Clinical trials: Orthoses, open to volunteers
Pareses, Lower Extremity
C-Brace Prospective Registry
To gather prospective safety and effectiveness data for the C-Brace System following the standard of care.
- Trial name
- NCT04640584
- Testing
- C-Brace
- Where
- 76 sites in United States, Australia and 2 more
- Volunteers
- 250 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Knee Osteoarthritis
A Multi-centre Study of Shoe-worn Insoles and Knee Osteoarthritis
Shoe-worn insoles (also known as orthotics) can provide symptomatic relief for people with knee osteoarthritis. However, given they act at the feet, and given that many people with knee osteoarthritis also report foot pain, it is…
- Trial name
- MULTIWEDGE (NCT06251167)
- Testing
- Lateral wedge insoles (LWIs), Lateral wedge plus custom arch support (LWAS)
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University of British Columbia
Hallux Valgus
Foot Orthoses in the Treatment of Painful Hallux Valgus
This randomized pilot feasibility trial will evaluate the feasibility of conducting a full-scale randomized controlled trial comparing custom-made, prefabricated, and sham foot orthoses in people with painful hallux valgus.
- Trial name
- NCT07781735
- Testing
- Podiatric Education, Exercise, Prefabricated foot orthoses
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Université du Québec à Trois-Rivières
Spondylolisthesis, Orthosis
Effects of Orthosis & Exercise on Spondylolisthesis
In the treatment of spondylolisthesis, conservative methods are initially preferred unless severe neurological symptoms are present; surgical treatment is only performed in refractory cases lasting at least 3-6 months.
- Conditions
- Spondylolisthesis, Orthosis, Exercise Training
- Trial name
- NCT06989138
- Testing
- Stabilitation Exercise, Conventional Exercise, Orthosis
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Medipol University
Lower-limb Orthoses, Osteoarthritic Knee Pain
Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses Renewal
The overall goal of this project is to establish a novel design and control paradigm for modular, partial-assist powered orthoses (exoskeletons) to enhance voluntary lower-limb motion and manage pain in broad patient populations.
- Conditions
- Lower-limb Orthoses, Osteoarthritic Knee Pain, Osteoarthritis (OA) of the Knee
- Trial name
- NCT07673328
- Testing
- Modular powered orthosis
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cerebral Palsy
Comparison of Two Ankle Foot Orthosis on Mobility, Participation and Adhesion in Childrend With Cerebral Palsy
Children with cerebral palsy (CP) present a variety of motor impairments and activity limitations. Plastic ankle-foot orthoses (pl-AFO) are frequently prescribed to improve their gait.
- Trial name
- DynamicPC (NCT07301593)
- Testing
- orthosis use
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cerebral Palsy (CP), Hand Grip Strength
Effects Of Spiral Strapping Systems On Upper Limb Function In Unilateral Spastic Cerebral Palsy
The purpose of this clinical study is to learn whether two different spiral strapping systems can improve arm and hand use in children with unilateral spastic cerebral palsy.
- Conditions
- Cerebral Palsy (CP), Hand Grip Strength, Upper Extremity Function, Spasticity
- Trial name
- NCT07418710
- Testing
- TheraTogs® Spiral Strapping System, TogRite™ Spiral Strapping System, Upper Limb Rehabilitation and Home Exercise Program
- Volunteers
- 27 people
- Sponsor
- Abant Izzet Baysal University
Stroke, Hemiparesis
MyHand 2: An Active Hand Orthosis for Stroke Patients
This study is designed to further develop and test the hardware and software components of the MyHand device based on user feedback and results from our pilot study.
- Trial name
- MyHand 2 (NCT04436042)
- Testing
- MyHand Device
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Columbia University
Finger Joint Deformities, Tendon Injuries
Conservative Treatment With Relative Motion Flexion Orthosis for Boutonniere Injuries in Fingers
Boutonnière injuries involve damage to the central slip of the extensor tendon over the proximal interphalangeal (PIP) joint (zone III) of the finger.
- Conditions
- Finger Joint Deformities, Tendon Injuries, Hand Injuries, Extensor Tendons of Finger Anomalies
- Trial name
- NCT07921927
- Testing
- Relative Motion Flexion (RMF) orthosis intervention group
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Lund University Hospital
Deformational Plagiocephaly, Deformational Posterior Plagiocephaly
Effectiveness of Repositioning and Cranial Remolding in Infants With Cranial Deformation
This study will examine how effective caregiver's repositioning strategies are in correcting an infant's deformational cranial shape, as well as the effectiveness of the use of a custom cranial remolding orthosis for treatment of…
- Conditions
- Deformational Plagiocephaly, Deformational Posterior Plagiocephaly, Brachycephaly, Torticollis
- Trial name
- NCT05917678
- Testing
- Repositioning Therapy, Cranial Remolding Orthosis
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Flaccid Paresis, Spastic Paresis
Comparing Digitally and Traditionally Made Ankle Foot Orthoses
The research is being done to compare two methods of creating AFOs: 1. The traditional method, which involves manually creating a mold from a plaster cast of the client's limb. This is time-consuming and labor-intensive; and 2.
- Conditions
- Flaccid Paresis, Spastic Paresis, Cerebral Palsy, Stroke
- Trial name
- NCT06828653
- Testing
- Part A First Wear Period: Traditional AFO(s), Part A First Wear Period: Digital AFO(s), Part A Second Wear Period: Traditional AFO(s)
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Symphysis Pubis Dysfunction, Pregnancy
Effects of Pelvic Floor Muscle Training and a Modified Lumbopelvic Belt on Pain, Kinesiophobia, and Functional Status in Pregnant Women With Symphysis Pubis Pain
The aim of this study is to investigate the effects of pelvic floor muscle training and a modified lumbopelvic belt on pain, kinesiophobia, and functional status in pregnant women with symphysis pubis pain.Although the power…
- Conditions
- Symphysis Pubis Dysfunction, Pregnancy, Pregnancy Complication
- Trial name
- Pubic Pain (NCT07919548)
- Testing
- educational program, modified lumbopelvic belt
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Multiple Sclerosis
VR and Orthoses for Rehabilitation in Multiple Sclerosis
This non-drug, non-medical device, interventional study explores the feasibility of integrating virtual reality (VR) with wearable sensors to support gait training using a passive orthosis in individuals with multiple sclerosis…
- Trial name
- VIRTUE (NCT07096700)
- Testing
- VR and walking brace-based gait rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 12 people
- Sponsor
- Azienda Usl di Bologna
Stroke, Stroke Rehabilitation
Evaluating Functional Outcomes of 3D-Printed Splints in Post-Stroke Upper Limb Recovery
This study aims to evaluate the upper limb motor recovery using a 3D-printed dynamic orthosis compared to a conventional one as part of a rehabilitation program in individuals with chronic stroke.
- Conditions
- Stroke, Stroke Rehabilitation, Hemiparesis of the Upper Limb Following Stroke
- Trial name
- 3D-splint (NCT07243314)
- Testing
- 3D Printed splint, conventional splint
- Where
- Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- King Saud University
Trigger Finger
ESWT vs Orthosis in Trigger Finger
Recently, two works have proposed the application of Extracorporeal Shock Waves Therapy (ESWT) in the treatment of trigger finger. Yildirim and colleagues (2016) compared shock waves with corticosteroid infiltration.
- Trial name
- SWinTF (NCT06737601)
- Testing
- shock waves
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Cervical Spine Fractures, Cervical Spine Injury
Study on Orthosis in Cervical Spine Fracture Treatment
Background and Purpose: Neck fractures affect over 1,100 people in Sweden each year, with the majority being frail older adults.
- Conditions
- Cervical Spine Fractures, Cervical Spine Injury, Rigid Collar
- Trial name
- SOFT (NCT06848660)
- Testing
- A rigid cervical collar
- Where
- 6 sites in Sweden
- Volunteers
- 616 people
- Sponsor
- Uppsala University Hospital
Metatarsalgia
Randomized Controlled Trial of Custom Foot Orthoses for Chronic Forefoot Pain
Background Chronic metatarsalgia (CM) causes significant pain and disability, affecting quality of life. Foot orthoses (FOs) including medially wedged designs with a metatarsal pad decrease excessive plantar pressure under the…
- Trial name
- NCT06962475
- Testing
- Podiatric advice, Customized foot orthoses
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Université du Québec à Trois-Rivières
Adolescent Idiopathic Scoliosis (AIS), Adherence
Support System Design for Adolescent Scoliosis Orthosis Wear
This study focuses on improving the daily lives and treatment outcomes of teenagers diagnosed with Adolescent Idiopathic Scoliosis (AIS).
- Trial name
- NCT07574229
- Testing
- Digital Support System for AIS Orthosis Wear, Conventional Treatment Control Group
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Hyperkyphosis
Efficacy of Spinal Orthoses on Mobility in Older Adults With Hyperkyphosis
This study investigates whether wearing a thoracic spinal orthosis (back brace) improves functional mobility in physically active older adults (60 years and older) with thoracic hyperkyphosis, an excessive forward curvature of…
- Trial name
- NCT06970470
- Testing
- Triple-Adjustable Posture Corrector Manufacturer: Mercur®, Santa Cruz do Sul, Brazil, Generation Dynamic Osteoporosis Brace Manufacturer: Bort®, Weinstadt, Germany
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Chronic Stroke
Exoskeleton Research: Myoelectric Orthosis for Rehab of Severe Chronic Arm Motor Deficits
This study will evaluate the effects of combining motor learning-based therapy with use of the MyoPro , a wearable exoskeletal myoelectrically controlled orthotic device.
- Trial name
- NCT05296408
- Testing
- motor learning based therapy, MyoPro, Home Exercise Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- VA Office of Research and Development