Clinical trials: Osa Syndrome
Obstructive Sleep Apnea (OSA)
Vent Flow Study of Prototype Nasal CPAP Mask
As continuous positive airway pressure is the treatment choice for OSA, a mask is vital in ensuring the effectiveness of therapy delivery. The study will evaluate the performance of a new mask system with diffuse vent technology.
- Trial name
- GVFECT (NCT02805777)
- Testing
- CPAP mask
- Sponsor
- ResMed
OBSTRUCTIVE SLEEP APNEA
Obstructive Apnea in Patients Submitted to Partial Laryngectomy
The investigators intend to study the prevalence of obstructive apnea in patients submitted to partial laryngectomy by larynx cancer. Volunteers will be evaluated using polissonografy.
- Trial name
- NCT01157286
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital do Servidor Publico Estadual
Obstructive Sleep Apnea
Promoting Continuous Positive Airway Pressure (CPAP) Adherence
The proposed research will evaluate new approaches to improving the ability of patients with obstructive sleep apnea (OSA), a breathing disorder during sleep, to use continuous positive airway pressure (CPAP), a medical device…
- Trial name
- NCT01335854
- Testing
- Web-based Access to CPAP Data, Web-based Access to CPAP Data with Financial Incentive
- Where
- 2 sites in United States
- Volunteers
- 135 people
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea
DeVilbiss AutoAdjust With SmartFlex Comparative Study
There will be equivalent therapeutic effectiveness between SmartFlex and standard modes when using the DeVilbiss AutoAdjust device.
- Trial name
- NCT01203956
- Testing
- SmartFlex, Standard
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- DeVilbiss Healthcare LLC
Sleep Apnea
Cardiac Dysfunction in Obstructive Sleep Apnea Patients: Prevalence of and Effect of nCPAP
The aim of this study is to clarify the influence of obstructive sleep apnea syndrome on left ventricular function using echocardiographic parameters including the myocardial performance index (Tei-index), and to determine the…
- Trial name
- NCT00503945
- Testing
- Nasal continuous positive airway pressure (nCPAP)
- Where
- Japan
- Volunteers
- 27 people
- Sponsor
- Nagasaki University
Sleep Apnea, Obstructive
The PREDICTOR Study: Assessing Diagnostic Predictors of Airway Collapse in Patients With Obstructive Sleep Apnea
This study is an exploratory, multicenter study of up to 300 subjects diagnosed with obstructive sleep apnea who are being evaluated for airway surgery.
- Trial name
- PREDICTOR (NCT05428839)
- Testing
- Pharyngeal width measurement
- Where
- 10 sites in United States
- Volunteers
- 300 people
- Sponsor
- Inspire Medical Systems, Inc.
Obstructive Sleep Apnea
Community Health Advocates for Motivating PAP Use in Our Neighborhoods.
The purpose of this research is to compare the impact of motivational enhancement therapy (MET), delivered by culturally congruent community health care workers (CHWs) versus usual care patients with previously untreated…
- Trial name
- Champion (NCT06047353)
- Testing
- Motivational Enhancement Therapy, Positive Airway Pressure (PAP) therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Miami
Sleep Apnea Hypopnea Syndrome, Physical Activity
Effect of an Aerobic Exercise Program in Patients With Moderate-severe Sleep Apnea
In this paper, it is postulated that in sedentary patients with moderate-severe sleep apnea diagnosed by a sleep test, an increase in physical activity stimulated by the use of a pedometer during a period of 6 months can reduce…
- Trial name
- SAH-2014 (NCT03997877)
- Testing
- Physical activity
- Where
- Spain
- Volunteers
- 176 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Obstructive Sleep Apnoea (OSA), Hypoventilation Syndrome
Sleep-disordered Breathing Database
The goal of this study is to collect clinical data on patients who have had a sleep study and are given a diagnosis of a sleep related breathing disorder such as obstructive sleep apnoea.
- Trial name
- NCT07402603
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Obstructive Sleep Apnea
Nasal Budesonide in Children With Rhinitis and/or Mild Obstructive Sleep Apnea Syndrome
-Intranasal budesonide therapy may lead to improved symptoms and sleep study findings in children with mild obstructive sleep apnea with and without allergic rhinitis that would not be treated with T\&A.
