalene brachial plexus block, Continuous interscalene brachial plexus block using electrical nerve stimulation, Ropivacaine
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Parma
Total Hip or Knee Arthroplasty
Transfusion Requirements in Orthopedic Surgery (PHASE 2)
The objective of our research program is to determine the transfusion threshold required to maximize functional recovery after major orthopedic surgery (total hip/knee replacement) in these, most often, elderly patient with…
- Trial name
- TRIOS (NCT00726349)
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 305 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Patella Fracture, Surgery
Tension Band Versus Locking Plate Fixation for the Treatment of Patella Fractures
This study is a multicenter pragmatic, prospective, assessor-blinded, randomized independent clinical trial in which we compare locking plate fixation to standard tension band fixation in patients with patella fractures.
- Conditions
- Patella Fracture, Surgery, Orthopedic Disorder
- Trial name
- TENPLA (NCT04891549)
- Testing
- Tension band fixation, Plate fixation
- Where
- 6 sites in Denmark
- Volunteers
- 122 people
- Sponsor
- Rasmus Elsøe
Arthroplasty Complications, Shoulder Osteoarthritis
Is MIO-RSA Noninferior to BIO-RSA When it Comes to Mechanical Implant Stability?
This clinical trial will investigate whether metallic lateralization in reverse shoulder arthroplasty is as stable as bony lateralization during the first two postsurgical years, measured with CT-based motion analysis (CTMA).
- Trial name
- CARS-2 (NCT06025448)
- Testing
- BIO-RSA, MIO-RSA
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Lovisenberg Diakonale Hospital
Anesthesia, Dexmedetomidine
IV Dexmedetomidine in the Duration of Spinal Anesthesia With Hyperbaric Bupivacaine: Double Blind Randomized Trial.
Introduction: Spinal anesthesia produces sensitive and motor block according to the administered local anesthetic. The total duration of surgical anesthesia depends on the dose, intrinsic properties of the anesthetic, and the use…
- Trial name
- NCT05335655
- Testing
- Dexmedetomidine injection, Sodium Chloride 0.9% infusion
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Central "Dr. Ignacio Morones Prieto"
Older Adults, Anxiety
Behavioral Activation and Medication Optimization for Perioperative Mental Health Feasibility Study
Inadequate management of preoperative mental health disorders often contributes to poor postoperative outcomes, including increased rates of readmission, delirium, falls, and mortality.
- Conditions
- Older Adults, Anxiety, Depression, Cardiac Surgery
- Trial name
- NCT05110690
- Testing
- Behavioral Activation, Medication Optimization
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Washington University School of Medicine
Distal Radius Fractures, Rehabilitation
Evaluation of Limb Function and Perception in Rehabilitation After Traumatic Wrist Fracture Surgery
The goal of this observational study is to assess the functional and perceptual alterations of the affected limb during rehabilitation in adult orthopedic patients who underwent surgical treatment for distal radius fractures.
- Conditions
- Distal Radius Fractures, Rehabilitation, Body Perception
- Trial name
- NCT06866340
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Femoral Neck Fractures
MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)
This study is an intervention domain of the Musculoskeletal Adaptive Platform Trial. The primary goal of this pragmatic, randomized, open-label, comparative effectiveness trial is to evaluate if arthroplasty is superior to…
- Trial name
- FASTER-HIP (NCT07244211)
- Testing
- Hip arthroplasty, Internal fixation
- Where
- 31 sites in United States, Canada and 3 more
- Volunteers
- 600 people
- Sponsor
- University of Southern California
Orthopedic Disorder
Opioid Counseling Following Orthopaedic Surgery
Postoperative pain management and opioid consumption following outpatient orthopaedic surgery may be influenced by a number of variables including knowledge of safe opioid use.
- Trial name
- NCT04138264
- Testing
- Preoperative opioid counseling
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- Rothman Institute Orthopaedics
Lower Extremity Surgery, Upper Extremity Surgery
Perineural Catheter Insertion Distance for Continuous Peripheral Nerve Blocks
This is a research study to determine if the effects of continuous peripheral nerve blocks are influenced by the distance of insertion past the needle tip of the perineural catheter.
- Conditions
- Lower Extremity Surgery, Upper Extremity Surgery, Post-operative Pain
- Trial name
- NCT00997867
- Testing
- Sciatic catheter left 0-1cm past needle tip vs. 5-6cm past needle tip
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of California, San Diego
Pediatric ALL, Nurse's Role
Applying Pediatric Nursing Excellence Model to Nurses in Orthopedic Surgery Care of Children
Problem description: Orthopedic surgeries are common in pediatric orthopedics, treating various conditions resulting from developmental, genetic, neoplastic, nutritional, infection, neurological, or physical injuries.
- Conditions
- Pediatric ALL, Nurse's Role, Surgery
- Trial name
- NCT06624007
- Testing
- pediatric Nursing Excellence (PNE) model
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Jouf University
Orthopedic Disorder, Metabolism and Nutrition Disorder
NUtrition and ORal Health in Orthopaedic Surgery
This prospective observational study evaluates the relationship between the objective oral health status and the patient reported diet in 64 adult patients undergoing elective major orthopaedic surgery (hip, knee, or spine…
- Trial name
- NCT06327854
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Chronic Pain
Predisposition to Persistent Pain After Orthopaedic Surgery: Genetic Aspects
The study purpose is to examine polymorphism of genes associated to post-operative persistent pain and to verify the possible association between genotype phenotype and ADRB2 polymorphism in orthopaedic surgery.
- Trial name
- NCT01989351
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- ASST Gaetano Pini-CTO
Medication Disposal, Behavior
Excess Opioid Disposal Following Orthopedic Foot and Ankle Surgery
This study aims to survey the drug disposal methods of orthopedic foot and ankle patients with excess pain medication following and operation.
- Trial name
- NCT03285061
- Testing
- Deterra Drug Deactivation System
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Delirium
Influence of Apelin Levels on Postoperative Cognitive Disorders After Orthopedic Surgery in Elderlies (APOCOGNIT)
No successful strategy is proposed to patients submitted to important surgery to reduce the incidence of postoperative cognitive disorders (POCD) onset.
- Trial name
- APOCOGNIT (NCT02574234)
- Testing
- Determination of apelin and inflammatory cytokines, Assessment of cognitive functions, Liquid sampling cerebrospinal
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Toulouse
Iron Deficiency Anemia
Intravenous Ferric Carboxymaltose (Ferinject®) With or Without Erythropoietin in Patients Undergoing Orthopaedic Surgery
Study Design: Single-centre, block randomised, blinded, controlled, phase IIIb, parallel group pilot study. Primary Objective: To evaluate the effect of the administration of ferric carboxymaltose (Ferinject®) with or without…
- Trial name
- NCT00706667
- Testing
- Ferinject ®
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- University of Zurich
Fracture of Distal End of Radius
Evaluation of an Innovative Medical Device Supporting Orthopedic Surgical Interventions
This study is a randomized, controlled, 2-arm, open trial to evaluate an innovative positioning system in the clinical setting of orthopedic surgery.
- Trial name
- VIPS (NCT01670344)
- Testing
- Treatment with investigational method (virtual implant positioning system), Treatment with surgical standard of care
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Siemens Healthcare QT
Quality of Recovery (QoR-15), Quality of Recovery From Anaesthesia
Validation of the Setswana Translated Quality of Recovery Questionnaire in Orthopaedic Patients at a Tertiary Hospital in South Africa
This observational study aims to evaluate the validity, reliability and feasibility of the Setswana-translated version of the 15-item Quality of Recovery (QoR-15) questionnaire.
- Trial name
- NCT07194369
- Where
- South Africa
- Volunteers
- 150 people
- Sponsor
- Sefako Makgatho Health Sciences University
Tendon Disorder
A Musculoskeletal Ultrasound Course for Orthopedic Surgery Residents
A group of orthopedic surgery residents underwent a structured online and practical musculoskeletal ultrasound course. Their proficiency on a written and practical exam, as well as frequency and comfort when using was recorded…
- Trial name
- NCT04204369
- Testing
- Ultrasound education curriculum
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke