Clinical trials: Orthopedic Surgeries
Knee Arthropathy, Hip Injuries
A Study to Evaluate Virtual Reality As Adjunct to Anesthesia During Orthopedic Surgery
The purpose of this study is to obtain feedback from patients and orthopedic surgeons who agree to use virtual reality (VR ) as an adjunct to standard of care in orthopedic cases under regional or central neuraxial nerve block.
- Trial name
- NCT05112302
- Testing
- Virtual reality
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Analgesia
Evaluation of Perineural Catheterization Practices in Postoperative Orthopedic Surgery
Continuous peripheral nerve blocks are considered as the gold standard for postoperative analgesia in orthopaedic surgery (shoulder, knee, foot). These techniques are also used in chronic pain.
- Trial name
- Cathepos (NCT04011839)
- Testing
- Levobupivacaïne
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Cannabis, Marijuana
Analgesic Consumption in Chronic Marijuana Users Following Orthopedic Trauma Surgery
Marijuana use has increased since its legalization in Canada and many believe that it may help patients that are experiencing chronic pain.
- Trial name
- NCT04587700
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of Alberta
Orthopedic Surgery
Dynamic Multimodal Monitoring for Ultrasound Guided Peripheral Nerve Blockade
In clinical practice, local anesthetic injection pressure monitoring is performed manually or by a pressure transducer according to the availability of the equipment or preferences of clinicians.
- Trial name
- NCT02737137
- Testing
- Manual measurement, Measurement with a gauge
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Montpellier
Postoperative Urinary Retention
The Effect of Hot-Cold Application to the Bladder After Orthopedic Surgery on Postoperative Urinary Retention
The development of postoperative urinary retention (PUR) is a significant complication in patients undergoing treatment due to orthopedic surgery.
- Trial name
- PUR (NCT05969145)
- Testing
- application of thermophor
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Orthopedic Surgery
Intraoperative Methadone for the Prevention of Postoperative Pain
The pain felt after orthopedic surgery in the absence of adequate locoregional anesthesia is often insufficiently controlled, especially during the first 24 hours postoperatively.
- Trial name
- NCT05831345
- Testing
- Methadone Hydrochloride, Sufentanil Citrate
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Brugmann University Hospital
Anemia, Blood Transfusion
A Study to Determine an Effective Dose of Epoetin Alfa to Decrease the Number of Units of Blood Required to be Transfused During Hip Replacement Surgery.
The purpose of this study is to determine an effective dose of epoetin alfa to be administered prior to surgery, to decrease the need for blood transfusions during hip replacement.
- Conditions
- Anemia, Blood Transfusion, Orthopedic Surgery
- Trial name
- NCT00269971
- Testing
- epoetin alfa
- Sponsor
- Janssen-Ortho Inc., Canada
Atelectasis
Perioperative Atelectasis in Orthopaedic Surgery: a Prospective Study
This study aims at comparing a perioperative pulmonary atelectasis score, measured by pulmonary ultrasound, in patients operated undergoing orthopedic surgery under general anesthesia, spinal anesthesia or peripheral nerve block.
- Trial name
- ATELHO (NCT05384795)
- Testing
- Lung ultrasound
- Where
- Switzerland
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Eric Albrecht
Critical-size Bone Defect
Management of Bone Loss in Orthopaedic Surgery Using the Masquelet Technique or Transport Nails
This is a single-center prospective observational study comparing two techniques for reconstructing bone loss in the lower limbs.
- Trial name
- EPSOCOT (NCT07389681)
- Testing
- Data collection and self-administered questionnaire.
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Bordeaux
Arthroplasty, Osteoarthritis
Efficacy of Preoperative Muscle Training on Postoperative Orthopaedic Surgery Recovery
The purpose of this study is to assess the effectiveness of a preoperative muscle training program on hip or knee TJA (Total Joint Arthroplasty).
- Trial name
- NCT03483519
- Testing
- Rehabilitation, Standard of Care
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Ottawa Hospital Research Institute
Orthopedic Disorder
Comparative Evaluation of Lumbar Plexus and Suprainguinal Fascia Iliaca Compartment Blocks
The investigators aim to compare the use of a suprainguinal fascia iliaca compartment block vs lumbar plexus block as an adjunct to general anesthesia in pediatric patients undergoing orthopedic procedures involving the hip or…
- Trial name
- NCT03746951
- Testing
- Ropivacaine Hcl 0.5% Inj Vil 20Ml
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Nationwide Children's Hospital
Quality of Life, Surgery
Determination of the Effect of Puzzle Use in Elderly Patients
The aim of this study is to determine the effects of the use of a simple, reliable and cost-effective puzzle on post-operative cognitive function changes, postoperative recovery, and quality of life using questionnaires and…
- Conditions
- Quality of Life, Surgery, Postoperative Confusion, Cognitive Dysfunction
- Trial name
- NCT05796830
- Testing
- Puzzle application
- Volunteers
- healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Delirium, Anesthesia Emergence, Delirium
The Efficacy of Oral Melatonin in Preventing Postoperative Delirium for Patients Undergoing Orthopedic Surgery Under General Anesthesia
Postoperative delirium is a complication that should not be underestimated. As it elaborates many complications that could be avoided when an accurate assessment of the risk factors and interventional measures are taken…
- Trial name
- NCT05236907
- Testing
- Melatonin, No intervention, Midazolam
- Where
- 2 sites in Iraq
- Volunteers
- 36 people
- Sponsor
- University of Baghdad
Perioperative Anxiety, Perioperative Pain Management
Evaluation of the Effectiveness of Virtual Reality as an Adjunct to Standard Care in Managing Perioperative Anxiety and Pain in Patients Undergoing Lower Limb Orthopedic Surgery Under Spinal Anesthesia
The goal of this clinical trial is to evaluate whether virtual reality (VR) can effectively reduce perioperative anxiety and pain in patients undergoing lower limb orthopedic surgery under spinal anesthesia.
- Conditions
- Perioperative Anxiety, Perioperative Pain Management, Hemodynamic Stability, Satisfaction
- Trial name
- NCT07134764
- Testing
- Virtual reality session
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sfax
Preoperative Anxiety, Psychological Stress
Effect of Lavender Aromatherapy on Preoperative Anxiety, Stress, and Depression in Orthopedic Surgery Patients
This study evaluates whether inhalation aromatherapy with lavender essential oil can reduce anxiety, stress, and depression in adult patients before orthopedic surgery in Jordan.
- Conditions
- Preoperative Anxiety, Psychological Stress, Depressive Symptoms, Orthopedic Surgery Patients
- Trial name
- LAV-ORTHO (NCT07513831)
- Testing
- Lavender Essential Oil Inhalation
- Where
- Jordan
- Volunteers
- 128 people
- Sponsor
- Al-Zaytoonah University of Jordan
Osteoarticular Infection
Treatment of Methicillin-sensitive Staphylococcus Aureus (MSSA)
Background: One of the leading causes of peri-operative osteoarticular infections (OAI) is Staphylococcus aureus. Treatment usually requires surgical debridement in association with appropriate antibiotic therapy.
- Trial name
- CLINDOS (NCT01500837)
- Testing
- association of RIFAMPIN + CLINDAMYCIN, association of LEVOFLOXACIN+ CLINDAMYCIN
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hip Orthopaedic
Cohort Study of Perioperative Ultrasound and Delirium Following Hip Surgery
About this study This is a single-center prospective observational cohort study involving older adults undergoing hip surgery. The investigators will collect clinical and ultrasound-related information without changing routine…
- Trial name
- UPED (NCT07820007)
- Testing
- Peri-operative observational data collection of bedside ultrasound and hemodynamic parameters
- Where
- China
- Volunteers
- 620 people
- Sponsor
- Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine
Orthopedic Surgery
Efficacy of CHX Cloths Versus CHX Soaps for Bathes Before Orthopedic Surgery
Surgical site infections (SSI) in orthopedic surgery are rare events but associated with great morbidity as well as a significant additional cost.
- Trial name
- POL (NCT05120739)
- Testing
- 2% CHX cloths
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Grenoble
Polydactyly Toe, Thumb Hypoplasia
Clonidine for Tourniquet-related Pain in Children
This study is designed as a randomized, placebo-controlled, double-blinded, clinical trial with two parallel groups. This study investigates the association between a single dose of the drug, Clonidine, and the total amount of…
- Conditions
- Polydactyly Toe, Thumb Hypoplasia, Trigger Finger, Polydactyly; Fingers
- Trial name
- CLOTCH (NCT04564430)
- Testing
- Catapresan, Saline
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Arthroplasty, Replacement, Knee, Osteoarthritis, Knee
Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement
Brief Summary The goal of this clinical trial is to learn if nurse-led telehealth consultations can help detect complications and support recovery after total knee replacement surgery.
- Trial name
- NCT07058623
- Testing
- Nurse-Led Telehealth Consultation, Traditional In-Person Nursing Consultation
- Where
- Hong Kong
- Volunteers
- 98 people
- Sponsor
- Hospital Authority, Hong Kong