- Trial name
- NCT00560586
- Testing
- Budesonide
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Louisville
Sleep Disordered Breathing, Obstructive Sleep Apnea
The Natural History and Outcome of Sleep Disordered Breathing in Children
Sleep-disordered breathing in children is characterized by recurrent events of partial or complete upper airway obstruction during sleep, resulting in disruption of normal gas exchange (intermittent hypoxia and hypercapnia) and…
- Trial name
- NCT02043353
- Where
- Israel
- Volunteers
- 2,856 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Chronic Kidney Diseases, OSAS (Obstructive Sleep Apneas Syndrome)
The Outcome of Chronic Kidney Disease Patients With Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea (OSA) is highly prevalent in chronic kidney disease (CKD) patients and strongly linked to obesity, metabolic syndrome, and type 2 diabetes.
- Trial name
- NCT06971874
- Testing
- No intervention
- Where
- China
- Volunteers
- 356 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Obstructive Sleep Apnea
Lifestyle Modification Program to Treat Obstructive Sleep Apnea Patients
Obstructive sleep apnea syndrome (OSAS) is a common form of sleep-disordered breathing (SDB) characterized by repetitive episodes of cessation of breathing during sleep due to upper airway collapse.
- Trial name
- OSA (NCT01384760)
- Testing
- Lifestyle modification, Simple lifestyle advice
- Where
- China
- Volunteers
- 185 people
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea
Hypnotics to Improve Polysomnography Yield: Eszopiclone vs Ramelteon?
This study is being conducted to determine if eszopiclone is as effective as ramelteon when used as a pre-medication (sleeping pill) in sleep studies performed to diagnose and treat sleep apnea.
- Trial name
- NCT00811746
- Testing
- Rozerem (Ramelteon), Lunesta (Eszopiclone), Historical Controls
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Southern California Institute for Research and Education
Multiple Sclerosis, Obstructive Sleep Apnea
Prevalence and Impact of Obstructive Sleep Apnea in Multiple Sclerosis
This study will evaluate the influence of sleep apnea on clinical and radiological features of MS. Sleep apnea is associated with hypoxemia during sleep, which is likely detrimental to MS.
- Trial name
- SOMNUS (NCT04603196)
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Beth Israel Deaconess Medical Center
Sleep Apnea, Obstructive
Treatment Study of Soft Palatal Implants in Obstructive Sleep Apnea
The purpose of the study is to compare the effectiveness of soft palatal implants with placebo and continuous positive airway pressure treatment in obstructive sleep apnea.
- Trial name
- NCT00263770
- Testing
- soft palate implant, Positive airway pressure (PAP)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Mayo Clinic
Severe Obstructive Sleep Apnea (Apnea Hypopnea Index > 30 Events/Hour), Hypertension
Study of Cardiovascular Disease and Obstructive Sleep Apnea
The purpose of this study is to determine if two medicines (allopurinol and losartan) can influence heart and blood vessel health compared to placebo in patients with sleep apnea who are using continuous positive airway pressure…
- Trial name
- CVD/OSA (NCT01637623)
- Testing
- Losartan, Allopurinol
- Where
- 4 sites in United States
- Volunteers
- 87 people
- Sponsor
- University of Wisconsin, Madison
Obstructive Sleep Apnea, PTSD
Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD
Approximately 20 million Americans suffer from Obstructive Sleep Apnea (OSA) creating risks for major health problems, including dementia, heart attack, and stroke.
- Conditions
- Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
- Trial name
- NCT02641496
- Testing
- CBT-OSA, Sleep Education
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea, Diabetes Mellitus
Rapid Eye Movement Related OSA in Diabetic Versus Non-Diabetic Patients Treated With PCI
The primary objective of the Sleep and Stent II is to determine the prevalence of REM-OSA in DM versus non-DM patients undergoing clinically indicated PCI.
- Conditions
- Obstructive Sleep Apnea, Diabetes Mellitus, Coronary Artery Disease
- Trial name
- NCT03479788
- Where
- Singapore
- Volunteers
- 204 people
- Sponsor
- National University of Singapore
Obstructive Sleep Apnea Syndrome
Validation of Sleep Monitoring Algorithm Based on Smart Watches
In recent years, wearable devices are booming to enable not only the health monitoring but also the sleep efficiency assessment.
- Trial name
- NCT06696196
- Testing
- smart watches(wearable devices)
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital