Clinical trials: Orthopedic Surgery
Pneumonia, Urinary Tract Infections
Prehospital Assessment Units - a Matched Cohort Study
This study aimed to evaluate the prehospital assessment unit (PAU) by admission within 48 hours, 7 days, respectively and on survival.
- Conditions
- Pneumonia, Urinary Tract Infections, Fall, Infections
- Trial name
- NCT05654909
- Testing
- Prehospital assessment unit
- Where
- Denmark
- Volunteers
- 10,849 people
- Sponsor
- Prehospital Center, Region Zealand
Pain, Pain, Postoperative
Effect of Quranic Recitation and Classical Music on Pain Intensity and Interleukin-6 Levels After Lower Limb Orthopedic Surgery With Intrathecal Anesthesia
The goal of this study is to determine the effect of murottal and classical music on postoperative pain intensity and interleukin 6 levels in patients undergoing lower extremity orthopedic surgery with spinal anesthesia.
- Conditions
- Pain, Pain, Postoperative, Inflammation, Orthopedic Surgical Procedures
- Trial name
- QRCM (NCT06713044)
- Testing
- Murottal Therapy Intervention Name: Murottal (Islamic verse recitation), Classical Music Therapy Intervention Name: Classical Music Listening, Standard Care (in control arm)
- Where
- Indonesia
- Volunteers
- 33 people
- Sponsor
- Universitas Jenderal Soedirman
Outpatient Orthopedic Surgery
Preoperative Education for Less Outpatient Pain After Surgery (PELOPS)
In 2015, more than 50% of surgical procedures were performed in outpatient settings. Successful pain management after outpatient surgery is crucial, and requires a perfect cooperation between caregivers and patients, with clear…
- Trial name
- PELOPS (NCT03754699)
- Testing
- Educational intervention, Standard information
- Where
- France
- Volunteers
- 412 people
- Sponsor
- Hospices Civils de Lyon
Deformity of Bone
Archive of Custom-made Guides for Orthopedic Surgery
The present study aims to design, develop and test an electronic archive to be able to track over time the so-called Patient-Specific Cutting Guides for Orthopedics (in English often known as ' Pa-tient-Specific Cutting Guides').
- Trial name
- NCT07893132
- Testing
- Archive
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Ortopedico Rizzoli
Surgery, Acute Phase Reaction
Neuroinflammation and Cognitive Dysfunction After Orthopedic Surgery
The primary hypothesis that orthopaedic surgery induces a neuroinflammatory response within 48 hours after elective hip or knee surgery and that there is an association between exaggerated CNS inflammatory response or impaired…
- Trial name
- NCT02759965
- Where
- 2 sites in Sweden
- Volunteers
- 34 people
- Sponsor
- Karolinska University Hospital
Total Fluid Volume Increased
Evaluate the Nephrotoxicity by 6% Hydroxyethyl Starch 130/0.4 in Old Patients During Orthopaedic Surgery
Hydroxyethyl starch (HES) is commonly used as plasma expander during surgery but may be nephrotoxic as seen in studies in patients with sepsis.
- Trial name
- NCT02361736
- Testing
- Hydroxyethyl Starch, Lactate Ringers
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Yuanyuan Zhang
Orthopedic Surgery
The Effect of Progressive Relaxation Exercise on Fatigue and Comfort Level After Major Orthopedic Surgery
This study was planned to determine the effect of progressive relaxation exercise to be applied after major orthopedic surgery on post-operative fatigue and comfort level.
- Trial name
- NCT05295199
- Testing
- Progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Aksaray University
Orthopedic Disorders
The Different Analgesic Potency of Volatile Anesthetics at Equi-MAC
The aim of this clinical trial is to evaluate the difference of analgesic potency of sevoflurane and desflurane at equi-minimum alveolar concentration using a surgical pleth index.
- Trial name
- NCT02609802
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 77 people
- Sponsor
- Kangbuk Samsung Hospital
Orthopedic Disorder, Arthropathy of Knee
Total Knee Arthroplasty and Clinical Findings
Knee osteoarthritis is a common disease that causes pain and loss of function. Total Knee Arthroplasty (TKA) is a frequently used surgical method in the treatment of severe knee osteoarthritis.
- Conditions
- Orthopedic Disorder, Arthropathy of Knee, Pain, Joint, Proprioception
- Trial name
- NCT04481711
- Testing
- Total Knee Arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Karadeniz Technical University
Physiological Stress
Physiologic Burden to the Surgeon During Orthopaedic Surgery
The investigator's plan to quantify the physiologic impact of orthopaedic surgery on the surgeon and operating team.
- Trial name
- NCT06180044
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Utah
Osteoarthritis, Gonarthrosis
Multimodal Geriatric Pre-authorization Before Scheduled Orthopedic Surgery
The main objective of this multicentric, prospective and interventional study is to assess the feasibility of multimodal prehabilitation in patients aged 75 years or older with surgical indication for coxarthrosis or severe…
- Trial name
- PRE4OS (NCT05062109)
- Testing
- Multimodal geriatric prehabilitation
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Gérond'if
Pediatric Procedural Sedation
Intranasal Dexmedetomidine vs. Oral Chloral Hydrate for Pediatric Orthopedic Procedural Sedation
This prospective randomized controlled study will compare the effectiveness and safety of intranasal dexmedetomidine with oral chloral hydrate for procedural sedation in children undergoing painful orthopedic manipulation.
- Trial name
- NCT07768566
- Testing
- Dexmedetomidine, Chloral Hydrate
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Childrens Hospital
Rupture of Anterior Cruciate Ligament, Osteoarthritis
Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction (ACLR): Onsite Follow-up
In this study we will examine patients who have undergone unilateral ACL reconstruction surgery to determine which structural and functional characteristics of the knee two and ten years post reconstruction surgery, aspects of…
- Trial name
- MOON-Onsite (NCT00478894)
- Where
- 4 sites in United States
- Volunteers
- 432 people
- Sponsor
- Vanderbilt University
Bone Neoplasm of Hip (Diagnosis), Orthopedic Disorder
Evaluation of the Ability of CT-based Finite Element Analysis (CTFEA) to Predict Fractures in Patients With Metastases: a Randomized Controlled Study.
Patients with metastases to proximal femur, who are evaluated fr the risk of pathologic fracture in order to decide on preventive fixation vs follow-up constitute the study population. The patients will be randomized in two arms.
- Conditions
- Bone Neoplasm of Hip (Diagnosis), Orthopedic Disorder, Bone Metastases, Proximal Femoral Metaphyseal Abnormality
- Trial name
- ZYCTFEA (NCT03453905)
- Testing
- CTFEA, Conventional decision algorithm
- Volunteers
- 162 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Soft Tissue Sarcoma Adult
Study of a Cohort of Cases of Synovial Sarcoma Treated in the Orthopedic Surgery and Traumatology Department of the Hospital de Sant Pau Between 1983 and 2016
The main objectives of this study are the following: to describe the prognostic factors of survival of synovial sarcoma in patients treated by the orthopedic surgery unit oncologic of the orthopedic surgery and traumatology…
- Trial name
- NCT03833037
- Testing
- Soft tissue sarcomas in adults
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Anesthesia
Anesthesia for Emergency Orthopedic Surgery
The aim of this retrospective study is to evaluate the preferred anaesthesia techniques in our clinic for emergency orthopedic surgery at a 1 year period.
- Trial name
- NCT02820922
- Testing
- Orthopedic
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Sakarya University
Orthopaedic Surgery
An mHealth Self-Management Program to Decrease Postoperative Symptom Distress
The purposes of this study are to determine if use of the Postoperative Care at Home (PoCAH) tailored self-management program delivered via mobile technology (a mobile app) after discharge to home will result in: 1) fewer and/or…
- Trial name
- NCT02610894
- Testing
- mHealth application (PoCAH), As usual standard discharge and care instructions
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jan Odom Forren
Knee Disease, Knee Infection
F18-MHF: Implants-Associated Infection Detection
Following intravenous injection of [F-18]MHF as a bolus, dynamic PET imaging of the lower limbs will be acquired for approximately 90 minutes. The acquired images will be processed and viewed on a MIMVista or similar workstation.
- Trial name
- NCT05889286
- Testing
- [F-18]MHF
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Emory University
Osteoarthritis, Knee, Joint Diseases
Comparative Study of Navigation-assisted OrthoPilot® Elite and Robotic-assisted MAKO® Total Knee Arthroplasty
Randomized, controlled, single center observational study to compare the safety and performance of navigation-assisted OrthoPilot Elite and robotic-assisted MAKO total knee arthroplasty (TKA).
- Conditions
- Osteoarthritis, Knee, Joint Diseases, Rheumatoid Arthritis of Knee, Posttraumatic Arthropathy
- Trial name
- ORMAK (NCT05980442)
- Testing
- Navigated total knee arthroplasty, Robot assisted total knee arthroplasty
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Aesculap AG
Grafting, Bone
Osteoconduction Potential of an Injectable Calcium Phosphate in Orthopaedic Surgery in Fillings of Osseous Defects
The purpose of this non-comparative study is to test, for the first time, the bioactivity of a new "ready to use" calcium phosphate biomaterial in fillings of little losses of osseous substance from various origins, such as…
- Trial name
- NCT00206791
- Testing
- MBCP-Gel (tm), MBCP Gel
- Where
- 4 sites in France
- Volunteers
- 3 people
- Sponsor
- Biomatlante